TAMURA Isao 田村功

Researcher Number	40610663
Other IDs
Affiliation (Current)	2025: 山口大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 山口大学, 医学部附属病院, 講師 2021 – 2023: 山口大学, 大学院医学系研究科, 助教 2016 – 2021: 山口大学, 医学部附属病院, 助教 2011 – 2014: 山口大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 脱落膜化 / 子宮内膜 / 子宮内膜間質細胞 / C/EBPβ / epigenetics / ヒストンアセチル化 / 絨毛栄養膜細胞 / 核内アクチン / H3K27ac / PGC-1α … More / PGC-1a / C/EBPb / ゲノム編集 / IGFBP-1 / エピジェネティクス … More Except Principal Investigator 着床不全 / 着床 / オルガノイド / 子宮内膜 / 脱落膜化 / iPS細胞 / 子宮内膜間質細胞 / 子宮内膜上皮細胞 / 子宮性不妊症 / 再生医療 / 不妊症 Less

Clarifying the ptathogenesis of decidualization failure using a novel human in vitro implantation modelPrincipal Investigator
- Principal Investigator
  
  田村功
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamaguchi University
独自の改良型子宮内膜オルガノイドを応用した着床機構および着床不全の病態の解明
- Principal Investigator
  
  杉野法広
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamaguchi University
Nuclear F-actin formation is an integral part of decidualization in human endometrial stromal cellsPrincipal Investigator
- Principal Investigator
  
  Tamura Isao
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamaguchi University
Establishment of endometrium organoids and application for regenerative medicine of endometrium
- Principal Investigator
  
  Sugino Norihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamaguchi University
Mechanisms by which C/EBPb inducues genome-wide H3K27ac during decidualization of human endometrial stromal cellsPrincipal Investigator
- Principal Investigator
  
  TAMURA Isao
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamaguchi University
The distal upstream region of insulin-like growth factor binding protein-1 enhances its expression in endometrial stromal cells during decidualizationPrincipal Investigator
- Principal Investigator
  
  TAMURA Isao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Induction of Mn-SOD by cAMP is associated with histone acetylation status aof the C/EBPb binding site of their promoters in human endometrial stromal cells.Principal Investigator
- Principal Investigator
  
  TAMURA Isao
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Involvement of epigenetic regulation in the expressions of decidualization related genesPrincipal Investigator
- Principal Investigator
  
  TAMURA Isao
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University

All 2024 2023 2022 2021 2020 2019 2018 2017 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Analysis of cell-cell interaction between mural granulosa cells and cumulus granulosa cells during ovulation using single‐cell <scp>RNA</scp> sequencing data of mouse ovary2024
- Author(s)
  Shirafuta Yuichiro、Tamura Isao、Shiroshita Amon、Fujimura Taishi、Maekawa Ryo、Taketani Toshiaki、Sugino Norihiro
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 23 Issue: 1
- DOI
  10.1002/rmb2.12564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15838, KAKENHI-PROJECT-23K27734
[Journal Article] Differential gene expression in decidualized human endometrial stromal cells induced by different stimuli.2024
- Author(s)
  Doi-Tanaka Y, Tamura I, Shiroshita A, Fujimura T, Shirafuta Y, Maekawa R, Taketani T, Sato S, Sugino N
- Journal Title
  
  Sci Rep
  
  Volume: 14 Issue: 1 Pages: 7726-7726
- DOI
  10.1038/s41598-024-58065-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27734
[Journal Article] Genome-wide analysis of histone modifications that underlie the dynamic changes in gene expression during decidualization in human endometrial stromal cells2023
- Author(s)
  Tamura Isao、Shiroshita Amon、Fujimura Taishi、Tanaka-Doi Yumiko、Shirafuta Yuichiro、Maekawa Ryo、Taketani Toshiaki、Sato Shun、Sugino Norihiro
- Journal Title
  
