okabe hirohisa 岡部弘尚

… Alternative Names

OKABE Hirohisa 岡部弘尚

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Researcher Number	40573621
Other IDs	https://orcid.org/0000-0003-4943-4523
Affiliation (Current)	2025: 熊本大学, 病院, 助教
Affiliation (based on the past Project Information) *help	2024: 熊本大学, 病院, 助教 2022: 熊本大学, 大学院生命科学研究部(医), 特定研究員 2019 – 2021: 熊本大学, 病院, 非常勤診療医師 2017 – 2018: 熊本大学, 医学部附属病院, 助教 2015 – 2016: 熊本大学, 医学部附属病院, 非常勤診療医師 … More 2015: 熊本大学, その他の研究科, 医員 2014: 熊本大学, 医学部附属病院, 助手 2014: 熊本大学, 医学部附属病院, 診療助手 2014: 熊本大学, 医学部附属病院, 特任助教 2011 – 2013: 熊本大学, 医学部附属病院, 非常勤診療医師 2012: 熊本大学, 医学部附属病院, その他 Less
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator TAN / 肝外胆管癌 / CD8 T細胞 / 制御性T細胞 / 腫瘍関連好中球 / 腫瘍関連マクロファージ / 肝細胞癌 / 好中球 / 線維芽細胞 / 肝内胆管癌 … More / 癌関連線維芽細胞 / 組織消化 / myofibroblast / 肝星細胞 / 胆管癌 / CAF（癌関連線維芽細胞） … More Except Principal Investigator 膵癌 / 転移 / 胆管癌 / PD-L1 / CXCL12 / 肝内胆管癌 / 浸潤 / 癌間質細胞 / 補体C5a / C5a受容体 / DZNep / アポトーシス / 細胞周期 / EZH2 / 肝細胞癌 / バイオマーカー / 予後 / Molecular gene signature / 腫瘍微小環境 / 腫瘍免疫 / PD-1 / 免疫チェックポイント / マクロファージ / TNF-α / Vivo / 予後不良 / vivo / 免疫化学組織染色 / cDNAマイクロアレイ / ＴＧＦ / 抗がん剤抵抗性 / EMT / TGF-beta / TAZ / YAP / C5a / 癌転移 / 癌浸潤 / 膵星細胞 / CAF / 線維芽細胞 / 胃接合部癌 / CXCR4 / 胃癌 / 癌関連線維芽細胞（CAF） / Angiogenesis / Notch1 / 細胞増殖 / 血管新生 / VASH1 / 肝星細胞 / ヒト肝星細胞 / Farnesoid受容体X / 胆汁酸 / FXR / 肝切除 / 肝再生 / FXR agonist / ポリコーム蛋白 / gemcitabine / Cholangiocarcinoma / Zeste Homolog 2 / 3-deazaneplanocin A / p27KIP1 / p16INK4A / apoptosis / cell cycle / epigenetics / cholangiocarcinoma / Enhancer / 上皮間葉形質転換 / CD44＋CD90＋細胞 / 血中癌細胞（CTC） / 血中癌幹細胞 / CD45-CD44+CD90+細胞 / Anoikis / CD44 / 上皮間葉形質転換 (EMT) / 血中癌細胞 Less

Gene signatureによる膵癌化学療法の治療効果予測及び新規治療標的の検証
- Principal Investigator
  
  中川茂樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
The significance and the mechanism of PD-L1 expression in the tumor microenvironment for novel therapeutic agents
- Principal Investigator
  
  Tsukamoto Masayo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Impact of PD-L1/PD-1 crosstalk on cancer cell in pancreatic ductal carcinoma
- Principal Investigator
  
  Imai Katsunori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Analysis of the interaction between pancreatic stromal cells and adenocarcinoma via complement component 5a receptor
- Principal Investigator
  
  TAKAMORI Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Signal crosstalk between TGF-beta and Hippo-pathway in pancreatic
- Principal Investigator
  
  CHIKAMOTO Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
The mechanism of promoting liver metastasis caused by CXCL 12 and fundamental research for innovative therapeutic development in intrahepatic cholangiocarcinoma
- Principal Investigator
  
  MASUDA Tosirou
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
The role of tumor-associated neutrophil in the progression of hepatocellular carcinoma.Principal Investigator
- Principal Investigator
  
  OKABE Hirohisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Analysis of tumor-stromal interaction via complement C5a receptor in cancer microenvironment
- Principal Investigator
  
  NAKAHARA Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Drug screening for cholangiocarcinoma targeting the epigenetical mechanism of cancer progression
- Principal Investigator
  
  CHIKAMOTO Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Therapeutic implication for cancer-associated fibroblasts (CAF) in cholangiocarcinoma
- Principal Investigator
  
  IMAI Katsunori
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Clinical implication of Farnesoid-X-receptor agonist in liver regeneration after hepatectomy
- Principal Investigator
  
  TAKAMORI Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Characterization of circulating tumor cells and its application of the treatment selection for hepatocellular carcinoma
- Principal Investigator
  
  BEPPU toru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
The role of polycomb protein expression and application for epigenetic therapy in cholangiocarcinoma.
- Principal Investigator
  
  CHIKAMOTO Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
The isolation and characterization of cancer associated fibroblasts for clinical therapeutic application.Principal Investigator
- Principal Investigator
  
