Numata Keiji 沼田圭司

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NUMATA Keiji 沼田圭司

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Researcher Number	40584529
Other IDs
Affiliation (Current)	2025: 京都大学, 工学研究科, 教授 2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2020 – 2025: 京都大学, 工学研究科, 教授 2015: 国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー 2013 – 2014: 独立行政法人理化学研究所, 環境資源科学研究センター, チームリーダー 2012: 独立行政法人理化学研究所, 酵素研究チーム, チームリーダー 2011: 独立行政法人理化学研究所, 酵素研究チーム, 上級研究員
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (II) / Basic Section 27040:Biofunction and bioprocess engineering-related / Medium-sized Section 35:Polymers, organic materials, and related fields / Transformative Research Areas, Section (III) / Green/Environmental chemistry / Polymer/Textile materials Except Principal Investigator Transformative Research Areas, Section (III) / Broad Section E
Keywords	Principal Investigator シルク / 生分解性ポリエステル / 高分子精密分解 / 環境毒性 / 細胞毒性 / オリゴマー / 生分解性高分子 / ペプチド / ナノキャリア / タンパク質導入 … More / 遺伝子送達 / ミトコンドリア / 高分子の生分解 / 高分子の精密分解 / ペクチン / 高分子材料 / ベータシート構造 / ゲル / サンゴ / ネットワーク構造 / 癌細胞 / 遺伝子デリバリー … More Except Principal Investigator ゲノム編集 / 細胞内共生 / ミトコンドリアゲノム / 葉緑体ゲノム / オルガネラゲノム / オルガネラ / ミトコンドリア / 葉緑体 / 細胞質ゲノム / 遺伝子発現 / 熱安定性予測 / エネルギーデータベース / 細胞内環境 / 核酸構造 Less

クモ牽引糸タンパク質の分子機構を明らかにし、クモ糸の階層構造を人工的に再現するPrincipal Investigator
- Principal Investigator
  
  沼田圭司
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 35:Polymers, organic materials, and related fields
- Research Institution
  Kyoto University
ヒトへの遺伝子導入の為の自己組織化高分子ペプチドシステムのバイオミメティクス製作Principal Investigator
- Principal Investigator
  
  沼田圭司
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kyoto University
Genomic regulation of intracellular symbiotic organelles: from technological innovation to understanding and application of life phenomena
- Principal Investigator
  
  有村慎一
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
オルガネラへの核酸および生理活性分子導入Principal Investigator
- Principal Investigator
  
  沼田圭司
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Quantitative prediction of nucleic acid structures and functions affected by spaciotemporal environmental factors in cells
- Principal Investigator
  
  杉本直己
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section E
- Research Institution
  Konan University
Precision Degradation of Polymer and Polymeric MaterialArea Organizer
- Area Organizer
  
  沼田圭司
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
Polymer characterization platform for precise polymer degradationsPrincipal Investigator
- Principal Investigator
  
  Numata Keiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Kyoto University
Precise characterizations of degradation products and assessment of their impact on the biological environmentsPrincipal Investigator
- Principal Investigator
  
  Numata Keiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Kyoto University
Plant cell wall-mimicking silk-pectin hydrogel for coral reef regenerationPrincipal Investigator
- Principal Investigator
  
  Numata Keiji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Green/Environmental chemistry
- Research Institution
  Institute of Physical and Chemical Research
Gene carriers containing functional peptides for breast cancer treatmentPrincipal Investigator
- Principal Investigator
  
  NUMATA Keiji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Polymer/Textile materials
- Research Institution
  The Institute of Physical and Chemical Research

All 2025 2024 2023 2022 2021 2020 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] Engineering peptide-based carriers for drug and gene delivery.2014
- Author(s)
  Jo-Ann Chuah, David Kaplan, Keiji Numata
- Publisher
  Engineering in Translational Medicine.Springer, London. (受理済み)
- Data Source
  KAKENHI-PROJECT-23750264
[Book] Silk Biomaterials in Tissue Engineering and Regenerative Medicine2013
- Author(s)
  Keiji Numata
- Total Pages
  16
- Publisher
  Woodhead Publishing
- Data Source
  KAKENHI-PROJECT-25810110
[Journal Article] Synthesis of cyclic peptide-based [2]rotaxanes <i>via</i> copper-catalyzed azide?alkyne cycloaddition2025
- Author(s)
  Kurita Taichi、Numata Keiji
- Journal Title
  
  Polymer Chemistry
  
  Volume: 16 Issue: 4 Pages: 409-414
- DOI
  10.1039/d4py01169d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PROJECT-23KJ1250
[Journal Article] Chemoenzymatic Polymerization/Depolymerization of Semiaromatic Polyamides for Chemical Recycling2025
- Author(s)
  Tsuchiya Kousuke、Masunaga Hiroyasu、Numata Keiji
- Journal Title
  