  Molecular Human Reproduction
  
  Volume: 29 Issue: 7
- DOI
  10.1093/molehr/gaad019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09495, KAKENHI-PROJECT-23K27734
[Journal Article] Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas2023
- Author(s)
  Maekawa Ryo、Ota Yoshiaki、Ota Ikuko、Mihara Yumiko、Takasaki Hitomi、Sato Shun、Tamura Isao、Shirafuta Yuichiro、Shinagawa Masahiro、Fujimura Taishi、Shiroshita Amon、Yoneda Toshihide、Kawamoto‐Jozaki Mai、Matsui Fuka、Taketani Toshiaki、Sugino Norihiro
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 22 Issue: 1
- DOI
  10.1002/rmb2.12548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09495, KAKENHI-PROJECT-23K27734
[Journal Article] Glucose and lipid metabolisms in human endometrial stromal cells during decidualization2023
- Author(s)
  Tamura Isao、Shiroshita Amon、Fujimura Taishi、Tanaka-Doi Yumiko、Shirafuta Yuichiro、Taketani Toshiaki、Sato Shun、Sugino Norihiro
- Journal Title
  
  Endocr J
  
  Volume: 70 Issue: 5 Pages: 465-472
- DOI
  10.1507/endocrj.EJ23-0099
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09495, KAKENHI-PROJECT-23K27734
[Journal Article] Effects of Melatonin on the Transcriptome of Human Granulosa Cells, Fertilization and Blastocyst Formation.2022
- Author(s)
  Isao Tamura, Hiroshi Tamura, Mai Kawamoto-Jozaki, Yuichiro Shirafuta, Taishi Fujimura, Yumiko Doi-Tanaka, Yumiko Mihara, Toshiaki Taketani, Norihiro Sugino
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 12 Pages: 6731-6731
- DOI
  10.3390/ijms23126731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09517, KAKENHI-PROJECT-20H03825
[Journal Article] Transcriptional coactivator PGC-1α contributes to decidualization by forming a histone-modifying complex with C/EBPβ and p3002022
- Author(s)
  Takagi Haruka、Tamura Isao、Fujimura Taishi、Doi-Tanaka Yumiko、Shirafuta Yuichiro、Mihara Yumiko、Maekawa Ryo、Taketani Toshiaki、Sato Shun、Tamura Hiroshi、Sugino Norihiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: in press Issue: 5 Pages: 101874-101874
- DOI
  10.1016/j.jbc.2022.101874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09495, KAKENHI-PROJECT-20H03825, KAKENHI-PROJECT-20K09645
[Journal Article] Transcription factor C/EBPβ induces genome-wide H3K27ac and upregulates gene expression during decidualization of human endometrial stromal cells2021
- Author(s)
  Tamura Isao、Maekawa Ryo、Jozaki Kosuke、Ohkawa Yasuyuki、Takagi Haruka、Doi-Tanaka Yumiko、Shirafuta Yuichiro、Mihara Yumiko、Taketani Toshiaki、Sato Shun、Tamura Hiroshi、Sugino Norihiro
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 520 Pages: 111085-111085
- DOI
  10.1016/j.mce.2020.111085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09645, KAKENHI-PROJECT-19K22688, KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-20H04846, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-20H03825, KAKENHI-PROJECT-18K09262, KAKENHI-PROJECT-18K09230, KAKENHI-PROJECT-19H03424
[Journal Article] The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium2021
- Author(s)
  Tamura Isao、Fujimura Taishi、Doi-Tanaka Yumiko、Takagi Haruka、Shirafuta Yuichiro、Kajimura Takuya、Mihara Yumiko、Maekawa Ryo、Taketani Toshiaki、Sato Shun、Tamura Hiroshi、Sugino Norihiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 297 Issue: 4 Pages: 101150-101150
- DOI
  10.1016/j.jbc.2021.101150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22688, KAKENHI-PROJECT-20H03825, KAKENHI-PROJECT-20K09645, KAKENHI-PROJECT-21K09495
[Journal Article] Integrated Analysis of Transcriptome and Histone Modifications in Granulosa Cells During Ovulation in Female Mice2021
- Author(s)
  Shirafuta Yuichiro、Tamura Isao、Ohkawa Yasuyuki、Maekawa Ryo、Doi-Tanaka Yumiko、Takagi Haruka、Mihara Yumiko、Shinagawa Masahiro、Taketani Toshiaki、Sato Shun、Tamura Hiroshi、Sugino Norihiro
- Journal Title
  