  OKABE Hirohisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Prognostic Value of the Preoperative Tumor Marker Index in Resected Pancreatic Ductal Adenocarcinoma: A Retrospective Single-Institution Study2020
- Author(s)
  Miyata Tatsunori、Hayashi Hiromitsu、Yamashita Yo-ichi、Matsumura Kazuki、Nakao Yosuke、Itoyama Rumi、Yamao Takanobu、Tsukamoto Masayo、Okabe Hirohisa、Imai Katsunori、Chikamoto Akira、Ishiko Takatoshi、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 28 Issue: 3 Pages: 1572-1580
- DOI
  10.1245/s10434-020-09022-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16418, KAKENHI-PROJECT-18K08651
[Journal Article] Varied application of intercostal trans-diaphragmatic ports for laparoscopic hepatectomy2020
- Author(s)
  Hayashi Hiromitsu、Yamashita Yo-ichi、Okabe Hirohisa、Imai Katsunori、Higashi Takaaki、Yamamura Kensuke、Chikamoto Akira、Beppu Toru、Takamori Hiroshi、Baba Hideo
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 6 Pages: e0234919-e0234919
- DOI
  10.1371/journal.pone.0234919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07777, KAKENHI-PROJECT-18K08623
[Journal Article] Frailty Predicts Severe Postoperative Complication after Elective Hepatic Resection2019
- Author(s)
  Okabe Hirohisa、Hayashi Hiromitsu、Higashi Takaaki、Nitta Hidetoshi、Ikuta Yoshiaki、Yusa Toshihiko、Takeyama Hideaki、Ogawa Katsuhiro、Ozaki Nobuyuki、Akahoshi Shinichi、Ogata Kenichi、Osaki Takayuki、Baba Hideo、Takamori Hiroshi
- Journal Title
  
  Gastrointestinal Tumors
  
  Volume: 6 Issue: 1-2 Pages: 28-35
- DOI
  10.1159/000500086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08623
[Journal Article] 膵全摘術：一期的手術と二期的手術2019
- Author(s)
  岡部弘尚、山下洋市、林洋光、北村文優、上村紀雄、宮田辰徳、中川茂樹、今井克憲、近本亮、馬場秀夫
- Journal Title
  
  胆と膵
  
  Volume: 第40巻1号 Pages: 57-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19936
[Journal Article] Frailty predicts severe postoperative complications after elective colorectal surgery2019
- Author(s)
  Okabe Hirohisa、Ohsaki Takayuki、Ogawa Katsuhiro、Ozaki Nobuyuki、Hayashi Hiromitsu、Akahoshi Shinichi、Ikuta Yoshiaki、Ogata Kenichi、Baba Hideo、Takamori Hiroshi
- Journal Title
  
  The American Journal of Surgery
  
  Volume: 217 Issue: 4 Pages: 677-681
- DOI
  10.1016/j.amjsurg.2018.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08623, KAKENHI-PROJECT-16K19936
[Journal Article] Histological architectural classification determines recurrence pattern and prognosis after curative hepatectomy in patients with hepatocellular carcinoma2018
- Author(s)
  Okabe Hirohisa、Yoshizumi Tomoharu、Yamashita Yo-ichi、Imai Katsunori、Hayashi Hiromitsu、Nakagawa Shigeki、Itoh Shinji、Harimoto Norifumi、Ikegami Toru、Uchiyama Hideaki、Beppu Toru、Aishima Shinichi、Shirabe Ken、Baba Hideo、Maehara Yoshihiko
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 9 Pages: e0203856-e0203856
- DOI
  10.1371/journal.pone.0203856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10670, KAKENHI-PROJECT-16K19936
[Journal Article] 十二指腸球後部潰瘍膵頭部穿破による膵周囲膿瘍の1例2018
- Author(s)
  岡部弘尚、遊佐俊彦、林洋光、生田義明、馬場秀夫、髙森啓史
- Journal Title
  
  日本臨床外科学会誌
  
  Volume: 第79巻4号 Pages: 763-769
- NAID
  130007502333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19936
[Journal Article] Tumor-infiltrating inflammatory and immune cells in patients with extrahepatic cholangiocarcinoma.2018
- Author(s)
  Kitano Y, Okabe H, Yamashita YI, Nakagawa S, Saito Y, Umezaki N, Tsukamoto M, Yamao T, Yamamura K, Arima K, Kaida T, Miyata T, Mima K, Imai K, Hashimoto D, Komohara Y, Chikamoto A, Ishiko T, Baba H
- Journal Title
  
  Br J Cancer
  
  Volume: 118(2) Issue: 2 Pages: 171-180
- DOI
  10.1038/bjc.2017.401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19936, KAKENHI-PROJECT-18K16369, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-17K16570
[Journal Article] Clinical significance of half-lives of tumor markers α-fetoprotein and des-γ-carboxy prothrombin after hepatectomy for hepatocellular carcinoma.2018
- Author(s)
  Tsukamoto M, Nitta H, Imai K, Higashi T, Nakagawa S, Okabe H, Arima K, Kaida T, Taki K, Hashimoto D, Chikamoto A, Ishiko T, Beppu T, Baba H
- Journal Title
  
  Hepatol Res.
  
  Volume: 48 Issue: 3
- DOI
  10.1111/hepr.12942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10503, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-15K10171
[Journal Article] Downregulation of 15-hydroxyprostaglandin dehydrogenase by interleukin-1β from activated macrophages leads to poor prognosis in pancreatic cancer.2018
- Author(s)
  Arima K, Komohara Y, Bu L, Tsukamoto M, Itoyama R, Miyake K, Uchihara T, Ogata Y, Nakagawa S, Okabe H, Imai K, Hashimoto D, Chikamoto A, Yamashita YI, Baba H, Ishimoto T
- Journal Title
  
  Cancer Sci
  
  Volume: 109(2) Issue: 2 Pages: 462-470
- DOI
  10.1111/cas.13467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19936, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K15595
[Journal Article] Shape and enhancement characteristics of pancreatic neuroendocrine tumor on preoperative contrast-enhanced computed tomography may be prognostic indicators.2017
- Author(s)
  Okabe H, Hashimoto D, Chikamoto A, Morikatsu Y, Taki K, Arima K, Imai K,Tamura Y, Ikeda O, Ishiko T, Uchiyama H, Ikegami T, Harimoto N, Itoh S, Yamashita Y, Yoshizumi T, Beppu T, Yamashita Y, Baba H, Maehara Y.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 24(5) Issue: 5 Pages: 1399-1405
- DOI
  10.1245/s10434-016-5630-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K10285, KAKENHI-PROJECT-16K10604, KAKENHI-PROJECT-16K19936
[Journal Article] Neutrophil-to-lymphocyte ratio predicts metachronous liver metastasis of pancreatic neuroendocrine tumors.2017
- Author(s)
  Arima K, Okabe H, Hashimoto D, Chikamoto A, Nitta H, Higashi T, Kaida T, Yamamura K, Kitano Y, Komohara Y, Yamashita Y, Beppu T, Takeya M, Baba H.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: in press Issue: 4 Pages: 734-739
- DOI
  10.1007/s10147-017-1111-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Survival impact of lymphocyte infiltration into the tumor of hepatocellular carcinoma in hepatitis B virus-positive or non-B non-C patients who underwent curative resection.2017
- Author(s)
  Nakagawa S, Umezaki N, Yamao T, Kaida T, Okabe H, Mima K, Imai K, Hashimoto D, Yamashita YI, Ishiko T, Chikamoto A, Baba H
- Journal Title
  