  ACS Sustainable Chemistry & Engineering
  
  Volume: 13 Issue: 10 Pages: 3994-4004
- DOI
  10.1021/acssuschemeng.4c09489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] The Biology of Natural Polymers Accelerates and Expands the Science of Biomacromolecules: A Focus on Structural Proteins2025
- Author(s)
  Numata Keiji
- Journal Title
  
  Biomacromolecules
  
  Volume: 26 Issue: 3 Pages: 1393-1403
- DOI
  10.1021/acs.biomac.4c01621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PLANNED-24H02272
[Journal Article] Expression of spider silk protein in tobacco improves drought tolerance with minimal effects on its mechanotype2025
- Author(s)
  Morey-Yagi Shamitha Rao、Hashida Yoichi、Okamoto Masanori、Odahara Masaki、Suzuki Takehiro、Thagun Chonprakun、Foong Choon Pin、Numata Keiji
- Journal Title
  
  The Plant Journal
  
  Volume: 121 Issue: 2
- DOI
  10.1111/tpj.17213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Silk Proteins: Designs from Nature with Multipurpose Utility and Infinite Future Possibilities2024
- Author(s)
  Numata Keiji、Kaplan David L.
- Journal Title
  
  Advanced Materials
  
  Volume: - Issue: 22
- DOI
  10.1002/adma.202411256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Identification of a highly efficient chloroplast-targeting peptide for plastid engineering2024
- Author(s)
  Thagun Chonprakun、Odahara Masaki、Kodama Yutaka、Numata Keiji
- Journal Title
  
  PLOS Biology
  
  Volume: 22 Issue: 9 Pages: e3002785-e3002785
- DOI
  10.1371/journal.pbio.3002785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Chemoenzymatic Synthesis of Poly-<scp>l</scp>-lysine via Esterification with Alcohol in One-Pot2024
- Author(s)
  Terada Kayo、Tsuchiya Kousuke、Lamprou Alexandros、Numata Keiji
- Journal Title
  
  ACS Polymers Au
  
  Volume: 5 Issue: 1 Pages: 26-34
- DOI
  10.1021/acspolymersau.4c00073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Spider Silk: Rapid, Bottom‐Up Self‐Assembly of MaSp1 into Hierarchically Structured Fibers Through Biomimetic Processing2024
- Author(s)
  Malay Ali D.、Oktaviani Nur Alia、Chen Jianming、Numata Keiji
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 35 Issue: 15
- DOI
  10.1002/adfm.202408175
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Analysis of marker gene transfer from chloroplasts to mitochondria in heat-shocked and selection-pressured tobacco2024
- Author(s)
  Odahara Masaki、Mori Maai、Numata Keiji
- Journal Title
  
  Plant Gene
  
  Volume: 40 Pages: 100473-100473
- DOI
  10.1016/j.plgene.2024.100473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PLANNED-24H02272, KAKENHI-PROJECT-22K05625
[Journal Article] Regiocontrol of the Bulk Polymerization of Lysine Ethyl Ester by the Selection of Suitable Immobilized Enzyme Catalysts2024
- Author(s)
  Tsuchiya Kousuke、Terada Kayo、Kurita Taichi、Watanabe Takumi、Lamprou Alexandros、Numata Keiji
- Journal Title
  
  Biomacromolecules
  
  Volume: 25 Issue: 8 Pages: 5110-5120
- DOI
  10.1021/acs.biomac.4c00497
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PROJECT-23KJ1250
[Journal Article] Synthesis of All-Peptide-Based Rotaxane from a Proline-Containing Cyclic Peptide2024
- Author(s)
  Kurita Taichi、Higashi Masahiro、Gimenez-Dejoz Joan、Fujita Seiya、Uji Hirotaka、Sato Hirofumi、Numata Keiji
- Journal Title
  
  Biomacromolecules
  
  Volume: 25 Issue: 6 Pages: 3661-3670
- DOI
  10.1021/acs.biomac.4c00257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PROJECT-23KJ1250
[Journal Article] Peptide-mediated gene and protein delivery systems to plant mitochondria for modifying mitochondrial functions2024
- Author(s)
  Abe Naoya、Numata Keiji
- Journal Title
  
  Polymer Journal
  
  Volume: 57 Issue: 1 Pages: 57-68
- DOI
  10.1038/s41428-024-00973-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PLANNED-24H02272
[Journal Article] Posttranslational modifications in spider silk influence conformation and dimerization dynamics2024
- Author(s)
  Craig H. C.、Malay A. D.、Hayashi F.、Mori M.、Arakawa K.、Numata K.
- Journal Title
  
