NAKAGAWA TOHRU 中川徹

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NAKAGAWA Tohru 中川徹

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Researcher Number	40591730
Other IDs
Affiliation (Current)	2025: 帝京大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 帝京大学, 医学部, 教授 2017 – 2023: 帝京大学, 医学部, 教授 2013 – 2016: 東京大学, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Basic Section 56030:Urology-related / Urology / Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Basic Section 47060:Clinical pharmacy-related / Tumor therapeutics
Keywords	Principal Investigator ネオアンチゲン / 癌精巣抗原 / Tim-3 / PD-1 / 免疫チェックポイント阻害剤 / ガンマデルタT細胞 / 免疫療法 / NKG2D / γδT細胞 / CIBERSORT / 次世代シーケンサー / 腫瘍免疫 / 尿路上皮癌 … More Except Principal Investigator … More 免疫療法 / 腎細胞癌 / 超音波 / 膀胱癌 / マイクロバブル / 薬剤服用歴 / イムノグラム / 免疫チェックポイント阻害薬 / ペムブロリズマブ / 尿路上皮癌 / ＥＳＳ２ / ＲＯＲγ / ESS2 / RORγ / 前立腺癌 / IFNg / HLA-A2トランスジェニックマウス / MHCクラスI結合予測 / HLA-A2 トランスジェニックマウス / IFN-gamma / トランスジェニックマウス / HLA-A2 / T細胞 / MHC class I 結合予測 / ネオエピトープ / 腎がん / MHC結合予測アルゴリズム / ネオ抗原 / 遺伝子変異 / 腎癌 / クロマチン異常 / 癌進展 / クロマチン制御関連遺伝子 / 癌の進展 / クロマチン制御遺伝子 / 分子標的薬 / インターフェロン / 樹状細胞療法 Less

薬剤性認知症回避を目指した抗コリン薬の新規リスク指標開発
- Principal Investigator
  
  黄倉崇
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Teikyo University
Development of a Novel Therapy for Invasive Bladder Cancer Using Ultrasound-Responsive Microbubbles
- Principal Investigator
  
  川合剛人
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
  Basic Section 90140:Medical technology assessment-related
  Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
- Research Institution
  International University of Health and Welfare
Tailor-made immunotherapy strategy for urothelial cancer using immunogram
- Principal Investigator
  
  Kawai Taketo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Teikyo University
Development of immunotherapy for castration resistant prostate cancer targeting a novel cofactor of RORgamma
- Principal Investigator
  
  Takahashi Sayuri
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  The University of Tokyo
  Teikyo University
Development of cancer immunotherapy targeting mutation-derived neoantigens
- Principal Investigator
  
  MATSUSHITA Hirokazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Aichi Cancer Center Research Institute
  The University of Tokyo
Analysis of intra-tumor immune response toward development of autologous gamma-delta T-cell transfer therapy in patients with advanced urothelial carcinomaPrincipal Investigator
- Principal Investigator
  
  Nakagawa Tohru
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Teikyo University
  The University of Tokyo
Role of the chromatin regulating genes in the progression of renal cell carcinoma
- Principal Investigator
  
  Kume Haruki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The University of Tokyo
DC-based vaccination combined with interferon for metastatic renal cell carcinoma
- Principal Investigator
  
  ENOMOTO Yutaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Validation of a drug-based score in advanced urothelial carcinoma treated with pembrolizumab2023
- Author(s)
  Taguchi S, Kawai T, Buti S, Bersanelli M, Uemura Y, Kishitani K, Miyakawa J, Sugimoto K, Nakamura Y, Niimi F, Kaneko T, Kamei J, Obinata D, Yamaguchi K, Kakutani S, Kanazawa K, Sugihara Y, Tokunaga M, Akiyama Y, Yamada Y, Sato Y, Yamada D, Enomoto Y, Nishimatsu H, Fujimura T, Fukuhara H, Nakagawa T, Takahashi S, Kume H
- Journal Title
  