  Hepatol Res.
  
  Volume: 48(3) Issue: 3
- DOI
  10.1111/hepr.12936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19936
[Journal Article] Pre-treatment double- or triple-positive tumor markers are predictive of a poor outcome for patients undergoing radiofrequency ablation for hepatocellular carcinoma.2017
- Author(s)
  itta H, Nakagawa S, Kaida T, Arima K, Higashi T, Taki K, Okabe H, Hayashi H, Hashimoto D, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Surg Today
  
  Volume: 47(3) Issue: 3 Pages: 375-384
- DOI
  10.1007/s00595-016-1385-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K10503, KAKENHI-PROJECT-15K10171
[Journal Article] Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice.2016
- Author(s)
  Okabe H, Yang J, Sylakowski K, Yovchev M, Miyagawa Y, Nagarajan S, Chikina M, Thompson M, Oertel M, Baba H, Monga SP, Nejak-Bowen KN.
- Journal Title
  
  Hepatology
  
  Volume: 64(5) Issue: 5 Pages: 1652-1666
- DOI
  10.1002/hep.28774
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Diverse basis of β-catenin activation in human hepatocellular carcinoma: Implications in biology and prognosis.2016
- Author(s)
  Okabe H, Kinoshita H, Imai K, Nakagawa S, Higashi T, Arima K, Uchiyama H, Ikegami T, Harimoto N, Itoh S, Ishiko T, Yoshizumi T, Beppu T, Monga SP, Baba H and Maehara Y.
- Journal Title
  
  PLoS One
  
  Volume: 11(4) Issue: 4 Pages: e0152695-e0152695
- DOI
  10.1371/journal.pone.0152695
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] A case report of bacteremia manifesting as an overwhelming postsplenectomy infection due to Streptococcus pneumoniae post vaccination.2016
- Author(s)
  Hirose K, Okabe H, Yoshizumi T, Uchiyama H, Ikegami T, Harimoto N, Itoh S, Kimura K, Baba H, Maehara Y.
- Journal Title
  
  Surg Case Rep
  
  Volume: 2(1) Issue: 1 Pages: 48-48
- DOI
  10.1186/s40792-016-0173-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Preoperative platelet-to-lymphocyte ratio can predict recurrence beyond the Milan criteria after hepatectomy for patients with hepatocellular carcinoma.2016
- Author(s)
  Kaida T, Nitta H, Kitano Y, Yamamura K, Arima K, Higashi T, Taki K, Nakagawa S, Okabe H, Hayashi H, Imai K, Hashimoto D, Yamashita YI, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Hepatol Res
  
  Volume: Epub ahead of print Issue: 10 Pages: 991-999
- DOI
  10.1111/hepr.12835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K10503, KAKENHI-PROJECT-15K10171
[Journal Article] Portal Vein Embolization Followed by Right-Side Hemihepatectomy for Hepatocellular Carcinoma Patients: A Japanese Multi-Institutional Study.2016
- Author(s)
  Beppu T, Okabe H, Okuda K, Eguchi S, Kitahara K, Taniai N, Ueno S, Shirabe K, Ohta M, Kondo K, Nanashima A, Noritomi T, Okamoto K, Kikuchi K, Baba H, FujiokaH.
- Journal Title
  
  J Am Coll Surg.
  
  Volume: 222 Issue: 6 Pages: 1138-1148
- DOI
  10.1016/j.jamcollsurg.2016.03.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Salvage splenic artery embolization for saving falling living donor graft due to portal overflow.2016
- Author(s)
  Okabe H, Yoshizumi T, Ikegami T, Uchiyama H, Harimoto N, Itoh S, Kimura K, Baba H, Maehara Y.
- Journal Title
  
  Transplant Proc
  
  Volume: 48(9) Issue: 9 Pages: 3171-3173
- DOI
  10.1016/j.transproceed.2016.07.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Inducible factors for cancer-associated fibroblasts in liver cancer versus myofibroblasts in inflammatory liver disease.2016
- Author(s)
  Okabe H, Hayashi H, Nakagawa S, Imai K, Nitta H, Arima K, Hashimoto D, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Histol Histopathol
  
  Volume: 31(2) Pages: 141-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19936
[Journal Article] The diagnostic role of the neutrophil-to-lymphocyte ratio in predicting pancreatic ductal adenocarcinoma in patients with pancreatic diseases.2016
- Author(s)
  Arima K, Okabe H, Hashimoto D, Chikamoto A, Tsuji A, Yamamura K, Kitano Y, Inoue R, Kaida T, Higashi T, Taki K, Imai K, Komohara Y, Beppu T, Takeya M, Baba H.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 21(5) Issue: 5 Pages: 940-945
- DOI
  10.1007/s10147-016-0975-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma.2016
- Author(s)
  Higashi T, Hayashi H, Kitano Y, Yamamura K, Kaida T, Arima K, Taki K, Nakagawa S, Okabe H, Nitta H, Imai K, Hashimoto D, Chikamoto A, Beppu T, Baba H.
- Journal Title
  
  Med Oncol.
  
