Komatsu Toru 小松徹

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KOMATSU Toru 小松徹

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Researcher Number	40599172
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院薬学系研究科(薬学部), 准教授
Affiliation (based on the past Project Information) *help	2025: 東京大学, 大学院薬学系研究科(薬学部), 准教授 2021 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 助教 2017 – 2020: 東京大学, 大学院薬学系研究科(薬学部), 特任助教 2016: 東京大学, 大学院薬学系研究科(薬学部), 助教 2015: 東京大学, 薬学研究科(研究院), 助教 … More 2013 – 2014: 東京大学, 大学院薬学系研究科, 助教 2012 – 2013: 東京大学, 薬学研究科(研究院), 助教 2011: 東京大学, 大学院・薬学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Science and Engineering / Pharmaceutical Sciences and related fields / Chemical biology / Physical pharmacy / Chemistry related to living body Except Principal Investigator Transformative Research Areas, Section (III) / Chemistry / Science and Engineering
Keywords	Principal Investigator ケミカルバイオロジー / 創薬化学 / 酵素 / 生化学 / 分子夾雑 / enzymomics Except Principal Investigator 分析科学 / 有機化学 / 蛍光プローブ / ハイスループットスクリーニング … More / 硫化水素 / 超硫黄分子 / NMRプローブ / 酵素阻害剤 / 光化学 / イメージング / 薬学 / 有機光化学 / 化合物スクリーニング / 臨床診断 / MRI造影剤 / 光増感剤 / 分子イメージング / ケミカルバイオロジー / 生体機能関連化学 Less

ケミカルプローブの全自動合成に基づく enzymomics 研究の高度化Principal Investigator
- Principal Investigator
  
  小松徹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  The University of Tokyo
Development of enzymomics platform for characterization of disease-related alterations of enzymatic activitiesPrincipal Investigator
- Principal Investigator
  
  小松徹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  The University of Tokyo
Development of chemical tools for multimodal imaging of supersulfides and manipulation of their biosynthesis
- Principal Investigator
  
  花岡健二郎
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Keio University
Development of synthetic biological tools to modify metabolic fates of cellsPrincipal Investigator
- Principal Investigator
  
  小松徹
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Establishment of enzymomics platform for discovery of disease-related protein functionsPrincipal Investigator
- Principal Investigator
  
  Komatsu Toru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  The University of Tokyo
Development of on-organelle protein trapping method to study the meanings of transient organelle localization of tumor-associated proteinsPrincipal Investigator
- Principal Investigator
  
  小松徹
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Development of coupled assay-based fluorescent probes to monitor post-translational modification reactions in live cellsPrincipal Investigator
- Principal Investigator
  
  Komatsu Toru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  The University of Tokyo
Development of chemical biological tools to monitor and control pathologically important methyltransferase activitesPrincipal Investigator
- Principal Investigator
  
  Komatsu Toru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
Development of synthetic biological tools for modulating metabolic fates of cellsPrincipal Investigator
- Principal Investigator
  
  Komatsu Toru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
Development of chromophore-assisted laser scarring method for characterization of drug target proteinsPrincipal Investigator
- Principal Investigator
  
  KOMATSU Toru
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo
Development of synthetic photo-functional molecules for medical applications
- Principal Investigator
  
  NAGANO Tetsuo
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  The University of Tokyo

[Book] 疾患と関わる酵素の働きを夾雑環境下で「視る」2023
- Author(s)
  小松徹
- Total Pages
  208
- Publisher
  化学同人
- ISBN
  9784759814057
- Data Source
  KAKENHI-PROJECT-23K23484
[Book] 茶カテキンによるエピジェネティック制御因子への関与2022
- Author(s)
  小松徹，小倉大輝，浦野泰照
- Total Pages
  333
- Publisher
  シーエムシー出版
- ISBN
  9784781316871
- Data Source
  KAKENHI-PROJECT-23K23484
[Book] 酵素のはたらきを見て疾患を知る～Activity-based diagnosticsの最新動向～2021
- Author(s)
  小松徹, 坂本眞伍, 鏡味優, 浦野泰照
- Total Pages
  4
- Publisher
  月刊「細胞」
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Book] 酵素のはたらきを見て疾患を知る～Activity-based diagnosticsの最新動向～2021
- Author(s)
  小松徹, 坂本眞伍, 鏡味優, 浦野泰照
- Total Pages
  4
- Publisher
  月刊「細胞」
- Data Source
  KAKENHI-PROJECT-19H02846
[Book] (+)-カテキンを介した大腸がん細胞のヒストンメチル化の減少2020
- Author(s)
  荻原洲介，小松徹，浦野泰照
- Total Pages
  3
- Publisher
  一般財団法人バイオインダストリー協会
- Data Source
  KAKENHI-PROJECT-19H02846
[Book] 1分子計測リキッドバイオプシーの夜明け2020
- Author(s)
  小松徹，坂本眞伍，浦野泰照
- Total Pages
  6
- Publisher
  日本プロテオーム学会
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Book] (+)-カテキンを介した大腸がん細胞のヒストンメチル化の減少2020
- Author(s)
  荻原洲介，小松徹，浦野泰照
- Total Pages
  3
- Publisher
  一般財団法人バイオインダストリー協会
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Book] 1分子計測リキッドバイオプシーの夜明け2020
- Author(s)
  小松徹，坂本眞伍，浦野泰照
- Total Pages
  6
- Publisher
  日本プロテオーム学会
- Data Source
  KAKENHI-PROJECT-19H02846
[Book] 酵素のはたきを「見る」ケミカルバイオロジー研究／科学のとびら 60 「天然物の化学 - 魅力と展望」2016
- Author(s)
  小松徹、浦野泰照
- Total Pages
  200
- Publisher
  株式会社東京化学同人
- Data Source
  KAKENHI-PROJECT-15K14937
[Book] 酵素のはたきを「見る」ケミカルバイオロジー研究／科学のとびら 60 「天然物の化学 - 魅力と展望」2016
- Author(s)
  小松徹、浦野泰照
- Total Pages
  200
- Publisher
  株式会社東京化学同人
- Data Source
  KAKENHI-PROJECT-15H05371
[Book] 「表現型アッセイ①:アカデミア創薬における創薬標的タンパク質の探索研究」実験医学2014年1月増刊号『研究成果を薬につなげるアカデミア創薬の戦略と実例』2014
- Author(s)
  小松徹
- Data Source
  KAKENHI-PROJECT-24655147
[Book] 実験医学2014年1月増刊号『アカデミア発新薬の実現に向けた創薬研究［総集編］』2014
- Author(s)
  小松徹
- Total Pages
  10
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Identification of activity-based biomarkers for early-stage pancreatic tumors in blood using single-molecule enzyme activity screening2024
- Author(s)
  Shingo Sakamoto、Hideto Hiraide、Mayano Minoda、Nozomi Iwakura、Misa Suzuki、Jun Ando、Chiharu Takahashi、Ikuko Takahashi、Kazue Murai、Yu Kagami、Tadahaya Mizuno、Tohru Koike、Satoshi Nara、Chigusa Morizane、Susumu Hijioka、Ayumi Kashiro、Kazufumi Honda、Rikiya Watanabe、Yasuteru Urano、Toru Komatsu
- Journal Title
  
  Cell Reports Methods
  
  Volume: 4 Issue: 1 Pages: 100688-100688
- DOI
  10.1016/j.crmeth.2023.100688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K23484
[Journal Article] A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT)2024
- Author(s)
  Hanaoka Kenjiro、Ikeno Takayuki、Iwaki Shimpei、Deguchi Sayaka、Takayama Kazuo、Mizuguchi Hiroyuki、Tao Fumiya、Kojima Nobuhiko、Ohno Hisashi、Sasaki Eita、Komatsu Toru、Ueno Tasuku、Maeda Kazuya、Kusuhara Hiroyuki、Urano Yasuteru
- Journal Title
  
  Science Advances
  
  Volume: 10 Issue: 7
- DOI
  10.1126/sciadv.adi8847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-23K23484, KAKENHI-PROJECT-23K27304, KAKENHI-PROJECT-23K27337
[Journal Article] Thioester‐Based Coupled Fluorogenic Assays in Microdevice for the Detection of Single‐Molecule Enzyme Activities of Esterases with Specified Substrate Recognition2023
- Author(s)
  Ukegawa Tatsuya、Komatsu Toru、Minoda Mayano、Matsumoto Takuya、Iwasaka Takumi、Mizuno Tadahaya、Tachibana Ryo、Sakamoto Shingo、Hanaoka Kenjiro、Kusuhara Hiroyuki、Honda Kazufumi、Watanabe Rikiya、Urano Yasuteru
- Journal Title
  
  Advanced Science
  
  Volume: 11 Issue: 10 Pages: 2306559-2306559
- DOI
  10.1002/advs.202306559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-23K23484, KAKENHI-PROJECT-23K27304
[Journal Article] Development of pathway-oriented screening to identify compounds to control 2-methylglyoxal metabolism in tumor cells2023
- Author(s)
  Yanagi Kouichi、Komatsu Toru、Fujikawa Yuuta、Kojima Hirotatsu、Okabe Takayoshi、Nagano Tetsuo、Ueno Tasuku、Hanaoka Kenjiro、Urano Yasuteru
- Journal Title
  
  Communications Chemistry
  
  Volume: 6 Issue: 1 Pages: 68-68
- DOI
  10.1038/s42004-023-00864-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02701, KAKENHI-PROJECT-23K23484, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-23K27304
[Journal Article] Modular Design Platform for Activatable Fluorescence Probes Targeting Carboxypeptidases Based on ProTide Chemistry2023
- Author(s)
  Kuriki Yugo、Sogawa Mari、Komatsu Toru、Kawatani Minoru、Fujioka Hiroyoshi、Fujita Kyohhei、Ueno Tasuku、Hanaoka Kenjiro、Kojima Ryosuke、Hino Rumi、Ueo Hiroki、Ueo Hiroaki、Kamiya Mako、Urano Yasuteru
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 146 Issue: 1 Pages: 521-531
- DOI
  10.1021/jacs.3c10086
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-23K23460, KAKENHI-PROJECT-23K23484, KAKENHI-PROJECT-23K27304
[Journal Article] Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation2023
- Author(s)
  Echizen Honami、Hanaoka Kenjiro、Shimamoto Kazuhito、Hibi Ryota、Toma-Fukai Sachiko、Ohno Hisashi、Sasaki Eita、Komatsu Toru、Ueno Tasuku、Tsuchiya Yukihiro、Watanabe Yasuo、Otsuka Takao、Saito Hiroaki、Nagatoishi Satoru、Tsumoto Kouhei、Kojima Hirotatsu、Okabe Takayoshi、Shimizu Toshiyuki、Urano Yasuteru
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 16456-16456
- DOI
  10.1038/s41598-023-43536-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05378, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-23K27304
[Journal Article] Molecular design of near-infrared (NIR) fluorescent probes targeting exopeptidase and application for detection of dipeptidyl peptidase 4 (DPP-4) activity2022
- Author(s)
  Hoshino Yuki、Hanaoka Kenjiro、Sakamoto Kei、Yasunaga Masahiro、Kojima Takashi、Kotani Daisuke、Nomoto Ayumu、Sasaki Eita、Komatsu Toru、Ueno Tasuku、Takamaru Hiroyuki、Saito Yutaka、Seto Yasuyuki、Urano Yasuteru
- Journal Title
  
  RSC Chemical Biology
  
  Volume: - Issue: 7 Pages: 859-867
- DOI
  10.1039/d1cb00253h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05262, KAKENHI-ORGANIZER-21H05258, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-23K23484
[Journal Article] Development of a fluorescent probe library enabling efficient screening of tumour-imaging probes based on discovery of biomarker enzymatic activities2022
- Author(s)
  Kuriki Yugo、Yoshioka Takafusa、Kamiya Mako、Komatsu Toru、Takamaru Hiroyuki、Fujita Kyohhei、Iwaki Hirohisa、Nanjo Aika、Akagi Yuki、Takeshita Kohei、Hino Haruaki、Hino Rumi、Kojima Ryosuke、Ueno Tasuku、Hanaoka Kenjiro、Abe Seiichiro、Saito Yutaka、Nakajima Jun、Urano Yasuteru
- Journal Title
  
  Chemical Science
  
  Volume: 13 Issue: 16 Pages: 4474-4481
- DOI
  10.1039/d1sc06889j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-19H02826, KAKENHI-PROJECT-20H02701, KAKENHI-PROJECT-20H02874, KAKENHI-PROJECT-21K08586, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-22KJ1177, KAKENHI-PROJECT-23K23484
[Journal Article] Rapid imaging of lung cancer using a red fluorescent probe to detect dipeptidyl peptidase 4 and puromycin-sensitive aminopeptidase activities2022
- Author(s)
  Kawashima Shun、Yoshida Daisuke、Yoshioka Takafusa、Ogasawara Akira、Fujita Kyohhei、Yanagiya Masahiro、Nagano Masaaki、Konoeda Chihiro、Hino Haruaki、Kitano Kentaro、Sato Masaaki、Hino Rumi、Kojima Ryosuke、Komatsu Toru、Kamiya Mako、Urano Yasuteru、Nakajima Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 12665-9
- DOI
  10.1038/s41598-022-12665-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08586, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-20H02874, KAKENHI-PROJECT-23K23460, KAKENHI-PROJECT-23K23484
[Journal Article] General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process2022
- Author(s)
  Hanaoka Kenjiro、Iwaki Shimpei、Yagi Kiyoshi、Myochin Takuya、Ikeno Takayuki、Ohno Hisashi、Sasaki Eita、Komatsu Toru、Ueno Tasuku、Uchigashima Motokazu、Mikuni Takayasu、Tainaka Kazuki、Tahara Shinya、Takeuchi Satoshi、Tahara Tahei、Uchiyama Masanobu、Nagano Tetsuo、Urano Yasuteru
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 43 Pages: 19778-19790
- DOI
  10.1021/jacs.2c06397
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19355, KAKENHI-ORGANIZER-20H05914, KAKENHI-PLANNED-20H05918, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PLANNED-22H05125, KAKENHI-PUBLICLY-22H05491, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H00889, KAKENHI-PROJECT-22H00320, KAKENHI-PROJECT-20H02701, KAKENHI-PROJECT-20H03337, KAKENHI-PROJECT-20H03349, KAKENHI-PROJECT-21F21113, KAKENHI-PUBLICLY-21H00188, KAKENHI-PROJECT-23K23484, KAKENHI-PROJECT-23K24198
[Journal Article] MITOL promotes cell survival by degrading Parkin during mitophagy2021
- Author(s)
  Shiiba Isshin、Takeda Keisuke、Nagashima Shun、Ito Naoki、Tokuyama Takeshi、Yamashita Shun‐Ichi、Kanki Tomotake、Komatsu Toru、Urano Yasuteru、Fujikawa Yuuta、Inatome Ryoko、Yanagi Shigeru
- Journal Title
  