  Immunotherapy
  
  Volume: 15 Issue: 11 Pages: 827
- DOI
  10.2217/imt-2023-0028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09368, KAKENHI-PROJECT-23K15781
[Journal Article] Impact of immune-related adverse events on the therapeutic efficacy of pembrolizumab in urothelial carcinoma: A multicenter retrospective study using time-dependent analysis2022
- Author(s)
  Kawai Taketo、Taguchi Satoru、Nakagawa Tohru、Kamei Jun、Nakamura Yu、Obinata Daisuke、Yamaguchi Kenya、Kaneko Tomoyuki、Kakutani Shigenori、Tokunaga Mayuko、Uemura Yukari、Sato Yusuke、Enomoto Yutaka、Nishimatsu Hiroaki、Fujimura Tetsuya、Fukuhara Hiroshi、Takahashi Satoru、Kume Haruki
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 10 Issue: 2 Pages: e003965-e003965
- DOI
  10.1136/jitc-2021-003965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09368, KAKENHI-PROJECT-19K09720
[Journal Article] Transcriptional coregulator Ess2 controls survival of post-thymic CD4+ T cells through the Myc and IL-7 signaling pathways2022
- Author(s)
  Takada I‡, Hidano S‡, Takahashi S‡, Ogawa H, Tsuchiya M, Yokoyama A, Sato S, Ochi H, Nakagawa T, Kobayashi T, Nakagawa S, Makishima M
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Pages: 102342-102342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09162
[Journal Article] Prognostic significance of the albumin-to-globulin ratio for advanced urothelial carcinoma treated with pembrolizumab: a multicenter retrospective study2021
- Author(s)
  Taguchi Satoru、Kawai Taketo、Nakagawa Tohru、Nakamura Yu、Kamei Jun、Obinata Daisuke、Yamaguchi Kenya、Kaneko Tomoyuki、Kakutani Shigenori、Tokunaga Mayuko、Uemura Yukari、Sato Yusuke、Fujimura Tetsuya、Fukuhara Hiroshi、Enomoto Yutaka、Nishimatsu Hiroaki、Takahashi Satoru、Kume Haruki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15623-15623
- DOI
  10.1038/s41598-021-95061-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09368, KAKENHI-PROJECT-19K09720
[Journal Article] Clinical significance of random bladder biopsy in primary T1 bladder cancer2018
- Author(s)
  Otsuka Masafumi、Taguchi Satoru、Nakagawa Tohru、Morikawa Teppei、Maekawa Shigekatsu、Miyakawa Jimpei、Matsumoto Akihiko、Miyazaki Hideyo、Fujimura Tetsuya、Fukuhara Hiroshi、Kume Haruki、Igawa Yasuhiko、Homma Yukio
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 8 Pages: 665-670
- DOI
  10.3892/mco.2018.1587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10577, KAKENHI-PROJECT-16K10996
[Journal Article] Preoperative chronic kidney disease is predictive of oncological outcome of radical cystectomy for bladder cancer2018
- Author(s)
  4.Matsumoto A, Nakagawa T, Kanatani A, Ikeda M, Kawai T, Miyakawa J, Taguchi, S, Naito A, Otsuka M, Nakanishi Y, Suzuki M, Koga F, Nagase Y, Kondo Y, Okaneya T, Tanaka Y, Miyazaki H, Fujimura T, Fukuhara H, Kume H, Igawa Y,Homma Y.
- Journal Title
  
