SAKANO Daisuke 坂野大介

Researcher Number	40571039
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2022: 東京工業大学, 生命理工学院, 助教 2014 – 2015: 東京工業大学, 生命理工学研究科, 助教 2013: 熊本大学, 発生医学研究所, 助教 2012: 熊本大学, 発生医学研究所多能性幹細胞分野, 助教 2011: 熊本大学, 発生医学研究所, COEリサーチ・アソシエイト 2010 – 2011: 熊本大学, 発生医学研究所, COEリサーチ・アソシエート
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Endocrinology
Keywords	Principal Investigator インスリン / 膵臓 / 糖尿病 / β細胞 / ドーパミン / 脱分化 / 分化 / 膵β細胞 / 低分子化合物 / iPS … More / モノアミン / 膵島 / 細胞死 / ROS / モノアミントランスポーター / ヘテロ性 / ドパミン / 再生医療 / iPS細胞 / GPCR / ＶＭＡＴ２ / ＫＯマウス / 複製 / 分泌 / 自己複製 / ES / 膵 / ES・iPS / ｃAMP / VMAT2 / ES・iPS細胞 / 細胞・組織 / 再生医学 / 発生・分化 / スクリーニング / ES細胞 Less

Elucidation of the functional regulatory mechanism of pancreatic islets via monoamine signalingPrincipal Investigator
- Principal Investigator
  
  SAKANO DAISUKE
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Institute of Technology
Elucidation of monoamine-GPCR signal-regulated pancreatic beta cell differentiation and maturation mechanismPrincipal Investigator
- Principal Investigator
  
  Sakano Daisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Institute of Technology
Elucidation of pancreatic beta cell differentiation and maturation mechanism by monoaminesPrincipal Investigator
- Principal Investigator
  
  Sakano Daisuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Institute of Technology
Small compounds promote differentiation of functional insulin producing cellsPrincipal Investigator
- Principal Investigator
  
  SAKANO Daisuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kumamoto University
The establishment of a screening system for low molecular compounds forβcell inducing activity.Principal Investigator
- Principal Investigator
  
  SAKANO Daisuke
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University

[Book] 「膵β細胞再生療法の最前線」『糖尿病・内分泌代謝科』2020
- Author(s)
  坂野大介　粂昭苑
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20K08325
[Book] 糖尿病学20202020
- Author(s)
  坂野大介　粂昭苑
- Total Pages
  8
- Publisher
  診断と治療社
- ISBN
  9784787824639
- Data Source
  KAKENHI-PROJECT-20K08325
[Book] 「膵β細胞・膵島の再生研究」『特集　糖尿病-診断・治療update-』2014
- Author(s)
  坂野大介、粂昭苑
- Total Pages
  6
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-26461036
[Book] 「膵島バイオロジーの新たな展開」『幹細胞を用いた膵β細胞誘導研究』、Diabetes Frontier2014
- Author(s)
  坂野大介、粂昭苑
- Total Pages
  6
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-26461036
[Book] 「膵β細胞研究の進化と展望」『多能性幹細胞から膵β細胞への分化を制御するシグナル』Islet Equality2014
- Author(s)
  坂野大介、粂昭苑
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26461036
[Book] 「糖尿病と代謝」『iPS細胞を用いた膵β細胞研究の最前線』、Diabetes Journal2014
- Author(s)
  坂野大介、粂昭苑
- Total Pages
  6
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-26461036
[Book] 『発生・分化・再生と代謝関連臓器」「多能性幹細胞から膵 β 細胞への分化」『内分泌・糖尿病・代謝内科』24(5)2013
- Author(s)
  坂野大介・粂昭苑
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790949
[Book] 内分泌・糖尿病・代謝内科特集発生・分化・再生と代謝関連臓器多能性幹細胞から膵β 細胞への分化, 第35巻第2号2012
- Author(s)
  2.坂野大介, 白木伸明, 粂昭苑
- Data Source
  KAKENHI-PROJECT-24790949
[Book] 内分泌・糖尿病・代謝内科　特集　発生・分化・再生と代謝関連臓器　多能性幹細胞から膵β細胞への分化、2012
- Author(s)
  坂野大介、白木伸明、粂昭苑、
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790949
[Book] 「iPS細胞による糖尿病医療研究のこれから」-The view of stem cell therapy for type I diabetes-糖尿病2011
- Author(s)
  坂野大介、白木伸明、粂昭苑
- Publisher
  今川企画
- Data Source
  KAKENHI-PROJECT-22790653
[Book] 糖尿病「iPS細胞による糖尿病医療研究のこれから」-The view of stem cell therapy for type I diabetes-2011
- Author(s)
  坂野大介、白木伸明、粂昭苑
- Total Pages
  3
- Publisher
  日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-22790653
[Journal Article] Dopamine negatively regulates insulin secretion through D1-D2 receptor heteromer.2022
- Author(s)
  Uefune F, Aonishi T, Kitaguchi T, Takahashi H, Seino S, Sakano D, Kume S
- Journal Title
  
