Hirotsu Naoki 廣津直樹

… Alternative Names

HIROTSU Naoki 廣津直樹

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Researcher Number	40584389
Other IDs	https://orcid.org/0000-0002-9893-7111
Affiliation (Current)	2025: 東洋大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 東洋大学, 生命科学部, 教授 2017 – 2018: 東洋大学, 生命科学部, 教授 2010 – 2016: 東洋大学, 生命科学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 38040:Bioorganic chemistry-related / Crop production science / Science in genetics and breeding / Crop science/Weed science Except Principal Investigator Environmental impact assessment/Environmental policy
Keywords	Principal Investigator イネ / インドール酢酸 / ショ糖リン酸合成酵素(SPS) / 染色体断片置換系統 / 創薬 / 玄米 / フラグメントスクリーニング / フィチン酸 / 粒重 / 基質認識 … More / サーマルシフトアッセイ / X線結晶構造解析 / タンパク質結晶化 / リコンビナントタンパク質 / アンタゴニスト / 収量 / 炭水化物蓄積 / 代謝 / ソース能 / デンプン / 登熟 / デンプン蓄積 / オーキシン / 窒素吸収速度 / 乾物生産 / 初期生育 / ショ糖リン酸合成酵素 / 窒素吸収 / 成長解析 / 量的形質遺伝子座 / FACE / ショ糖リン酸シンターゼ / 開放系大気CO_2増加(FACE) … More Except Principal Investigator 毒性 / 銀ナノコロイド / メダカ / 動物プランクトン / 藻類 / 水生植物 / 活性汚泥 / 生態リスク評価 / 個体群理論 / 銀ナノ粒子 / 生態毒性 / 生態系影響評価 / ナノマテリアル Less

Development of phytic acid biosynthetic enzyme inhibitors to reduce the phytic acid content of rice grain.Principal Investigator
- Principal Investigator
  
  廣津直樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Toyo University
Designing of TGW6 antagonist toward improving grain size in rice.Principal Investigator
- Principal Investigator
  
  Hirotsu Naoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Toyo University
The Effect of Loss of TGW6 on Starch Accumulation and Toranslocation in RicePrincipal Investigator
- Principal Investigator
  
  Hirotsu Naoki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Crop production science
- Research Institution
  Toyo University
Physiological characterization of quantitative trait loci involving for biomass production in ricePrincipal Investigator
- Principal Investigator
  
  Hirotsu Naoki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Science in genetics and breeding
- Research Institution
  Toyo University
Aquatic ecological risk assessments of silver nanocolloids based on population growth analyses
- Principal Investigator
  
  KASHIWADA Shosaku
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental impact assessment/Environmental policy
- Research Institution
  Toyo University
The effects of changes in sucrose-phosphate synthase gene expression to the biomass production in rice.Principal Investigator
- Principal Investigator
  
  HIROTSU Naoki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Crop science/Weed science
- Research Institution
  Toyo University

All 2024 2023 2022 2021 2020 2018 2017 2015 2014 2013 2011 Other

All Journal Article Presentation Book

[Book] Chapter 10: Improving bioavailability of zinc in rice grains by reducing antinutrients through genetic engineering2023
- Author(s)
  Ishara Perera, Naoki Hirotsu
- Total Pages
  11
- Publisher
  Academic Press, Elsevier
- ISBN
  9780323854061
- Data Source
  KAKENHI-PROJECT-23K05066
[Journal Article] THOUSAND-GRAIN WEIGHT 6, which is an IAA-glucose hydrolase, preferentially recognizes the structure of the indole ring2024
- Author(s)
  Tatsuki Akabane, Nobuhiro Suzuki, Kazuyoshi Ikeda, Tomoki Yonezawa, Satoru Nagatoishi, Hiroyoshi Matsumura, Takuya Yoshizawa, Wataru Tsuchiya, Satoshi Kamino, Kouhei Tsumoto, Ken Ishimaru, Etsuko Katoh and Naoki Hirotsu
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 6778-6778
- DOI
  10.1038/s41598-024-57506-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1979, KAKENHI-PROJECT-23K05066
[Journal Article] イネの収量および栄養価を向上させる創薬2023
- Author(s)
  赤羽根健生、廣津直樹、加藤悦子
- Journal Title
  