  Volume: 33(11) Issue: 11 Pages: 123-123
- DOI
  10.1007/s12032-016-0845-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-16K19939, KAKENHI-PROJECT-16K19940
[Journal Article] A long survivor with local relapse of hilar cholangiocarcinoma after R1 surgery treated with chemoradiotherapy: a case report and literature review.2016
- Author(s)
  Okabe H, Chikamoto A, Maruno M, Hashimoto D, Imai K, Taki K, Arima K, Ishiko T, Uchiyama H, Ikegami T, Harimoto N, Itoh S, Yoshizumi T, Beppu T, Baba H, Maehara Y.
- Journal Title
  
  Surg Case Rep
  
  Volume: 2(1) Issue: 1 Pages: 69-69
- DOI
  10.1186/s40792-016-0195-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-16K19936
[Journal Article] Inducible factors for cancer-associated fibroblasts in liver cancer versus myofibroblasts in inflammatory liver disease.2016
- Author(s)
  Okabe H, Hayashi H, Nakagawa S, Imai K, Nitta H, Arima K, Hashimoto D, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Histol Histopathol
  
  Volume: 31(2) Pages: 141-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047
[Journal Article] Significance of P-cadherin overexpression and possible mechanism of its regulation in intrahepatic cholangiocarcinoma and pancreatic cancer.2015
- Author(s)
  Sakamoto K, Imai K, Higashi T, Taki K, Nakagawa S, Okabe H, Nitta H, Hayashi H, Chikamoto A, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Cancer Sci
  
  Volume: 106(9) Issue: 9 Pages: 1153-62
- DOI
  10.1111/cas.12732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-26462045
[Journal Article] Scoring system based on tumor markers and Child-Pugh classification for HCC patients who underwent liver resection.2015
- Author(s)
  Nakagawa S, Hayashi H, Nitta H, Okabe H, Sakamoto K, Higashi T, Kuroki H, Imai K, Hashimoto D, Sakamoto Y, Chikamoto A, Beppu T, Baba H.
- Journal Title
  
  Anticancer Res
  
  Volume: 35(4) Pages: 2157-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10191
[Journal Article] Complete response of Ctnnb1-mutated tumours to β-catenin suppression by locked nucleic acid antisense in a mouse hepatocarcinogenesis model2015
- Author(s)
  Delgado E, Okabe H, Preziosi M, Russell JO, Alvarado TF, Oertel M, Nejak-Bowen KN, Zhang Y, Monga SP
- Journal Title
  
  J Hepatol
  
  Volume: 62 Issue: 2 Pages: 380-7
- DOI
  10.1016/j.jhep.2014.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462047
[Journal Article] Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma2014
- Author(s)
  Okabe H, Delgado E, Lee JM, Yang J, Kinoshita H, Hayashi H, Tsung A, Behari J, Beppu T, Baba H, Monga SP
- Journal Title
  
  PLOS ONE
  
  Volume: 9(6) Issue: 6 Pages: e98817-e98817
- DOI
  10.1371/journal.pone.0098817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592008
[Journal Article] EZH2 Is Associated with Malignant Behavior in Pancreatic IPMN via p27Kip1 Downregulation2014
- Author(s)
  Kuroki H, Hayashi H, Okabe H, Hashimoto D, Takamori H, Nakahara O, Nakagawa S, Fukushima Y, Chikamoto A, Beppu T, Hirota M, Iyama K, Baba H
- Journal Title
  
  PLOS ONE
  
  Volume: 9(8) Issue: 8 Pages: e100904-e100904
- DOI
  10.1371/journal.pone.0100904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592033, KAKENHI-PROJECT-24592034, KAKENHI-PROJECT-26462047
[Journal Article] Rank classification based on the combination of indocyanine green retention rate at 15 min and (99m)Tc-DTPA-galactosyl human serum albumin scintigraphy predicts the safety of hepatic resection2014
- Author(s)
  Okabe H, Beppu T, Hayashi H, Masuda T, Mima K, Nakagawa S, Kuroki H, Imai K, Nitta H, Masuda T, Hashimoto D, Chikamoto A, Wanatanabe M, Ishiko T, Yoshida M, Yamashita Y, Baba H.
- Journal Title
  
  Nucl Med Commun
  
  Volume: 35 Issue: 5 Pages: 478-483
- DOI
  10.1097/mnm.0000000000000075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-26462047
[Journal Article] Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells.2014
- Author(s)
  Nakagawa S, Sakamoto Y, Okabe H, Hayashi H, Hashimoto D, Yokoyama N, Tokunaga R, Sakamoto K, Kuroki H, Mima K, Beppu T, Baba H.
- Journal Title
  
  Oncology Report
  
  Volume: 31 Issue: 2 Pages: 983-8
- DOI
  10.3892/or.2013.2922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24592033
[Journal Article] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation2014
- Author(s)
  Ishimoto T, Sugihara H, Watanabe M, Sawayama H, Iwatsuki M, Baba Y, Okabe H, Hidaka K, Yokoyama N, Miyake K, Yoshikawa M, Nagano O, Komohara Y, Takeya M, Saya H, Baba H.
- Journal Title
  
  Carcinogenesis
  
  Volume: 35(5) Issue: 5 Pages: 1003-11
- DOI
  10.1093/carcin/bgt402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-26293290
[Journal Article] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation.2014
- Author(s)
  Ishimoto T, Sugihara H, Watanabe M, Sawayama H, Iwatsuki M, Baba Y, Okabe H, Hidaka K, Yokoyama N, Miyake K, Yoshikawa M, Nagano O, Komohara Y, Takeya M, Saya H, Baba H.
- Journal Title
  
  Carcinogenesis
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549
[Journal Article] Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma2014
- Author(s)
  Okabe H, Delgado E, Lee JM, Yang J, Kinoshita H, Hayashi H, Tsung A, Behari J, Beppu T, Baba H, Monga SP.
- Journal Title
  
