TSUCHIHASHI Hitoshi 土橋均

Researcher Number	40596029
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2017: 名古屋大学, 医学系研究科, 招へい教員 2015: 名古屋大学, 医学(系)研究科(研究院), その他 2015: 名古屋大学, 医学(系)研究科(研究院), 招へい教員 2015: 名古屋大学, 医学系研究科, 招聘教員 2012 – 2014: 大阪医科大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Physical pharmacy Except Principal Investigator Legal medicine
Keywords	Principal Investigator TOF/TOF / 毛髪分析 / イメージング / 質量分析 / 乱用薬物 / 毛髪 Except Principal Investigator メタボロミクス / タンデム質量分析計 / 法中毒 / カチノン … More / 全自動化 / 飛行時間型質量分析計 / 合成カンナビノイド / 危険ドラッグ / 質量分析 / 法医学 / 法中毒学 / 突然死 / GC-MS / GC-MS/MS / 多剤併用 / 向精神薬 / ラット / 死後経過時間 / 熱中症 Less

Pathophysiological analysis of sudden death related with polypharmacy by metabolomics analysis and it's application to forensic diagnosis
- Principal Investigator
  
  SATO TAKAKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Osaka Medical College
Application of novel mass spectrometric techniques for highly sensitive, specific and speedy identification of new psychoactive substances in human specimens
- Principal Investigator
  
  Ishii Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Legal medicine
- Research Institution
  Nagoya University
Forensic diagnosis for heatstroke-a search for useful biomarkers by metabolic profiling
- Principal Investigator
  
  Suzuki Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Osaka Medical College
Mass spectrometry imaging of single hair specimens for the reliable chronological estimation of drug abuse, and for the investigation of the mechanism of drug incorporation into hairPrincipal Investigator
- Principal Investigator
  
  TSUCHIHASHI Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka Medical College

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Fatal intoxication by 5F-ADB and diphenidine: Detection, quantification, and investigation of their main metabolic pathways in humans by LC/MS/MS and LC/Q-TOFMS2018
- Author(s)
  Kusano Maiko、Zaitsu Kei、Taki Kentaro、Hisatsune Kazuaki、Nakajima Jun'ichi、Moriyasu Takako、Asano Tomomi、Hayashi Yumi、Tsuchihashi Hitoshi、Ishii Akira
- Journal Title
  
  Drug Testing and Analysis
  
  Volume: 10 Issue: 2 Pages: 284-293
- DOI
  10.1002/dta.2215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02530, KAKENHI-PROJECT-18H03064, KAKENHI-PROJECT-20K20372
[Journal Article] In Vivo Real-Time Monitoring System Using Probe Electrospray Ionization/Tandem Mass Spectrometry for Metabolites in Mouse Brain2018
- Author(s)
  Zaitsu Kei、Hayashi Yumi、Murata Tasuku、Yokota Kazumi、Ohara Tomomi、Kusano Maiko、Tsuchihashi Hitoshi、Ishikawa Tetsuya、Ishii Akira、Ogata Koretsugu、Tanihata Hiroshi
- Journal Title
  
  Analytical Chemistry
  
  Volume: 90 Issue: 7 Pages: 4695-4701
- DOI
  10.1021/acs.analchem.7b05291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02530, KAKENHI-PROJECT-16K19271, KAKENHI-PROJECT-18H03064, KAKENHI-PROJECT-16K09354
[Journal Article] Intact metabolite profiling of mouse brain by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its potential use for local distribution analysis of the brain2017
- Author(s)
  Hayashi Yumi、Zaitsu Kei、Murata Tasuku、Ohara Tomomi、Moreau St?phane、Kusano Maiko、Tanihata Hiroshi、Tsuchihashi Hitoshi、Ishii Akira、Ishikawa Tetsuya
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 983 Pages: 160-165
- DOI
  10.1016/j.aca.2017.06.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09354, KAKENHI-PROJECT-15H02530, KAKENHI-PROJECT-16K19271
[Journal Article] Regioisomeric differentiation of the alkyl-substituted synthetic cannabinoids JWH-122 and JWH-210 by GC-EI-MS/MS2016
- Author(s)
  Kusano M, Yamanaka M, Zaitsu K, Nakayama H, Nakajima J-i, Moriyasu T, Tsuchihashi H, Ishii A
- Journal Title
  