  アグリバイオ
  
  Volume: 7 Pages: 88-91
- Data Source
  KAKENHI-PROJECT-20K05869
[Journal Article] Expression, purification and crystallization of TGW6, which limits grain weight in rice2021
- Author(s)
  Akabane Tatsuki、Suzuki Nobuhiro、Tsuchiya Wataru、Yoshizawa Takuya、Matsumura Hiroyoshi、Hirotsu Naoki、Katoh Etsuko
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 188 Pages: 105975-105975
- DOI
  10.1016/j.pep.2021.105975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05869
[Journal Article] イネの収量エンハンサーの創薬に向けて2020
- Author(s)
  廣津直樹
- Journal Title
  
  アグリバイオ
  
  Volume: 4 Pages: 76-79
- NAID
  40022337828
- Data Source
  KAKENHI-PROJECT-20K05869
[Journal Article] Partial loss-of-function of NAL1 alters canopy photosynthesis by changing the contribution of upper and lower canopy leaves in rice.2018
- Author(s)
  Naoki Hirotsu, Kazuhiro Ujiie, Ishara Perera, Ayano Iri, Takayuki Kashiwagi & Ken Ishimaru.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 15958-15958
- DOI
  10.1038/s41598-017-15886-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14840, KAKENHI-PROJECT-17K07631
[Journal Article] Comparative analysis of N-glycans in the ungerminated and germinated stages of Oryza sativa.2015
- Author(s)
  Risa Horiuchi, Naoki Hirotsu and Nobumitsu Miyanishi.
- Journal Title
  
  Carbohydrate Research
  
  Volume: 418 Pages: 1-8
- DOI
  10.1016/j.carres.2015.09.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25870780, KAKENHI-PROJECT-26790026
[Journal Article] Loss of function of the IAA-glucose hydrolase gene TGW6 enhances rice grain weight and increases yield.2013
- Author(s)
  Ken Ishimaru, Naoki Hirotsu, Yuka Madoka, Naomi Murakami, Nao Hara, Haruko Onodera, Takayuki Kashiwagi, Kazuhiro Ujiie, Bun-ichi Shimizu, Atsuko Onishi, Hisashi Miyagawa & Etsuko Katoh.
- Journal Title
  
  Nature Genetics
  
  Volume: 45 Issue: 6 Pages: 707-711
- DOI
  10.1038/ng.2612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870780
[Journal Article] New insight into photosynthetic acclimation to elevated CO_2 : The role of leaf nitrogen and ribulose-1,5-bisphosphate carboxylase/oxygenase in rice leaves2011
- Author(s)
  Seneweera S, Makino A, Hirotsu N, Norton R, Suzuki Y
- Journal Title
  
  Environ. Exp. Bot
  
  Volume: 71 Issue: 2 Pages: 128-136
- DOI
  10.1016/j.envexpbot.2010.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21114006, KAKENHI-PROJECT-22780055, KAKENHI-PROJECT-22880036, KAKENHI-PROJECT-23380040
[Journal Article] New insight into photosynthetic acclimation to elevated CO_2 : The role of leaf nitrogen and ribulose-1 5-bisphosphate carboxylase/oxygenase content in rice.2011
- Author(s)
  Seneweera S., Makino A., Hirotsu N., Norton R., Suzuki Y.
- Journal Title
  