  Diabetes
  
  Volume: 71 Issue: 9 Pages: 1946-1961
- DOI
  10.2337/db21-0644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19543, KAKENHI-PROJECT-19H04203, KAKENHI-PROJECT-21H02978, KAKENHI-PROJECT-20K08325
[Journal Article] VMAT2 Safeguards β-Cells Against Dopamine Cytotoxicity Under High-Fat Diet?Induced Stress2020
- Author(s)
  Sakano Daisuke、Uefune Fumiya、Tokuma Hiraku、Sonoda Yuki、Matsuura Kumi、Takeda Naoki、Nakagata Naomi、Kume Kazuhiko、Shiraki Nobuaki、Kume Shoen
- Journal Title
  
  Diabetes
  
  Volume: 69 Issue: 11 Pages: 26-33
- DOI
  10.2337/db20-0207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08325, KAKENHI-PROJECT-18H02861, KAKENHI-PROJECT-18H02154
[Journal Article] Insulin2Q104del (Kuma) mutant mice develop diabetes with dominant inheritance2020
- Author(s)
  Sakano Daisuke、Inoue Airi、Enomoto Takayuki、Imasaka Mai、Okada Seiji、Yokota Mutsumi、Koike Masato、Araki Kimi、Kume Shoen
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 12187-12187
- DOI
  10.1038/s41598-020-68987-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07743, KAKENHI-PROJECT-20K08325, KAKENHI-PROJECT-18H02861, KAKENHI-PROJECT-16H06280
[Journal Article] Dopamine D2 receptor-mediated regulation of pancreatic b cell mass.2016
- Author(s)
  １.Sakano D, Choi S, Kataoka M, Shiraki N, Uesugi M, Kume K, Kume S
- Journal Title
  
  Stem Cell Reports
  
  Volume: ７ Issue: 1 Pages: 95-109
- DOI
  10.1016/j.stemcr.2016.05.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461036, KAKENHI-PROJECT-26461638, KAKENHI-PROJECT-16K01362, KAKENHI-PROJECT-26253059
[Journal Article] Pancreatic differentiation from murine embryonic stem cells. Methods Mol Biol.2016
- Author(s)
  Sakano D, Shiraki N, Kuem S
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1341 Pages: 417-423
- DOI
  10.1007/7651_2015_217
- ISBN
  9781493929535, 9781493929542
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461036, KAKENHI-PROJECT-26461638
[Journal Article] Beneficial effect of insulin treatment on islet transplantation outcomes in akita mice.2014
- Author(s)
  Kikawa K, Sakano D, Shiraki N, Tsuyama T, Kume K, Endo F, Kume S.
- Journal Title
  
  Plos one
  
  Volume: 9(4) Issue: 4 Pages: e95451-e95451
- DOI
  10.1371/journal.pone.0095451
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461036, KAKENHI-PROJECT-26461638, KAKENHI-PROJECT-26253059
[Journal Article] Generation of insulin-producing beta-like cells from human iPS cells in a defined and completely Xeno-free culture system.2014
- Author(s)
  Shahjalal HM, Shiraki N, Sakano D, Kikawa H, Ogaki S, Baba H, Kume K., Kume S.
- Journal Title
  
  Journal of Molecular Cell Biology
  
  Volume: 6 Issue: 5 Pages: 394-408
- DOI
  10.1093/jmcb/mju029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J01021, KAKENHI-PROJECT-26461036, KAKENHI-PROJECT-26461638, KAKENHI-PROJECT-26670384, KAKENHI-PROJECT-26253059
[Journal Article] VMAT2 identified as a regulator of late-stage beta cell differentiation2014
- Author(s)
  Sakano D , Shiraki N , Kikawa K , Yamazoe T, Kataoka M, Umeda K, Araki K, Mao D, Matsumoto S, Nakagata N, Andersson O, Stainier D, Endo F, Kume K, Uesugi M and Kume S
- Journal Title
  