  EMBO reports
  
  Volume: 22 Issue: 3
- DOI
  10.15252/embr.201949097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22419, KAKENHI-PLANNED-19H05712, KAKENHI-PUBLICLY-20H04694, KAKENHI-PUBLICLY-20H04911, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-20H03454, KAKENHI-PROJECT-19K16527
[Journal Article] Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells2021
- Author(s)
  Yanagi Kouichi、Komatsu Toru、Ogihara Shusuke、Okabe Takayoshi、Kojima Hirotatsu、Nagano Tetsuo、Ueno Tasuku、Hanaoka Kenjiro、Urano Yasuteru
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 1 Pages: 109311-109311
- DOI
  10.1016/j.celrep.2021.109311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04694, KAKENHI-PUBLICLY-20H04767, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H02846
[Journal Article] Discovery of an F-actin-binding small molecule serving as a fluorescent probe and a scaffold for functional probes2021
- Author(s)
  Takagi T, Ueno T, Ikawa K, Asanuma D, Nomura Y, Uno S, Komatsu T, Kamiya M, Hanaoka K, Okimura C, Iwadate Y, Hirose K, Nagano T, Sugimura K and Urano Y.
- Journal Title
  
  Science Advances
  
  Volume: 7(47) Issue: 47
- DOI
  10.1126/sciadv.abg8585
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02896, KAKENHI-PROJECT-17K07366, KAKENHI-PROJECT-19K16139, KAKENHI-PROJECT-20H03227, KAKENHI-PUBLICLY-20H04694, KAKENHI-PLANNED-21H05262, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-20H02701, KAKENHI-PROJECT-21K19228
[Journal Article] Antibody Clicking as a Strategy to Modify Antibody Functionalities on the Surface of Targeted Cells2020
- Author(s)
  Komatsu Toru、Kyo Etsu、Ishii Haruki、Tsuchikama Kyoji、Yamaguchi Aiko、Ueno Tasuku、Hanaoka Kenjiro、Urano Yasuteru
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Issue: 37 Pages: 15644-15648
- DOI
  10.1021/jacs.0c05331
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04694, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-19H02846
[Journal Article] A cytosolically localized far-red to near-infrared rhodamine-based fluorescent probe for calcium ions2020
- Author(s)
  Numasawa Koji、Hanaoka Kenjiro、Ikeno Takayuki、Echizen Honami、Ishikawa Tomoe、Morimoto Masakazu、Komatsu Toru、Ueno Tasuku、Ikegaya Yuji、Nagano Tetsuo、Urano Yasuteru
- Journal Title
  
  The Analyst
  
  Volume: 145 Issue: 23 Pages: 7736-7740
- DOI
  10.1039/d0an01739f
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H05414, KAKENHI-PUBLICLY-20H04694, KAKENHI-PUBLICLY-20H04767, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-20H02701, KAKENHI-PROJECT-18J23221
[Journal Article] Covalent Self-labeling of Tagged Proteins with Chemical Fluorescent Dyes in BY-2 Cells and Arabidopsis Seedlings2020
- Author(s)
  Iwatate, J.R., Yoshinari, A., Yagi, N., Grzybowski, M., Ogasawara, H., Kamiya, M., Komatsu, T., Taki, M., Yamaguchi, S., Frommer, W.B. and Nakamura, M.
- Journal Title
  
  The Plant Cell
  
  Volume: 32 Issue: 10 Pages: 3081-3094
- DOI
  10.1105/tpc.20.00439
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0195, KAKENHI-PUBLICLY-20H04694, KAKENHI-PROJECT-19H02846, KAKENHI-PUBLICLY-19H04858
[Journal Article] Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples2020
- Author(s)
  Shingo Sakamoto, Toru Komatsu, Rikiya Watanabe, Yi Zhang, Taiki Inoue, Mitsuyasu Kawaguchi, Hidehiko Nakagawa, Takaaki Ueno, Takuji Okusaka, Kazufumi Honda, Hiroyuki Noji, Yasuteru Urano
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 11
- DOI
  10.1126/sciadv.aay0888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14260, KAKENHI-PUBLICLY-18H04538, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-18J23224, KAKENHI-PROJECT-17K19477, KAKENHI-PROJECT-18K14358, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H03856, KAKENHI-PROJECT-19H05624
[Journal Article] Development and validation of an improved diced electrophoresis gel assay cutter-plate system for enzymomics studies2019
- Author(s)
  Komatsu Toru、Shimoda Masahiro、Kawamura Yukiko、Urano Yasuteru、Nagano Tetsuo
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  
  Volume: 1867 Issue: 1 Pages: 82-87
- DOI
  10.1016/j.bbapap.2018.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PUBLICLY-18H04538
[Journal Article] Metabolic-Pathway-Oriented Screening Targeting S-Adenosyl-l-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols2019
- Author(s)
  Ogihara Shusuke、Komatsu Toru、Itoh Yukihiro、Miyake Yuka、Suzuki Takayoshi、Yanagi Kouichi、Kimura Yusuke、Ueno Tasuku、Hanaoka Kenjiro、Kojima Hirotatsu、Okabe Takayoshi、Nagano Tetsuo、Urano Yasuteru
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 142 Issue: 1 Pages: 21-26
- DOI
  10.1021/jacs.9b08698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-17K19477
[Journal Article] Separation-Based Enzymomics Assay for the Discovery of Altered Peptide-Metabolizing Enzymatic Activities in Biosamples2019
- Author(s)
  Ichihashi Yuki、Komatsu Toru、Kyo Etsu、Matsuzaki Hiroyuki、Hata Keisuke、Watanabe Toshiaki、Ueno Tasuku、Hanaoka Kenjiro、Urano Yasuteru
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 18 Pages: 11497-11501
- DOI
  10.1021/acs.analchem.9b03016
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-17K19477, KAKENHI-PROJECT-16H05099
[Journal Article] Development of ratiometric carbohydrate sensor based on boron dipyrromethene (BODIPY) scaffold2019
- Author(s)
  Cheruthu Nusaiba Madappuram、Komatsu Toru、Ueno Tasuku、Hanaoka Kenjiro、Urano Yasuteru
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Issue: 22 Pages: 126684-126684
- DOI
  10.1016/j.bmcl.2019.126684
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-19H05632, KAKENHI-PROJECT-19H02846, KAKENHI-PROJECT-17K19477, KAKENHI-PROJECT-16H05099
[Journal Article] High-throughput single-molecule bioassay using micro-reactor arrays with a concentration gradient of target molecules2018
- Author(s)
  Watanabe Rikiya、Komatsu Toru、Sakamoto Shingo、Urano Yasuteru、Noji Hiroyuki
- Journal Title
  
  Lab on a Chip
  
  Volume: 18 Issue: 18 Pages: 2849-2853
- DOI
  10.1039/c8lc00535d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PUBLICLY-17H05871, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04667, KAKENHI-PROJECT-17H03660
[Journal Article] Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe2018
- Author(s)
  Kubo Hidemasa、Hanaoka Kenjiro、Kuriki Yugo、Komatsu Toru、Ueno Tasuku、Kojima Ryosuke、Kamiya Mako、Murayama Yasutoshi、Otsuji Eigo、Urano Yasuteru
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 17781-6942
- DOI
  10.1038/s41598-018-36062-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PLANNED-15H05951, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H02606, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-16J09996
[Journal Article] Synthesis of unsymmetrical Si-rhodamine fluorophores and application to a far-red to near-infrared fluorescence probe for hypoxia2018
- Author(s)
  Hanaoka Kenjiro、Kagami Yu、Piao Wen、Myochin Takuya、Numasawa Koji、Kuriki Yugo、Ikeno Takayuki、Ueno Tasuku、Komatsu Toru、Terai Takuya、Nagano Tetsuo、Urano Yasuteru
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 50 Pages: 6939-6942
- DOI
  10.1039/c8cc02451k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PUBLICLY-18H04535, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-16J01710, KAKENHI-PROJECT-16J09996, KAKENHI-PROJECT-18J23221, KAKENHI-PROJECT-18H02103
[Journal Article] Red-Shifted Fluorogenic Substrate for Detection of lacZ-Positive Cells in Living Tissue with Single-Cell Resolution2018
- Author(s)
  Ito Hiroki、Kawamata Yu、Kamiya Mako、Tsuda-Sakurai Kayoko、Tanaka Shinji、Ueno Tasuku、Komatsu Toru、Hanaoka Kenjiro、Okabe Shigeo、Miura Masayuki、Urano Yasuteru
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 48 Pages: 15702-15706
- DOI
  10.1002/anie.201808670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PLANNED-15H05951, KAKENHI-PUBLICLY-18H04538, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-18H04727, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H02606, KAKENHI-PROJECT-17H01387, KAKENHI-PROJECT-16H05099
[Journal Article] Establishment of Molecular Design Strategy To Obtain Activatable Fluorescent Probes for Carboxypeptidases2018
- Author(s)
  Kuriki Yugo、Kamiya Mako、Kubo Hidemasa、Komatsu Toru、Ueno Tasuku、Tachibana Ryo、Hayashi Kento、Hanaoka Kenjiro、Yamashita Suguru、Ishizawa Takeaki、Kokudo Norihiro、Urano Yasuteru
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 5 Pages: 1767-1773
- DOI
  10.1021/jacs.7b11014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PLANNED-15H05951, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H02606, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-16J09996, KAKENHI-PROJECT-17J10083, KAKENHI-PROJECT-17H04279
[Journal Article] An Activatable Photosensitizer Targeted to γ-Glutamyltranspeptidase2017
- Author(s)
  Chiba Mayumi、Ichikawa Yuki、Kamiya Mako、Komatsu Toru、Ueno Tasuku、Hanaoka Kenjiro、Nagano Tetsuo、Lange Norbert、Urano Yasuteru
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 56 Issue: 35 Pages: 10418-10422
- DOI
  10.1002/anie.201704793
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PLANNED-15H05951, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H02606, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371
[Journal Article] Development of an Azoreductase-based Reporter System with Synthetic Fluorogenic Substrates2017
- Author(s)
  Narae Shin, Kenjiro Hanaoka, Wen Piao, Takuya Miyakawa, Tomotsumi Fujisawa, Satoshi Takeuchi, Shodai Takahashi, Toru Komatsu, Tasuku Ueno, Takuya Terai, Tahei Tahara, Masaru Tanokura, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 12 Issue: 2 Pages: 558-563
- DOI
  10.1021/acschembio.6b00852
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00823, KAKENHI-PLANNED-25104005, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H04102, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-16K17859, KAKENHI-PROJECT-17K05756
[Journal Article] Fluorescence detection of serum albumin with a turnover-based sensor utilizing Kemp elimination reaction2017
- Author(s)
  Sakamoto Shingo、Komatsu Toru、Ueno Tasuku、Hanaoka Kenjiro、Urano Yasuteru
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 15 Pages: 3464-3467
- DOI
  10.1016/j.bmcl.2017.05.076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371
[Journal Article] Development of a Reversible Fluorescent Probe for Reactive Sulfur Species, Sulfane Sulfur, and its Biological Application2017
- Author(s)
  Takano Y, Hanaoka K, Shimamoto K, Miyamoto R, Komatsu T, Ueno T, Terai T, Kimura H, Nagano T, Urano Y
- Journal Title
  