  Plos One
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549
[Journal Article] Beta-catenin signaling in murine liver zonation and regeneration : A Wnt-Wnt situation!2014
- Author(s)
  Yang J, Nejak-Bowen KN, Okabe H, Lang RA, Williams RO, Monga SP.
- Journal Title
  
  Hepatology 2014
  
  Volume: (in press) Issue: 3 Pages: 964-976
- DOI
  10.1002/hep.27082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549
[Journal Article] CD44s signals the acquisition of the mesenchymal phenotype required for anchorage-independent cell survival in hepatocellular carcinoma.2014
- Author(s)
  Okabe H, Ishimoto T, Mima K, Nakagawa S, Hayashi H, Kuroki H, Imai K, Nitta H, Saito S, Hashimoto D, Chikamoto A, Ishiko T, Watanabe M, Nagano O, Beppu T, Saya H and Baba H
- Journal Title
  
  Br J Cancer
  
  Volume: 印刷中 Issue: 4 Pages: 958-66
- DOI
  10.1038/bjc.2013.759
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24590389, KAKENHI-PROJECT-24592008
[Journal Article] Triple positive tumor markers predict recurrence and survival in early stage hepatocellular carcinoma2014
- Author(s)
  Nakagawa S, Beppu T, Okabe H, Sakamoto K, Kuroki H, Mima K, Nitta H, Imai K, Hayashi H, Sakamoto Y, Hashimoto D, Chikamoto A, Ishiko T, Watanabe M, Baba H
- Journal Title
  
  Hepatol Res
  
  Volume: 44(9) Issue: 9 Pages: 964-74
- DOI
  10.1111/hepr.12277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592033, KAKENHI-PROJECT-26460867
[Journal Article] CYLD down-regulation might berelated to tumor development in HCCpatients.2013
- Author(s)
  Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Yokoyama N, Ishiko T,Shinriki S, Jono H, Ando Y, Baba H
- Journal Title
  
  Mol Clin Oncol 1
  
  Volume: 1 Issue: 2 Pages: 309-314
- DOI
  10.3892/mco.2013.68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-24592008
[Journal Article] Enhancer of Zeste Homolog 2 (EZH2) Promotes Progression of Cholangiocarcinoma Cells by Regulating Cell Cycle and Apoptosis.2013
- Author(s)
  Nakagawa S, Okabe H, Sakamoto Y, Hayashi H, Hashimoto D, Yokoyama N, Sakamoto K, Kuroki H, Mima K, Nitta H, Imai K, Chikamoto A, Watanabe M, Beppu T, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 3 Issue: S3 Pages: 667-675
- DOI
  10.1245/s10434-013-3135-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592008, KAKENHI-PROJECT-24592033, KAKENHI-PROJECT-25462099, KAKENHI-PROJECT-15K10191
[Journal Article] CYLD downregulation is correlated with tumor development in patients with hepatocellular carcinoma2013
- Author(s)
  Kinoshita H, Okabe H, Beppu T, Chikamoto A, Hayashi H, Imai K, Mima K, Nakagawa S, Yokoyama N, Ishiko T, Shinriki S, Jono H, Ando Y, Baba H.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 1 Pages: 309-314
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24649166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549
[Journal Article] Remnant liver volume-based predictors of postoperative liver dysfunction after hepatectomy : Analysis of 625 consecutive patients from a single institution2013
- Author(s)
  Okabe H, Beppu T, Chikamoto A, Hayashi H, Yoshida M, Masuda T, Imai K, Mima K, Nakagawa S, Kuroki H, Nitta H, Hashimoto D, Ishiko T, Yamashita Y, Baba H.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: (Epub ahead of print) Issue: 4 Pages: 614-21
- DOI
  10.1007/s10147-013-0591-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-26460867
[Journal Article] Epithelial-mesenchymal transition expression profiles as prognostic factor for disease-free survival in hepatocellular carcinoma: clinical significance of transforming growth factor-β signaling.2013
- Author(s)
  Mima K, Hayashi H, Kuroki H, Nakagawa S, Okabe H, Chikamoto A, Watanabe M, Beppu T, Baba H.
- Journal Title
  
  Oncol Lett
  
  Volume: 5 Pages: 149-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592008
[Journal Article] Mima K, Hayashi H, Kuroki H, NakagawaS, Okabe H, Chikamoto A, Watanabe M,Beppu T, Baba H2013
- Author(s)
  Mima K, Hayashi H, Kuroki H, NakagawaS, Okabe H, Chikamoto A, Watanabe M,Beppu T, Baba H
- Journal Title
  
  Oncology Lett
  
  Volume: 5 Issue: 1 Pages: 149-154
- DOI
  10.3892/ol.2012.954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549
[Journal Article] High CD44s expression is associatedwith the EMT expression profile andintrahepatic dissemination ofhepatocellular carcinoma after localablation therapy.2013
- Author(s)
  Mima K, Hayashi H,Imai K, Kuroki H,Shigaki N, Nakagawa S, Okabe H,Chikamoto A, Watanabe M, Beppu T, BabaH
- Journal Title
  
  J Hepatobiliary Pancreatic Surg
  
  Volume: 20 Issue: 4 Pages: 429-34
- DOI
  10.1007/s00534-012-0580-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24592008
[Journal Article] Percentage of future liver remnant volume before portal vein embolization influences the degree of liver regeneration after hepatectomy. J Gastrointest Surg2013
- Author(s)
  Okabe H, Beppu T, Nakagawa S, Yoshida M, Hayashi H, Masuda T, Imai K, Mima K, Kuroki H, Nitta H, Hashimoto D, Chikamoto A, Ishiko T, Watanabe M, Yamashita Y, Baba H.
- Journal Title
  
  J Gastrointest Surg
  
  Volume: 17(8) Issue: 8 Pages: 1447-51
- DOI
  10.1007/s11605-013-2237-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24791434
[Journal Article] Combined measurements of serum bileacid level and splenic volume may beuseful to noninvasively assess theportal venous pressure.2012
- Author(s)
  Hayashi H, Beppu T, Kuroki H, NakagawaS, Mima K, Okabe H, Nitta H, Imai K,Chikamoto A, Baba H
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Issue: 12 Pages: 1336-1341
- DOI
  10.1007/s00535-012-0599-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-23890164
[Journal Article] External biliary drainage and liver regeneration after major hepatectomy.2012
- Author(s)
  太田尾　龍、岡部　弘尚、他
- Journal Title
  