  Nature Chem. Biol
  
  Volume: 10(2) Pages: 141-8
- NAID
  40020189460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790949
[Journal Article] VMAT2 identified as a regulator of late-stage beta cell differentiation.2013
- Author(s)
  Sakano, D., Shiraki, N., Kikawa, K., Yamazoe, T., Kataoka, M., Umeda, K., Araki, K., Mao, D., Matsumoto, S., Nakagata, N., Andersson, O., Stainier, D., Endo, F., Kume, K., Uesugi, M. and Kume, S.
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 10 Issue: 2 Pages: 141-148
- DOI
  10.1038/nchembio.1410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310135, KAKENHI-PUBLICLY-24115712, KAKENHI-PROJECT-24790949, KAKENHI-PROJECT-26461036, KAKENHI-PROJECT-26253059
[Patent] 幹細胞からインスリン産生細胞への分化誘導を促進する低分子化合物および該化合物を用いた幹細胞からインスリン産生細胞への分化誘導方法2010
- Inventor(s)
  粂昭苑、坂野大介、白木伸明、梅田香穂子、山添太士、粂和彦、上杉志成
- Industrial Property Rights Holder
  国立大学法人熊本大学、国立大学法人京都大学
- Filing Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] 膵β細胞におけるドーパミン生合成の役割とその制御機構の解明2023
- Author(s)
  板谷勇輝、上船史弥、徳間啓、富永成海、坂野大介、粂昭苑
- Organizer
  日本分子生物学会第45回年会
- Data Source
  KAKENHI-PROJECT-20K08325
[Presentation] ドパミンによる膵臓発生機構の解明2021
- Author(s)
  井上愛里、坂野大介、粂昭苑
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08325
[Presentation] 膵β細胞におけるD1-D2ヘテロ多量体を介したドーパミンによるインスリン分2021
- Author(s)
  上船史弥、坂野大介、粂昭苑
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08325
[Presentation] 膵β細胞の大量培養および成熟調節機構に関する研究2019
- Author(s)
  小野　満里絵、坂野大介、豊田　悠暉、荒木菜、、粂昭苑
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] Monoamine controls differentiation and maturation state of pancreatic β-cells2017
- Author(s)
  Yuki Toyoda, Sai Araki, Daisuke Sakano, Shoen Kume
- Organizer
  Conbio2017
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] モノアミンによるインスリン分泌制御機構の解明2017
- Author(s)
  上船史弥、園田雄輝、坂野大介、青西亨、粂昭苑
- Organizer
  50th Annual Meeting for the Japanese Society of Developmental Biologists
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] Generation and Characterization of an INSULIN promoter driven mCherry Reporter Human iPS Cell Lines Using CRISPR/Cas9 system2017
- Author(s)
  徳間　啓, Zixuan Erinn Sim, 上船　史弥, 坂野　大介, 白木　伸明, 粂　昭苑
- Organizer
  日本発生生物学会第50回大会
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] Establishment and analysis of hiPSC that visualize the INSULIN producing cells2017
- Author(s)
  徳間　啓, Zixuan Erinn Sim, 上船　史弥, 坂野　大介, 白木　伸明, 粂　昭苑
- Organizer
  第89回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] Signaling Pathway of Monoamine in Pancreatic β-cell Differentiation2017
- Author(s)
  Sai Araki, Yuki Toyoda, Daisuke Sakano, Shoen Kume
- Organizer
  Conbio2017
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] Analysis of Vmat2 mediated regulation in insulin secretion2017
- Author(s)
  Uefune F, Sonoda Y, Sakano D, Aonishi T, Kume S
- Organizer
  International Diabetes Federation Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] Monoamine signaling controls cell differentiation and maturation of pancreatic beta cell2017
- Author(s)
  Daisuke Sakano, Yuki Toyoda, Sai Araki, Nobuaki Shiraki, Shoen Kume
- Organizer
  Conbio2017
- Data Source
  KAKENHI-PROJECT-17K09455
[Presentation] モノアミンシグナルによる膵β細胞の分化・増殖制御、2016
- Author(s)
  坂野大介、崔　成翼、片岡正光、白木伸明、粂昭苑
- Organizer
  厚生労働省「ヒト幹細胞情報化推進事業」SKIP Seminar
- Place of Presentation
  東京都
- Invited
- Data Source
  KAKENHI-PROJECT-26461036
[Presentation] モノアミンシグナルによる膵β細胞の増殖・分化の制御2016
- Author(s)
  坂野大介、崔　成翼、片岡正光、白木伸明、粂昭苑
- Organizer
  日本生化学会
- Place of Presentation
  宮城県
- Data Source
  KAKENHI-PROJECT-26461036
[Presentation] モノアミンを介したシグナル伝達による膵島の構造・機能の制御2015
- Author(s)
  坂野大介
- Organizer
  第3回細胞凝集研究会
- Place of Presentation
  鹿児島
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26461036
[Presentation] VMAT2 identified as a regulator of late-stage pancreatic beta-cell differentiation,2013
- Author(s)
  Sakano D, Shiraki N, Kikawa K, Yamazoe T, Kataoka M, Umeda K, Araki K, Mao D, Matsumoto S, Nakagata N, Andersson O, Stainier D, Endo F, Kume K, Uesugi M, Kume S.
- Organizer
  ISSCR 11th Annual Meeting.
- Place of Presentation
  Boston Convention and Exhibition Center, Boston,USA
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] 化合物スクリーニングによる膵β細胞誘導法の効率化2013
- Author(s)
  坂野大介、白木伸明、片岡正光、木川和英、遠藤文夫、粂和彦、上杉志成、粂昭苑
- Organizer
  5拠点ミーティング
- Place of Presentation
  兵庫・有馬ホテル向陽閣
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] VMAT2 identified as a regulator of late-stage β-cell differentiation2013
- Author(s)
  Sakano D, Shiraki N, Kikawa K, Yamazoe T, Kataoka M, Umeda K, Araki K, Mao D, Matsumoto S, Nakagata N, Andersson O, Stainier D, Endo F, Kume K, Uesugi M and Kume S
- Organizer
  ISSCR 11th annual meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] Small compounds promote differentiation of functional insulin producing cells.2013