  Chem Commun
  
  Volume: 53 Issue: 6 Pages: 1064-1067
- DOI
  10.1039/c6cc08372b
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-17K08331, KAKENHI-PROJECT-17K08613, KAKENHI-PROJECT-26460115, KAKENHI-PROJECT-26460352
[Journal Article] Discovery of Cell-type-specific and Disease-related Enzymatic Activity Changes via Global Evaluation of Peptide Metabolism2017
- Author(s)
  Jun Onagi, Toru Komatsu, Yuki Ichihashi, Yugo Kuriki, Mako Kamiya, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Hiroyuki Matsuzaki, Keisuke Hata, Toshiaki Watanabe, Tetsuo Nagano, and Yasuteru Urano
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 139 Issue: 9 Pages: 3465-3472
- DOI
  10.1021/jacs.6b11376
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15K05529
[Journal Article] Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy2017
- Author(s)
  Piao Wen、Hanaoka Kenjiro、Fujisawa Tomotsumi、Takeuchi Satoshi、Komatsu Toru、Ueno Tasuku、Terai Takuya、Tahara Tahei、Nagano Tetsuo、Urano Yasuteru
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 139 Issue: 39 Pages: 13713-13719
- DOI
  10.1021/jacs.7b05019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05756, KAKENHI-PROJECT-17K19477, KAKENHI-PUBLICLY-16H00823, KAKENHI-PLANNED-25104005, KAKENHI-PROJECT-16H04102, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-16J01710, KAKENHI-PROJECT-15K05529, KAKENHI-PROJECT-16K17859
[Journal Article] Potential of Enzymomics Methodologies to Characterize Disease-Related Protein Functions2017
- Author(s)
  Toru Komatsu
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 65 Issue: 7 Pages: 605-610
- DOI
  10.1248/cpb.c17-00144
- NAID
  130006772511
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19477, KAKENHI-PROJECT-15H05371
[Journal Article] Enzyme-Loaded Polyion Complex Vesicles as in Vivo Nanoreactors Working Sustainably under the Blood Circulation: Characterization and Functional Evaluation2017
- Author(s)
  Daiki Sueyoshi, Yasutaka Anraku, Toru Komatsu, Yasuteru Urano and Kazunori Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 18 Issue: 4 Pages: 1189-1196
- DOI
  10.1021/acs.biomac.6b01870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15K12536, KAKENHI-PROJECT-14J10621
[Journal Article] Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide2017
- Author(s)
  K. Hanaoka, K. Sasakura, Y. Suwanai, S. Toma-Fukai, K. Shimamoto, Y. Takano, N. Shibuya, T. Terai, T. Komatsu, T. Ueno, Y. Ogasawara, Y. Tsuchiya, Y. Watanabe, H. Kimura, C. Wang, M. Uchiyama, H. Kojima, T. Okabe, Y. Urano, T. Shimizu, T. Nagano
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 40227-40227
- DOI
  10.1038/srep40227
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00823, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-14F04908, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15K18994, KAKENHI-PROJECT-26460352, KAKENHI-PROJECT-16K15123, KAKENHI-PROJECT-17K08331, KAKENHI-PROJECT-17K08613, KAKENHI-PROJECT-17H06173, KAKENHI-PROJECT-26460115
[Journal Article] Meeting Proceedings ICBS2016-Translating the Power of Chemical Biology to Clinical Advances2017
- Author(s)
  Yugo Kuriki, Toru Komatsu, Peter D. Ycas, Sara K. Coulup, Erick J. Carlson, and William C. K. Pomerantz
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 12 Issue: 4 Pages: 869-877
- DOI
  10.1021/acschembio.7b00205
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Development of Chemical Tools to Monitor and Control Isoaspartyl Peptide Methyltransferase Activity2017
- Author(s)
  Yusuke Kimura, Toru Komatsu, Kouichi Yanagi, Kenjiro Hanaoka, Tasuku Ueno, Takuya Terai, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 56 Issue: 1 Pages: 153-157
- DOI
  10.1002/anie.201608677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Detection of NAD(P)H-dependent enzyme activity by time-domain ratiometry of terbium luminescence2016
- Author(s)
  Takuya Terai, Hiroki Ito, Kenjiro Hanaoka, Toru Komatsu, Tasuku Ueno, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 26 Issue: 9 Pages: 2314-2317
- DOI
  10.1016/j.bmcl.2016.03.038
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05529, KAKENHI-PUBLICLY-26104509, KAKENHI-PROJECT-24689003, KAKENHI-PUBLICLY-16H00823, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Identification of Lung Inflammation-Related Elevation of Acylamino Acid Releasing Enzyme (APEH) Activity Using an Enzymomics Approach2016
- Author(s)
  Yoko Takano, Kenjiro Hanaoka, Kazuhito Shimamoto, Ryo Miyamoto, Toru Komatsu, Tasuku Ueno, Takuya Terai, Hideo Kimura, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 11 Pages: 1533-1538
- DOI
  10.1248/cpb.c16-00540
- NAID
  130005268073
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00823, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] ICBS and ECBS Chemical Biology Meeting 2015 - Let Them Come to Berlin2016
- Author(s)
  Toru Komatsu and Satpal Virdee
- Journal Title
  
  ACS Chem. Biol.,
  
  Volume: 11 Issue: 5 Pages: 1159-1166
- DOI
  10.1021/acschembio.6b00268
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Rapid and sensitive detection of early esophageal squamous cell carcinoma with fluorescence probe targeting dipeptidylpeptidase IV.2016
- Author(s)
  Onoyama H, Kamiya M, Kuriki Y, Komatsu T, Abe H, Tsuji Y, Yagi K, Yamagata Y, Aikou S, Nishida M, Mori K, Yamashita H, Fujishiro M, Nomura S, Shimizu N, Fukayama M, Koike K, Urano Y, Seto Y
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 26399-26399
- DOI
  10.1038/srep26399
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05951, KAKENHI-PROJECT-16H02606, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-16J09996, KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-15H04806
[Journal Article] Toward Total Synthesis of Cell Function: Reconstituting Cell Dynamics with Synthetic Biology2016
- Author(s)
  Allen K. Kim, Robert DeRose, Tasuku Ueno, Benjamin Lin, Toru Komatsu, Hideki Nakamura, and Takanari Inoue
- Journal Title
  
  Sci. Signaling
  
  Volume: 9 Issue: 414
- DOI
  10.1126/scisignal.aac4779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15H05371
[Journal Article] Protein-Coupled Fluorescent Probe To Visualize Potassium Ion Transition on Cellular Membranes2016
- Author(s)
  Tomoya Hirata, Takuya Terai, Hisao Yamamura, Manabu Shimonishi, Toru Komatsu, Kenjiro Hanaoka, Tasuku Ueno, Yuji Imaizumi, Tetsuo Nagano, and Yasuteru Urano
- Journal Title
  
  Analytical Chemistry
  
  Volume: 88 Issue: 5 Pages: 2693-2700
- DOI
  10.1021/acs.analchem.5b03970
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05529, KAKENHI-PUBLICLY-15H01408, KAKENHI-PUBLICLY-26104509, KAKENHI-PROJECT-25460104, KAKENHI-PROJECT-26670039, KAKENHI-PROJECT-26293021, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Discovery of Pyruvylated Peptide-metabolizing Enzyme Using a Fluorescent Substrate-based Protein Discovery Technique2016
- Author(s)
  Kentaro Yoshioka, Toru Komatsu, Kenjiro Hanaoka, Tasuku Ueno, Takuya Terai, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Chemical Communications
  
  Volume: 52 Issue: 23 Pages: 4377-4380
- DOI
  10.1039/c6cc00829a
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26104509, KAKENHI-PROJECT-24689003, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Development of Practical Red Fluorescent Probe for Cytoplasmic Calcium Ions with Greatly Improved Cell-membrane Permeability2016
- Author(s)
  Kazuhisa Hirabayashi, Kenjiro Hanaoka, Takahiro Egawa, Chiaki Kobayashi, Shodai Takahashi, Toru Komatsua, Tasuku Ueno, Takuya Terai, Yuji Ikegaya, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Cell Calcium
  
  Volume: 60 Issue: 4 Pages: 256-265
- DOI
  10.1016/j.ceca.2016.06.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H00823, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Unexpected photo-instability of 2,6-sulfonamide-substituted BODIPYs and its application to development of caged GABA2016
- Author(s)
  Aoi Takeda, Toru Komatsu, Hiroshi Nomura, Naka Masamitsu, Norio Matsuki, Yuji Ikegaya, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  ChemBioChem
  
  Volume: 17 Issue: 13 Pages: 1-9
- DOI
  10.1002/cbic.201600097
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H00823, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-15K14937
[Journal Article] Development of a Sensitive Bioluminogenic Probe for Imaging Highly Reactive Oxygen Species in Living Rats2015
- Author(s)
  Ryosuke Kojima, Hideo Takakura, Mako Kamiya, Eiji Kobayashi, Toru Komatsu, Tasuku Ueno, Takuya Terai, Kenjiro Hanaoka, Tetsuo Nagano, and Yasuteru Urano
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 54 Issue: 49 Pages: 14768-14771
- DOI
  10.1002/ange.201507530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14937, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371
[Journal Article] Gliotoxin Suppresses NF-kappaB Activation by Selectively Inhibiting Linear Ubiquitin Chain Assembly Complex (LUBAC)2015
- Author(s)
  Hiroki Sakamoto, Shinichiro Egashira, Nae Saito, Takayoshi Kirisako, Simon Miller, Yoshiteru Sasaki, Tadahiko Matsumoto, Manabu Shimonishi, Toru Komatsu, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Hirotatsu Kojima, Takayoshi Okabe, Soichi Wakatsuki, Kazuhiro Iwai, Tetsuo Nagano
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 10 Issue: 3 Pages: 675-681
- DOI
  10.1021/cb500653y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J11914, KAKENHI-PROJECT-22000006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PUBLICLY-26104509, KAKENHI-PROJECT-26460573, KAKENHI-PROJECT-26670154, KAKENHI-PROJECT-25253019, KAKENHI-PROJECT-15H05371
[Journal Article] Detection of NAD (P) H-dependent enzyme activity with dynamic luminescence quenching of terbium complexes2015
- Author(s)
  Hiroki Ito, Takuya Terai, Kenjiro Hanaoka, Tasuku Ueno, Toru Komatsu, Tetsuo Nagano and Yasuteru Urano
- Journal Title
  
  Chem. Commun.
  
  Volume: 51 Issue: 39 Pages: 8319-8322
- DOI
  10.1039/c5cc01613d
- Description
  in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-15K14937, KAKENHI-PUBLICLY-26104509, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-24689003
[Journal Article] Identification of tissue-restricted bio-reaction suitable for in vivo targeting by fluorescent substrate library-based enzyme discovery2015
- Author(s)
  Kentaro Yoshioka, Toru Komatsu, Akihiro Nakada, Jun Onagi, Yugo Kuriki, Mitsuyasu Kawaguchi, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Tetsuo Nagano, and Yasuteru Urano
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 137 Issue: 38 Pages: 12187-12190
- DOI
  10.1021/jacs.5b05884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15K18899, KAKENHI-PUBLICLY-26104509, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-24689003
[Journal Article] Evaluation of Enzymatic Activities in Living Systems with Small-molecular Fluorescent Substrate Probes2015
- Author(s)
  Toru Komatsu and Yasuteru Urano
- Journal Title
  
  Anal. Sci.
  
  Volume: 31 Issue: 4 Pages: 257-265
- DOI
  10.2116/analsci.31.257
- NAID
  130005061526
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14937, KAKENHI-PROJECT-15H05371
[Journal Article] New Class of Bioluminogenic Probe Based on Bioluminescent Enzyme-Induced Electron Transfer: BioLeT.2015
- Author(s)
  Takakura H, Kojima R, Kamiya M, Kobayashi E, Komatsu T, Ueno T, Terai T, Hanaoka K, Nagano T, Urano Y.
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 137 Issue: 12 Pages: 4010-4013
- DOI
  10.1021/ja511014w
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25113707, KAKENHI-PUBLICLY-26104509, KAKENHI-PROJECT-15K14937, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371
[Journal Article] Analysis of Chemical Equilibrium of Silicon-Substituted Fluorescein and Its Application to Develop a Scaffold for Red Fluorescent Probes2015
- Author(s)
  K. Hirabayashi, K. Hanaoka, T. Takayanagi, Y. Toki, T. Egawa, M. Kamiya, T. Komatsu, T. Ueno, T. Terai, K. Yoshida, M. Uchiyama, T. Nagano, and Y. Urano
- Journal Title
  
  Analytical Chemistry
  
  Volume: 87(17) Issue: 17 Pages: 9061-9069
- DOI
  10.1021/acs.analchem.5b02331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26410154, KAKENHI-PLANNED-15H05951, KAKENHI-PUBLICLY-26104509, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-24689003
[Journal Article] Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport2015
- Author(s)
  Takuya Terai, Moe Kohno, Gaelle Boncompain, Shigeru Sugiyama, Nae Saito, Ryo Fujikake, Tasuku Ueno, Toru Komatsu, Kenjiro Hanaoka, Takayoshi Okabe, Yasuteru Urano, Franck Perez, and Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 137 Issue: 33 Pages: 10464-10467
- DOI
  10.1021/jacs.5b05672
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14937, KAKENHI-PUBLICLY-26104509, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371, KAKENHI-PROJECT-25286051
[Journal Article] Development of a Series of Near-Infrared Dark Quenchers Based on Si-rhodamines and Their Application to Fluorescent Probes2015
- Author(s)
  Takuya Myochin, Kenjiro Hanaoka, Shimpei Iwaki, Tasuku Ueno, Toru Komatsu, Takuya Terai, Tetsuo Nagano, and Yasuteru Urano
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: １３７ Issue: 14 Pages: 4759-4765
- DOI
  10.1021/jacs.5b00246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J11590, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24659042, KAKENHI-PROJECT-24689003, KAKENHI-PUBLICLY-26104509, KAKENHI-PROJECT-15K14937, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H05371
[Journal Article] Design Strategy for Small Molecule-based Targeted MRI Contrast Agents : Application for Detection of Atherosclerotic Plaques2014
- Author(s)
  Shimpei Iwaki, Kazuya Hokamura, Mikako Ogawa, Yasuo Takehara, Yasuaki Muramatsu, Takehiro Yamane, Kazuhisa Hirabayashi, Yuji Morimoto, Kohsuke Hagisawa, Kazuhide Nakahara, Tomoko Mineno, Takuya Terai, Toru Komatsu, Tasuku Ueno, Keita Tamura, Yusuke Adachi, Yasunobu Hirata, Makoto Arita, Hiroyuki Arai, Kazuo Umemura, Tetsuo Nagano and Kenjiro Hanaoka
- Journal Title
  
  Org. Biomol. Chem
  
  Volume: 12 Pages: 8611-8618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Boron Dipyrromethene as a Fluorescent Caging Group for Single-photon Uncaging with Long-wavelength Visible Light2014
- Author(s)
  Nobuhiro Umeda, Hironori Takahashi, Mako Kamiya, Tasuku Ueno, Toru Komatsu, Takuya Terai, Kenjiro Hanaoka, Tetsuo Nagano, and Yasuteru Urano
- Journal Title
  
  ACS Chem. Biol
  
  Volume: 9 Issue: 10 Pages: 2242-2246
- DOI
  10.1021/cb500525p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PUBLICLY-25104506, KAKENHI-PROJECT-25870180, KAKENHI-PUBLICLY-26104509, KAKENHI-PLANNED-26111012
[Journal Article] Fluorometric Assay of Integrin Activity with a Small-molecular Probe that Senses the Binding Site Microenvironment2014
- Author(s)
  Toru Komatsu, Aoi Takeda, Kenjiro Hanaoka, Takuya Terai, Tasuku Ueno, Yukio Tada, Tetsuo Nagano and Yasuteru Urano
- Journal Title
  