  Endocrinology
  
  Volume: 162 Issue: 9 Pages: 1-17
- DOI
  10.1210/endocr/bqab128
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22688, KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-20H04846, KAKENHI-PUBLICLY-21H00232, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-20H03825, KAKENHI-PROJECT-20K18191, KAKENHI-PROJECT-21K09495
[Journal Article] Relationship between follicular size and developmental capacity of oocytes under controlled ovarian hyperstimulation in assisted reproductive technologies2021
- Author(s)
  Tamura Isao、Kawamoto‐Jozaki Mai、Fujimura Taishi、Doi‐Tanaka Yumiko、Takagi Haruka、Shirafuta Yuichiro、Mihara Yumiko、Taketani Toshiaki、Tamura Hiroshi、Sugino Norihiro
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 20 Issue: 3 Pages: 299-304
- DOI
  10.1002/rmb2.12382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22688, KAKENHI-PROJECT-20H03825
[Journal Article] Long-term melatonin treatment attenuates body weight gain with aging in female mice2021
- Author(s)
  Tamura Isao、Tamura Hiroshi、Kawamoto-Jozaki Mai、Doi-Tanaka Yumiko、Takagi Haruka、Shirafuta Yuichiro、Mihara Yumiko、Maekawa Ryo、Taketani Toshiaki、Sato Shun、Sugino Norihiro
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 251 Issue: 1 Pages: 15-25
- DOI
  10.1530/joe-20-0462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22688, KAKENHI-PROJECT-20H03825, KAKENHI-PROJECT-21K09495
[Journal Article] Wilms tumor 1 regulates lipid accumulation in human endometrial stromal cells during decidualization2020
- Author(s)
  Tamura Isao、Takagi Haruka、Doi-Tanaka Yumiko、Shirafuta Yuichiro、Mihara Yumiko、Shinagawa Masahiro、Maekawa Ryo、Taketani Toshiaki、Sato Shun、Tamura Hiroshi、Sugino Norihiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: in press Issue: 14 Pages: 4673-4683
- DOI
  10.1074/jbc.ra120.012841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09262, KAKENHI-PROJECT-20K09645, KAKENHI-PROJECT-19K22688, KAKENHI-PROJECT-20H03825, KAKENHI-PROJECT-18K09230
[Journal Article] The distal upstream region of insulin-like growth factor-binding protein-1 enhances its expression in endometrial stromal cells during decidualization2018
- Author(s)
  Tamura I, Jozaki K, Sato S, Shirafuta Y, Shinagawa M, Maekawa R, Taketani T, Asada H, Tamura H, Sugino N.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 14 Pages: 5270-5280
- DOI
  10.1074/jbc.ra117.000234
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10720, KAKENHI-PROJECT-16K20191, KAKENHI-PROJECT-18K09262
[Journal Article] Importance ofC/EBPβbinding and histone acetylation status in the promoter regions for induction of IGFBP-1, PRL and Mn-SOD by cAMP in human endometrial stromalcell2014
- Author(s)
  Isao Tamura, Shun Sato, Maki Okada, Manabu Tanabe, Lifa Lee, Ryo Maekawa, Hiromi Asada, Yoshiaki Yamagata, Hiroshi Tamura, Norihiro Sugino
- Journal Title
  
  Endocrinology
  
  Volume: 155 Pages: 275-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861495
[Journal Article] Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the promoter region in human endometrial stromal cells2012
- Author(s)
  I.Tamura, Hiromi Asada.
- Journal Title
  