  MRS Bulletin
  
  Volume: 49 Issue: 12 Pages: 1192-1204
- DOI
  10.1557/s43577-024-00771-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Utilization of lysed and dried bacterial biomass from the marine purple photosynthetic bacterium Rhodovulum sulfidophilum as a sustainable nitrogen fertilizer for plant production2024
- Author(s)
  Morey-Yagi Shamitha Rao、Kinoshita Yu、Motoki Ko、Iwahashi Yu、Hanh Dao Duy、Kato Shota、Nakano Ryohei、Ochiai Kumiko、Kobayashi Masaru、Nakazaki Tetsuya、Numata Keiji
- Journal Title
  
  npj Sustainable Agriculture
  
  Volume: 2 Issue: 1 Pages: 10-10
- DOI
  10.1038/s44264-024-00018-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PROJECT-23K19294, KAKENHI-PROJECT-24K17887
[Journal Article] Carbon nanotubes functionalized with α-aminoisobutyric acid-containing peptide increase gene delivery efficiency in plant mitochondria2024
- Author(s)
  Law Simon Sau Yin、Kuzumoto Mako、Fujita Seiya、Fujigaya Tsuyohiko、Numata Keiji
- Journal Title
  
  Polymer Journal
  
  Volume: 56 Issue: 10 Pages: 915-924
- DOI
  10.1038/s41428-024-00927-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PROJECT-24K17831
[Journal Article] The structural and functional impacts of rationally designed cyclic peptides on self-assembly-mediated functionality2024
- Author(s)
  Kurita Taichi、Numata Keiji
- Journal Title
  
  Physical Chemistry Chemical Physics
  
  Volume: 26 Issue: 46 Pages: 28776-28792
- DOI
  10.1039/d4cp02759k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PROJECT-23KJ1250
[Journal Article] Poly(A) Tail Length of Messenger RNA Regulates Translational Efficiency of the Mitochondria-Targeting Delivery System2024
- Author(s)
  Yoshinaga Naoto、Numata Keiji
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 10 Issue: 10 Pages: 6344-6351
- DOI
  10.1021/acsbiomaterials.4c01169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PLANNED-24H02272
[Journal Article] Development of a Versatile Plant-Derived Mitochondrial Targeting Sequence Based on a Reporter Protein Sorting Analysis and Biological Information2024
- Author(s)
  Abe Naoya、Odahara Masaki、Morey Shamitha Rao、Numata Keiji
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 19 Issue: 12 Pages: 2515-2524
- DOI
  10.1021/acschembio.4c00625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270, KAKENHI-PLANNED-24H02272
[Journal Article] A Chimeric Peptide for Shielding Plant Photosynthetic Systems against Excess Light Stress via Chloroplast-Targeted ROS Quenching2024
- Author(s)
  Miyamoto Takaaki、Morey-Yagi Shamitha Rao、Numata Keiji
- Journal Title
  
  JACS Au
  
  Volume: 4 Issue: 12 Pages: 4691-4699
- DOI
  10.1021/jacsau.4c00478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Synthesis of Semiaromatic AA/BB-Type Polyamides via Chemoenzymatic Polycondensation2024
- Author(s)
  Ueno Yusuke、Tsuchiya Kousuke、Masunaga Hiroyasu、Numata Keiji
- Journal Title
  
  Macromolecules
  
  Volume: 57 Issue: 24 Pages: 11658-11669
- DOI
  10.1021/acs.macromol.4c02125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Tunable thermal diffusivity of silk protein assemblies based on their structural control and photo-induced chemical cross-linking2024
- Author(s)
  Tanaka Michihiro、Sawada Toshiki、Numata Keiji、Serizawa Takeshi
- Journal Title
  
  RSC Advances
  
  Volume: 14 Issue: 18 Pages: 12449-12453
- DOI
  10.1039/d3ra06473e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05182, KAKENHI-ORGANIZER-24H02270
[Journal Article] Ampholytic Peptides Consisting of an Alternating Lysine/Glutamic Acid Sequence for the Simultaneous Formation of Polyion Complex Vesicles2024
- Author(s)
  Tsuchiya Kousuke、Fujita Seiya、Numata Keiji
- Journal Title
  
  ACS Polymers Au
  
  Volume: 4 Issue: 4 Pages: 320-330
- DOI
  10.1021/acspolymersau.4c00029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Journal Article] Effect of Oligomers Derived from Biodegradable Polyesters on Eco- and Neurotoxicity2023
- Author(s)
  Yoshinaga Naoto、Tateishi Ayaka、Kobayashi Yasuaki、Kubo Tomohiro、Miyakawa Hitoshi、Satoh Kotaro、Numata Keiji
- Journal Title
  