  Environmental and Experimental Botany
  
  Volume: 71巻2号 Pages: 128-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22880036
[Presentation] イネのフィチン酸含量を低減させるINO1アンタゴニストの開発を目指した薬剤探索2024
- Author(s)
  赤羽根健生、神野智司、池田和由、米澤朋起、加藤悦子、廣津直樹
- Organizer
  第65回日本植物生理学会年会
- Data Source
  KAKENHI-PROJECT-23K05066
[Presentation] イネのミネラル利用効率を向上させるINO1アンタゴニストの開発を目指した薬剤探索2023
- Author(s)
  赤羽根健生、廣津直樹、神野智司、加藤悦子
- Organizer
  第64回日本植物生理学会年会
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] イネの粒重を制御するTGW6の阻害剤候補の選抜と作物科学的評価2023
- Author(s)
  赤羽根健生、市川円香、加藤悦子、廣津直樹
- Organizer
  日本作物学会第255回講演会
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] イネ粒重を抑制する TGW6 の阻害剤開発を目指した19F NMR フラグメントスクリーニング2022
- Author(s)
  赤羽根健生、長門石曉、津本浩平、廣津直樹、加藤悦子
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] イネの粒重を抑制するTGW6のX線結晶構造解析2022
- Author(s)
  赤羽根健生、鈴木喜大、土屋渉、吉澤拓也、松村浩由、加藤悦子、廣津直樹
- Organizer
  2021年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] イネの穀粒サイズを抑制するTGW6の立体構造解析2022
- Author(s)
  赤羽根健生、鈴木喜大、土屋渉、吉澤拓也、松村浩由、加藤悦子、廣津直樹
- Organizer
  第63回日本植物生理学会年会
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] イネの粒重を抑制するTGW6とそのホモログの立体構造比較2022
- Author(s)
  赤羽根健生、鈴木喜大、土屋渉、吉澤拓也、松村浩由、加藤悦子、廣津直樹
- Organizer
  第253回日本作物学会講演会
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] The purification of recombinant TGW6, which limits the grain size2021
- Author(s)
  Tatsuki Akabane, Nobuhiro Suzuki, Wataru Tsuchiya, Etsuko Katoh, Naoki Hirotsu
- Organizer
  10th Asian Crop Science Association Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] イネ穀粒サイズを抑制するTGW6のリコンビナントタンパク質の結晶化2021
- Author(s)
  赤羽根健生、土屋渉、鈴木喜大、加藤悦子、廣津直樹
- Organizer
  第 62 回植物生理学会年会
- Data Source
  KAKENHI-PROJECT-20K05869
[Presentation] 機能喪失型TGW6によるデンプン転流の変化と登熟障害耐性への影響2018
- Author(s)
  野口雅弘、清水順平、杉崎文哉、石丸健、廣津直樹
- Organizer
  第245回日本作物学会講演会
- Data Source
  KAKENHI-PROJECT-16K14840
[Presentation] The Effect of IAA Inhibitor on Starch Accumulation in Rice Leaves2018
- Author(s)
  Kawawa S, Ishimaru K, Hirotsu N.
- Organizer
  5th International Rice Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14840
[Presentation] Effect of loss of TGW6 on starch translocation and grain filling2018
- Author(s)
  Noguchi M, Shimizu J, Sugisaki F, Ishimaru K, Hirotsu N.
- Organizer
  5th International Rice Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14840
[Presentation] 機能喪失型TGW6における葉へのデンプン蓄積メカニズムの解析2017
- Author(s)
  川和信一郎, 石丸健, 廣津直樹
- Organizer
  第244回日本作物学会講演会
- Data Source
  KAKENHI-PROJECT-16K14840
[Presentation] イネの初期生育速度に関与する要因の生理学的解析2014
- Author(s)
  永井雄基、砂川裕貴、望月麻衣、廣津直樹
- Organizer
  日本植物生理学会
- Place of Presentation
  富山大学（富山）
- Data Source
  KAKENHI-PROJECT-25870780
[Presentation] The genetic control of rice yield through gleaning superior genes.2013
- Author(s)
  Naoki Hirotsu
- Organizer
  7th International Rice Genetics Symposium.
- Place of Presentation
  Manila, Philippine
- Invited
- Data Source
  KAKENHI-PROJECT-25870780
[Presentation] 「藍藻類及び原生動物に対する銀ナノコロイド曝露における影響」2013
- Author(s)
  金沢彩子、長坂征治、仲亀雄哉、有吉理、片岡千里、竹井弘之、廣津直樹、岩見徳雄、杉浦則夫、内海真生、柏田祥策、清水和哉
- Organizer
  日本環境毒性学会
- Place of Presentation
  東洋大学（東京）
- Data Source
  KAKENHI-PROJECT-23310026
[Presentation] SNCs はイネの根に酸化ストレスを引き起こす2013
- Author(s)
  眞島芽衣・根岸理紗・神山翔伍・平野俊・廣津直樹
- Organizer
  第54回日本植物生理学会年会,PF160
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23310026
[Presentation] 藍藻類及び原生動物に対するSNCs 曝露における影響2013
- Author(s)
  金沢彩子, 長坂征治, 仲亀雄哉, 有吉理, 片岡千里, 竹井弘之, 廣津直樹, 岩見徳雄, 杉浦則夫, 内海真生, 柏田祥策, 清水和哉
- Organizer
  第19回日本環境毒性学会研究発表会
- Place of Presentation
  東洋大学(東京)
- Data Source
  KAKENHI-PROJECT-23310026
[Presentation] カサラス型OsSPS1 をもつ染色体断片置換系統イネの生育およびガス交換速度の解析2013
- Author(s)
  永井雄基、廣津直樹
- Organizer
  日本作物学会
- Place of Presentation
  鹿児島大学（鹿児島）
- Data Source
  KAKENHI-PROJECT-25870780
[Presentation] 開放系大気CO_2濃度増加(FACE)が染色体断片置換イネのバイオマス生産に及ぼす影響2011
- Author(s)
  廣津直樹・根岸理紗・氏家和広・常田岳志・酒井英光・中村浩史・長谷川利拡・石丸健
- Organizer
  日本作物学会第231回講演会
- Place of Presentation
  東京農業大学農学部
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22880036
[Presentation] 開放系大気CO2濃度増加(FACE)が染色体断片置換イネのバイオマス生産に及ぼす影響2011
- Author(s)
  廣津直樹, (他7名)
- Organizer
  日本作物学会第231回講演会
- Place of Presentation
  厚木市において発表予定であったが、震災のため講演会中止となり、要旨のみ発表(中止)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22880036
[Presentation] コメ種子由来レクチンの特性解析
- Author(s)
  遠坂翼、堀内里紗、廣津直樹、宮西伸光
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学（名古屋市）
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-25870780
[Presentation] The genetic control of rice yield using novel genes.
- Author(s)
  Naoki Hirotsu
- Organizer
  2nd Ruhuna International Science & Technology Conference
- Place of Presentation
  University of Ruhuna, Matara, Sri Lanka
- Year and Date
  2015-01-22 – 2015-01-23
- Invited
- Data Source
  KAKENHI-PROJECT-25870780
[Presentation] 銀ナノコロイドはイネの根に酸化ストレスを引き起こす
- Author(s)
  眞島芽衣・根岸理紗・神山翔伍・平野俊・廣津直樹
- Organizer
  第54回日本植物生理学会年会
- Place of Presentation
  岡山大学
- Data Source
  KAKENHI-PROJECT-23310026
[Presentation] イネの生長時における糖鎖構造の挙動
- Author(s)
  堀内里紗、遠坂翼、廣津直樹、宮西伸光
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学（名古屋市）
- Year and Date
  2014-08-11 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-25870780
[Presentation] 機能欠失型TGW6のソース器官における機能と高温登熟障害回避へ果たす役割
- Author(s)
  竹村ほづみ、清水順平、氏家和広、石丸健、廣津直樹
- Organizer
  日本作物学会第239回講演会
- Place of Presentation
  日本大学湘南キャンパス（神奈川県藤沢市）
- Year and Date
  2015-03-27 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25870780