  British Journal of Surgery
  
  Volume: 99 Issue: 11 Pages: 1569-1574
- DOI
  10.1002/bjs.8906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24791434
[Journal Article] Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Ishimoto T, Miyake K,Yokoyama N, Ishiko T, Baba2012
- Author(s)
  Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Ishimoto T, Miyake K,Yokoyama N, Ishiko T, Baba
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Issue: 2 Pages: 685-9
- DOI
  10.3892/or.2012.2162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24592008
[Journal Article] Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts2012
- Author(s)
  Hirohisa Okabe
- Journal Title
  
  International Journal of Cancer
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549
[Journal Article] CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer.2012
- Author(s)
  Saito S, Miyamoto Y, et al.
- Journal Title
  
  Oncol Rep.
  
  Volume: 29 Issue: 4 Pages: 1570-8
- DOI
  10.3892/or.2013.2273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591966, KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-25670588
[Journal Article] CD44s regulates the TGF-β-mediatedmesenchymal phenotype and isassociated with poor prognosis inpatients with hepatocellularcarcinoma.2012
- Author(s)
  Mima K, Okabe H, Ishimoto T, HayashiH, Nakagawwa S, Kuroki H, Watanabe M
- Journal Title
  
  Cancer Res
  
  Volume: 72 Issue: 13 Pages: 3414-23
- DOI
  10.1158/0008-5472.can-12-0299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549
[Journal Article] Upregulation of ERCC1 and DPDexpressions after oxaliplatin-basedfirst-line chemotherapy formetastatic colorectal cancer2012
- Author(s)
  Baba H,Watanabe M, Okabe H, Miyamoto Y,Sakamoto Y, Baba Y, Iwatsuki M,Chikamoto A, Beppu T.
- Journal Title
  
  Br J Cancer
  
  Volume: 107 Issue: 12 Pages: 1950-5
- DOI
  10.1038/bjc.2012.502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659656, KAKENHI-PROJECT-23791549
[Journal Article] Identification of CXCL5/ENA-78 as afactor involved in the interactionbetween cholangiocarcinoma cells andcancer-associated fibroblasts.2012
- Author(s)
  Okabe H, Beppu T, Ueda M, Hayashi H,Ishiko T, Masuda T, Otao R, Horlad H,Mima K, Miyake K, Iwatsuki M, Baba Y,Takamori H, Jono H, Shinriki S, AndoY, Baba H
- Journal Title
  
  Int J Cancer 131
  
  Volume: in press Issue: 10 Pages: 2234-41
- DOI
  10.1002/ijc.27496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23790091, KAKENHI-PROJECT-23791549
[Journal Article] Hepatic stellate cells acceleratethe malignant behavior ofcholangiocarcinoma.2011
- Author(s)
  DOI:10.5772/51793kabe H, Beppu T, Hayashi H, Ishiko T,Masuda T, Otao R, Shinriki S, HorladH, Jono H, Ueda M, Ando Y, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18 Issue: 4 Pages: 1175-84
- DOI
  10.1245/s10434-010-1391-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549
[Journal Article] The role of hepatic stellate cells in the pathogenesis of hepatocellular and cholangiocarcinoma2011
- Author(s)
  Okabe H, Beppu T, Hayashi H, Ishiko T, Masuda T, Otao R, Horlad H, Baba H.
- Journal Title
  
  Europ J Clin Med Oncol 2011
  
  Volume: 3: (2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791549
[Journal Article] Preoperative portal veinembolization (PVE) for patients withhepatocellular carcinoma can improveresectability and may improvedisease-free survival2011
- Author(s)
  Okabe H, Beppu T, Ishiko T, Masuda T,Hasyashi H, Otao R, Hasta H, Okabe K,Sugiyama S, Baba H
- Journal Title
  