  Biomacromolecules
  
  Volume: tbd Issue: 6 Pages: 2721-2729
- DOI
  10.1021/acs.biomac.3c00160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05735, KAKENHI-PLANNED-20H05734
[Journal Article] Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous Multiple Gene Expression2023
- Author(s)
  Yoshinaga Naoto、Miyamoto Takaaki、Odahara Masaki、Takeda‐Kamiya Noriko、Toyooka Kiminori、Nara Seia、Nishimura Haruna、Ling Feng、Su'etsugu Masayuki、Yoshida Minoru、Numata Keiji
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 34 Issue: 8 Pages: 2306070-2306070
- DOI
  10.1002/adfm.202306070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14575, KAKENHI-PLANNED-23H04882, KAKENHI-PROJECT-22H04975, KAKENHI-PROJECT-23H05473
[Journal Article] Advancing Biomolecule Delivery in Plants: Harnessing Synthetic Nanocarriers to Overcome Multiscale Barriers for Cutting-Edge Plant Bioengineering2023
- Author(s)
  Miyamoto Takaaki、Numata Keiji
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 96 Issue: 9 Pages: 1026-1044
- DOI
  10.1246/bcsj.20230147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14575, KAKENHI-PROJECT-22H04975
[Journal Article] Crystallization-induced mechanofluorescence for visualization of polymer crystallization2021
- Author(s)
  Kato Sota、Furukawa Shigeki、Aoki Daisuke、Goseki Raita、Oikawa Kazusato、Tsuchiya Kousuke、Shimada Naohiko、Maruyama Atsushi、Numata Keiji、Otsuka Hideyuki
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-7
- DOI
  10.1038/s41467-020-20366-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05735, KAKENHI-PROJECT-17H01205, KAKENHI-PROJECT-19J23009
[Journal Article] Endosome-escaping micelle complexes dually equipped with cell-penetrating and endosome-disrupting peptides for efficient DNA delivery into intact plants2021
- Author(s)
  Miyamoto Takaaki、Tsuchiya Kousuke、Numata Keiji
- Journal Title
  
  Nanoscale
  
  Volume: 13 Issue: 11 Pages: 5679-5692
- DOI
  10.1039/d0nr08183c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15411, KAKENHI-PLANNED-20H05735
[Journal Article] Xanthurenic Acid Is the Main Pigment of Trichonephila clavata Gold Dragline Silk2021
- Author(s)
  Fujiwara Masayuki、Kono Nobuaki、Hirayama Akiyoshi、Malay Ali D.、Nakamura Hiroyuki、Ohtoshi Rintaro、Numata Keiji、Tomita Masaru、Arakawa Kazuharu
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 4 Pages: 563-563
- DOI
  10.3390/biom11040563
- Data Source
  KAKENHI-PLANNED-20H05735
[Journal Article] Synthetic Mitochondria-Targeting Peptides Incorporating α-Aminoisobutyric Acid with a Stable Amphiphilic Helix Conformation in Plant Cells2021
- Author(s)
  Kayo Terada, Joan Gimenez-Dejoz, Taichi Kurita, Kazusato Oikawa, Hirotaka Uji, Kousuke Tsuchiya, and Keiji Numata
- Journal Title
  
  ACS Biomaterials SCIENCE & ENGINEERING
  
  Volume: 7(4) Issue: 4 Pages: 1475-1484
- DOI
  10.1021/acsbiomaterials.0c01533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05718, KAKENHI-PLANNED-20H05735
[Journal Article] Lipid Membrane Interaction of Peptide/DNA Complexes Designed for Gene Delivery2021
- Author(s)
  Yilmaz Neval、Kodama Yutaka、Numata Keiji
- Journal Title
  
  Langmuir
  
  Volume: 37 Issue: 5 Pages: 1882-1893
- DOI
  10.1021/acs.langmuir.0c03320
- Data Source
  KAKENHI-PLANNED-20H05735
[Journal Article] Mitochondrial movement during its association with chloroplasts in Arabidopsis thaliana2021
- Author(s)
  Oikawa Kazusato、Imai Takuto、Thagun Chonprakun、Toyooka Kiminori、Yoshizumi Takeshi、Ishikawa Kazuya、Kodama Yutaka、Numata Keiji
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-13
- DOI
  10.1038/s42003-021-01833-8
- NAID
  120006993844
- Data Source
  KAKENHI-PLANNED-20H05735
[Journal Article] Special issue: CO2: capture of, utilization of, and degradation into2021
- Author(s)
  Nakano Koji、Hoshino Yu、Numata Keiji、Tanaka Keiji
- Journal Title
  