  Endocrinology
  
  Volume: 153(Endocrinology)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890140
[Journal Article] Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the promoter region in human endometrial stromal cells.2012
- Author(s)
  Isao Tamura
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 5612-5621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] Establishment of in vitro implantation model using newly developed endometrial organoid2024
- Author(s)
  Fujimura, T, Tamura I, Shinagawa M, Sugino N
- Organizer
  71th annual scientific meeting of Society for Reproductive Investigation
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] Nuclear F-actin formation regulates decidualization of human endometrial stromal cells2024
- Author(s)
  Tamura I, Fujimura T, Shinagawa M, Sugino N
- Organizer
  71th annual scientific meeting of Society for Reproductive Investigation
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] 子宮内膜上皮・間質複合オルガノイドを用いたin vitro 着床モデルの樹立2023
- Author(s)
  藤村大志、田村　功、米田稔秀、城下亜文、高崎ひとみ、白蓋雄一郎、竹谷俊明、佐藤　俊、杉野法広
- Organizer
  第68回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] 3次元子宮内膜様構造体を用いたin vitro 着床モデルの樹立2023
- Author(s)
  藤村大志、田村　功、米田稔秀、城下亜文、高崎ひとみ、白蓋雄一郎、佐藤　俊、杉野法広
- Organizer
  日本繁殖生物学会第116回大会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] Effects of melatonin on the transcriptome of human granulosa cells, fertilization and blastocyst formation2023
- Author(s)
  I.Tamura, H.Tamura, H.Takasaki, A.Shiroshita, T.Fujimura, Y.Shirafuta, Y.Mihara, T.Taketani, N.Sugino
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] Analysis of Cell-Cell Interaction Between Mural Granulosa Cells and Cumulus Granulosa Cells During Ovulation Using Single-Cell RNA Sequencing Data of Mouse Ovar2023
- Author(s)
  Shirafuta Y, Tamura I, Fujimura T, Sugino N
- Organizer
  56th Annual Meeting of the Society for the Study on Reproduction
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] Differential gene expression and cellular functions in decidualized human endometrial stromal cells induced by different stimuli.2023
- Author(s)
  Tamura I, Fujimura T, Shirafuta Y, Sugino N
- Organizer
  56th Annual Meeting of the Society for the Study on Reproduction
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] 脱落膜化に不可欠な糖取り込みを制御するGLUT1は転写因子C/EBPβとWT1により epigeneticに制御される2023
- Author(s)
  田村　功、高崎ひとみ、城下亜文、藤村大志、白蓋雄一郎、前川　亮、田村博史、杉野法広
- Organizer
  第96回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] 核内アクチンによるヒト子宮内膜間質細胞脱落膜化の調節機構の解明2023
- Author(s)
  田村　功、高崎ひとみ、城下亜文、藤村大志、白蓋雄一郎、竹谷俊明、杉野法広
- Organizer
  第68回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] 新規子宮内膜オルガノイドを用いたin vitro 着床モデルの確立2023
- Author(s)
  藤村大志、田村　功、米田稔秀、城下亜文、高崎ひとみ、佐藤　俊、杉野法広
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] 脱落膜化不全の病態解明にむけて：C/EBPβによる脱落膜化制御機構の解明2023
- Author(s)
  田村　功
- Organizer
  第41回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPbeta and WT1 during decidualization of human endometrial stromal cells.2023
- Author(s)
  Tamura I, Tamehisa T, Sugino N
- Organizer
  70th annual scientific meeting of Society for Reproductive Investigation
- Data Source
  KAKENHI-PROJECT-23K27734
[Presentation] The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPbeta and WT1 during decidualization of human endometrial stromal cells.2023
- Author(s)
  Tamura I, Tamehisa T, Sugino N
- Organizer
  70th annual scientific meeting of Society for Reproductive Investigation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] Transcriptional coactivator PGC1a contributes to decidualization by forming a transcription complex with C/EBPb / p300 and inducing epigenomic changes2020
- Author(s)
  Haruka Takagi, Isao Tamura, Natsuko Shimizu, Yumiko Tanaka, Yuichiro Shirafuta, Yumiko Mihara, Masahiro Shinagawa, Ryo Maekawa, Toshiaki Taketani, Hiroshi Tamura, Norihiro Sugino
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] ヒト子宮内膜間質細胞の脱落膜化における転写因子C/EBPβを介したヒストン修飾による遺伝子発現制御機構2020
- Author(s)
  田村　功、前川　亮、田中　結美子、高木　遥香、白蓋雄一郎、三原由実子、竹谷俊明、田村博史、杉野法広