  Forensic Toxicology
  
  Volume: 34 Issue: 2 Pages: 304-315
- DOI
  10.1007/s11419-016-0317-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02530, KAKENHI-PROJECT-26893105, KAKENHI-PROJECT-15K19272
[Journal Article] Development of a mass spectrometric hydroxyl-position determination method for the hydroxyindole metabolites of JWH-018 by GC-MS/MS2016
- Author(s)
  Kusano M, Zaitsu K, Yamanaka M, Hisatsune K, Asano T, Taki K, Hayashi Y, Tsuchihashi H, Ishii A
- Journal Title
  
  J Mass Spectrom
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02530
[Journal Article] Intact endogenous metabolite analysis of mice liver by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its preliminary application to in vivo real-time analysis2016
- Author(s)
  Kei Zaitsu*, Yumi Hayashi, Tasuku Murata, Tomomi Ohara, Kenta Nakagiri, Maiko Kusano, Hiroki Nakajima, Tamie Nakajima, Tetsuya Ishikawa, Hitoshi Tsuchihashi, Akira Ishii
- Journal Title
  
  Analytical Chemistry
  
  Volume: 88(7) Issue: 7 Pages: 3556-3561
- DOI
  10.1021/acs.analchem.5b04046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19272, KAKENHI-PROJECT-15H02530, KAKENHI-PROJECT-26860437
[Journal Article] GC/MS/MSの基礎と法中毒学への応用2016
- Author(s)
  草野麻衣子、財津桂、土橋均、石井晃
- Journal Title
  
  中毒研究
  
  Volume: 29 Pages: 387-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02530
[Journal Article] Application of metabolomics to toxicology of drugs of abuse: a mini review of metabolomics approach to acute and chronic toxicity studies2016
- Author(s)
  Kei Zaitsu*, Yumi Hayashi, Maiko Kusano, Hitoshi Tsuchihashi, Akira Ishii.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 31 Issue: 1 Pages: 21-26
- DOI
  10.1016/j.dmpk.2015.10.002
- NAID
  50014431237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19272, KAKENHI-PROJECT-15H02530
[Journal Article] A preliminary study on postmortem interval estimation of suffocating rats by GC-MS/MS-based plasma metabolic profiling2015
- Author(s)
  T Sato, K Zaitsu, K Tsuboi, M Nomura, M Kusano, N Shima, S Abe, A Ishii, H Tsuchihashi, K Suzuki
- Journal Title
  
  Analytical Bioanalytical Chemistry
  
  Volume: in press Issue: 13 Pages: 3659-3665
- DOI
  10.1007/s00216-015-8584-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659337, KAKENHI-PROJECT-25460880
[Journal Article] Time-Course Mass Spectrometry Imaging for Depicting Drug Incorporation into Hair2015
- Author(s)
  Tooru Kamata, Noriaki Shima, Keiko Sasaki, Shuntaro Matsuta, Shiori Takei, Munehiro Katagi, Akihiro Miki, Kei Zaitsu, Toyofumi Nakanishi, Takako Sato, Koichi Suzuki, and Hitoshi Tsuchihashi
- Journal Title
  
  Analytical Chemistry (ACS Publications)
  
  Volume: - Issue: 11 Pages: 5476-5481
- DOI
  10.1021/acs.analchem.5b00971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590065, KAKENHI-PROJECT-25513010
[Journal Article] Metabolome disruption of the rat cerebrum induced by the acute toxic effects of the synthetic cannabinoid MAM-2201.2015
- Author(s)
  Zaitsu K, Hayashi Y, Suzuki K, Nakayama H, Hattori N, Takahara R, Kusano M, Tsuchihashi H, Ishii A.
- Journal Title
  
  Life Sci
  
  Volume: 137 Pages: 49-55
- DOI
  10.1016/j.lfs.2015.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02530
[Journal Article] High-resolution mass spectrometric determination of the synthetic cannabinoids MAM-2201, AM-2201, AM-2232, and their metabolites in postmortem plasma and urine by LC/Q-TOFMS2015
- Author(s)
  Zaitsu K, Nakayama H, Yamanaka M, Hisatsune K, Taki K, Asano T, Kamata T, Katagai M, Hayashi Y, Kusano M, Tsuchihashi H, Ishii A.
- Journal Title
  