- Author(s)
  Sakano, D, Shiraki, N, Kikawa, K, Kataoka,M, Nagura, T, Choi, S, Endo F, Kume, K, Uesugi, M and Kume, S.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場, 兵庫
- Invited
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] SCREENING OF SMALL COMPOUNDS TO PROMOTE DIFFERENTIATION OF MOUSE ES CELLS TO FUNCTIONAL PANCREATIC β CELLS.2013
- Author(s)
  Sakano, D., Shiraki, N., Kikawa, K., Kataoka,M., Nagura, T., Choi, S., Endo F., Kume, K1, Uesugi, M. and Kume, S.
- Organizer
  ISSCR 11th Annual Meeting.
- Place of Presentation
  Boston・Boston Convention and Exhibition Center （USA)
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] Screening of low molecular compounds that promote differentiation of mouse ES cells to pancreatic β cells.2012
- Author(s)
  1. Sakano, D., Shiraki, N., Kataoka　M., Kikawa K., Endo F., M., Kume, K, Uesugi, M. and Kume, S.
- Organizer
  ISSCR 10th Annual Meeting.
- Place of Presentation
  神奈川・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] Screening of low molecular compounds that promote differentiation of mouse ES cells to pancreatic β cells.2012
- Author(s)
  坂野大介、白木伸明、片岡正光、木川和英、遠藤文夫、粂和彦、上杉志成、粂昭苑
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会
- Place of Presentation
  兵庫・神戸国際会議場、神戸商工会議所
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] 低分子化合物スクリーニングによる膵前駆細胞から内分泌前駆細胞への分化促進2012
- Author(s)
  坂野大介、白木伸明、木川和英、片岡正光、名倉岳志、崔成翼、遠藤文夫、粂和彦、上杉志成、粂昭苑
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡・福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] A novel chemical screening system for understanding of pancreatic β-cell differentiation from mouse ES cells.2012
- Author(s)
  2. Sakano、 D.、 Shiraki、 N.、 Kataoka、 Kikawa K.、 Endo F.、 M.、 Kume、 K、 Uesugi、 M. and Kume、 S.
- Organizer
  第10回幹細胞シンポジウム
- Place of Presentation
  兵庫・淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] A neonatal mouse model of pancreatic beta-cell regeneration after destruction by streptozotocin2012
- Author(s)
  2. Kataoka　M.,Kawamuro Y., Miki R., Sakano, D., Shiraki, N., Yoshida T.,Kume K. and Kume, S.
- Organizer
  ISSCR 10th Annual Meeting.
- Place of Presentation
  神奈川・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] Small compounds promote differentiation from pancreatic progenitor to endocrine cells MBSJ2012
- Author(s)
  Sakano D, Shiraki N, Kikawa K, Kataoka M, Nagura T, Choi S, Endo F, Kume K, Uesugi M and Kume S
- Organizer
  MBSJ
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-24790949
[Presentation] Low molecular compounds screening system for β cell inducing activity2011
- Author(s)
  Sakano D., Shiraki N., Kataoka M., Kume K., Kume S.
- Organizer
  The workshop "Liver and Pancreas : From Development to Disease"
- Place of Presentation
  Baeza, Spain
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] The establishment of a screening system for low molecular compounds forβcell inducing activity2011
- Author(s)
  Sakano D., Shiraki N., Kataoka M., Kume K. and Kume S.
- Organizer
  International Society for Stem Cell Resaerch 9^<th> Annual Meeting
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] Low molecular compounds screening system forβcell inducing activity2011
- Author(s)
  Sakano D., Shiraki N., Kataoka M., Kume K. and Kume S.
- Organizer
  The workshop "Liver and Pancreas : From Development to Disease"
- Place of Presentation
  Baeza, Spain
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] The establishment of a screening system for low molecular compounds for β cell inducing activity2011
- Author(s)
  Sakano D., Shiraki N., Kataoka M., Kume K., Kume S.
- Organizer
  International Society for Stem Cell Research 9^<th> Annual Meeting
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] The establishment of a screening system for low molecular compoumds for β cell inducing activity2010
- Author(s)
  坂野大介
- Organizer
  2010 Global COE-IMEG Joint Summer Retreat Seminar
- Place of Presentation
  ホテルグリーンピア南阿蘇(熊本)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] The establishment of a screening system for low moleculaz compounds for β cell inducing activity2010
- Author(s)
  坂野大介
- Organizer
  分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] The establishment of a screening system for low molecular compounds forβcell inducing activity2010
- Author(s)
  Sakano, D., Shiraki, N., Kataoka, M., Kume, K and Kume, S.
- Organizer
  The 33rd Annual Meeting of Molecular Biology Society of Japan, The 83rd Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-22790653
[Presentation] 膵β細胞の複製を促進する低分子化合物の探索
- Author(s)
  坂野大介、崔成翼、片岡正光、粂昭苑
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26461036