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] 転写共役因子PGC-1aはC/EBPb、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、藤村大志、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第65回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] C/EBPb a transcription factor, genome-widely regulates gene expression through H3K27ac modifications during decidualization of human endometrial stromal cells (ESCs)2020
- Author(s)
  Isao Tamura, Ryo Maekawa, Haruka Takagi, Natsuko Shimizu, Yumiko Tanaka-Doi, Yuichiro Shirafuta, Yumiko Mihara, Toshiaki Taketani, Hiroshi Tamura, Norihiro Sugino
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] 転写因子Wilms tumor 1 (WT1)は子宮内膜間質細胞脱落膜化における脂質蓄積を制御する2020
- Author(s)
  田村　功、高木遥香、田中結美子、白蓋雄一郎、三原由美子、前川　亮、竹谷俊明、佐藤　俊、田村博史、杉野法広
- Organizer
  第25回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] 転写共役因子PGC1αはC/EBPBβ、p300 と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する。2020
- Author(s)
  高木遥香、田村功、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、品川征大、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第24回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] 転写共役因子PGC-1αはC/EBPβ、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、品川征大、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] Transcriptional coactivator PGC1a contributes to decidualization by forming a transcription complex with C/EBPb / p300 and inducing epigenomic changes2020
- Author(s)
  Haruka Takagi, Isao Tamura, Natsuko Shimizu, Yumiko Tanaka, Yuichiro Shirafuta, Yumiko Mihara, Masahiro Shinagawa, Ryo Maekawa, Toshiaki Taketani, Hiroshi Tamura, Norihiro Sugino.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] 転写因子Wilms tumor 1 (WT1)は子宮内膜間質細胞脱落膜化における脂質蓄積を制御する2020
- Author(s)
  田村　功、高木遥香、田中結美子、白蓋雄一郎、三原由美子、前川　亮、竹谷俊明、佐藤　俊、田村博史、杉野法広
- Organizer
  第25回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] 転写共役因子PGC-1aはC/EBPb、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、藤村大志、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第113回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] 転写共役因子PGC-1αはC/EBPβ、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村　功、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、品川征大、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] 転写共役因子PGC-1aはC/EBPb、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、藤村大志、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第113回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] 転写共役因子PGC-1αはC/EBPβ、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、藤村大志、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第38回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20H03825
[Presentation] C/EBPb a transcription factor, genome-widely regulates gene expression through H3K27ac modifications during decidualization of human endometrial stromal cells (ESCs)2020
- Author(s)
  Isao Tamura, Ryo Maekawa, Haruka Takagi, Natsuko Shimizu, Yumiko Tanaka-Doi, Yuichiro Shirafuta, Yumiko Mihara, Toshiaki Taketani, Hiroshi Tamura, Norihiro Sugino
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] 転写共役因子PGC-1aはC/EBPb、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、藤村大志、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第65回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] ヒト子宮内膜間質細胞の脱落膜化における転写因子C/EBPβを介したヒストン修飾による遺伝子発現制御機構2020
- Author(s)
  田村　功、前川　亮、田中　結美子、高木　遥香、白蓋雄一郎、三原由実子、竹谷俊明、田村博史、杉野法広
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] 転写共役因子PGC-1αはC/EBPβ、p300と転写複合体を形成しエピゲノム変化を誘導することで脱落膜化に貢献する2020
- Author(s)
  高木遥香、田村功、藤村大志、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第38回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] ヒト子宮内膜間質細胞の脱落膜化過程におけるPGC1αの機能とその調節機構2019
- Author(s)
  高木遥香、田村功、田中結美子、白蓋雄一郎、三原由実子、品川征大、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] ヒト子宮内膜間質細胞の脱落膜化過程におけるPGC1αの機能とその調節機構2019
- Author(s)
  高木遥香、田村功、清水奈都子、田中結美子、白蓋雄一郎、三原由実子、品川征大、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] The role and regulation of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) in decidualization of human endometrial stromal cells.2019
- Author(s)
  Haruka Takagi, Isao Tamura, Yuichiro Shirafuta, Ryo Maekawa, Hiroshi Tamura, Norihiro Sugino.