  Int J Legal Med
  
  Volume: 129 Issue: 6 Pages: 1233-1245
- DOI
  10.1007/s00414-015-1257-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02530
[Journal Article] Metabolism of the designer drug α-pyrrolidinobutiophenone (α-PBP) in humans: identification and quantification of the phase I metabolites in urine.2015
- Author(s)
  Matsuta S, Shima N, Kamata H, Kakehashi H, Nakano S, Sasaki K, Kamata T, Nishioka H, Miki A, Katagi M, Zaitsu K, Sato T, Tsuchihashi H, Suzuki K.
- Journal Title
  
  Forensic Sci Int
  
  Volume: 249 Pages: 181-188
- DOI
  10.1016/j.forsciint.2015.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02530
[Journal Article] 毛髪の質量分析イメージングで探る薬物使用歴2013
- Author(s)
  三木昭宏　土橋均　等
- Journal Title
  
  臨床化学
  
  Volume: 42 Pages: 311316-311316
- Data Source
  KAKENHI-PROJECT-24590065
[Presentation] Relative abundances of 5F-ADB and its ester hydrolysis metabolite in carboxylesterase-containing tissue specimens.2018
- Author(s)
  Maiko Kusano, Kei Zaitsu, Kazuaki Hisatsune, Atsushi Ishiba, Minemasa Hida, Jun’ichi Nakajima, Jin Suzuki, Takako Moriyasu, Hitoshi Tsuchihashi, Akira Ishii.
- Organizer
  SOFT-TIAFT 5th Joint Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Analyses of plasma metabolomics in combination use of psychotropic drugs in rats2018
- Author(s)
  Sato T, Tsuboi K, Nomura M, Matsumoto T, Zaitsu K, Shima N, Kitagawa M, Saito T, Abe S, Tsuchihashi H, Suzuki K
- Organizer
  24th Congress of the International Academy of Legal Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08890
[Presentation] High-throughput intact metabolome analysis of mouse biological specimens by probe electrospray ionization/tandem mass spectrometry (PESI/MS/MS).2017
- Author(s)
  Yumi Hayashi, Kei Zaitsu, Tasuku Murata, Shiono Baba, Tomomi Ohara, Stephane Moreau, Maiko Kusano, Hiroki Nakajima, Hiroshi Tanihata, Hitoshi Tsuchihashi, Akira Ishii, Tetsuya Ishikawa.
- Organizer
  65th ASMS conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Analyses of plasma metabolomics after administration of psychotropic drugs in rats2017
- Author(s)
  Sato T, Tsuboi K, Nomura M, Matsumoto T, Zaitsu K, Shima N, Kitagawa M, Saito T, Abe S, Tsuchihashi H, Suzuki K
- Organizer
  10th International Symposium Advances in Legal Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08890
[Presentation] 急激な転帰をたどった心筋炎の一例.2017
- Author(s)
  石井晃、吉本高士、伊藤雅文、山本敏充、財津桂、草野麻衣子、土橋均.
- Organizer
  第101次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Direct drug analysis in serum by probe electrospray ionization/tandem mass spectrometry and its preliminary application to a real-time metabolism study.2017
- Author(s)
  Kei Zaitsu, Yumi Hayashi, Maiko Kusano, Kazuaki Hisatsune , Tomomi Ohara, Tasuku Murata, Hiroki Nakajima, Hiroshi Tanihata, Hitoshi Tsuchihashi, Tetsuya Ishikawa, Akira Ishii.
- Organizer
  MSACL-US 2017 9th Annual Conference & Exhibits
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] PESI/MS/MSを用いたin vivoリアルタイム・メタボライト分析法の構築2017
- Author(s)
  財津桂、林由美、村田匡、横田佳澄、土橋均、石井晃、緒方是嗣、谷畑博司
- Organizer
  第11回メタボローム・シンポジウム
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 臓器中5F-ADB濃度と加水分解酵素の相関及び体内分布．2017
- Author(s)
  草野麻衣子、財津桂、大原倫美、野田沙樹、久恒一晃、浅野友美、吉本高士、中嶋順一、鈴木仁、守安貴子、土橋均、石井晃．
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Development of an In Vivo Real-time Monitoring System using Probe Electrospray Ionization/Tandem Mass Spectrometry (PESI/MS/MS) and its Preliminary Applications.2017