  Chem. Commun
  
  Volume: 50 Issue: 100 Pages: 15894-15896
- DOI
  10.1039/c4cc05591h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PUBLICLY-26104509
[Journal Article] Selective Ablation of β-Galactosidase-expressing Cells with a Rationally Designed Activatable Photosensitizer2014
- Author(s)
  Yuki Ichikawa, Mako Kamiya, Fumiaki Obata, Masayuki Miura, Takuya Terai, Toru Komatsu, Tasuku Ueno, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 53 Issue: 26 Pages: 6772-6775
- DOI
  10.1002/anie.201403221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-23229002, KAKENHI-PUBLICLY-25104506, KAKENHI-PUBLICLY-25113707, KAKENHI-PUBLICLY-26104509, KAKENHI-PLANNED-26111012
[Journal Article] Thermal or Mechanical Stimuli-induced Photoluminescence Color Change of Molecular Assembly Composed of An Amphiphilic Anthracene Derivative in Water2014
- Author(s)
  Yoshimitsu Sagara, Toru Komatsu, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Takashi Kato, and Tetsuo Nagano
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 20 Issue: 33 Pages: 10397-10403
- DOI
  10.1002/chem.201403025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PUBLICLY-26104509
[Journal Article] Rapidly Rendering Cells Phagocytic Through a Cell-surface Display Technique and Concurrent Rac Activation2014
- Author(s)
  Hiroki Onuma, Toru Komatsu, Makoto Arita, Kenjiro Hanaoka, Tasuku Ueno, Takuya Terai, Tetsuo Nagano and Takanari Inoue
- Journal Title
  
  Sci. Signaling
  
  Volume: 7 Issue: 334
- DOI
  10.1126/scisignal.2005123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PUBLICLY-26104509
[Journal Article] Diced electrophoresis gel assay for screening enzymes with specified activities2013
- Author(s)
  Toru Komatsu, Kenjiro Hanaoka, Alexander Adibekian, Takuya Terai, Tasuku Ueno, Mitsuyasu Kawaguchi, Benjamin Cravatt and Tetsuo Nagano
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 135 Pages: 6002-6005
- NAID
  130005103925
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] TokyoGreen derivatives as specific and practical fluorescent probes for UDP-glucuronosyltransferase (UGT) 1A12013
- Author(s)
  Takuya Terai, Rie Tomiyasu, Tomoe Ota, Tasuku Ueno, Toru Komatsu, Kenjiro Hanaoka, Yasuteru Urano, Tetuo Nagano
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Pages: 3101-3103
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] A Water-soluble Mechanochromic Luminescent Pyrene Derivative Exhibiting Recovery of the Initial Photoluminescence Color in a High-humidity Environment2013
- Author(s)
  相良剛光
- Journal Title
  
  Advanced Functional Materials]
  
  Volume: 23(in press) Issue: 42 Pages: 5277-5284
- DOI
  10.1002/adfm.201300180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07267, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24655147
[Journal Article] Development of a new class of azo-based fluorescence probes to detect different levels of hypoxia2013
- Author(s)
  Wen Piao, Satoru Tsuda, Yuji Tanaka, Satoshi Maeda, Fengyi Liu, Shodai Takahashi, Yu Kushida, Toru Komatsu, Tasuku Ueno, Takuya Terai, Toru Nakazawa, Masanobu Uchiyama, Keiji Morokuma, Tetsuo Nagano, and Kenjiro Hanaoka
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Pages: 13028-13032
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Impact of Preferential Indium Nucleation on Electrical Conductivity of VLS Grown Indium-Tin-Oixde Nanowires2013
- Author(s)
  G. Meng
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 135 Issue: 18 Pages: 7033-7038
- DOI
  10.1021/ja401926u
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651138, KAKENHI-PROJECT-24655147
[Journal Article]2013
- Author(s)
  Takahiro Egawa, Kazuhisa Hirabayashi, Yuichiro Koide, Chiaki Kobayashi, Naoya Takahashi, Tomoko Mineno, Takuya Terai, Tasuku Ueno, Toru Komatsu, Yuji Ikegaya, Norio Matsuki, Tetsuo Nagano and Kenjiro Hanaoka
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Pages: 38740-3877
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Development of Azo-based Fluorescence Probes to Detect Different Levels of Hypoxia2013
- Author(s)
  Wen Piao, Satoru Tsuda, Yuji Tanaka, Satoshi Maeda, Fengyi Liu, Shodai Takahashi, Yu Kushida, Toru Komatsu, Tasuku Ueno Takuya Terai, Toru Nakazawa, Masanobu Uchiyama, Keiji Morokuma, Tetsuo Nagano, KenjiroHanaoka
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Issue: 49 Pages: 13028-13032
- DOI
  10.1002/anie.201305784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10749, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-23685004, KAKENHI-PROJECT-24655147, KAKENHI-PROJECT-24659042, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24689003, KAKENHI-PROJECT-24700472
[Journal Article] Covalent attachment of mechanoresponsive luminescent micelles to glasses and polymers in aqueous conditions2013
- Author(s)
  Yoshimitsu Sagara, Toru Komatsu, Tasuku Ueno, Kenjiro Hanaoka, Takashi Kato, and Tetsuo Nagano
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 136 Pages: 4273-4280
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] TokyoGreen Derivatives as Specific and Practical Fluorescent Probes for UDP-Glucuronosyltransferase (UGT) 1A12013
- Author(s)
  Takuya Terai, Rie Tomiyasu, Tomoe Ota, Tasuku Ueno, Toru Komatsu, Kenjiro Hanaoka, Yasuteru Urano and Tetsuo Nagano
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Issue: 30 Pages: 3101-3103
- DOI
  10.1039/c3cc38810g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-23651231, KAKENHI-PROJECT-24655147, KAKENHI-PLANNED-20117003
[Journal Article] Red Fluorescence Probe for Monitoring Dynamics of Cytoplasmic Calcium Ion2013
- Author(s)
  Takahiro Egawa, Kazuhisa Hirabayashi, Yuichiro Koide, Chiaki Kobayashi, Naoya Takahashi, Tomoko Mineno, Takuya Terai, Tasuku Ueno, Toru Komatsu, Yuji Ikegaya, Norio Matsuki, Tetsuo Nagano, and Kenjiro Hanaoka
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Issue: 14 Pages: 3874-3877
- DOI
  10.1002/anie.201210279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J01172, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24655147
[Journal Article] Diced electrophoresis gel assay for screening enzymes with specified activities2013
- Author(s)
  Toru Komatsu, . .. Mitsuyasu Kawaguchi (7^<th> author))
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 135 Issue: 16 Pages: 6002-6005
- DOI
  10.1021/ja401792d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10869, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24655147
[Journal Article] Covalent Attachment of Mechanoresponsive Luminescent Micelles to Glasses and Polymers in Aqueous Conditions2013
- Author(s)
  Yoshimitsu Sagara, Toru Komatsu, Tasuku Ueno, Kenjiro Hanaoka, Takashi Kato, and Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 11 Pages: 4273-4280
- DOI
  10.1021/ja412670g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24655147
[Journal Article] A water-soluble mechanochromic luminescent pyrene derivative exhibiting recovery of the initial photoluminescence color in a high-humidity environment2013
- Author(s)
  Yoshimitsu Sagara, Toru Komatsu, Tasuku Ueno, Kenjiro Hanaoka, Takashi Kato and Tetsuo Nagano
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 23 Pages: 5277-5284
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Design Strategy for a Near-infrared (NIR) Fluorescence Probe for Matrix Metalloproteinase Utilizing Highly Cell-permeable Boron Dipyrromethene (BODIPY)2012
- Author(s)
  Takuya Myochin, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai and Tetsuo Nagano
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 134 Issue: 33 Pages: 13730-13737
- DOI
  10.1021/ja303931b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24655147, KAKENHI-PROJECT-24659042
[Journal Article] Design strategy for a near-infrared (NIR) fluorescence probe for matrix metalloproteinase utilizing highly cell-permeable boron dipyrromethene (BODIPY)2012
- Author(s)
  Takuya Myochin, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai, and Tetsuo Nagano
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 134 Pages: 13730-13737
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] A Reversible Near-Infrared Fluorescence Probe for Reactive Oxygen Species Based on Te-rhodamine2012
- Author(s)
  Yuichiro Koide, Mitsuyasu Kawaguchi, Yasuteru Urano, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai, Tetsuo Nagano
- Journal Title
  
  Chemical Communications
  
  Volume: 48 Issue: 25 Pages: 3091-3093
- DOI
  10.1039/c2cc18011a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10632, KAKENHI-PROJECT-22000006
[Journal Article] Near-infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold2012
- Author(s)
  Daihi Oushiki, Hirotatsu Kojima, Yuki Takahashi, Toru Komatsu, Takuya Terai, Kenjiro Hanaoka, Makiya Nishikawa, Yoshinobu Takakura and Tetsuo Nagano
- Journal Title
  
  Anal. Chem.
  
  Volume: 84 Issue: 10 Pages: 4404-4410
- DOI
  10.1021/ac300061a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-23651231
[Journal Article] Red Fluorescent Scaffold for Highly Sensitive Protease Activity Probes2012
- Author(s)
  Yu Kushida, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai, Tasuku Ueno, Kengo Yoshida, Masanobu Uchiyama, Tetsuo Nagano
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Issue: 12 Pages: 3908-3911
- DOI
  10.1016/j.bmcl.2012.04.114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24659042
[Journal Article] Development of hypoxia-sensitive Gd^<3+>-based MRI contrast agents2012
- Author(s)
  Shimpei Iwaki, Kenjiro Hanaoka, Wen Piao, Toru Komatsu, Tasuku Ueno, Takuya Terai, Tetsuo Nagano
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 22 Issue: 8 Pages: 2798-2802
- DOI
  10.1016/j.bmcl.2012.02.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Reversible Off-On Fluorescence Probe for Hypoxia and Imaging of Hypoxia-Normoxia Cycles in Live Cells2012
- Author(s)
  Shodai Takahashi, Wen Piao, Yuriko Matsumura, Toru Komatsu, Tasuku Ueno, Takuya Terai, Toshiaki Kamachi, Masahiro Kohno, Tetsuo Nagano and Kenjiro Hanaoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 134 Issue: 48 Pages: 19588-19591
- DOI
  10.1021/ja310049d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24655147, KAKENHI-PROJECT-24659042, KAKENHI-PROJECT-24689003
[Journal Article] Highly activatable and environment- insensitive optical highlighters for selective spatiotemporal imaging of target proteins2012
- Author(s)
  Tomonori Kobayashi, Toru Komatsu, Mako Kamiya, Cláudia Campos, Marcos González-Gaitán, Takuya Terai, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 134 Pages: 11153-11160
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Reversible off-on fluorescence probe for hypoxia and imaging of hypoxia-normoxia cycles in live cells2012
- Author(s)
  Shodai Takahashi, Wen Piao, Yuriko Matumura, Toru Komatsu, Tasuku Ueno, Takuya Terai, Toshiaki Kamachi, Masahiro Kohno, Tetsuo Nagano, Kenjiro Hanaoka
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 134 Pages: 19588-19591
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Red fluorescent scaffold for highly sensitive protease activity probes2012
- Author(s)
  Yu Kushida, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai, Tasuku Ueno, Kengo Yoshida, Masanobu Uchiyama, Tetsuo Nagano
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 22 Pages: 3908-3911
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Development of a highly selective fluorescence probe for hydrogen sulfide2011
- Author(s)
  Sasakura K, Hanaoka K, Shibuya N, Mikami Y, Kimura Y, Komatsu T, Ueno T, Terai T, Kimura H, Nagano T
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 133(45) Issue: 45 Pages: 18003-18005
- DOI
  10.1021/ja207851s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J10626, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-22590258, KAKENHI-PROJECT-23659089, KAKENHI-PROJECT-23790316
[Journal Article] Development of a Potassium Ion-Selective Fluorescent Sensor Based on 3-Styrylated BODIPY2011
- Author(s)
  Tomoya Hirata, Takuya Terai, Toru Komatsu, Kenjiro Hanaoka, Tetsuo Nagano
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Issue: 20 Pages: 6090-6093
- DOI
  10.1016/j.bmcl.2011.08.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Selective Two-Step Labeling of Proteins with an Off-On Fluorescence Probe2011
- Author(s)
  Kazuhisa Hirabayashi, Kenjiro Hanaoka, Manabu Shimonishi, Takuya Terai, Toru Komatsu, Tasuku Ueno, Tetsuo Nagano
- Journal Title
  
  Chemistry-A European Journal
  
  Volume: 17 Issue: 52 Pages: 14763-14771
- DOI
  10.1002/chem.201102664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Development of a Fluorescein Analogue, TokyoMagenta, as a Novel Scaffold for Fluorescence Probes in Red Region2011
- Author(s)
  Takahiro Egawa, Yuichiro Koide, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai, Tetsuo Nagano
- Journal Title
  
  Chemical Communications
  
  Volume: 47 Pages: 4162-4164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Development of a Far-Red to Near-Infrared Fluorescence Probe for Calcium Ion and its Application to Multicolor Neuronal Imaging2011
- Author(s)
  Takahiro Egawa, Kenjiro Hanaoka, Yuichiro Koide, Sakiko Ujita, Naoya Takahashi, Yuji Ikegaya, Norio Matsuki, Takuya Terai, Tasuku Ueno, Toru Komatsu, Tetsuo Nagano
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 133 Issue: 36 Pages: 14157-14159
- DOI
  10.1021/ja205809h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Development of a Highly Selective Fluorescence Probe for Alkaline Phosphatase2011
- Author(s)
  Mitsuyasu Kawaguchi, Kenjiro Hanaoka, Toru Komatsu, Takuya Terai, Tetsuo Nagano
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21 Issue: 17 Pages: 5088-5091
- DOI
  10.1016/j.bmcl.2011.03.070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000006
[Journal Article] Rational Design of Boron Dipyrromethene (BODIPY)-based Photobleaching-resistant Fluorophore Applicable to Protein Dynamics Study2011
- Author(s)
  Komatsu T., Oushiki D., Takeda A., Miyamura M., Ueno T., Terai T., Hanaoka K., Urano Y., Mineno T., Nagano T.
- Journal Title
  