- Organizer
  The 52th SSR anual meeting
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] ヒト子宮内膜間質細胞の脱落膜化過程におけるPGC1Aの機能とその調節機構2018
- Author(s)
  高木遥香、田村功、白蓋雄一郎、三原由実子、品川征大、前川亮、竹谷俊明、田村博史、杉野法広
- Organizer
  第111回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] Genome-wide epigenome analysis and genome editing identified a novel enhancer region for IGF binding protein-1 (IGFBP-1) expression in human endometrial stromal cells undergoing decidualization2018
- Author(s)
  Isao Tamura, Haruka Takagi, Yuichiro Shirafuta, Norihiro Sugino
- Organizer
  Society for the Study of Reproduction 2018 annual meeting
- Data Source
  KAKENHI-PROJECT-16K20191
[Presentation] The role and regulation of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1Aa) in decidualization of human endometrial stromal cells.2018
- Author(s)
  Haruka Takagi, Isao Tamura, Yuichiro Shirafuta, Norihiro Sugino.
- Organizer
  SSR 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09230
[Presentation] エピゲノムから見えてきた子宮内膜脱落膜化の分子メカニズム2017
- Author(s)
  田村　功
- Organizer
  第62回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K20191
[Presentation] ヒト子宮内膜間質細胞 (ESC) における脱落膜化関連遺伝子発現のエピジェネティクス調節2013
- Author(s)
  田村　功
- Organizer
  第31回日本受精着床学会総会・学術講演会
- Place of Presentation
  別府市（別府国際コンベンションセンター）
- Invited
- Data Source
  KAKENHI-PROJECT-25861495
[Presentation] Induction of IGFBP-1, PRL and Mn-SOD by cAMP is associated with histone acetylation status of the C/EBPβ binding site of their promoters in human endometrial stromal cells2013
- Author(s)
  Isao Tamura, Maki Okada, Manabu Tanabe, Lifa Lee, Norihiro Sugino
- Organizer
  Annual meeting of the society for the study on reproduction
- Place of Presentation
  モントリオール/カナダ
- Data Source
  KAKENHI-PROJECT-25861495
[Presentation] 子宮内膜間質細胞（ESC）の脱落膜化によって上昇する遺伝子発現におけるC/EBPβを介したエピジェネティクス調節機構2013
- Author(s)
  田村　功、岡田真紀、李　理華、前川　亮、浅田裕美、佐藤　俊、山縣芳明、田村博史、杉野法広
- Organizer
  日本エピジェネティクス研究会第７回年会
- Place of Presentation
  奈良市(奈良県新公会堂）
- Data Source
  KAKENHI-PROJECT-25861495
[Presentation] ヒト子宮内膜間質細胞（ESC）の脱落膜化によって誘導されるmanganese superoxide dismutase (Mn-SOD) 遺伝子発現に関与する新たな転写調節経路2013
- Author(s)
  田村　功、田辺　学、李　理華、前川　亮、浅田裕美、山縣芳明、田村博史、杉野法広
- Organizer
  日本産婦人科学会学術講演会
- Place of Presentation
  札幌市（ロイトン札幌）
- Data Source
  KAKENHI-PROJECT-25861495
[Presentation] ヒト子宮内膜間質細胞（ESC）の脱落膜化によって誘導されるmanganese superoxide dismutase (Mn-SOD) 遺伝子発現に関与する新たな転写調節経路2013
- Author(s)
  田村　功、田辺　学、李　理華、前川　亮、浅田裕美、山縣芳明、田村博史、杉野法広
- Organizer
  日本内分泌学会
- Place of Presentation
  仙台市(仙台国際センター）
- Data Source
  KAKENHI-PROJECT-25861495
[Presentation] ヒト子宮内膜間質細胞 (ESC) の脱落膜化によって誘導されるIGFBP-1、PRL遺伝子発現におけるepigenetic調節機構の関与2012
- Author(s)
  田村功
- Organizer
  第6回日本エピジェネティクス研究会
- Place of Presentation
  東京学術総合センター
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the promoter region in human endometrial stromal cells.2012
- Author(s)
  Isao Tamura
- Organizer
  IFPA2012 Hiroshima meeting
- Place of Presentation
  広島広島国際会議場
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] ヒト子宮内膜間質細胞 (ESC) の脱落膜化によって誘導されるIGFBP-1、PRL遺伝子発現におけるepigenetic調節機構の関与2012
- Author(s)
  田村　功
- Organizer
  第6回日本エピジェネティクス研究会
- Place of Presentation
  学術総合センター（東京）
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the promoter region in human endometrial stromal cells2012
- Author(s)
  Isao Tamura
- Organizer
  IFPA 2012 Hiroshima Meeting
- Place of Presentation
  広島国際会議場（広島）
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] ヒト子宮内膜間質細胞 (ESC) の脱落膜化によって誘導されるIGFBP-1、PRL遺伝子発現におけるepigenetic調節機構の関与2012
- Author(s)
  田村功
- Organizer
  第30回日本受精着床学会総会.
- Place of Presentation
  大阪大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] ヒト子宮内膜間質細胞 (ESC) の脱落膜化によって誘導されるIGFBP-1、PRL遺伝子発現におけるepigenetic調節機構の関与2012
- Author(s)
  田村　功
- Organizer
  第30回日本受精着床学会総会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23890140
[Presentation] ヒト子宮内膜間質細胞(ESC)の脱落膜化によって誘導されるIGFBP-1、PRL遺伝子発現におけるepigenetic調節機構の関与2011
- Author(s)
  田村功
- Organizer
  第63回日本産婦人科学会学術講演会
- Place of Presentation
  リーガロイヤルホテル、大阪
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23890140