- Author(s)
  Kei Zaitsu, Yumi Hayashi, Tasuku Murata, Tomomi Ohara, Stephane Moreau, Maiko Kusano, Hiroki Nakajima, Hiroshi Tanihata, Hitoshi Tsuchihashi, Tetsuya Ishikawa, Akira Ishii.
- Organizer
  65th ASMS conference on Mass Spectrometry and Allied Topics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] The Direct Detection and Ultrafast Quantification of Drugs of Abuse in Serum by Probe Electrospray Ionization/Tandem Mass Spectrometry (PESI/MS/MS).2017
- Author(s)
  Maiko Kusano, Kei Zaitsu, Yumi Hayashi, Tasuku Murata, Hiroki Nakajima, Saki Noda, Hitoshi Tsuchihashi, Akira Ishii.
- Organizer
  American Academy of Forensic Sciences (AAFS) 69th Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Rapid-fire direct metabolome analysis by probe electrospray ionization/tandem mass spectrometry: its preclinical applications to validate the methods.2017
- Author(s)
  Yumi Hayashi, Kei Zaitsu, Tasuku Murata, Tomomi Ohara, Kenta Kondo, Maiko Kusano, Koretsugu Ogata, Hitoshi Tsuchihashi, Hiroshi Tanihata, Akira Ishii, Tetsuya Ishikawa.
- Organizer
  MSACL 2017 EU 4th Annual EU Congress & Exhibits
- Invited
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] メタボロミクス及び骨格筋UCP-3発現解析によるセロトニン症候群モデルラットの病態解析．2017
- Author(s)
  野田沙樹、財津桂、林由美、大原倫美、井口亮、草野麻衣子、佐藤貴子、土橋均、石川哲也、鈴木廣一、石井晃.
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Quick/DB-GC/MS/MS法を用いたヒト血中薬毒物の高感度分析の検討.2017
- Author(s)
  李暁鵬、藤城雅也、長谷川智華、根本紀子、草野麻衣子、財津桂、土橋均、石井晃、熊澤武志、佐藤啓造．
- Organizer
  第101次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] nano-flow injection ESI/Q-TOFMSによるハイスループット・メタボローム分析法の構築2017
- Author(s)
  瀧健太朗、財津桂、林由美、大原倫美、野田沙樹、土橋均、石井晃
- Organizer
  第42回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] nano LC/MS/MSを用いた胆汁酸一斉定量分析法の構築とNASHモデルラット肝臓試料への応用．2017
- Author(s)
  浅野友美、財津桂、瀧健太朗、北森一哉、内藤久雄、那須民江、土橋均、石井晃．
- Organizer
  第42回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] セロトニン症候群モデルラットにおける筋肉の異常収縮と血漿メタボローム・プロファイルの関連性.2017
- Author(s)
  財津桂、野田沙樹、林由美、大原倫美、井口亮、草野麻衣子、佐藤貴子、土橋均、石川哲也、鈴木廣一、石井晃.
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Direct and rapid analysis of drugs in serum by probe electrospray ionization tandem mass spectrometry (PESI/MS/MS).2017
- Author(s)
  Tomomi Ohara, Kei Zaitsu, Yumi Hayashi, Maiko Kusano, Kazuaki Hisatsune, Tasuku Murata, Stephane Moreau ,Hiroki Nakajima, Hiroshi Tanihata, Hitoshi Tsuchihashi, Tetsuya Ishikawa, Akira Ishii.
- Organizer
  15th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 探針エレクトロスプレータンデム質量分析(PESI/MS/MS)を用いた超迅速かつ簡便な血液中薬毒物スクリーニング法の構築.2017
- Author(s)
  久恒一晃、財津桂、林由美、村田匡、大原倫美、草野麻衣子、谷畑博司、肥田宗政、土橋均、石川哲也、石井晃.
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] The Direct Detection and Ultrafast Quantification of Drugs of Abuse in Serum by Probe Electrospray Ionization/Tandem Mass Spectrometry (PESI/MS/MS)2017
- Author(s)
  Maiko Kusano, Kei Zaitsu, Yumi Hayashi, Tasuku Murata, Hiroki Nakajima, Saki Noda, Hitoshi Tsuchihashi, Akira Ishii
- Organizer
  American Academy of Forensic Sciences (AAFS) 69th Annual Scientific Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2017-02-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] PESI/MS/MSを用いたインタクト・メタボローム分析法の構築2017
- Author(s)
  林由美、財津桂、村田匡、大原倫美、近藤健太、石川哲也、土橋均、石井晃、緒方是嗣、谷畑博司
- Organizer
  第11回メタボローム・シンポジウム
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 自動前処理装置「ATLAS-USIS」とGC/MSを用いた血中薬毒物の全自動スクリーニング法の構築．2017
