Yokota Naoto 横田直人

… Alternative Names

YOKOTA Naoto 横田直人

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Researcher Number	40610564
Other IDs
Affiliation (Current)	2025: 東京都立大学, 理学研究科, 助教
Affiliation (based on the past Project Information) *help	2011 – 2016: 首都大学東京, 理工学研究科, 助教 2013: 首都大学東京, 大学院・理工学研究科, 助教 2012: 首都大学東京, 大学院理工学研究科, 助教
Review Section/Research Field	Principal Investigator Functional biochemistry Except Principal Investigator Biological Sciences / Cell biology / Functional biochemistry
Keywords	Principal Investigator 凝集体 / 不良タンパク質代謝 / 核内凝集体 / 不良タンパク質 / BAG6 Except Principal Investigator プロテアソーム / ユビキチン / アグリソーム / タンパク質品質管理 / 分子シャペロン … More / 細胞内タンパク質分解 / タンパク質の品質管理 / BAG6 / UBA / 凝集体形成 / ユビキチン識別タンパク質 / テイルアンカータンパク質 / UBQLN / 構造解析 / TRC複合体 / ユビキチンコード / 蛋白質の品質管理 / ユビキチン結合蛋白質 / ユビキチン認識タンパク質 / ポリユビキチン認識 / UBAドメイン / UBQLN4 / 膜タンパク質 / 蛋白質品質管理 / ヘッジホッグ / GLI / Patched1 / 抗原提示 / タンパク質分解 / Scythe / BAT3 / 新合成ポリペプチド Less

Roles of BAG6 complex in nuclear protein quality contorolPrincipal Investigator
- Principal Investigator
  
  YOKOTA Naoto
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan University
Function of ubiquitin-associated domain proteins for decoding polyubiquitin signaling.
- Principal Investigator
  
  Hiroyuki Kawahara
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan University
Functional significance of BAG6 in quality control of nascent polypeptides
- Principal Investigator
  
  KAWAHARA Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan University
Novel signaling pathway in Patched1.
- Principal Investigator
  
  KAWAHARA Hiroyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan University

All 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition.2016
- Author(s)
  Tanaka, H., Takahashi, T., Xie, Y., Minami, R., Yanagi, Y., Hayashishita, M., Suzuki, R., Yokota, N., Shimada, M., Mizushima, T., Kuwabara, N., Kato, R., Kawahara, H.
- Journal Title
  
  FEBS J.
  
  Volume: 283 Issue: 4 Pages: 662-677
- DOI
  10.1111/febs.13618
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-14J05957, KAKENHI-PROJECT-26840029, KAKENHI-PLANNED-24112007, KAKENHI-PROJECT-16K14699
[Journal Article] Structure of a BAG6 (Bcl-2-associated Athanogene 6)-Ubl4a (Ubiquitin-like Protein 4a) Complex Reveals a Novel Binding Interface That Functions in Tail-anchored Protein Biogenesis.2015
- Author(s)
  Kuwabara N, Minami R, Yokota N, Matsumoto H, Senda T, Kawahara H, Kato R.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 15 Pages: 9387-9398
- DOI
  10.1074/jbc.m114.631804
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22121005, KAKENHI-PLANNED-24112007, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-25840038, KAKENHI-PROJECT-26840029
[Journal Article] Emerging roles in quality control for nascent polypeptides2013
- Author(s)
  Kawahara, H., Minami, R. and Yokota, N.
- Journal Title
  
  J. Biochem
  
  Volume: 153 Pages: 147-160
- URL
  http://jb.oxfordjournals.org/content/153/2/147.full
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23657135
[Journal Article] BAG6/BAT3 : Emerging roles in quality control for nascent polypeptides2013
- Author(s)
  Kawahara, H., Minami, R. and Yokota, N
- Journal Title
  