1. Sugino Norihiro (10263782)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
2. 宮本圭 (40740684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 宮本達雄 (40452627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大黒多希子 (30767249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKETANI Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 白蓋雄一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 佐藤俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
8. 田村博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAMURA Isao 田村 功

Research Projects

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Co-Researchers

Clarifying the ptathogenesis of decidualization failure using a novel human in vitro implantation modelPrincipal Investigator

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独自の改良型子宮内膜オルガノイドを応用した着床機構および着床不全の病態の解明

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Nuclear F-actin formation is an integral part of decidualization in human endometrial stromal cellsPrincipal Investigator

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Establishment of endometrium organoids and application for regenerative medicine of endometrium

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Mechanisms by which C/EBPb inducues genome-wide H3K27ac during decidualization of human endometrial stromal cellsPrincipal Investigator

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The distal upstream region of insulin-like growth factor binding protein-1 enhances its expression in endometrial stromal cells during decidualizationPrincipal Investigator

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Induction of Mn-SOD by cAMP is associated with histone acetylation status aof the C/EBPb binding site of their promoters in human endometrial stromal cells.Principal Investigator

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Involvement of epigenetic regulation in the expressions of decidualization related genesPrincipal Investigator

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[Journal Article] Analysis of cell-cell interaction between mural granulosa cells and cumulus granulosa cells during ovulation using single‐cell <scp>RNA</scp> sequencing data of mouse ovary2024

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[Journal Article] Differential gene expression in decidualized human endometrial stromal cells induced by different stimuli.2024

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[Journal Article] Genome-wide analysis of histone modifications that underlie the dynamic changes in gene expression during decidualization in human endometrial stromal cells2023

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[Journal Article] Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas2023

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[Journal Article] Glucose and lipid metabolisms in human endometrial stromal cells during decidualization2023

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[Journal Article] Effects of Melatonin on the Transcriptome of Human Granulosa Cells, Fertilization and Blastocyst Formation.2022

TAMURA Isao 田村功