UEHARA Natsumi 上原奈津美

… Alternative Names

Natsumi Uehara 上原奈津美

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Researcher Number	40570502
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2018 – 2024: 神戸大学, 医学部附属病院, 助教 2017: 神戸大学, 医学部附属病院, その他 2016: 神戸大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords	Principal Investigator マイトファジー / NDUFA1 / 内耳 / 難聴 / ミトコンドリア / 抗利尿ホルモン / アクアポリン / 内リンパ水腫 / メニエール病 Except Principal Investigator 頭頸部癌 … More / 頭頸部がん / 抗PD-1抗体 / 遺伝子導入 / CD80 / B7 / 免疫チェックポイント阻害剤 / 扁平上皮癌 / アデノウイルスベクター / 遺伝子治療 / adenoviral vector / squamous cell carcinoma / immune checkpoint / B-7 / Ki-67陽性CD8陽性T細胞 / 制御性T細胞 / B7-1遺伝子 / 腫瘍免疫 / 放射線治療 / 共刺激分子 / 免疫チェッックポイント阻害薬 / B7遺伝子 / CD90 / 共刺激因子 / ウィルス / ウイルス / 遺伝子 / 癌 / MIDKINE / 増殖制限型アデノウイルス / 制限増殖型アデノウイルス / siRNA / EGFR / Midkine / バイオマーカー / マイクロRNA / エクソソーム Less

ミトコンドリア病モデル内耳細胞を用いたミトコンドリア難聴の病態解明Principal Investigator
- Principal Investigator
  
  上原奈津美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kobe University
免疫チェックポイント阻害剤と遺伝子治療の併用による頭頸部癌に対する治療法の開発
- Principal Investigator
  
  丹生健一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kobe University
Localization of Aquaporin-2 regulation by vasopressin in Meniere's disease.Principal Investigator
- Principal Investigator
  
  Natsumi Uehara
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kobe University
Combined effects of co-stimulatory molecule gene transfer and radiotherapy on immune checkpoint inhibitors
- Principal Investigator
  
  Ken-ichi Nibu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kobe University
Midkine-Promoter based Conditionally Replicative Adenovirus expressing siRNA against EGFR for Head and Neck Cancer
- Principal Investigator
  
  Nibu Ken-ichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kobe University
Novel biomaker for head and neck cancer in exosome
- Principal Investigator
  
  Ken-ichi Nibu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2020 2018

All Journal Article Presentation

[Journal Article] Induction of Immunological Antitumor Effects by the Combination of Adenovirus-Mediated Gene Transfer of B7-1 and Anti-Programmed Cell Death-1 Antibody in a Murine Squamous Cell Carcinoma Model2024
- Author(s)
  Hara Makiko、Saburi Sumiyo、Uehara Natsumi、Tsujikawa Takahiro、Kubo Mie、Furukawa Tatsuya、Teshima Masanori、Shinomiya Hirotaka、Hirano Shigeru、Nibu Ken-ichi
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 7 Pages: 1359-1359
- DOI
  10.3390/cancers16071359
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24494
[Journal Article] Genetic background in late-onset sensorineural hearing loss patients2021
- Author(s)
  Uehara Natsumi、Fujita Takeshi、Yamashita Daisuke、Yokoi Jun、Katsunuma Sayaka、Kakigi Akinobu、Nishio Shin-ya、Nibu Ken-ichi、Usami Shin-ichi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 67 Issue: 4 Pages: 223-230
- DOI
  10.1038/s10038-021-00990-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18768
[Journal Article] Oncolytic effect of Midkine promoter-based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T8912020
- Author(s)
  Uehara Natsumi、Otsuki Naoki、Kubo Mie、Kitamoto Junko、Kojima Yasutaka、Teshima Masanori、Shinomiya Hirotaka、Shirakawa Toshiro、Nibu Ken-ichi
- Journal Title
  
  Cancer Reports
  
  Volume: 2 Issue: 3
- DOI
  10.1002/cnr2.1231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03804
[Journal Article] Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA combined with cisplatin inhibits cellular growth and induces apoptosis in HPV-positive head and neck cancer cells2018
- Author(s)
  Kojima Y, Otsuki N, Kubo M, Kitamoto J, Takata E, Saito H, Kosaka K, Morishita N, Uehara N, Shirakawa T, Nibu KI
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 25 Issue: 9-10 Pages: 274-283
- DOI
  10.1038/s41417-018-0024-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05481
[Presentation] Clinical Characteristics & Hearing Impairment in Mitochondrial DNA Mutation2024
- Author(s)
  Natsumi Uehara
- Organizer
  ARO 47th Annual MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16912
[Presentation] 扁平上皮癌に対するB7遺伝子導入と免疫チェックポイント阻害剤の併用効果に関する検討2023
- Author(s)
  原真貴子　上原奈津美　辻川敬裕　丹生健一
- Organizer
  第47回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-23K24494
[Presentation] ミトコンドリア病母体から出生した児の臨床症状に関する検討2023
- Author(s)
  上原奈津美
- Organizer
  第18回日本小児耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K16912
[Presentation] ミトコンドリアDNA変異症例の臨床的特徴と聴覚障害の検討2023
- Author(s)
  上原奈津美
- Organizer
  第33回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K16912
[Presentation] 遅発性感音難聴患者における聴力型別遺伝学的背景の検討2022
- Author(s)
  上原奈津美
- Organizer
  第32回日本耳科学会総会
- Data Source
  KAKENHI-PROJECT-22K16912

1. Ken-ichi Nibu (20251283)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 大月直樹 (40343264)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 井之口豪 (10457046)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Takeshi Fujita (90533711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 四宮弘隆 (00725385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 手島直則 (10749146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SHIRAKAWA toshiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 舟生健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

UEHARA Natsumi 上原 奈津美

Natsumi Uehara 上原 奈津美

Research Projects

Research Products

Co-Researchers

ミトコンドリア病モデル内耳細胞を用いたミトコンドリア難聴の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

免疫チェックポイント阻害剤と遺伝子治療の併用による頭頸部癌に対する治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Localization of Aquaporin-2 regulation by vasopressin in Meniere's disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Combined effects of co-stimulatory molecule gene transfer and radiotherapy on immune checkpoint inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Midkine-Promoter based Conditionally Replicative Adenovirus expressing siRNA against EGFR for Head and Neck Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel biomaker for head and neck cancer in exosome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Induction of Immunological Antitumor Effects by the Combination of Adenovirus-Mediated Gene Transfer of B7-1 and Anti-Programmed Cell Death-1 Antibody in a Murine Squamous Cell Carcinoma Model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic background in late-onset sensorineural hearing loss patients2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncolytic effect of Midkine promoter-based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T8912020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA combined with cisplatin inhibits cellular growth and induces apoptosis in HPV-positive head and neck cancer cells2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Clinical Characteristics & Hearing Impairment in Mitochondrial DNA Mutation2024

Author(s)

Organizer

Data Source

[Presentation] 扁平上皮癌に対するB7遺伝子導入と免疫チェックポイント阻害剤の併用効果に関する検討2023

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリア病母体から出生した児の臨床症状に関する検討2023

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリアDNA変異症例の臨床的特徴と聴覚障害の検討2023

Author(s)

Organizer

Data Source

[Presentation] 遅発性感音難聴患者における聴力型別遺伝学的背景の検討2022

Author(s)

Organizer

UEHARA Natsumi 上原奈津美

Natsumi Uehara 上原奈津美