- Author(s)
  中山佳奈、草野麻衣子、財津桂、野田沙樹、大原倫美、片木宗弘、三木昭宏、土橋均、石井晃．
- Organizer
  第101次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Direct drug analysis in serum by probe electrospray ionization/tandem mass spectrometry and its preliminary application to a real-time metabolism study2017
- Author(s)
  Kei Zaitsu, Yumi Hayashi, Maiko Kusano, Kazuaki Hisatsune , Tomomi Ohara, Tasuku Murata, Hiroki Nakajima, Hiroshi Tanihata, Hitoshi Tsuchihashi, Tetsuya Ishikawa, Akira Ishii
- Organizer
  MSACL-US 2017 9th Annual Conference & Exhibits
- Place of Presentation
  Palm Springs, CA, USA
- Year and Date
  2017-01-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 探針エレクトロスプレータンデム質量分析（PESI/MS/MS）を用いた超迅速かつ簡便な血清中薬物分析法の構築2016
- Author(s)
  久恒一晃、財津桂、草野麻衣子、林由美、村田匡、中島宏樹、肥田宗政、土橋均、石井晃
- Organizer
  日本法科学技術学会第22回学術集会
- Place of Presentation
  中野サンプラザ、東京都、中野区
- Year and Date
  2016-11-10
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] nano-flow injection ESI/Q-TOFMSによる迅速メタボローム分析法の検討2016
- Author(s)
  瀧健太朗、財津桂、林由美、浅野友美、草野麻衣子、土橋均、石井晃
- Organizer
  第41回日本医用マススペクトル学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] nano LC/MS/MSによる胆汁酸一斉分析方法のラット肝臓試料への応用2016
- Author(s)
  浅野友美、財津桂、瀧健太朗、草野麻衣子、北森一哉、内藤久雄、那須民江、土橋均、石井晃
- Organizer
  第41回日本医用マススペクトル学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] マウスを用いた合成カンナビノイドJWH-018およびAM-2201の胆汁排泄の評価.2016
- Author(s)
  久恒一晃、財津桂、林由美、瀧健太朗、浅野友美、石場厚、肥田宗政、草野麻衣子、土橋均、石井晃
- Organizer
  日本法中毒学会35年会
- Place of Presentation
  大阪産業創造館、大阪市、大阪府
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Real-time Monitoring of Glutamic Acid in Mouse Brain by Direct Coupling of Microdialysis to Tandem MS with the Newly Developed On-line Desalting System. The Association for Mass Spectrometry: Applications to the Clinical Lab (MSACL 2016 EU)2016
- Author(s)
  Kei Zaitsu, Yumi Hayashi, Hiroaki Kanayama, Ryosuke Takagi, Saki Noda, Maiko Kusano, Toshikazu Minohata , Jun-ichi Azuma, Nobuhiro Kanayama, Tetsuya Ishikawa, Hitoshi Tsuchihashi, Akira Ishii
- Organizer
  The Association Spectrometry:Applications to the Clinical Lab (MSACL 2016 EU)
- Place of Presentation
  Salzburg, Austria
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Ultrafast and direct detection of drugs of abuse in serum by probe electrospray ionization-tandem mass spectrometry (PESI-MS/MS)2016
- Author(s)
  Maiko Kusano, Kei Zaitsu, Yumi Hayashi, Saki Noda, Tomomi Ohara, Hitoshi Tsuchihashi, Akira Ishii
- Organizer
  The 54th Annual Meeting of the International Association of Forensic Toxicologists (TIAFT)
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2016-08-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Real-time metabolome analysis by probe electrospray ionization-tandem mass Spectrometry (PESI-MS/MS): preliminary challenge to real-time metabolomics2016
- Author(s)
  Kei Zaitsu, Yumi Hayashi, Tasuku Murata, Hiroki Nakajima, Tamie Nakajima, Maiko Kusano, Hitoshi Tsuchihashi, Tetsuya Ishikawa, Akira Ishii
- Organizer
  Pittcon Conference & EXPO 2016
- Place of Presentation
  Atlanta, GA, USA
- Year and Date
  2016-03-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] A fatal intoxication case of 5-Fluoro-ADB and diphenidine2016
- Author(s)
  Akira Ishii, Maiko Kusano, Kentaro Taki, Kazuaki Hisatsune, Hitoshi Tsuchihashi, Kei Zaitsu
- Organizer
  The 54th Annual Meeting of the International Association of Forensic Toxicologists (TIAFT)