  Chemical Communications
  
  Volume: 47 Issue: 36 Pages: 10055-10057
- DOI
  10.1039/c1cc13367e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10652, KAKENHI-PROJECT-22000006
[Journal Article] Fluorescence Probe for Lysophospholipase C/NPP6 Activity and a Potent NPP6 Inhibitor2011
- Author(s)
  Mitsuyasu Kawaguchi, Takayoshi Okabe, Shinichi, Okudaira, Kenjiro Hanaoka, Yuuta Fujikawa, Takuya Terai, Toru Komatsu, Hirotatsu Kojima, Junken Aoki, Tetsuo Nagano
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 133 Issue: 31 Pages: 12021-12030
- DOI
  10.1021/ja201028t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10632, KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23790071
[Journal Article] Development of a Highly Sensitive Fluorescence Probe for Hydrogen Peroxide2011
- Author(s)
  Masahiro Abo, et al
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 133 Issue: 27 Pages: 10629-10637
- DOI
  10.1021/ja203521e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10695, KAKENHI-PLANNED-20117003, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-23249004
[Journal Article] Synthetically rerouting phagocytosis by rapidly turning inert cells into"Eat you"mode
- Author(s)
  Hiroki Onuma, Toru Komatsu, Makoto Arita, Kenjiro Hanaoka, Tasuku Ueno, Takuya Terai, Tetsuo Nagano, Takanari Inoue
- Journal Title
  
  Science Signaling
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Selective ablation ofβ-galactosidase- expressing cells with a rationally designed activatable photosensitizer
- Author(s)
  Yuki Ichikawa, Mako Kamiya, Fumiaki Obata, Masayuki Miura, Takuya Terai, Toru Komatsu, Tasuku Ueno, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24655147
[Journal Article] Thermal or Mechanical Stimuli-induced Photoluminescence Color Chnage of Molecular Assembly Composed of An Amphiphilic Anthracene Derivative in Water
- Author(s)
  Yoshimitsu Sagara, Toru Komatsu, Takuya Terai, Tasuku Ueno, Kenjiro Hanaoka, Takashi Kato, and Tetsuo Nagano
- Journal Title
  