  J. Biochem
  
  Volume: 153 Issue: 2 Pages: 147-160
- DOI
  10.1093/jb/mvs149
- NAID
  40019566398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370063, KAKENHI-PROJECT-23657135, KAKENHI-PLANNED-24112007
[Presentation] Functional analysis of BAG6 and Ubl4a in Drosophila melanogaster.2015
- Author(s)
  atanabe, A., Yokota, N., Takeo, S., Aigaki, T., and Kawahara, H.
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会合同年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-24112007
[Presentation] RNA-binding protein ZFP36L2 is controlled during the cell cycle2014
- Author(s)
  Aya Noguchi, Naoto Yokota and Hiroyuki Kawahara
- Organizer
  International Meeting for New Aspects of the Ubiquitin Research
- Place of Presentation
  International Institute for Advanced Studies
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PLANNED-24112007
[Presentation] UBQLN4によるタンパク質品質管理機構2013
- Author(s)
  鈴木理滋, 福田有里, 横田直人, 川原裕之
- Organizer
  第８６回日本生化学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-24112007
[Presentation] 新規BAG6複合体構成因子の同定と解析Analysis of novel BAG6 interacting proteins2013
- Author(s)
  林下瑞希, 横田直人, 川原裕之
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] UBQLN4による新合成タンパク質の品質管理2013
- Author(s)
  鈴木理滋, 横田直人, 川原裕之
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」第1回領域班会議
- Place of Presentation
  淡路夢舞台
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 新規BAG6複合体構成因子の同定と解析2013
- Author(s)
  林下瑞希, 横田直人, 川原裕之
- Organizer
  第８６回日本生化学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-24112007
[Presentation] 新合成ポリペプチドの品質管理を担うBAG6複合体-その構造解明に向けて-2013
- Author(s)
  川原裕之, 南亮介, 横田直人
- Organizer
  物構研談話会
- Place of Presentation
  加速器研究機構(筑波)構造生物学研究センター
- Year and Date
  2013-01-07
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] Tis11BとTis11Dの細胞周期依存的なリン酸化と分解制御2013
- Author(s)
  野口あや, 川原裕之, 横田直人
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」第1回領域班会議
- Place of Presentation
  淡路夢舞台
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] UBQLN4によるタンパク質品質管理機構The function of UBQLN4 in protein quality control2013
- Author(s)
  鈴木理滋, 福田有里, 横田直人, 川原裕之
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 12回膜貫通タンパク質Patched1のアッセンブリと品質管理メカニズム2013
- Author(s)
  高橋俊樹, 横田直人, 川原裕之
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」第1回領域班会議
- Place of Presentation
  淡路夢舞台
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] Roles of mamalian GET components in BAG6-mediated protein control2013
- Author(s)
  Naoto Yokota, Hiroyuki Kawahara
- Organizer
  The 35th Naito Conference: The Ubiquitin-Proteasome system
- Place of Presentation
  シャトレーゼガトーキングダム（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-25840038
[Presentation] UBQLN4によるタンパク質品質管理機構2013
- Author(s)
  鈴木理滋, 福田有里, 横田直人, 川原裕之
- Organizer
  第８６回日本生化学会年会ポスター
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] Tis11B/Dのリン酸化依存的な局在変化と分解制御機構The localization and degradation of Tis11B/D are dependent on their phosphorylation state2013
- Author(s)
  野口あや, 川原裕之, 横田直人
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] BAG6と相互作用する新奇タンパク質の探索-質量分析からのアプローチ2013
- Author(s)
  林下瑞希, 横田直人, 川原裕之
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」第1回領域班会議
- Place of Presentation
  淡路夢舞台
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 哺乳類Getタンパク質群の機能から探る, BAG6の細胞恒常性維持機構」科研費新学術領域研究「ユビキチンネオバイオロジー2013
- Author(s)
  横田直人, 川原裕之
- Organizer
  第1回領域班会議
- Place of Presentation
  淡路夢舞台
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 12回膜貫通タンパク質Patched1 のアッセンブリと品質管理メカニズム2013
- Author(s)
  高橋俊樹、横田直人、川原裕之
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」第1回領域班会議
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-23657135
[Presentation] 免疫応答におけるBAG6タンパク質の意義2012
- Author(s)
  池尻昂史, 横田直人, 川原裕之
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 新合成タンパク質の品質管理におけるBAG6結合タンパク質UBQLN4の役割2012
- Author(s)
  鈴木理滋, 横田直人, 川原裕之
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 易凝集性タンパク質の品質管理におけるBAG6複合体の役割BAG6 is essential for selective elimination of aggregatin-prone proteins.2012
- Author(s)
  川原裕之, 南亮介, 横田直人
- Organizer
  第12回日本蛋白質科学会年会ワークショップ「invivo蛋白質科学 : 構造形成と分解」
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 細胞周期制御におけるヒトTis11b, Tis11dの機能解析2012
- Author(s)
  野口あや, 川原裕之, 横田直人
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] BAG6新奇スプライシングバリアントの同定と解析2012
- Author(s)
  林下瑞希, 横田直人, 川原裕之
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] ユビキチン識別タンパク質複合体による新合成ポリペプチド鎖の品質管理2012
- Author(s)
  川原裕之, 横田直人
- Organizer
  新学術領域研究「ユビキチンネオバイオロジー : 拡大するタンパク質制御システム」Kick-offシンポジウム
- Place of Presentation
  京大医学部
- Year and Date
  2012-09-26
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] 細胞内凝集体の形成制御におけるBAG6/GDX複合体の機能2011
- Author(s)
  松本裕文, 南亮介, 横田直人, 川原裕之
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23370063
[Presentation] ヘッジホッグレセプターPatched1の細胞質ドメインに結合する新規タンパク質の同定と機能解析
- Author(s)
  玉木悠介，出水俊輔，賀川裕貴，横田直人，延優子，田岡万悟，礒辺俊明，川原裕之
- Organizer
  第３４回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23657135
[Presentation] Post-mitotic degradation of ZFP36L1 and ZFP36L2 is under control of C-terminal phosphorylation.
- Author(s)
  Aya Noguchi, Naoto Yokota, Hiroyuki Kawahara
- Organizer
  Cold Spring Harbor Meeting 2014, The Cell Cycle
- Place of Presentation
  Cold Spring Harbor laboratory
- Year and Date
  2014-05-13 – 2014-05-17
- Data Source
  KAKENHI-PLANNED-24112007
[Presentation] タンパク質品質管理システムにおけるTRC35/BAG6相互作用の意義
- Author(s)
  田中花実，横田直人，川原裕之
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25840038