  World J Urol
  
  Volume: 36 Issue: 2 Pages: 249
- DOI
  10.1007/s00345-017-2141-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10577, KAKENHI-PROJECT-16K10996
[Journal Article] Loss of Stromal Antigen 2 (STAG2) Expression in Upper Urinary Tract Carcinoma: Differential Prognostic Effect According to the Ki-67 Proliferating Index2017
- Author(s)
  1.Miyakawa J, Morikawa T, Miyama Y, Nakagawa T, Kawai T, Homma Y, Fukayama M.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 24 Issue: 13 Pages: 4059
- DOI
  10.1245/s10434-017-6097-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10577, KAKENHI-PROJECT-17K15635
[Journal Article] Efficacy of post-nephroureterectomy cisplatin-based adjuvant chemotherapy for locally advanced upper tract urothelial carcinoma: a multi-institutional retrospective study2017
- Author(s)
  2.Nakagawa T, Komemushi Y, Kawai T, Otsuka M, Miyakawa J, Uemura Y, Kanatani A, Taguchi S, Naito A, Suzuki M, Nishimatsu H, Hirano Y, Tanaka Y, Matsumoto A, Miyazaki H, Fujimura T, Fukuhara H, Kume H, Igawa Y, Homma Y.
- Journal Title
  
  World J Urol
  
  Volume: 35 Issue: 10 Pages: 1569
- DOI
  10.1007/s00345-017-2032-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10577
[Journal Article] Nomogram for predicting survival of postcystectomy recurrent urothelial carcinoma of the bladder2017
- Author(s)
  Nakagawa T, Taguchi S, Uemura Y, Kanatani A, Ikeda M, Matsumoto A, Yoshida K, Kawai T, Nagata M, Yamada D, Komemushi Y, Suzuki M, Enomoto Y, Nishimatsu H, Ishikawa A, Nagase Y, Kondo Y, Tanaka Y, Okaneya T, Hirano Y, Shinohara M, Miyazaki H, Fujimura T, Fukuhara H, Kume H, Igawa Y, Homma Y
- Journal Title
  
  Urol Oncol
  
  Volume: 35 Issue: 7 Pages: 457.e15-457.e21
- DOI
  10.1016/j.urolonc.2016.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10577
[Journal Article] Oncologic Outcome of Metastasectomy for Urothelial Carcinoma: Who Is the Best Candidate?2017
- Author(s)
  3.Nakagawa T, Taguchi S, Kanatani A, Kawai T, Ikeda M, Urakami S, Matsumoto A, Komemushi Y, Miyakawa J, Yamada D, Suzuki M, Enomoto Y, Nishimatsu H, Kondo Y, Nagase Y, Hirano Y, Okaneya T, Tanaka Y, Miyazaki H, Fujimura T, Fukuhara H, Kume H, Igawa Y, Homma Y
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 24 Issue: 9 Pages: 2794
- DOI
  10.1245/s10434-017-5970-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10577
[Journal Article] Neoantigen Load, Antigen Presentation Machinery, and Immune Signatures Determine Prognosis in Clear Cell Renal Cell Carcinoma2016
- Author(s)
  Matsushita H, Sato Y, Karasaki T, Nakagawa T, Kume H, Ogawa S, Homma Y, Kakimi K
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 4 Pages: 463-71
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07162
[Journal Article] Neoantigen load, antigen presentation machinery, and immune signatures determine prognosis in clear cell renal cell carcinoma2016
- Author(s)
  Matsushita H, Sato Y, Karasaki T, Nakagawa T, Kume H, Ogawa S, Homma Y, Kakimi K.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 4 Issue: 5 Pages: 463
- DOI
  10.1158/2326-6066.cir-15-0225
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10577, KAKENHI-PROJECT-15H04942
[Journal Article] Neoantigen Load, Antigen Presentation Machinery, and Immune Signatures Determine Prognosis in Clear Cell Renal Cell Carcinoma.2016
- Author(s)
  Matsushita H, Sato Y, Karasaki T, Nakagawa T, Kume H, Ogawa S, Homma Y, Kakimi K.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 未
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462402
[Journal Article] MAGE-A expression, immune microenvironment, and prognosis in upper urinary tract carcinoma2016
- Author(s)
  Makise N, Morikawa T, Nakagawa T, Ichimura T, Kawai T, Matsushita H, Kakimi K, Kume H, Homma Y, Fukayama M.
- Journal Title
  