  Chemistry -A European Journal
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24655147
[Patent] 固相抽出を利用した蛍光プローブライブラリの調製方法、及びこれを用いた酵素活性計測方法2022
- Inventor(s)
  浦野泰照，小松徹，鏡味優，坂本眞伍，渡邉力也
- Industrial Property Rights Holder
  浦野泰照，小松徹，鏡味優，坂本眞伍，渡邉力也
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-23K23484
[Patent] 3.浦野泰照，小松徹，鏡味優，坂本眞伍，笠井貴文，渡邉力也2022
- Inventor(s)
  浦野泰照，小松徹，鏡味優，坂本眞伍，笠井貴文，渡邉力也
- Industrial Property Rights Holder
  浦野泰照，小松徹，鏡味優，坂本眞伍，笠井貴文，渡邉力也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-079082
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-23K23484
[Patent] 固相抽出を利用した蛍光プローブライブラリの調整方法、及びこれを用いた酵素活性計測方法2021
- Inventor(s)
  浦野泰照，小松徹，坂本眞伍，渡邉力也
- Industrial Property Rights Holder
  浦野泰照，小松徹，坂本眞伍，渡邉力也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-009683
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19H02846
[Patent] 固相抽出を利用した蛍光プローブライブラリの調整方法、及びこれを用いた酵素活性計測方法2021
- Inventor(s)
  浦野泰照，小松徹，坂本眞伍，渡邉力也
- Industrial Property Rights Holder
  浦野泰照，小松徹，坂本眞伍，渡邉力也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-009683
- Filing Date
  2021
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Patent] マイクロデバイスへの適合性の高い酵素活性可視化蛍光プローブ2017
- Inventor(s)
  浦野泰照，小松徹，坂本眞伍，野地博行，渡邊力也，張翼
- Industrial Property Rights Holder
  浦野泰照，小松徹，坂本眞伍，野地博行，渡邊力也，張翼
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-041149
- Filing Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-15K14937
[Patent] マイクロデバイスへの適合性の高い酵素活性可視化蛍光プローブ2017
- Inventor(s)
  浦野泰照，小松徹，坂本眞伍，野地博行，渡邊力也，張翼
- Industrial Property Rights Holder
  浦野泰照，小松徹，坂本眞伍，野地博行，渡邊力也，張翼
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-041149
- Filing Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-15H05371
[Patent] 細胞外代謝物を検出するための蛍光プローブ及び当該蛍光プローブを用いるスクリーニング方法2016
- Inventor(s)
  浦野泰照，小松徹，柳光一
- Industrial Property Rights Holder
  浦野泰照，小松徹，柳光一
- Industrial Property Rights Type
  特許
- Filing Date
  2016-11-22
- Overseas
- Data Source
  KAKENHI-PROJECT-15H05371
[Patent] 細胞外代謝物を検出するための蛍光プローブ及び当該蛍光プローブを用いるスクリーニング方法2016
- Inventor(s)
  浦野泰照，小松徹，柳光一
- Industrial Property Rights Holder
  浦野泰照，小松徹，柳光一
- Industrial Property Rights Type
  特許
- Filing Date
  2016-11-22
- Overseas
- Data Source
  KAKENHI-PROJECT-15K14937
[Patent] 酵素活性検出用2015
- Inventor(s)
  長野哲雄、花岡健二郎、小松徹、木村勇亮
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-02-25
- Data Source
  KAKENHI-PROJECT-22000006
[Patent] 酵素活性検出用試薬2014
- Inventor(s)
  長野哲雄,花岡健二郎,小松徹,木村勇亮
- Industrial Property Rights Holder
  長野哲雄,花岡健二郎,小松徹,木村勇亮
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-038427
- Filing Date
  2014-02-28
- Data Source
  KAKENHI-PROJECT-24655147
[Patent] 酵素活性検出用2014
- Inventor(s)
  長野哲雄、花岡健二郎、小松徹、木村勇亮
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-28
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] １分子レベルの酵素活性網羅的解析に基づく疾患診断技術基盤の開発と応用2023
- Author(s)
  小松徹
- Organizer
  バイオインタラクション（BIRA）研究会第 23 回ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] １分子レベルのタンパク質機能検出による疾患診断技術の開発2023
- Author(s)
  小松徹, 渡邉力也, 水野忠快, 本田一文, 坂本眞伍
- Organizer
  第 40 回メディシナルケミストリーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] Proteoform レベルの酵素活性網羅的解析に基づく疾患診断技術の開発2023
- Author(s)
  小松徹
- Organizer
  レドックス R&D 戦略委員会第 2 回夏のシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] Development of single-molecule enzyme activity profiling platform for activity-based diagnosis of early stage pancreatic tumor2023
- Author(s)
  Toru Komatsu
- Organizer
  国際交流シンポジウム次世代薬学アジアシンポジウム（日本薬学会第 144 年会）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] Proteoform レベルの酵素活性網羅的解析に基づく疾患診断技術の開発2023
- Author(s)
  小松徹
- Organizer
  第 1 回 ATF コンファレンス 2023年11月13日
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] 有機小分子蛍光プローブと１分子計測技術の融合による血液中１分子酵素活性網羅的解析技術の開発2023
- Author(s)
  小松徹
- Organizer
  日本薬学会第 144 年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] Development of single-molecule enzyme activity-based protein profiling (SEAP) strategy for the detection of disease-related enzyme activities in blood samples2022
- Author(s)
  Toru Komatsu, Shingo Sakamoto, Tadahaya Mizuno, Kazufumi Honda, Rikiya Watanabe, Yasuteru Urano
- Organizer
  Redox Week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] １分子レベルの酵素活性網羅的解析に基づく疾患診断技術の開発2022
- Author(s)
  小松徹
- Organizer
  千里ライフサイエンス振興財団新適塾「未来創薬への誘い」第57回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] 酵素のはたらきを網羅的に見て疾患を知る～１分子計測リキッドバイオプシー技術の確立を目指して～2022
- Author(s)
  小松徹
- Organizer
  2021 年度第 2 回バイオ単分子研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] １分子レベルの酵素活性網羅的解析に基づく疾患診断技術の開発2022
- Author(s)
  小松徹
- Organizer
  第 16 回メタボロームシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] Development of single-molecule enzyme activity-based protein profiling (SEAP) strategy for the detection of disease-related enzyme activities in blood samples2022
- Author(s)
  Toru Komatsu, Shingo Sakamoto, Yu Kagami, Tadahaya Mizuno, Kazufumi Honda, Rikiya Watanabe, Yasuteru Urano
- Organizer
  International Chemical Biology Society Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23484
[Presentation] 酵素活性の網羅的計測（enzymomics）による疾患関連タンパク質の探索2021
- Author(s)
  小松徹
- Organizer
  第71回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 酵素活性の網羅的計測（enzymomics）による疾患関連タンパク質の探索2021
- Author(s)
  小松徹
- Organizer
  第15回次世代を担う若手医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 抗体クリック反応による細胞表面選択的凝集による機能制御2021
- Author(s)
  小松徹, 姜悦, 石井遥暁, 山口藍子, 土釜恭直, 浦野泰照
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 抗体クリック反応による細胞表面選択的凝集による細胞機能制御2021
- Author(s)
  小松徹
- Organizer
  第 2 回発動分子科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 抗体クリック反応による細胞表面選択的凝集による機能制御2021
- Author(s)
  小松徹, 姜悦, 石井遥暁, 山口藍子, 土釜恭直, 浦野泰照
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 酵素活性の網羅的解析（enzymomics）による疾患関連タンパク質の探索2021
- Author(s)
  小松徹
- Organizer
  ３新学術領域合同シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 酵素活性の網羅的解析（enzymomics）による疾患関連タンパク質の探索2021
- Author(s)
  小松徹
- Organizer
  ３新学術領域合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] Diced electrophoresis gel アッセイ法を用いた疾患関連酵素の探索2021
- Author(s)
  小松徹
- Organizer
  2021 年度第 2 回バイオ単分子研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 血液中１分子酵素活性の網羅的検出による新規疾患関連酵素の探索2021
- Author(s)
  小松徹
- Organizer
  第75回日本口腔科学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 抗体クリック反応による細胞表面選択的凝集による細胞機能制御2021
- Author(s)
  小松徹
- Organizer
  第 2 回発動分子科学研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 酵素活性の網羅的計測（enzymomics）による疾患関連タンパク質の探索2021
- Author(s)
  小松徹
- Organizer
  第71回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 血液中１分子酵素活性の網羅的検出による新規疾患関連酵素の探索2021
- Author(s)
  小松徹
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 酵素活性の網羅的計測（enzymomics）による疾患関連タンパク質の探索2021
- Author(s)
  小松徹
- Organizer
  第15回次世代を担う若手医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] Development Of Enzymomics Approach To Search For Disease-Related Alternation Of Enzymatic Functions2020
- Author(s)
  Toru Komatsu
- Organizer
  iPoPS 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 酵素活性の網羅的解析（enzymomics）に基づく新規疾患診断技術の開発の試み2020
- Author(s)
  小松徹
- Organizer
  東北大学生命科学研究科生命科学 web セミナー（オンライン）
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] Development of Enzymomics Platform for Screening Altered Enzymatic Functions in Diseases2020
- Author(s)
  Toru Komatsu
- Organizer
  iPoPS 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 酵素活性の網羅的解析（enzymomics）に基づく新規疾患診断技術の開発の試み2020
- Author(s)
  小松徹
- Organizer
  東北大学生命科学研究科生命科学 web セミナー（オンライン）
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] Diced electrophoresis gel アッセイ法を用いた疾患関連酵素の探索2020
- Author(s)
  小松徹
- Organizer
  第71回日本電気泳動学会総会（オンライン開催）
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] Diced electrophoresis gel アッセイ法を用いた疾患関連酵素の探索2020
- Author(s)
  小松徹
- Organizer
  第71回日本電気泳動学会総会（オンライン開催）
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04694
[Presentation] 酵素活性の網羅的探索（enzymomics）に基づく疾患関連タンパク質の探索2019
- Author(s)
  小松徹
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] Diced electrophoresis gel 法を用いたがんにおけるペプチド代謝活性異常の網羅的解析2019
- Author(s)
  小松徹
- Organizer
  第69回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 緑茶カテキンによる細胞内「メチル化」状態の制御と健康寿命2019
- Author(s)
  小松徹
- Organizer
  科学的根拠に基づく健康寿命を延ばす会第15回講演・研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 物質代謝の局所性の制御と理解を目指すケミカルバイオロジー研究2019
- Author(s)
  小松徹
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] Diced electrophoresis gel 法を用いたがんにおけるペプチド代謝活性異常の網羅的解析2019
- Author(s)
  小松徹
- Organizer
  第69回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 酵素活性の網羅的探索（enzymomics）に基づく疾患関連タンパク質の探索2019
- Author(s)
  小松徹
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 疾患と関わるエピジェネティック代謝異常の天然物カテコールによる制御2019
- Author(s)
  小松徹
- Organizer
  2019年度さきがけ疾患代謝領域研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Diced electrophoresis gel 法を用いたがんにおけるペプチド代謝活性異常の網羅的解析2019
- Author(s)
  小松徹
- Organizer
  日本プロテオーム学会2019年大会／第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 緑茶カテキンによる細胞内「メチル化」状態の制御と健康寿命2019
- Author(s)
  小松徹
- Organizer
  科学的根拠に基づく健康寿命を延ばす会第15回講演・研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Diced electrophoresis gel 法を用いたがんにおけるペプチド代謝活性異常の網羅的解析2019
- Author(s)
  小松徹
- Organizer
  日本プロテオーム学会2019年大会／第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02846
[Presentation] 物質代謝の局所性の制御と理解を目指すケミカルバイオロジー研究2019
- Author(s)
  小松徹
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 酵素活性の網羅的探索（enzymomics）に基づく疾患関連タンパク質の探索2019
- Author(s)
  小松徹
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Diced electrophoresis gel 法を用いたがんにおけるペプチド代謝活性異常の網羅的解析2019
- Author(s)
  小松徹
- Organizer
  日本プロテオーム学会2019年大会／第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 緑茶カテキンによる細胞内「メチル化」状態の制御と健康寿命2019
- Author(s)
  小松徹
- Organizer
  科学的根拠に基づく健康寿命を延ばす会第15回講演・研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 物質代謝の局所性の制御と理解を目指すケミカルバイオロジー研究2019
- Author(s)
  小松徹
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 酵素活性の網羅的解析（enzymomics）による疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  レドックス研究会 2018
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 酵素活性の網羅的解析（enzymomics）による疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  レドックス研究会2018
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 酵素活性の網羅的評価（enzymomics）による新規疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Development of enzymomics approach to search for disease-related alternation of enzymatic functions2018
- Author(s)
  Toru Komatsu
- Organizer
  Mass Spectrometry and Proteomics (MSP) 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチド代謝活性の網羅的解析（enzymomics）による新規疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」第1回若手シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] ペプチド代謝活性の網羅的解析（enzymomics）による疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  第69回日本電気泳動学会総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 有機小分子蛍光プローブを用いた SAM高感度検出系の開発とその応用2018
- Author(s)
  荻原州介、小松徹、浦野泰照
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 酵素のはたらきを「視る」手法を開発して新たな疾患関連タンパク質を「探す」2018
- Author(s)
  小松徹
- Organizer
  ITbM/IGER Chemistry Workshop 2018 - Exploring the Science with Molecules
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Development of enzymomics approach to search for disease-related alternation of enzymatic functions2018
- Author(s)
  Toru Komatsu
- Organizer
  ICPAC Langkawi 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] マイクロデバイスを用いた単一酵素活性検出による病態診断法の開発2018
- Author(s)
  坂本眞伍、小松徹、渡邉力也、張翼、野地博行、浦野泰照
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 酵素活性の網羅的評価（enzymomics）による新規疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] Development Of Enzymomics Approach To Search For Disease-Related Alternation Of Enzymatic Functions2018
- Author(s)
  Toru Komatsu
- Organizer
  ICPAC Langkawi 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] Diced Electrophoresis Gel (DEG) 法を用いた癌細胞における活性異常酵素の探索2018
- Author(s)
  小松徹
- Organizer
  第38回キャピラリー電気泳動シンポジウム (SCE2018)
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] Discovery of Disease-related Alternation of Enzymatic Functions with Enzymomics Approach2018
- Author(s)
  Toru Komatsu, Jun Onagi, Yuki Ichikawa, Yasuteru Urano
- Organizer
  日本化学会第98年春季大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチド代謝活性の網羅的解析（enzymomics）による新規疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」第1回若手シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 酵素活性の網羅的解析（Enzymomics）法による疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  第56回生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 分子夾雑の理解に基づく癌関連タンパク質のオルガネラ膜局時局在機構の解明と制御2018
- Author(s)
  小松徹
- Organizer
  新学術領域研究「分子夾雑の生命化学」関東地区シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] マイクロデバイスを用いた単一酵素活性検出による病態診断法の開発2018
- Author(s)
  坂本眞伍、小松徹、渡邉力也、張翼、野地博行、浦野泰照
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Discovery of Disease-related Alternation of Enzymatic Functions with Enzymomics Approach2018
- Author(s)
  Toru Komatsu, Jun Onagi, Yuki Ichikawa, Yasuteru Urano
- Organizer
  日本化学会第98年春季大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 酵素活性の網羅的解析（Enzymomics）法による疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  第56回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] ペプチド代謝活性の網羅的解析(enzymomics)による疾患関連タンパク質の探索2018
- Author(s)
  小松徹
- Organizer
  第69回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 分子夾雑の理解に基づく癌関連タンパク質のオルガネラ膜局時局在機構の解明と制御2018
- Author(s)
  小松徹
- Organizer
  新学術領域研究「分子夾雑の生命化学」関東地区シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] 酵素のはたらきを「視る」手法を開発して新たな疾患関連タンパク質を「探す」2018
- Author(s)
  小松徹
- Organizer
  ITbM/IGER Chemistry Workshop 2018 - Exploring the Science with Molecules
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] Development of enzymomics approach to search for disease-related alternation of enzymatic functions2018
- Author(s)
  小松徹
- Organizer
  Mass Spectrometry and Proteomics 2018 (MSP2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04538
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2018
- Author(s)
  柳光一、小松徹、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Diced Electrophoresis Gel (DEG) 法を用いた癌細胞における活性異常酵素の探索2018
- Author(s)
  小松徹
- Organizer
  第38回キャピラリー電気泳動シンポジウム (SCE2018)
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2018
- Author(s)
  柳光一、小松徹、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチドライブラリーを用いたenzymomicsプラットフォームの構築2017
- Author(s)
  小松徹、小名木淳、市橋裕樹、浦野泰照
- Organizer
  第68回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2017
- Author(s)
  柳光一、小松徹、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチドライブラリーを用いたenzymomicsプラットフォームの構築2017
- Author(s)
  小松徹、小名木淳、市橋裕樹、浦野泰照
- Organizer
  第68回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 酵素の動的機能の理解による疾患関連タンパク質の探索2017
- Author(s)
  小松徹
- Organizer
  第30回バイオメディカル分析科学シンポジウム(BMAS2017)
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] マイクロデバイスを用いた単一酵素活性検出による病態診断法の開発2017
- Author(s)
  坂本眞伍、小松徹、渡邉力也、張翼、野地博行、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12回年会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Diced Electrophoresis Gel (DICE) 法を用いた癌細胞における機能異常酵素の探索2017
- Author(s)
  小松徹、小名木淳、市橋裕樹、浦野泰照
- Organizer
  日本プロテオーム学会2017年大会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 酵素の動的機能の理解に基づく疾患関連タンパク質の探索と機能評価2017
- Author(s)
  小松徹
- Organizer
  "新学術領域「柔らかな分子系」第20回ワークショップ「構造変化で操る分子の機能」"
- Place of Presentation
  東京大学（東京都文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Development of enzymomics approach to search for disease-related alternation of enzymatic functions2017
- Author(s)
  Toru Komatsu, Jun Onagi, Yuki Ichihashi, Tetsuo Nagano and Yasuteru Urano
- Organizer
  International Chemical Biology Society 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Development of enzymomicsapproach to search for disease-related alternation of enzymatic functions2017
- Author(s)
  Toru Komatsu, Jun Onagi, Yuki Ichihashi, Tetsuo Nagano and Yasuteru Urano
- Organizer
  The Second International Symposium on Biofunctional Chemistry (ISBC 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 疾患関連酵素を探す、視る、操るケミカルバイオロジー研究2017
- Author(s)
  小松徹
- Organizer
  第11回名市大頭脳循環セミナー
- Place of Presentation
  名古屋市立大学（愛知県名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 蛍光物質Boron dipyrromethene (BODIPY) 2,6位化学修飾新規蛍光群開発2017
- Author(s)
  小松徹、Cherythu Nusaiba MADAPPURAM、浦野泰照
- Organizer
  生体機能関連化学部会若手の会第29回サマースクール
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Pathway-oriented screening法による癌細胞の代謝制御化合物の探索2017
- Author(s)
  小松徹、柳光一、荻原洲介、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  ConBio2017(生命科学系合同年次大会) （第40回日本分子生物学会年会、第90回日本生化学大会）
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 疾患関連酵素を探す、視る、操るケミカルバイオロジー研究ツールの開発2017
- Author(s)
  小松徹
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Development of enzymomicsapproach to search for disease-related alternation of enzymatic functions2017
- Author(s)
  Toru Komatsu, Jun Onagi, Yuki Ichihashi, Tetsuo Nagano and Yasuteru Urano
- Organizer
  The Second International Symposium on Biofunctional Chemistry (ISBC 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Development of enzymomics approach to search for disease-related alternation of enzymatic functions2017
- Author(s)
  Toru Komatsu, Jun Onagi, Yuki Ichihashi, Tetsuo Nagano and Yasuteru Urano
- Organizer
  International Chemical Biology Society Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 酵素の動的機能の理解に基づく疾患関連タンパク質の探索と機能評価2017
- Author(s)
  小松徹
- Organizer
  "新学術領域「柔らかな分子系」第20回ワークショップ「構造変化で操る分子の機能」"
- Place of Presentation
  東京大学（東京都文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2017
- Author(s)
  柳光一、小松徹、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] ペプチドライブラリーを用いた酵素活性の網羅的解析法の確立と発展2017
- Author(s)
  市橋裕樹、小名木淳、小松徹、神谷真子、松崎裕幸、畑啓介、渡邉聡明、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12年会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチドライブラリーを用いた酵素活性の網羅的解析法の確立と発展2017
- Author(s)
  市橋裕樹、小名木淳、小松徹、神谷真子、松崎裕幸、畑啓介、渡邉聡明、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12回年会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] ペプチドライブラリーを用いた疾患関連酵素の探索2017
- Author(s)
  市橋裕樹，小名木淳，小松徹，浦野泰照
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] マイクロデバイスを用いた一酵素活性の高精度解析による新規病態診断法の開発2017
- Author(s)
  坂本眞伍，小松徹，張翼，渡邉力也，野地博行，浦野泰照
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 生細胞系代謝スクリーニング法の開発による新規解糖系阻害剤群の探索2017
- Author(s)
  柳光一，小松徹，浦野泰照
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 新規Activatable型Carboxypeptidase活性検出蛍光プローブの開発と応用2017
- Author(s)
  栗木優五、神谷真子、小松徹、上野匡、山下俊、國土典宏、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12年会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 生細胞系代謝スクリーニング法の開発による新規解糖系阻害剤群の探索2017
- Author(s)
  柳光一，小松徹，浦野泰照
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 疾患関連酵素を探す、視る、操るケミカルバイオロジー研究ツールの開発2017
- Author(s)
  小松徹
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] ペプチドの「代謝」を視る技術を開発し新たな疾患関連タンパク質の機能を解明する2017
- Author(s)
  小松徹
- Organizer
  第49回若手ペプチド夏の勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 疾患関連酵素を探す、視る、操るケミカルバイオロジー研究2017
- Author(s)
  小松徹
- Organizer
  第11回名市大頭脳循環セミナー
- Place of Presentation
  名古屋市立大学（愛知県名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] マイクロデバイス中の単一酵素活性検出による病態診断法の開発2017
- Author(s)
  坂本眞伍、小松徹、渡邉力也、張翼、野地博行、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12年会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2017
- Author(s)
  柳光一、小松徹、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12年会
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチドの「代謝」を視る技術を開発し新たな疾患関連タンパク質の機能を解明する2017
- Author(s)
  小松徹
- Organizer
  第49回若手ペプチド夏の勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2017
- Author(s)
  柳光一、小松徹、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第12回年会
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 蛍光物質Boron dipyrromethene (BODIPY) 2,6位化学修飾新規蛍光群開発2017
- Author(s)
  小松徹、Cherythu Nusaiba MADAPPURAM、浦野泰照
- Organizer
  生体機能関連化学部会若手の会第29回サマースクール
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチドライブラリーを用いた酵素活性の網羅的解析法の確立と発展2017
- Author(s)
  市橋裕樹、小名木淳、小松徹、神谷真子、松崎裕幸、畑啓介、渡邉聡明、浦野泰照
- Organizer
  ConBio2017(生命科学系合同年次大会) （第40回日本分子生物学会年会、第90回日本生化学大会）
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] ペプチドライブラリーを用いた疾患関連酵素の探索2017
- Author(s)
  市橋裕樹，小名木淳，小松徹，浦野泰照
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Development of activatable fluorescent probes for carboxypeptidase and their application2017
- Author(s)
  Yugo Kuriki, Mako Kamiya, Hidemasa Kubo, Toru Komatsu, Tasuku Ueno, Suguru Yamashita, Norihiro Kokudo and Yasuteru Urano
- Organizer
  The Second International Symposium on Biofunctional Chemistry (ISBC 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] Pathway-oriented screening法による解糖系酵素阻害剤の探索2017
- Author(s)
  柳光一, 小松徹, 小島宏建, 岡部隆義, 長野哲雄, 浦野泰照
- Organizer
  ConBio2017(生命科学系合同年次大会) （第40回日本分子生物学会年会、第90回日本生化学大会）
- Data Source
  KAKENHI-PROJECT-17K19477
[Presentation] 酵素の動的機能の理解による疾患関連タンパク質の探索2017
- Author(s)
  小松徹
- Organizer
  第30回バイオメディカル分析科学シンポジウム(BMAS2017)
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Pathway-oriented screening法による癌細胞の代謝制御化合物の探索2017
- Author(s)
  小松徹、柳光一、荻原洲介、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  "ConBio2017(生命科学系合同年次大会) （第40回日本分子生物学会年会、第90回日本生化学大会）"