1. 荒木正健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 荒木喜美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 小池正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 粂昭苑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKANO Daisuke 坂野 大介

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Co-Researchers

Elucidation of the functional regulatory mechanism of pancreatic islets via monoamine signalingPrincipal Investigator

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Elucidation of monoamine-GPCR signal-regulated pancreatic beta cell differentiation and maturation mechanismPrincipal Investigator

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Elucidation of pancreatic beta cell differentiation and maturation mechanism by monoaminesPrincipal Investigator

Principal Investigator

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Small compounds promote differentiation of functional insulin producing cellsPrincipal Investigator

Principal Investigator

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The establishment of a screening system for low molecular compounds forβcell inducing activity.Principal Investigator

Principal Investigator

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[Book] 「膵β細胞再生療法の最前線」『糖尿病・内分泌代謝科』2020

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[Book] 糖尿病学20202020

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[Book] 「膵β細胞・膵島の再生研究」『特集 糖尿病-診断・治療update-』2014

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[Book] 「膵島バイオロジーの新たな展開」『幹細胞を用いた膵β細胞誘導研究』、Diabetes Frontier2014

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[Book] 「膵β細胞研究の進化と展望」 『多能性幹細胞から膵β細胞への分化を制御するシグナル』Islet Equality2014

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[Book] 「糖尿病と代謝」『iPS細胞を用いた膵β細胞研究の最前線』、Diabetes Journal2014

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[Book] 『発生・分化・再生と代謝関連臓器」「多能性幹細胞から膵 β 細胞への分化」 『内分泌・糖尿病・代謝内科』24(5)2013

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[Book] 内分泌・糖尿病・代謝内科 特集 発生・分化・再生と代謝関連臓器 多能性幹細胞から膵β 細胞への分化, 第35巻第2号2012

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[Book] 内分泌・糖尿病・代謝内科 特集 発生・分化・再生と代謝関連臓器 多能性幹細胞から膵β細胞への分化、2012

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[Book] 「iPS細胞による糖尿病医療研究のこれから」-The view of stem cell therapy for type I diabetes-糖尿病2011

Author(s)

Publisher

SAKANO Daisuke 坂野大介

[Book] 「膵β細胞・膵島の再生研究」『特集　糖尿病-診断・治療update-』2014

[Book] 「膵β細胞研究の進化と展望」『多能性幹細胞から膵β細胞への分化を制御するシグナル』Islet Equality2014

[Book] 『発生・分化・再生と代謝関連臓器」「多能性幹細胞から膵 β 細胞への分化」『内分泌・糖尿病・代謝内科』24(5)2013

[Book] 内分泌・糖尿病・代謝内科特集発生・分化・再生と代謝関連臓器多能性幹細胞から膵β 細胞への分化, 第35巻第2号2012

[Book] 内分泌・糖尿病・代謝内科　特集　発生・分化・再生と代謝関連臓器　多能性幹細胞から膵β細胞への分化、2012