  Human Pathology
  
  Volume: 50 Pages: 62
- DOI
  10.1016/j.humpath.2015.11.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10577, KAKENHI-PROJECT-25460412
[Presentation] 新規RORγ転写共役因子ESS2遺伝子の同定および前立腺癌増悪のメカニズムの解明2019
- Author(s)
  高橋さゆり,久米春喜,中川徹
- Organizer
  第69回日本泌尿器科学会中部総会
- Data Source
  KAKENHI-PROJECT-18K09162
[Presentation] 核内受容体RORγの新規転写共役因子ESS2は染色体凝縮・分裂を制御し前立腺癌を増悪させる2019
- Author(s)
  高橋さゆり,山田幸央,久米春喜,中川徹
- Organizer
  日本泌尿器腫瘍学会第5回学術集会
- Data Source
  KAKENHI-PROJECT-18K09162
[Presentation] 進行性膀胱癌に対する膀胱全摘術後の補助化学療法の有用性の検討：多施設共同研究．2018
- Author(s)
  1.金谷淳志、松本明彦、川合剛人、池田勝臣、宮川仁平、田口慧、内藤晶裕、大塚真史、中西泰一、東剛司、鈴木基文、古賀文隆、近藤靖司、岡根谷利一、田中良典、久米春喜、中川徹．
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15K10577
[Presentation] 転移性腎細胞癌に対するスニチニブ併用樹状細胞療法2017
- Author(s)
  1.中川徹、松下博和、垣見和宏、松本明彦、宮嵜英世、藤村哲也、福原浩、榎本裕、久米春喜、本間之夫．
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15K10577
[Presentation] Expression of candidate neoantigens in ccRCC patients and its implication on prognosis2015
- Author(s)
  Hirokazu Matsushita, Manami Miyai, Yusuke Sato, Tohru Nakagawa, Haruki Kume, Seishi Ogawa, Yukio Homma, Kazuhiro Kakimi
- Organizer
  第19回日本がん免疫学会総会（ICCIM2015）
- Place of Presentation
  伊藤国際学術研究センター(東京都文京区)
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K10577

1. KAKIMI Kazuhiro (80273358)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. Kawai Taketo (60343133)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Kume Haruki (10272577)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. MATSUSHITA Hirokazu (80597782)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 山田大介 (00623696)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ENOMOTO Yutaka (20280927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Takahashi Sayuri (40313217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 永田政義 (00323668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 東剛司 (50719854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 小林隆志 (30380520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 佐藤悠佑 (20372378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 黄倉崇 (80326123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中紫茉子 (10559925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中谷絵理子 (90803916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宮田敏 (60360343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 丸山一雄 (30130040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAGAWA TOHRU 中川 徹

NAKAGAWA Tohru 中川 徹

Research Projects

Research Products

Co-Researchers

薬剤性認知症回避を目指した抗コリン薬の新規リスク指標開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Novel Therapy for Invasive Bladder Cancer Using Ultrasound-Responsive Microbubbles

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tailor-made immunotherapy strategy for urothelial cancer using immunogram

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of immunotherapy for castration resistant prostate cancer targeting a novel cofactor of RORgamma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of cancer immunotherapy targeting mutation-derived neoantigens

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of intra-tumor immune response toward development of autologous gamma-delta T-cell transfer therapy in patients with advanced urothelial carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of the chromatin regulating genes in the progression of renal cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DC-based vaccination combined with interferon for metastatic renal cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Validation of a drug-based score in advanced urothelial carcinoma treated with pembrolizumab2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of immune-related adverse events on the therapeutic efficacy of pembrolizumab in urothelial carcinoma: A multicenter retrospective study using time-dependent analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptional coregulator Ess2 controls survival of post-thymic CD4+ T cells through the Myc and IL-7 signaling pathways2022

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic significance of the albumin-to-globulin ratio for advanced urothelial carcinoma treated with pembrolizumab: a multicenter retrospective study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of random bladder biopsy in primary T1 bladder cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preoperative chronic kidney disease is predictive of oncological outcome of radical cystectomy for bladder cancer2018

Author(s)

Journal Title

NAKAGAWA TOHRU 中川徹

NAKAGAWA Tohru 中川徹