  Polymer Journal
  
  Volume: 53 Issue: 1 Pages: 1-2
- DOI
  10.1038/s41428-020-00427-1
- Data Source
  KAKENHI-PLANNED-20H05735
[Journal Article] Aqueous spinning system with a citrate buffer for highly extensible silk fibers2020
- Author(s)
  Chen Jianming、Ohta Yoshinori、Nakamura Hiroyuki、Masunaga Hiroyasu、Numata Keiji
- Journal Title
  
  Polymer Journal
  
  Volume: 53 Issue: 1 Pages: 179-189
- DOI
  10.1038/s41428-020-00419-1
- Data Source
  KAKENHI-PLANNED-20H05735
[Journal Article] Microbial prospection of an Amazonian blackwater lake and whole-genome sequencing of bacteria capable of polyhydroxyalkanoate synthesis2020
- Author(s)
  Castro Lorena M.、Foong Choon Pin、Higuchi-Takeuchi Mieko、Morisaki Kumiko、Lopes Eraldo F.、Numata Keiji、Mota Adolfo J.
- Journal Title
  
  Polymer Journal
  
  Volume: 53 Issue: 1 Pages: 191-202
- DOI
  10.1038/s41428-020-00424-4
- Data Source
  KAKENHI-PLANNED-20H05735
[Journal Article] Peptide-Based Polyion Complex Vesicles That Deliver Enzymes into Intact Plants To Provide Antibiotic Resistance without Genetic Modification2020
- Author(s)
  Fujita Seiya、Motoda Yoko、Kigawa Takanori、Tsuchiya Kousuke、Numata Keiji
- Journal Title
  
  Biomacromolecules
  
  Volume: 22 Issue: 3 Pages: 1080-1090
- DOI
  10.1021/acs.biomac.0c01380
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05735, KAKENHI-PROJECT-19K15643
[Journal Article] Use of extension-deformation-based crystallization of silk fibres to differentiate their functions in nature2015
- Author(s)
  Keiji Numata, Hiroyasu Masunaga, Takaaki Hikima, Sono Sasaki, Kazuhide Sekiyama, Masaki Takata
- Journal Title
  
  Soft Matter
  
  Volume: 11 Issue: 31 Pages: 6335-6342
- DOI
  10.1039/c5sm00757g
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25810110
[Journal Article] Crystal structure and physical properties of Antheraea yamamai silk fibers: long poly(alanine) sequences are partially in crystalline region2015
- Author(s)
  Keiji Numata, Ryota Sato, Kenjiro Yazawa, Takaaki Hikima, Hiroyasu Masunaga
- Journal Title
  
  polymer
  
  Volume: 77 Pages: 87-94
- DOI
  10.1016/j.polymer.2015.09.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25810110
[Journal Article] Poly(amino acid)s/polypeptides as potential functional and structural materials2015
- Author(s)
  Keiji Numata
- Journal Title
  
  Polymer Journal
  
  Volume: 47 Issue: 8 Pages: 537-545
- DOI
  10.1038/pj.2015.35
- NAID
  40020540927
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25810110
[Journal Article] Silk-Pectin Hydrogel with Superior Mechanical Properties, Biodegradability, and Biocompatibility2014
- Author(s)
  Keiji Numata, Shoya Yamazaki, Jo-Ann Chuah, Takuya Katashima, Naofumi Naga, Takamasa Sakai
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 14 Issue: 6 Pages: 799-806
- DOI
  10.1002/mabi.201300482
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25810110
[Journal Article] Biopolymer-based Nanoparticles for Drug/Gene Delivery and Tissue Engineering.2013
- Author(s)
  Sachiko Kaihara Nitta, Keiji Numata
- Journal Title
  
  International Journal of Molecular Sciences, Special Issue"Bioactive Nanoparticles 2012"
  
  Volume: Volume 14, Issue 1 Pages: 1629-1654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750264
[Journal Article] Rapid and Efficient Gene Delivery into Plant Cells Using Designed Peptide Carriers.2013
- Author(s)
  Manoj Lakshmanan, Yutaka Kodama, Takeshi Yoshizumi, Kumar Sudesh, Keiji Numata
- Journal Title
  
  Biomacromolecules
  
  Volume: Volume 14, Issue 1 Pages: 10-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750264
[Journal Article] Silk-Based Nano-Complexes with Tumor Homing Peptides for Tumor-Specific Gene Delivery2012
- Author(s)
  Keiji Numata
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 12 Issue: 1 Pages: 75-82
- DOI
  10.1002/mabi.201100274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750264
[Journal Article] Silk-Based Nano-Complexes with Tumor Homing Peptides for Tumor-Specific Gene Delivery.2012
- Author(s)
  Keiji Numata, Aneta J Mieszawska, Laura A. Kvenvold, David L Kaplan
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: Volume 12, Issue 1 Pages: 75-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750264
[Journal Article] Silk-based nanocomplexes with tumor-homing peptides for tumor-specific gene delivery.2012
- Author(s)
  Numata K, Mieszawska-Czajkowska AJ, Kvenvold LA, Kaplan DL
- Journal Title
  
  Macromol Biosci.
  