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] マイクロデバイスを用いた一酵素活性の高精度解析による新規病態診断法の開発2017
- Author(s)
  坂本眞伍，小松徹，張翼，渡邉力也，野地博行，浦野泰照
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] S-adenosyl-L-methionine(SAM)の高感度検出に基づく細胞内メチオニン代謝活性のハイスループット評価系の開発2017
- Author(s)
  小松徹、荻原洲介、木村勇亮、浦野泰照
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 酵素活性の理解に基づく新規疾患関連タンパク質探索法の開発2016
- Author(s)
  小松徹，小名木淳，柳光一，長野哲雄，浦野泰照
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 小分子代謝・輸送過程の新規評価系の構築2016
- Author(s)
  柳光一、小松徹、浦野泰照
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 疾患関連タンパク質探索のための酵素活性の網羅的計測（enzymomics）技術の開発2016
- Author(s)
  小松徹，小名木淳，柳光一，花岡健二郎，浦野泰照
- Organizer
  日本分析化学会第65年会
- Place of Presentation
  北海道大学（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 酵素活性の理解に基づく新規疾患関連タンパク質探索法の開発2016
- Author(s)
  小松徹，小名木淳，柳光一，長野哲雄，浦野泰照
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Diced Electrophoresis Gel（DEG）アッセイ法を用いた癌細胞における活性異常酵素の探索2016
- Author(s)
  小名木淳，小松徹，花岡健二郎，長野哲雄，浦野泰照
- Organizer
  生体機能関連化学部会若手の会サマースクール
- Place of Presentation
  西浦温泉ホテルたつき（愛知県蒲郡市）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 細胞外代謝物の高感度検出による代謝過程制御化合物の探索2016
- Author(s)
  柳光一，小松徹，浦野泰照
- Organizer
  生体機能関連化学部会若手の会サマースクール
- Place of Presentation
  西浦温泉ホテルたつき（愛知県蒲郡市）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 新規癌イメージングプローブ開発を指向した蛍光プローブライブラリーの創製2016
- Author(s)
  栗木優五、神谷真子、小松徹、居軒和也、高丸博之、阿部清一郎、斎藤豊、浦野泰照
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Diced Electrophoresis Gel（DEG）アッセイ法を用いた癌細胞における活性異常酵素の探索2016
- Author(s)
  小名木淳，小松徹，花岡健二郎，長野哲雄，浦野泰照
- Organizer
  生体機能関連化学部会若手の会サマースクール
- Place of Presentation
  西浦温泉ホテルたつき（愛知県蒲郡市）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Discovery of Disease-related Protein Functions with High Throughput Global Evaluation of Enzymatic Activities2016
- Author(s)
  Toru Komatsu, Jun Onagi, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Organizer
  ICBS Meeting 2016
- Place of Presentation
  Univ. Wisconsin, Madison (Wisconsin, USA)
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 細胞外代謝物の高感度検出による代謝過程制御化合物の探索2016
- Author(s)
  柳光一，小松徹，浦野泰照
- Organizer
  生体機能関連化学部会若手の会サマースクール
- Place of Presentation
  西浦温泉ホテルたつき（愛知県蒲郡市）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 新規癌イメージングプローブ開発を指向した蛍光プローブライブラリーの創製2016
- Author(s)
  栗木優五、神谷真子、小松徹、居軒和也、高丸博之、阿部清一郎、斎藤豊、浦野泰照
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 小分子代謝・輸送過程の新規評価系の構築2016
- Author(s)
  柳光一、小松徹、浦野泰照
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 疾患関連タンパク質探索のための酵素活性の網羅的計測（enzymomics）技術の開発2016
- Author(s)
  小松徹，小名木淳，柳光一，花岡健二郎，浦野泰照
- Organizer
  日本分析化学会第65年会
- Place of Presentation
  北海道大学（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 疾患関連タンパク質探索のための酵素活性の網羅的計測（enzymomics）技術の開発2016
- Author(s)
  小松徹，小名木淳，花岡健二郎，長野哲雄，浦野泰照
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子蛍光プローブを用いた創薬標的酵素の探索と機能評価2016
- Author(s)
  小松徹
- Organizer
  第89回日本生化学会シンポジウム「アカデミア発創薬探索研究」
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子を使って酵素を探す、酵素を視る2016
- Author(s)
  小松徹
- Organizer
  第一回BRIGHTシンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 疾患関連タンパク質探索のための酵素活性の網羅的計測（enzymomics）技術の開発2016
- Author(s)
  小松徹，小名木淳，花岡健二郎，長野哲雄，浦野泰照
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Discovery of Disease-related Protein Functions with High Throughput Global Evaluation of Enzymatic Activities2016
- Author(s)
  Toru Komatsu, Jun Onagi, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Organizer
  ICBS Meeting 2016
- Place of Presentation
  Univ. Wisconsin, Madison (Wisconsin, USA)
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Diced Electrophoresis Gel（DEG）アッセイ法を用いた癌細胞における活性異常酵素の探索2016
- Author(s)
  小松徹，吉岡健太郎，花岡健二郎，長野哲雄，浦野泰照
- Organizer
  第67回日本電気泳動学会総会
- Place of Presentation
  釧路市観光国際交流センター（北海道釧路市）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Diced Electrophoresis Gel（DEG）アッセイ法を用いた癌細胞における活性異常酵素の探索2016
- Author(s)
  小松徹，吉岡健太郎，花岡健二郎，長野哲雄，浦野泰照
- Organizer
  第67回日本電気泳動学会総会
- Place of Presentation
  釧路市観光国際交流センター（北海道釧路市）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 有機小分子を使って酵素を探す、酵素を視る2016
- Author(s)
  小松徹
- Organizer
  第一回BRIGHTシンポジウム
- Place of Presentation
  徳島大学（徳島県徳島市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 有機小分子蛍光プローブを用いた創薬標的酵素の探索と機能評価2016
- Author(s)
  小松徹
- Organizer
  第89回日本生化学会シンポジウム「アカデミア発創薬探索研究」
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] ペプチドライブラリーを用いた酵素活性の網羅的解析法の開発2015
- Author(s)
  小名木淳、小松徹、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台市（東北大学川内キャンパス）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 有機小分子蛍光プローブを用いたメチル基転移酵素活性の高感度検出法の開発と阻害剤探索2015
- Author(s)
  小松徹，木村勇亮，花岡健二郎，小島宏建，岡部隆義，長野哲雄，浦野泰照
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉市（幕張国際研修センター）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] A novel cancer imaging technology by constructiong a fluorescent probe library2015
- Author(s)
  Yugo Kuriki, Mako Kamiya, Haruna Onoyama, Toru Komatsu, Yasuyuki Seto,Yasuteru Urano
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市（平塚市中央公民館）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子蛍光プローブを用いたメチル基転移酵素活性の高感度検出法の開発と阻害剤探索2015
- Author(s)
  小松徹，木村勇亮，花岡健二郎，小島宏建，岡部隆義，長野哲雄，浦野泰照
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  千葉市（幕張国際研修センター）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子蛍光プローブを用いたペプチドisoaspartyl基のメチル化活性の高感度検出2015
- Author(s)
  小松徹，木村勇亮，花岡健二郎，小島宏建，岡部隆義，長野哲雄，浦野泰照
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市（平塚市中央公民館）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Diced Electrophoresis Gel Assay（DEG）法を用いた新規創薬標的タンパク質の探索2015
- Author(s)
  小松徹
- Organizer
  第66回日本電気泳動学会総会
- Place of Presentation
  大田区（東京工科大学蒲田キャンパス）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子蛍光プローブを用いたペプチドisoaspartyl基のメチル化活性の高感度検出2015
- Author(s)
  小松徹，木村勇亮，花岡健二郎，小島宏建，岡部隆義，長野哲雄，浦野泰照
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市（平塚市中央公民館）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 癌関連タンパク質Protein L-isoaspartyl methyltransferaseの活性評価法および活性制御化合物の開発2015
- Author(s)
  木村勇亮、小松徹、小名木淳、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台市（東北大学川内キャンパス）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] NADH検出蛍光プローブを用いたWarburg効果関連タンパク質阻害剤スクリーニング系2015
- Author(s)
  柳光一，小松徹，浦野泰照
- Organizer
  第6回スクリーニング学研究会
- Place of Presentation
  大宮市（ソニックシティ大宮）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Diced Electrophoresis Gel Assay（DEG）法を用いた新規創薬標的タンパク質の探索2015
- Author(s)
  小松徹
- Organizer
  第66回日本電気泳動学会総会
- Place of Presentation
  大田区（東京工科大学蒲田キャンパス）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] "Synthetically Rerouting Phagocytosis by Rapidly Turning Inert Cells into “Eat You” Mode"2015
- Author(s)
  Toru Komatsu
- Organizer
  New Biological Frontiers Illuminated by Molecular Sensors and Actuators
- Place of Presentation
  台北（台湾）
- Year and Date
  2015-06-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Diced electrophoresis gel assay for screening enzymes with specified activities2015
- Author(s)
  Toru Komatsu, Jun Onagi, Akihiko Nakada, Tetsuo Nagano, Yasuteru Urano
- Organizer
  Pacifichem 2015
- Place of Presentation
  ホノルル（アメリカ）
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] NADH検出蛍光プローブを用いたWarburg効果関連タンパク質阻害剤スクリーニング系2015
- Author(s)
  柳光一，小松徹，浦野泰照
- Organizer
  第6回スクリーニング学研究会
- Place of Presentation
  大宮市（ソニックシティ大宮）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] A novel cancer imaging technology by constructiong a fluorescent probe library2015
- Author(s)
  Yugo Kuriki, Mako Kamiya, Haruna Onoyama, Toru Komatsu, Yasuyuki Seto,Yasuteru Urano
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市（平塚市中央公民館）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 癌関連タンパク質Protein L-isoaspartyl methyltransferaseの活性評価法および活性制御化合物の開発2015
- Author(s)
  木村勇亮、小松徹、小名木淳、小島宏建、岡部隆義、長野哲雄、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台市（東北大学川内キャンパス）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 蛍光プローブライブラリー創製による新規迅速癌イメージングの実現2015
- Author(s)
  栗木優五、神谷真子、小野山温那、小松徹、瀬戸泰之、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台市（東北大学川内キャンパス）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 蛍光プローブライブラリー創製による新規迅速癌イメージングの実現2015
- Author(s)
  栗木優五、神谷真子、小野山温那、小松徹、瀬戸泰之、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台市（東北大学川内キャンパス）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Synthetic reconstitution of phagocytosis by chemically induced modification of cell-cell interaction2015
- Author(s)
  Toru Komatsu
- Organizer
  ECBS & ICBS 2015
- Place of Presentation
  ベルリン（ドイツ）
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Synthetic reconstitution of phagocytosis by chemically induced modification of cell-cell interaction2015
- Author(s)
  Toru Komatsu
- Organizer
  ECBS & ICBS2015
- Place of Presentation
  ベルリン（ドイツ）
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] "Synthetically Rerouting Phagocytosis by Rapidly Turning Inert Cells into “Eat You” Mode"2015
- Author(s)
  Toru Komatsu
- Organizer
  New Biological Frontiers Illuminated by Molecular Sensors and Actuators
- Place of Presentation
  台北（台湾）
- Year and Date
  2015-06-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 蛍光プローブライブラリーの創製による新規迅速癌イメージングの実現2015
- Author(s)
  栗木優五、神谷真子、小野山温那、小松徹、瀬戸泰之、浦野泰照
- Organizer
  第10回日本分子イメージング学会学術集会
- Place of Presentation
  江戸川区（タワーホール船堀）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] Diced electrophoresis gel assay for screening enzymes with specified activities2015
- Author(s)
  Toru Komatsu, Jun Onagi, Akihiko Nakada, Tetsuo Nagano, Yasuteru Urano
- Organizer
  Pacifichem 2015
- Place of Presentation
  ホノルル（ハワイ）
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] ペプチドライブラリーを用いた酵素活性の網羅的解析法の開発2015
- Author(s)
  小名木淳、小松徹、浦野泰照
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  仙台市（東北大学川内キャンパス）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子蛍光プローブを用いたペプチドisoaspartyl基のメチル化活性の高感度検出2015
- Author(s)
  小松徹，木村勇亮，花岡健二郎，小島宏建，岡部隆義，長野哲雄，浦野泰照
- Organizer
  第6回スクリーニング学研究会
- Place of Presentation
  大宮市（ソニックシティ大宮）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K14937
[Presentation] 有機小分子蛍光プローブを用いたペプチドisoaspartyl基のメチル化活性の高感度検出2015
- Author(s)
  小松徹，木村勇亮，花岡健二郎，小島宏建，岡部隆義，長野哲雄，浦野泰照
- Organizer
  第6回スクリーニング学研究会
- Place of Presentation
  大宮市（ソニックシティ大宮）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] 蛍光プローブライブラリーの創製による新規迅速癌イメージングの実現2015
- Author(s)
  栗木優五、神谷真子、小野山温那、小松徹、瀬戸泰之、浦野泰照
- Organizer
  第10回日本分子イメージング学会学術集会
- Place of Presentation
  江戸川区（タワーホール船堀）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15H05371
[Presentation] Diced Electrophoresis Gel (DEG)アッセイ法を用いた酸化損傷タンパク質代謝酵素の探索2014
- Author(s)
  吉岡健太郎、小松徹、長野哲雄、花岡健二郎、浦野泰照
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県(熊本市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] Protein L-isoaspartyl methyltransferase (PIMT)の新規活性検出系の開発2014
- Author(s)
  木村勇亮、小松徹、長野哲雄、花岡健二郎、浦野泰照
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] Diced Electrophoresis Gel（DEG）アッセイ法を用いた酸化損傷タンパク質代謝酵素の探索2014
- Author(s)
  吉岡健太郎、小松徹、長野哲雄、花岡健二郎、浦野泰照
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] Protein L-isoaspartyl methyltransferase (PIMT)の新規活性検出系の開発2014
- Author(s)
  木村勇亮、小松徹、長野哲雄、花岡健二郎、浦野泰照
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県(熊本市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による細胞膜外フェノタイプ制御法の開発と応用2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による膜輸送制御に基づく細胞表面機能の改変2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第7回バイオ関連化学合同シンポジウム2013
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 酸化損傷タンパク質代謝酵素の探索を目的とした有機小分子蛍光プローブの開発2013
- Author(s)
  吉岡健太郎、小松徹、長野哲雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 酵素活性可視化蛍光プローブの標的タンパク質の同定と機能評価2013
- Author(s)
  小松徹、川口充康、吉岡健太郎、長野哲雄
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  鳥取県(鳥取市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による膜輸送制御に基づく細胞接着能の改変2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第1回バイオ関連化学シンポジウム若手フォーラム
- Place of Presentation
  愛知県(名古屋市)
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 生体内の代謝活性を可視化する有機小分子蛍光プローブを用いた酵素の網羅的探索法の開発2013
- Author(s)
  小松徹、川口充康、吉岡健太郎、花岡健二郎、長野哲雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県(神戸市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 酵素活性可視化蛍光プローブの標的タンパク質の同定と機能評価2013
- Author(s)
  小松徹、川口充康、吉岡健太郎、長野哲雄
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による細胞膜外フェノタイプ制御法の開発と応用2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京都(文京区)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質代謝酵素の探索2013
- Author(s)
  吉岡健太郎、小松徹、花岡健二郎、長野哲雄
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県(横浜市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質代謝酵素の探索2013
- Author(s)
  吉岡健太郎, 小松徹、花岡健二郎、長野哲雄
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京都(文京区)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 蛍光プローブの分子標的探索法の開発による疾患バイオマーカー酵素の探索2013
- Author(s)
  小松徹、川口充康、吉岡健太郎、花岡健二郎、長野哲雄
- Organizer
  第7回バイオ関連化学合同シンポジウム2013
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質代謝酵素の探索2013
- Author(s)
  吉岡健太郎、小松徹、花岡健二郎、長野哲雄
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による細胞表面機能の改変を可能にするCISD法の開発と細胞接着への応用2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県(神戸市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 蛍光プローブの分子標的探索法の開発による疾患バイオマーカー酵素の探索2013
- Author(s)
  小松徹、川口充康、吉岡健太郎、花岡健二郎、長野哲雄
- Organizer
  第7回バイオ関連化学合同シンポジウム2013
- Place of Presentation
  愛知県(名古屋市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による膜輸送制御に基づく細胞接着能の改変2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第1回バイオ関連化学シンポジウム　若手フォーラム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いたホルミル化ペプチド代謝酵素の探索と機能評価2013
- Author(s)
  小松徹、川口充康、長野哲雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による細胞表面機能の改変を可能にするCISD法の開発と細胞接着への応用2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いたホルミル化ペプチド代謝酵素の探索と機能評価2013
- Author(s)
  小松徹，川口充康，長野哲雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質代謝酵素の探索2013
- Author(s)
  吉岡健太郎、小松徹、花岡健二郎、長野哲雄
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による細胞膜外フェノタイプ制御法の開発と応用2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県(横浜市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による細胞膜外フェノタイプ制御法の開発と応用2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質代謝酵素の探索2013
- Author(s)
  吉岡健太郎，小松徹，長野哲雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 生体内の代謝活性を可視化する有機小分子蛍光プローブを用いた酵素の網羅的探索法の開発2013
- Author(s)
  小松徹、川口充康、吉岡健太郎、花岡健二郎、長野哲雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による膜輸送制御に基づく細胞表面機能の改変2013
- Author(s)
  大沼裕樹、小松徹、花岡健二郎、長野哲雄、井上尊生
- Organizer
  第7回バイオ関連化学合同シンポジウム2013
- Place of Presentation
  愛知県(名古屋市)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 分子間光誘起電子移動を用いたインテグリンリガンドアナログの結合依存的な蛍光強度制御2012
- Author(s)
  竹田碧、小松徹、長野哲雄
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] インテグリンαVβ3の活性を検出する小分子蛍光プローブ2012
- Author(s)
  竹田碧、小松徹、長野哲雄
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 活性型Integrin αvβ_3を検出する小分子蛍光プローブの開発2012
- Author(s)
  竹田碧、小松徹、長野哲雄
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いたN末端ホルミル化ペプチド代謝酵素の探索と活性イメージングによる機能評価2012
- Author(s)
  小松徹，川口充康，長野哲雄
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酵素活性検出法によるホルミル化ペプチド代謝酵素の探索と機能評価2012
- Author(s)
  小松徹、川口充康、長野哲雄
- Organizer
  第30回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いたＮ末端ホルミル化ペプチド代謝酵素の探索と活性イメージングによる機能評価2012
- Author(s)
  小松徹、川口充康、長野哲雄
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いた電気泳動ゲル内酵素アッセイ法による細胞内酵素活性の網羅的解析2012
- Author(s)
  小松徹、川口充康、長野哲雄
- Organizer
  日本プロテオーム学会2012年大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いた電気泳動ゲル内酵素アッセイ法による細胞内酵素活性の網羅的解析2012
- Author(s)
  小松徹，川口充康，長野哲雄
- Organizer
  日本プロテオーム学会 2012年大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 電気泳動による分離に基づく酵素アッセイ法による好中球走化性因子の代謝酵素の探索と機能評価2012
- Author(s)
  小松徹、川口充康、長野哲雄
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 電気泳動による分離に基づく酵素アッセイ法による有機小分子蛍光プローブの新規標的タンパク質の同定と解析2012
- Author(s)
  小松徹，川口充康，長野哲雄
- Organizer
  日本ケミカルバイオロジー学会第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] Fluorescence probe for Lysophospholipase C/NPP6 and Its Inhibitor Screening2011
- Author(s)
  Mitsuyasu Kawaguchi, Takayoshi Okabe, Shinichi Okudaira, Kenjiro Hanaoka, Yuuta Fujikawa, Takuya Terai, Toru Komatsu, Hirotatsu Kojima, Junken Aoki, Tetsuo Nagano
- Organizer
  Gordon Research Conference on Bioorganic Chemistry
- Place of Presentation
  アメリカ(ニューハンプシャー)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] Fluorescence imaging-based analysis of protein dynamio using protein labeling small molecular probes2011
- Author(s)
  Toru Komatsu, Kai Johnsson, Hiroyuki Okuno, Haruhiko Bito, Takanari Inoue, Tetsuo Nagano, Yasuteru Urano
- Organizer
  WMIC2011
- Place of Presentation
  アメリカ(サンディエゴ)
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブによる代謝活性可視化を利用した新規酵素活性の探索手法の開発
- Author(s)
  小松徹、吉岡健太郎、小名木淳、花岡健二郎、長野哲雄、浦野泰照
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  兵庫県(神戸市)神戸国際会議場
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] Diced Electrophoresis Gel (DEG)アッセイ法を用いた酸化損傷タンパク質代謝酵素の探索
- Author(s)
  吉岡健太郎,小松徹,長野哲雄,花岡健二郎,浦野泰照
- Organizer
  日本薬学会第134年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質の探索
- Author(s)
  吉岡健太郎,小松徹,花岡健二郎,長野哲雄
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子を用いた膜輸送制御によるファゴサイトーシス様機能の再構築
- Author(s)
  小松徹、大沼裕樹、浦野泰照、花岡健二郎、長野哲雄、井上尊生
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪府(豊中市)大阪大学豊中キャンパス
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブによる代謝活性可視化を利用した酵素の探索手法の開発
- Author(s)
  小松徹、花岡健二郎、長野哲雄、浦野泰照
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  茨城県(つくば市)つくば国際会議場
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子蛍光プローブを用いた電気泳動ゲル内酵素アッセイ法による細胞内酵素活性の網羅的解析
- Author(s)
  小松徹,川口充康,長野哲雄
- Organizer
  日本プロテオーム学会2012年大会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いたN末端ホルミル化ペプチド代謝酵素の探索と活性イメージングによる機能評価
- Author(s)
  小松徹,川口充康,吉岡健太郎,長野哲雄
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による膜輸送制御に基づく細胞接着能の改変
- Author(s)
  大沼裕樹,小松徹,花岡健二郎,長野哲雄,井上尊生
- Organizer
  第1回バイオ関連化学シンポジウム若手フォーラム
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による膜輸送制御に基づく細胞接着能の改変
- Author(s)
  大沼裕樹,小松徹,花岡健二郎,長野哲雄,井上尊生
- Organizer
  第7回バイオ関連化学シンポジウム
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブライブラリーを用いた代謝酵素探索法の開発とピルビン酸アミド構造の代謝に関わる酵素機能の評価
- Author(s)
  吉岡健太郎、小松徹、花岡健二郎、長野哲雄、浦野泰照
- Organizer
  第67回日本酸化ストレス学会学術集会
- Place of Presentation
  京都府(京都市)同志社大学
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 生体内の代謝活性を可視化する有機小分子蛍光プローブを用いた酵素の網羅的探索法の開発
- Author(s)
  小松徹,川口充康,吉岡健太郎,花岡健二郎,長野哲雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 非変性電気泳動に基づく高感度酵素アッセイ法の開発とバイオマーカー探索への応用
- Author(s)
  小松徹、吉岡健太郎、花岡健二郎、長野哲雄、浦野泰照
- Organizer
  第65回日本電気泳動学会総会
- Place of Presentation
  神奈川県(横浜市)横浜情報文化センター
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 電気泳動による分離に基づく酵素アッセイ法による有機小分子蛍光プローブの新規標的タンパク質の同定と解析
- Author(s)
  小松徹,川口充康,長野哲雄
- Organizer
  日本ケミカルバイオロジー学会第7回年回
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 蛍光プローブの分子標的探索法の開発による疾患バイオマーカー酵素の探索
- Author(s)
  小松徹,川口充康,吉岡健太郎,花岡健二郎,長野哲雄
- Organizer
  第7回バイオ関連化学シンポジウム
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] Proten L-isoaspartyl methyltransferase (PIMT)の新規活性検出系の開発
- Author(s)
  木村勇亮、小松徹、花岡健二郎、長野哲雄、浦野泰照
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  兵庫県(神戸市)神戸国際会議場
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による膜輸送制御を可能にするCISD法の開発と細胞接着への応用
- Author(s)
  大沼裕樹,小松徹,花岡健二郎,長野哲雄,井上尊生
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質の探索
- Author(s)
  吉岡健太郎,小松徹,花岡健二郎,長野哲雄
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] Protein-L-isoaspartyl methyltransferase (PIMT)の新規活性検出法の開発
- Author(s)
  木村勇亮,小松徹,長野哲雄,花岡健二郎,浦野泰照
- Organizer
  日本薬学会第134年会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブと非変性電気泳動法を利用した疾患関連酵素の網羅的探索法の開発
- Author(s)
  小松徹、吉岡健太郎、花岡健二郎、長野哲雄、浦野泰照
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都府(京都市)京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] Discovering Enzymes with Desired Biochemical Activities with Use of Small Molecular Fluorescent Substrate Probes
- Author(s)
  Toru Komatsu, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano
- Organizer
  ICBS2014
- Place of Presentation
  アメリカ(サンフランシスコ)
- Year and Date
  2014-11-17 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] 有機小分子による細胞膜外フェノタイプ制御法の開発と応用
- Author(s)
  大沼裕樹,小松徹,花岡健二郎,長野哲雄,井上尊生
- Organizer
  日本ケミカルバイオロジー学会第8回年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いたホルミル化ペプチド代謝酵素の探索と機能評価
- Author(s)
  小松徹,川口充康,長野哲雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子蛍光プローブを用いた酸化損傷タンパク質代謝酵素の探索
- Author(s)
  吉岡健太郎,小松徹,長野哲雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  (ポスター発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 有機小分子による細胞膜外フェノタイプ制御法の開発と応用
- Author(s)
  大沼裕樹,小松徹,花岡健二郎,長野哲雄,井上尊生
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24655147
[Presentation] 酵素活性の網羅的解析に利用可能な蛍光プローブ群の開発と活性評価
- Author(s)
  小松徹、吉岡健太郎、小名木淳、花岡健二郎、浦野泰照
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山県(岡山市)岡山大学津島キャンパス
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-22000006
[Presentation] Diced electrophoresis gel assay for screening enzymes with specified activities
- Author(s)
  Toru Komatsu
- Organizer
  Sino-Japan Workshop on Chemical Biology
- Place of Presentation
  中国(北京)
- Year and Date
  2014-10-10 – 2014-10-13
- Data Source
  KAKENHI-PROJECT-22000006
[]
[]