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 危険ドラッグ使用による2死亡例2016
- Author(s)
  石井晃、伊藤雅文、久恒一晃、草野麻衣子、山中麻友美、吉本高士、土橋均、山本敏充、財津桂
- Organizer
  第100次日本法医学会学術全国集会
- Place of Presentation
  きゅりあん、東京都、品川区
- Year and Date
  2016-05-15
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Intact metabolome analysis of mice biological tissues by probe electrospray　　　　ionization-tandem mass spectrometry and its preliminary application to real-time analysis2016
- Author(s)
  Kei Zaitsu, Yumi Hayashi, Tasuku Murata, Hiroki Nakajima, Tetsuya Ishikawa, Maiko Kusano, Hitoshi 　　Tsuchihashi, Akira Ishii
- Organizer
  The 64th Conference of American Society for Mass Spectrometry
- Place of Presentation
  San Antonio, TX, USA
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 自動前処理装置「ATLAS-USIS」を用いた血中薬毒物の一斉定量分析法の開発2016
- Author(s)
  中根有登、草野麻衣子、山中麻由美、篠田諭、酒井佑一朗、片木宗弘、三木昭宏、土橋均、財津桂、石井晃
- Organizer
  第100次日本法医学会学術全国集会
- Place of Presentation
  きゅりあん、東京都、品川区
- Year and Date
  2016-05-15
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] nano-flow injection ESI/Q-TOFMSによる迅速メタボローム分析法の検討2016
- Author(s)
  瀧健太朗、財津桂、林由美、浅野友美、草野麻衣子、土橋均、石井晃
- Organizer
  日本質量分析学会第64回質量分析総合討論会
- Place of Presentation
  ホテル阪急エキスポパーク、吹田、大阪府
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] GC-MS/MSによるJWH-018 尿中代謝物の水酸基位置決定法の構築2016
- Author(s)
  草野麻衣子、財津桂、久恒一晃、浅野友美、瀧健太朗、林由美、土橋均、石井晃
- Organizer
  日本法中毒学会35年会
- Place of Presentation
  大阪産業創造館、大阪市、大阪府
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Application of Intact Metabolome Analysis by Probe Electrospray Ionization (PESI)/MS/MS to Local Distribution Analysis and in vivo Real-time Monitoring.2016
- Author(s)
  Yumi Hayashi, Kei Zaitsu, Tasuku Murata, Hiroki Nakajima, Maiko Kusano, Hitoshi Tsuchihashi, 　　Akira Ishii, Tetsuya Ishikawa
- Organizer
  The Association Spectrometry:Applications to the Clinical Lab (MSACL 2016 EU)
- Place of Presentation
  Salzburg, Austria
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Quantification of designer drugs 5-F-ADB and diphenidine in postmortem blood and investigation of their main metabolic pathway in human by LC/Q-TOFMS2016
- Author(s)
  Maiko Kusano, Kei Zaitsu, Kentaro Taki, Saki Noda, Tomomi Ohara, Kazuaki Hisatsune, Tomomi Asano, Yumi Hayashi, Hitoshi Tsuchihashi, Akira Ishii
- Organizer
  Society of Forensic Toxicologists (SOFT) 2016 ANNUAL MEETING
- Place of Presentation
  Dallas, TX, USA
- Year and Date
  2016-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 生体試料中薬毒物分析における自動前処理装置「ATLAS-USIS」の法医試料への応用2015
- Author(s)
  財津桂、草野麻衣子、山中麻友美、松田駿太朗、片木宗弘、三木昭宏、佐藤貴子、土橋均、鈴木廣一、石井晃
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化センター、高知県、高知市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Micro LC/MS/MSによる高感度自然毒一斉スクリーニング法の構築2015
- Author(s)
  瀧健太朗、財津桂、小川匡之、浅野友美、草野麻衣子、妹尾洋、土橋均、石井晃
- Organizer
  日本質量分析学会第63回質量分析総合討論会
- Place of Presentation
  エポカルつくば、茨城県、つくば市
- Year and Date
  2015-06-17
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] LC/Q-TOFMSによる急性中毒死者生体試料中α-PHPおよびアセチルフェンタニルの分析2015
- Author(s)
  久恒一晃、財津桂、草野麻衣子、山中麻友美、中嶋順一、守安貴子, 石場厚、肥田宗政、土橋均、石井晃
- Organizer
  日本法中毒学会第34年会
- Place of Presentation
  九州大学医学部百年講堂、福岡県、福岡市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] ラット熱中症モデルにおけるメタボロミクス解析2015
- Author(s)
  佐藤貴子、財津桂、坪井健人、野村和克、岩田美佐、志摩典明、阿部俊太郎、石井晃、土橋均、鈴木廣一