  Volume: 1 Pages: 75-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750264
[Journal Article] Spider Silk-Based Gene Carriers for Tumor Cell-Specific Delivery.2011
- Author(s)
  Keiji Numata, Michaela R Reagan, Robert H Goldstein, Michael Rosenblatt, David L Kaplan
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: Volume 22, Issue 8 Pages: 1605-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Predictability of environment-dependent formation of the behavior of DNAs in human mitochondria2025
- Author(s)
  S. Takahashi, L. Liu, S. Ghosh, T. Endoh, N. Yoshinaga, K. Numata, N. Sugimoto
- Organizer
  To B or Not to B Symposium 2025
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04975
[Presentation] New Data Science in Nucleic Acids Chemistry (20) : G-quadruplex DNA formations depending on the environments in the mitochondrial matrix2025
- Author(s)
  L. Lutan, S. Takahashi, G. Sarptarshi, T. Endoh, N. Yoshinaga, K. Numata, N. Sugimoto
- Organizer
  日本化学会第105回春季年会
- Data Source
  KAKENHI-PROJECT-22H04975
[Presentation] Organelle-targeted delivery within plants using carbon nanotube-polymer composites2025
- Author(s)
  Simon Law, Keiji Numata
- Organizer
  27th Plant Organelle WS
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] Peptide-mediated DNA/protein delivery system for plant organellar modifications2024
- Author(s)
  Keiji Numata
- Organizer
  ICPMB2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] ミトコンドリアでの多重タンパク質発現を可能とするミトコンドリア標的遺伝子送達技術の開発2024
- Author(s)
  吉永直人、沼田圭司
- Organizer
  第23回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] 高分子水溶液の広角 X 線散乱2024
- Author(s)
  井田大地・渡部遼・沼田圭司
- Organizer
  2024年繊維学会秋季研究発表会
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] 肝臓ミトコンドリアに対する選択的膜透過糖ペプチドの開発2024
- Author(s)
  野村幸汰、大庭誠、沼田圭司
- Organizer
  第18回バイオ関連化学シンポジウム（第39回生体機能関連化学シンポジウム、第27回バイオテクノロジー部会シンポジウム）
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] New Data Science in Nucleic Acids Chemistry (5): Effect of local environments on the stability of nucleic acids in mitochondria2024
- Author(s)
  S. Ghosh, L. Liu, S. Takahashi, T. Endoh, N. Yoshinaga, K. Numata, N. Sugimoto
- Organizer
  日本化学会第104回春季年会
- Data Source
  KAKENHI-PROJECT-22H04975
[Presentation] 植物を光酸化ストレスから保護する葉緑体標的型抗酸化ペプチドの設計2024
- Author(s)
  宮本昂明、沼田圭司
- Organizer
  第18回バイオ関連化学シンポジウム（第39回生体機能関連化学シンポジウム、第27回バイオテクノロジー部会シンポジウム）
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] ジチロシン架橋によるレジリン様ポリペプチドの化学酵素合成2024
- Author(s)
  寺田佳世、武村翔吾、辻優依、土屋康佑、沼田圭司
- Organizer
  第18回バイオ関連化学シンポジウム（第39回生体機能関連化学シンポジウム、第27回バイオテクノロジー部会シンポジウム）
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] ミトコンドリアにおける外因性 mRNA 発現効率の最大化2024
- Author(s)
  吉永直人、沼田圭司
- Organizer
  第34 回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] 糖リガンドによる肝臓ミトコンドリア選択的透過ペプチドの開発2024
- Author(s)
  野村幸汰、大庭誠、沼田圭司
- Organizer
  第34 回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-ORGANIZER-24H02270
[Presentation] バイオ・高分子材料のビッグデータ構築と材料開発への利用 / Digital transformation in biological and polymeric materials2023
- Author(s)
  沼田圭司
- Organizer
  JapanNano第21回マテリアル戦略総合シンポジウム
- Data Source
  KAKENHI-PROJECT-22H04975
[Presentation] シグナルペプチドを利用した遺伝子送達の現状2022
- Author(s)
  沼田圭司
- Organizer
  遺伝子デリバリー研究会
- Data Source
  KAKENHI-PROJECT-22H04975
[Presentation] 構造材料を志向したポリペプチドの生合成と材料設計2016
- Author(s)
  沼田圭司
- Organizer
  高分子学会　関東高分子若手研究会サマーキャンプ
- Place of Presentation
  東京農工大学館山荘（千葉県・館山市）
- Year and Date
  2016-08-04
- Invited
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Chemoenzymatic synthesis and material design of polypeptides2016
- Author(s)
  Keiji Numata
- Organizer
  The 3rd International Symposium for Green-Innovation Polymers
- Place of Presentation
  北陸先端大学（石川県・能美市）
- Year and Date
  2016-03-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] アミノ酸から構成される高分子の合成および構造材料への展開2016
- Author(s)
  沼田圭司
- Organizer
  高分子学会埼玉地区懇話会
- Place of Presentation
  リンテック（埼玉県・蕨市）
- Year and Date
  2016-01-22
- Invited
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Silk and Related Peptides as Structural Materials2015
- Author(s)
  Keiji Numata
- Organizer
  5TH MOLECULAR MATERIALS MEETING (M3)
- Place of Presentation
  Singapore（Singapore）
- Year and Date
  2015-08-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Antheraea yamamaiシルクの結晶構造とその機械的および熱的性質に関する研究2015
- Author(s)
  沼田圭司、佐藤涼太、増永啓康、引間孝明
- Organizer
  第64回高分子学会討論会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Potential as structural materials and chemo-enzymatic synthesis of poly(amino acid)2015
- Author(s)
  Keiji Numata
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu（米国）