1. 加藤悦子 (00355752)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. KASHIWADA Shosaku (20370265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. TATSUTA Haruki (50370268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGASAKA Seiji (60534013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. SAKAMOTO Masaki (20580070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIMIZU Kazuya (10581613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. TAKEI Hiroyuki (40520789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KATSUMATA Masakazu (80394005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 長谷川輝明 (90423566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木雄二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 牧野周

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirotsu Naoki 廣津 直樹

HIROTSU Naoki 廣津 直樹

Research Projects

Research Products

Co-Researchers

Development of phytic acid biosynthetic enzyme inhibitors to reduce the phytic acid content of rice grain.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Designing of TGW6 antagonist toward improving grain size in rice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Effect of Loss of TGW6 on Starch Accumulation and Toranslocation in RicePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological characterization of quantitative trait loci involving for biomass production in ricePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Aquatic ecological risk assessments of silver nanocolloids based on population growth analyses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effects of changes in sucrose-phosphate synthase gene expression to the biomass production in rice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Chapter 10: Improving bioavailability of zinc in rice grains by reducing antinutrients through genetic engineering2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] THOUSAND-GRAIN WEIGHT 6, which is an IAA-glucose hydrolase, preferentially recognizes the structure of the indole ring2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] イネの収量および栄養価を向上させる創薬2023

Author(s)

Journal Title

Data Source

[Journal Article] Expression, purification and crystallization of TGW6, which limits grain weight in rice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] イネの収量エンハンサーの創薬に向けて2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Partial loss-of-function of NAL1 alters canopy photosynthesis by changing the contribution of upper and lower canopy leaves in rice.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparative analysis of N-glycans in the ungerminated and germinated stages of Oryza sativa.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loss of function of the IAA-glucose hydrolase gene TGW6 enhances rice grain weight and increases yield.2013

Author(s)

Journal Title

DOI

Hirotsu Naoki 廣津直樹

HIROTSU Naoki 廣津直樹