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化センター、高知県、高知市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] GC/MS/MSによる合成カンナビノイドJWH-122およびJWH-210の位置異性体識別の検討2015
- Author(s)
  山中麻友美、財津桂、草野麻衣子、久恒一晃、中嶋順一、守安貴子、松田駿太朗、片木宗弘、土橋均、石井晃
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化センター、高知県、高知市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] GC-MS/MSを用いた包括指定カチノン類の一斉検出と構造推定 (第2報)2015
- Author(s)
  坂本雄紀、宮川治彦、松田駿太朗、鎌田徹、西岡裕、片木宗弘、草野麻衣子、財津桂、土橋均
- Organizer
  第21回日本法科学技術学会
- Place of Presentation
  柏の葉カンファレンスセンター、千葉県、柏市
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Development and validation for a highly sensitive GC-MS/MS screening and quantification method of forensically relevant drugs of abuse in whole blood2015
- Author(s)
  Maiko Kusano, Kei Zaitsu, Yuki Sakamoto, Haruhiko Miyagawa, Hitoshi Tsuchihashi, Akira Ishii
- Organizer
  The 53rd Annual Meeting of the International Association of Forensic Toxicologists
- Place of Presentation
  Florence, Italy
- Year and Date
  2015-08-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] GC/MS/MSによる血中薬毒物の高感度定量分析法の開発2015
- Author(s)
  草野麻衣子、財津桂、坂本雄紀、宮川治彦、土橋均、石井晃
- Organizer
  日本法中毒学会第34年会
- Place of Presentation
  九州大学医学部百年講堂、福岡県、福岡市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] Determination of newly encountered designer drugs α-PHP and acetylfentanyl in an acute intoxication case by LC/Q-TOFMS2015
- Author(s)
  Kazuaki Hisatsune, Kei Zaitsu, Maiko Kusano, Mayumi Yamanaka, Jun’ichi　Nakajima, Takako Moriyasu, Atsushi Ishiba, Minemasa Hida, Hitoshi Tsuchihashi, Akira Ishii
- Organizer
  The 53rd Annual Meeting of the International Association of Forensic Toxicologists
- Place of Presentation
  Florence, Italy
- Year and Date
  2015-08-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02530
[Presentation] 質量分析イメージングによる毛髪中薬物の分析2014
- Author(s)
  三木昭宏, 鎌田徹, 志摩典明, 片木宗弘, 中西豊文, 土橋均
- Organizer
  日本法中毒学会第33年会　シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-24590065
[Presentation] イメージング質量分析による毛髪中メトキシフェナミンの画像化2013
- Author(s)
  鎌田徹　土橋均　等
- Organizer
  日本法中毒学会第32年会
- Place of Presentation
  千葉県柏市　さわやかちば県民プラザ
- Data Source
  KAKENHI-PROJECT-24590065
[Presentation] Hair Analysis for Drugs by Mass Spectrometry Imaging : A New Perspective to Investigate Drug Use History.2013
- Author(s)
  三木昭宏　土橋均　等
- Organizer
  TIAFT 2013
- Place of Presentation
  ポルトガル（フンシャル）
- Data Source
  KAKENHI-PROJECT-24590065
[Presentation] Postmortem interval estimation of suffocated rats by plasma metabolic profiling
- Author(s)
  Sato T, Zaitsu K, Tsuboi K, Nomura M, Shima N, Iwata M, Abe S, Ishii A, Tsuchihashi H, Suzuki K
- Organizer
  the 9th International Symposium on Advances in Legal Medicine
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2014-06-16 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25460880
[Presentation] Imaging Hair Analyses for Drugs:A New Perspective to Investigate Drug Use History.
- Author(s)
  鎌田　徹　土橋　均　等
- Organizer
  第19回　国際質量分析学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-24590065
[Presentation] ラット熱中症モデルにおけるメタボロミクス解析
- Author(s)
  佐藤貴子、財津　桂、坪井健人、野村和克、岩田美佐、志摩典明、阿部俊太郎、石井晃、土橋　均、鈴木廣一
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化プラザかるぽーと
- Year and Date
  2015-06-10 – 2015-06-12
- Data Source
  KAKENHI-PROJECT-25460880
[Presentation] イメージング質量分析による毛髪試料中薬物の検出
- Author(s)
  鎌田　徹　土橋　均　等
- Organizer
  日本法科学技術学会　第１８回学術集会
- Place of Presentation
  ホテルフロラシオン青山（東京）
- Data Source
  KAKENHI-PROJECT-24590065