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Structural analysis of silk fibers and importance of the beta-sheet formation2014
- Author(s)
  Keiji Numata
- Organizer
  International Silk Conference
- Place of Presentation
  上海
- Year and Date
  2014-10-08
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] クモ糸およびカイコ由来シルクの延伸過程における結晶構造解析2014
- Author(s)
  沼田圭司、増永啓康、引間孝明
- Organizer
  第63回高分子学会年次大会
- Place of Presentation
  名古屋
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] ペプチドの化学酵素合成およびバイオマス材料としての応用2014
- Author(s)
  沼田圭司
- Organizer
  第4回CSJ化学フェスタ2014
- Place of Presentation
  船堀
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Virus-inspired gene delivery systems into plant cells via functional polypeptides2012
- Author(s)
  Keiji Numata
- Organizer
  Gordon Research Conference on Bioinspired Materials
- Place of Presentation
  USA
- Year and Date
  2012-06-27
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] ペプチドポリマーによるソフトマテリアルデザイン2012
- Author(s)
  沼田圭司
- Organizer
  第二回新規材料創成を目指した合成生物学
- Place of Presentation
  横浜
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Rapid and efficient gene delivery into plant cells using fusion peptide carrier2012
- Author(s)
  Keiji Numata, Yutaka Kodama, Takeshi Yoshizumi
- Organizer
  International Polymer Conference
- Place of Presentation
  Kobe, Japan
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Chemo-enzymatic synthesis of peptide polymers and their application for gene delivery2012
- Author(s)
  Keiji Numata
- Organizer
  American Chemical Society, Symposium on "Green Polymer Chemistry: Biocatalysis and Biobased Materials"
- Place of Presentation
  USA
- Year and Date
  2012-08-21
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Gene delivery systems mediated polypeptides into animal and plant cells2012
- Author(s)
  Keiji Numata
- Organizer
  Gordon Research Conference on Peptides, Chemistry & Biology of
- Place of Presentation
  USA
- Year and Date
  2012-02-22
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] 酵素触媒を用いた新規バイオポリマー合成2012
- Author(s)
  沼田圭司
- Organizer
  植物科学シンポジウム植物最先端研究への期待
- Place of Presentation
  品川、コクヨ
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Gene delivery systems mediated polypeptides into animal and plant cells2012
- Author(s)
  Keiji Numata
- Organizer
  Gordon Research Conference on Peptides, Chemistry & Biology of
- Place of Presentation
  カリフォルニア、米国
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] バイオポリエステルおよびバイオポリアミドの生合成とその応用2012
- Author(s)
  沼田圭司
- Organizer
  エコマテリアル研究会
- Place of Presentation
  東京
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Material design of silk polymers for hydrogel and nanoparticle2011
- Author(s)
  Keiji Numata
- Organizer
  The 3rd International Conference on Biobased Polymers(招待講演)
- Place of Presentation
  北京、中国
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Silk hydrogel and nanoparticle as biomaterials2011
- Author(s)
  Keiji Numata
- Organizer
  Polymers for Advanced Technologies
- Place of Presentation
  Lodz, Poland
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] apid and efficient gene delivery into plant cells using fusion peptide carrier
- Author(s)
  Keiji Numata
- Organizer
  International Polymer Conference
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] バイオポリエステルおよびバイオポリアミドの生合成とその応用
- Author(s)
  沼田圭司
- Organizer
  エコマテリアル研究会
- Place of Presentation
  東京大学
- Invited
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Chemo-enzymatic synthesis of peptide polymers and their application for gene delivery
- Author(s)
  Keiji Numata
- Organizer
  American Chemical Society, Symposium on "Green Polymer Chemistry: Biocatalysis and Biobased Materials"
- Place of Presentation
  Philadelphia USA
- Invited
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] Silk hydrogel with high strength and biocompatibility
- Author(s)
  Keiji Numata
- Organizer
  Tissue Engineering and Regenerative Medicine International Society; Asia Pacific Chapter (TERMIS-AP)
- Place of Presentation
  Wuzhen, China
- Invited
- Data Source
  KAKENHI-PROJECT-25810110
[Presentation] Virus-inspired gene delivery systems into plant cells via functional polypeptides
- Author(s)
  Keiji Numata
- Organizer
  Gordon Research Conference on Bioinspired Materials
- Place of Presentation
  Davidson USA
- Data Source
  KAKENHI-PROJECT-23750264
[Presentation] 酵素触媒を用いた新規バイオポリマー合成
- Author(s)
  沼田圭司
- Organizer
  植物科学シンポジウム　植物最先端研究への期待
- Place of Presentation
  品川
- Invited
- Data Source
  KAKENHI-PROJECT-23750264