1. KAWAHARA Hiroyuki (70291151)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
2. KUWABARA Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 千田俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 水島恒裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 加藤龍一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yokota Naoto 横田 直人

YOKOTA Naoto 横田 直人

Research Projects

Research Products

Co-Researchers

Roles of BAG6 complex in nuclear protein quality contorolPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of ubiquitin-associated domain proteins for decoding polyubiquitin signaling.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional significance of BAG6 in quality control of nascent polypeptides

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel signaling pathway in Patched1.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure of a BAG6 (Bcl-2-associated Athanogene 6)-Ubl4a (Ubiquitin-like Protein 4a) Complex Reveals a Novel Binding Interface That Functions in Tail-anchored Protein Biogenesis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emerging roles in quality control for nascent polypeptides2013

Author(s)

Journal Title

URL

Data Source

[Journal Article] BAG6/BAT3 : Emerging roles in quality control for nascent polypeptides2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Functional analysis of BAG6 and Ubl4a in Drosophila melanogaster.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] RNA-binding protein ZFP36L2 is controlled during the cell cycle2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] UBQLN4によるタンパク質品質管理機構2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規BAG6複合体構成因子の同定と解析Analysis of novel BAG6 interacting proteins2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] UBQLN4による新合成タンパク質の品質管理2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規BAG6複合体構成因子の同定と解析2013

Author(s)

Organizer

Yokota Naoto 横田直人

YOKOTA Naoto 横田直人