  J Surg Oncol
  
  Volume: 104 Issue: 6 Pages: 641-6
- DOI
  10.1002/jso.21928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23650544, KAKENHI-PROJECT-23791549
[Presentation] 腫瘍微小環境における炎症性シグナルを介した膵癌進展メカニズムの解明2018
- Author(s)
  有馬浩太、伊東山瑠美、石本崇胤、三宅慧輔、内原智幸、中川茂樹、岡部弘尚、林洋光、今井克憲、近本亮、山下洋市、馬場秀夫
- Organizer
  第29回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18K08651
[Presentation] 膵神経内分泌腫瘍におけるCT画像所見による悪性度予測の有用性2018
- Author(s)
  岡部弘尚、山下洋市、松本嵩史、伊東山瑠美、遊佐俊彦、中尾陽佑、北野雄希、中川茂樹、今井克憲、新田英利、近本亮、馬場秀夫
- Organizer
  JDDW 2018
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 自動縫合器による膵切離における術後膵液ろうに関わる因子の検討2018
- Author(s)
  岡部弘尚、山下洋市、北村文優、上村紀雄、中尾陽佑、遊佐俊彦、伊東山瑠美、中川茂樹、今井克憲、林洋光、近本亮、馬場秀夫
- Organizer
  第31回日本内視鏡外科学会総会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] Clinical impact of non-alcoholic fatty liver disease in patients after curative surgery with pancreatic cancer2018
- Author(s)
  Hirohisa Okabe、Yo-ichi Yamashita, Shotaro Kinoshita, Rumi Itoyama, Toshihiko Yusa, Yuki Kitano, Yosuke Nakao, Shigeki Nakagawa, Katsunori Imai, Hidetoshi Nitta, Akira Chikamoto, Hideo Baba
- Organizer
  第64回国際外科学会日本部会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] The impact of portal invasion on oncological outcome after pancreatic surgery with curative intent in patients with pancreatic cancer2018
- Author(s)
  Hirohisa Okabe、Yo-ichi Yamashita, Toshihiko Yusa, Rumi Itoyama, Yosuke Nakao, Yuki Kitano, Shigeki Nakagawa, Katsunori Imai, Hidetoshi Nitta, Akira Chikamoto, Hideo Baba
- Organizer
  第30回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 腹部手術歴を有する例に対する鏡視下肝切除の問題点と胸腔を活用したアプローチの工夫2018
- Author(s)
  林　洋光、高森啓史、山下洋市、生田義明、増田稔郎、岡部弘尚、中川茂樹、今井克憲、近本亮、馬場秀夫
- Organizer
  第31回日本内視鏡外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08709
[Presentation] 膵癌におけるKRAS statusに基づいた臨床的な腫瘍特性と抗癌剤耐性との関連性についての検討2018
- Author(s)
  岡部弘尚、山下洋市、伊東山瑠美、北野雄希、中川茂樹、今井克憲、新田英利、近本亮、馬場祥史、馬場秀夫
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 膵腸吻合におけるModified Blumgart法の短期成績2018
- Author(s)
  岡部弘尚、山下洋市、北村文優、上村紀雄、宮田辰徳、中川茂樹、今井克憲、林洋光、近本亮、馬場秀夫
- Organizer
  第45回日本膵切研究会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 膵腸吻合におけるModified Blumgart法の短期成績2018
- Author(s)
  岡部弘尚、山下洋市、湯本信成、森戸淳、上村紀雄、宮田辰徳、中川茂樹、今井克憲、林洋光、近本亮、馬場秀夫
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 膵頭十二指腸切除におけるModified Blumgart法による膵腸吻合の短期成績2018
- Author(s)
  岡部弘尚、山下洋市、近本亮、松本嵩史、遊佐俊彦、中尾陽佑、伊東山瑠美、北野雄希、中川茂樹、新田英利、今井克憲、馬場秀夫
- Organizer
  第72回手術手技研究会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] Assessment and validation of functional liver resection rate considering venous occlusive area after extended hepatectomy.2018
- Author(s)
  Hidetoshi Nitta, Toshihiko Yusa, Yosuke Nakao, Rumi Itoyama, Yuki Kitano, Shigeki Nakagawa, Hirohisa Okabe, Katsunori Imai, Yo-ichi Yamashita, Akira Chikamoto, Hideo Baba.
- Organizer
  The 30th Meeting of Japanese Society of Hepato-Biliary Pancreatic Surgery.
- Data Source
  KAKENHI-PROJECT-18K08623
[Presentation] Borderline resectable膵癌に対する術前化学療法の有用性に関する臨床病理学的検討2018
- Author(s)
  岡部弘尚、山下洋市、北村文優、上村紀雄、宮田辰徳、中川茂樹、今井克憲、林洋光、近本亮、馬場秀夫
- Organizer
  第13回膵癌術前治療研究会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] Borderline resectable 膵癌根治切除例の予後および臨床病理学的検討2018
- Author(s)
  岡部弘尚、山下洋市、橋本大輔、堀之内誠、中尾陽佑、遊佐俊彦、伊東山瑠美、北野雄希、中川茂樹、今井克憲、近本亮、馬場秀夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] Borderline resectable膵癌に対する術前化学療法の治療成績2018
- Author(s)
  岡部弘尚、山下洋市、北村文優、上村紀雄、中尾陽佑、遊佐俊彦、伊東山瑠美、北野雄希、中川茂樹、今井克憲、近本亮、馬場秀夫
- Organizer
  第80回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 膵NETにおけるCT画像所見の臨床的意義2018
- Author(s)
  岡部弘尚、山下洋市、松本嵩史、伊東山瑠美、遊佐俊彦、中尾陽佑、北野雄希、中川茂樹、今井克憲、新田英利、近本　亮、馬場秀夫
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 胆管癌R1切除例に対する治療効果に関する検討2018
- Author(s)
  岡部弘尚、山下洋市、北野雄希、湯本信成、森戸淳、上村紀雄、宮田辰徳、中川茂樹、今井克憲、林洋光、近本亮、馬場秀夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 膵体尾部切除における、自動縫合器を用いた膵切離における術後膵液瘻に関わる因子の検討2018
- Author(s)
  岡部弘尚、山下洋市、北村文優、上村紀雄、宮田辰徳、中川茂樹、今井克憲、林洋光、近本亮、馬場秀夫
- Organizer
  第10回膵臓内視鏡外科研究会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 癒着性腸閉塞に対する腹腔鏡下手術の有用性と課題2017
- Author(s)
  岡部弘尚、赤星慎一、遊佐俊彦、武山秀晶、小川克大、林　洋光、尾崎宣之、生田義明、緒方健一、高森啓史
- Organizer
  第54回九州外科学会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] Clinicalfrailtyscoreは結腸直腸癌手術の短期成績予測に有用である2017
- Author(s)
  岡部弘尚、小川克大、緒方健一、赤星慎一、尾﨑宣之、生田義明、林洋光、武山秀晶、遊佐俊彦、高森啓史
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] Frailty, but not sarcopenia, predicts severe postoperative complication after hepatectomy2017
- Author(s)
  Hirohisa Okabe、Hiromitsu Hayashi, Toshihiko Yusa, Hideaki Takeyama, Katsuhiro Ogawa, Nobuyuki Ozaki, Shinichi Akahoshi, Yoshiaki Ikuta, Kenichi Ogata, Hiroshi Takamori
- Organizer
  第6回アジア太平洋肝胆膵学会・第29回日本肝胆膵外科学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] フレイルは結腸直腸癌手術後合併症発生の危険因子で，術後回復促進の負の要因となる2017
- Author(s)
  岡部弘尚、小川克大、遊佐俊彦、武山秀晶、林洋　光、尾﨑宣之、赤星慎一、生田義明、緒方健一、高森啓史
- Organizer
  第72回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 化学療法後手術を施行したBR/UR膵癌症例の治療成績に関する臨床病理学的検討2017
- Author(s)
  岡部弘尚、髙森啓史、山下洋市、生田義明、橋本大輔、近本　亮、林　洋光、今井克憲、中川茂樹、馬場秀夫
- Organizer
  第12回膵癌術前治療研究会
- Data Source
  KAKENHI-PROJECT-16K19936
[Presentation] 肝細胞癌の発育進展と間葉系形質獲得からみた原発性肝癌取り扱い規約の組織構造分類の意義2016
- Author(s)
  岡部弘尚、調　憲、吉住朋晴、内山秀昭、池上徹、播本憲史、伊藤心二、木村光一、馬場秀夫、前原喜彦
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-26462047
[Presentation] 肝細胞癌切除後再発に対して局所凝固療法を行った症例における予後規定因子の探索2016
- Author(s)
  岡部弘尚、山下洋市、今井克憲、甲斐田剛圭、石河隆敏、馬場秀夫
- Organizer
  第35回Microwave Surgery研究会
- Place of Presentation
  メルパルク熊本（熊本県）
- Data Source
  KAKENHI-PROJECT-26462047
[Presentation] 肝細胞癌の再発形式・生存予後に関与する，組織構造分類の新たな提言2016
- Author(s)
  岡部弘尚、調　憲、吉住朋晴、内山秀昭、池上徹、播本憲史、伊藤心二、木村光一、馬場秀夫、前原喜彦
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  アスティとくしま（徳島県）
- Data Source
  KAKENHI-PROJECT-26462047
[Presentation] Enhancer of zeste homolog 2 (EZH2) promotes progression of cholangiocarcinoma by regulating cell cycle and apoptosis2013
- Author(s)
  Shigeki Nakagawa, Hirohisa Okabe, Yasuo Sakamoto, Hiromitsu Hayashi, Daisuke Hashimoto, Hideyuki Kuroki, Katsunori Imai, Hidetoshi Nitta, Akira Chikamoto, Masayuki Watanabe, Toru Beppu, Hideo Baba
- Organizer
  American Association of Cancer Research2013
- Place of Presentation
  アメリカ・ワシントン
- Data Source
  KAKENHI-PROJECT-24592033
[Presentation] 肝内胆管癌の癌間質相互作用におけるCXCL5の役割2012
- Author(s)
  岡部　弘尚
- Organizer
  日本外科学会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23791549
[Presentation] Identification of CXCL5/ENA-78 regulating the interaction of cholangiocarcinoma and cancer-associated fibroblasts2012
- Author(s)
  岡部　弘尚、他
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23791549
[Presentation] Identification of CXCL5/ENA-78 regulating the interaction of cholangiocarcinoma and cancer-associated fibroblasts2012
- Author(s)
  Okabe H, Beppu T, Ueda M, Hayashi H, Masuda T, Mima K, Nakagawa S, Miyake K, Yokoyama N, Baba Y, Takamori H, Ishiko T, Jono H, Shinriki S, Ando Y, Baba H.
- Organizer
  AACR103th Annual Meeting 2012
- Place of Presentation
  Chicago convention center, IL, USA
- Data Source
  KAKENHI-PROJECT-23791549
[Presentation] 肝内胆管癌の癌間質相互作用におけるCXCL5の役割2012
- Author(s)
  岡部弘尚、別府透、植田光晴、石河隆敏、近本亮、美馬浩介、中川茂樹、今井克憲、城野博史、高森啓史、安東由喜雄、馬場秀夫
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉(幕張メッセ国際会議場)
- Year and Date
  2012-04-12
- Data Source
  KAKENHI-PROJECT-23791549
[Presentation] 質量分析を用いた癌関連線維芽細胞と胆管癌細胞の相互作用を制御する因子CXCLの同定2011
- Author(s)
  岡部弘尚、別府透、植田光晴、石河隆敏、近本亮、増田稔郎、ハスタホスラッド、美馬浩介、城野博史、高森啓史、安東由喜男、馬場秀夫
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-23791549
[Presentation] Side population cells have some stem-like properties in hepatocellular carcinoma2011
- Author(s)
  OkabeH, Beppu T, Ishiko T, Chikamoto A, Masuda T, Otao R, Hasita H, Mima K, Takamori H, Baba H.
- Organizer
  AACR102nd Annual Meeting 2011
- Place of Presentation
  Orland convention center, FL, USA.
- Year and Date
  2011-04-02
- Data Source
  KAKENHI-PROJECT-23791549
[Presentation] 切除不能肝細胞癌follow up中の門脈侵襲出現に関する検討
- Author(s)
  岡部和利
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-24592008