1. HANAOKA Kenjiro (70451854)

# of Collaborated Projects: 2 results

# of Collaborated Products: 53 results
2. NAGANO Tetsuo (20111552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 50 results
3. HIRATA Yasunobu (70167609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. TERAI Takuya (00508145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
5. UENO Tasuku (60462660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
6. TAKAHASHI Masao (00447418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 土屋幸弘 (30455406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 水野忠快 (90736050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. TAKAHASHI Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. SAITO Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. HINO Rumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 鈴木穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 森宙史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 相良剛光

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 浦野泰照

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 神吉智丈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 神谷真子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 三國貴康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 中村匡良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 吉成晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 岩楯好昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 高柳俊夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 張翼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Komatsu Toru 小松 徹

KOMATSU Toru 小松 徹

Research Projects

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Co-Researchers

ケミカルプローブの全自動合成に基づく enzymomics 研究の高度化Principal Investigator

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Development of enzymomics platform for characterization of disease-related alterations of enzymatic activitiesPrincipal Investigator

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Development of chemical tools for multimodal imaging of supersulfides and manipulation of their biosynthesis

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Development of synthetic biological tools to modify metabolic fates of cellsPrincipal Investigator

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Establishment of enzymomics platform for discovery of disease-related protein functionsPrincipal Investigator

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Development of on-organelle protein trapping method to study the meanings of transient organelle localization of tumor-associated proteinsPrincipal Investigator

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Development of coupled assay-based fluorescent probes to monitor post-translational modification reactions in live cellsPrincipal Investigator

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Development of chemical biological tools to monitor and control pathologically important methyltransferase activitesPrincipal Investigator

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Development of synthetic biological tools for modulating metabolic fates of cellsPrincipal Investigator

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Development of chromophore-assisted laser scarring method for characterization of drug target proteinsPrincipal Investigator

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Development of synthetic photo-functional molecules for medical applications

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[Book] 疾患と関わる酵素の働きを夾雑環境下で「視る」2023

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[Book] 茶カテキンによるエピジェネティック制御因子への関与2022

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Komatsu Toru 小松徹

KOMATSU Toru 小松徹

[Book] 酵素のはたらきを見て疾患を知る～Activity-based diagnosticsの最新動向～2021

[Book] 酵素のはたらきを見て疾患を知る～Activity-based diagnosticsの最新動向～2021