1. SATO Takako (10530420)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. 財津桂 (30700546)

# of Collaborated Projects: 3 results

# of Collaborated Products: 58 results
3. Suzuki Koichi (60171211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAKANISHI Toyofumi (10247843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Ishii Akira (30252175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 51 results
6. 那須民江 (10020794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
7. 林由美 (30632707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
8. 妹尾洋 (50236113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 小川匡之 (50559937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 草野麻衣子 (60733574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 46 results
11. 内藤久雄 (90547556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. MIKI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. KAMATA Tooru

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. SHIMA Noriaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. KATAGI Munehiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. HISATSUNE KAZUAKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
17. NAKAJIMA JUN'ICHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
18. ITO Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 鈴木広一

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
20. 石川哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TSUCHIHASHI Hitoshi 土橋 均

Research Projects

Research Products

Co-Researchers

Pathophysiological analysis of sudden death related with polypharmacy by metabolomics analysis and it's application to forensic diagnosis

Principal Investigator

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Application of novel mass spectrometric techniques for highly sensitive, specific and speedy identification of new psychoactive substances in human specimens

Principal Investigator

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Research Institution

Forensic diagnosis for heatstroke-a search for useful biomarkers by metabolic profiling

Principal Investigator

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Research Institution

Mass spectrometry imaging of single hair specimens for the reliable chronological estimation of drug abuse, and for the investigation of the mechanism of drug incorporation into hairPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Fatal intoxication by 5F-ADB and diphenidine: Detection, quantification, and investigation of their main metabolic pathways in humans by LC/MS/MS and LC/Q-TOFMS2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In Vivo Real-Time Monitoring System Using Probe Electrospray Ionization/Tandem Mass Spectrometry for Metabolites in Mouse Brain2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intact metabolite profiling of mouse brain by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its potential use for local distribution analysis of the brain2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regioisomeric differentiation of the alkyl-substituted synthetic cannabinoids JWH-122 and JWH-210 by GC-EI-MS/MS2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a mass spectrometric hydroxyl-position determination method for the hydroxyindole metabolites of JWH-018 by GC-MS/MS2016

Author(s)

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Data Source

[Journal Article] Intact endogenous metabolite analysis of mice liver by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its preliminary application to in vivo real-time analysis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GC/MS/MSの基礎と法中毒学への応用2016

Author(s)

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Data Source

[Journal Article] Application of metabolomics to toxicology of drugs of abuse: a mini review of metabolomics approach to acute and chronic toxicity studies2016

Author(s)

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DOI

NAID

Data Source

[Journal Article] A preliminary study on postmortem interval estimation of suffocating rats by GC-MS/MS-based plasma metabolic profiling2015

Author(s)

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Data Source

[Journal Article] Time-Course Mass Spectrometry Imaging for Depicting Drug Incorporation into Hair2015

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Data Source

[Journal Article] Metabolome disruption of the rat cerebrum induced by the acute toxic effects of the synthetic cannabinoid MAM-2201.2015

Author(s)

Journal Title

TSUCHIHASHI Hitoshi 土橋均