1. IMAI Katsunori (60555746)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. 林洋光 (80625773)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
3. 中川茂樹 (10594872)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. BEPPU toru (70301372)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. CHIKAMOTO Akira (10419640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. 橋本大輔 (80508507)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. TAKAMORI Hiroshi (90363514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 新田英利 (90555749)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. 山下洋市 (00404070)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. ANDO Yukio (20253742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAHARA Osamu (40583042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MASUDA Tosirou (50551256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. Tsukamoto Masayo (30836268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 美馬浩介 (00546559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
15. 日比泰造 (10338072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山尾宣暢 (70836337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 北野雄希 (40814760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 伊東山瑠美 (50868172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MIYAMOTO yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. YAMAMURA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 渡邊雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 馬場秀夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 宮田辰徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 佐谷秀行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

okabe hirohisa 岡部 弘尚

OKABE Hirohisa 岡部 弘尚

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The role of tumor-associated neutrophil in the progression of hepatocellular carcinoma.Principal Investigator

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The isolation and characterization of cancer associated fibroblasts for clinical therapeutic application.Principal Investigator

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[Journal Article] Prognostic Value of the Preoperative Tumor Marker Index in Resected Pancreatic Ductal Adenocarcinoma: A Retrospective Single-Institution Study2020

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okabe hirohisa 岡部弘尚

OKABE Hirohisa 岡部弘尚