1. 山田勇磨 (60451431)

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2. 畝山多加志 (10524720)

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3. 佐藤浩太郎 (70377810)

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4. 酒井崇匡 (70456151)

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5. 杉本直己 (60206430)

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6. 松浦和則 (60283389)

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7. 遠藤玉樹 (90550236)

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8. 高橋俊太郎 (40456257)

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9. 建石寿枝 (20593495)

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11. 石原直忠 (10325516)

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16. 庄司佳祐 (30880116)

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17. 神吉智丈 (50398088)

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18. 木内隆史 (60622892)

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19. 高梨秀樹 (60707149)

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20. 細川正人 (60722981)

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21. 佐藤美由紀 (70321768)

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22. 西村芳樹 (70444099)

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23. 小笠原絵美 (70778274)

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24. 矢守航 (90638363)

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25. Law SimonSauYin (60846682)

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28. DAS KARMAKAR PUJA

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29. 宮本昂明

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30. 寺田佳世

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31. 澤田敏樹

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Numata Keiji 沼田 圭司

NUMATA Keiji 沼田 圭司

Research Projects

Research Products

Co-Researchers

クモ牽引糸タンパク質の分子機構を明らかにし、クモ糸の階層構造を人工的に再現するPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

ヒトへの遺伝子導入の為の自己組織化高分子ペプチドシステムのバイオミメティクス製作Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Genomic regulation of intracellular symbiotic organelles: from technological innovation to understanding and application of life phenomena

Principal Investigator

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Review Section

Research Institution

オルガネラへの核酸および生理活性分子導入Principal Investigator

Principal Investigator

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Review Section

Research Institution

Quantitative prediction of nucleic acid structures and functions affected by spaciotemporal environmental factors in cells

Principal Investigator

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Review Section

Research Institution

Precision Degradation of Polymer and Polymeric MaterialArea Organizer

Area Organizer

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Polymer characterization platform for precise polymer degradationsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Precise characterizations of degradation products and assessment of their impact on the biological environmentsPrincipal Investigator

Principal Investigator

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Review Section

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Plant cell wall-mimicking silk-pectin hydrogel for coral reef regenerationPrincipal Investigator

Principal Investigator

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Gene carriers containing functional peptides for breast cancer treatmentPrincipal Investigator

Principal Investigator

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Research Institution

[Book] Engineering peptide-based carriers for drug and gene delivery.2014

Author(s)

Publisher

Data Source

[Book] Silk Biomaterials in Tissue Engineering and Regenerative Medicine2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Synthesis of cyclic peptide-based [2]rotaxanes <i>via</i> copper-catalyzed azide?alkyne cycloaddition2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemoenzymatic Polymerization/Depolymerization of Semiaromatic Polyamides for Chemical Recycling2025

Author(s)

Journal Title

Numata Keiji 沼田圭司

NUMATA Keiji 沼田圭司