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Umemura Yasuhiro  梅村 康浩

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UMEMURA Yasuhiro  梅村 康浩

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Researcher Number 40612734
Other IDs
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Affiliation (based on the past Project Information) *help 2024: 京都府立医科大学, 医学(系)研究科(研究院), 講師
2020 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 講師
2012 – 2019: 京都府立医科大学, 医学(系)研究科(研究院), 助教
2011 – 2012: 京都府立医科大学, 医学研究科, 助教
Review Section/Research Field
Principal Investigator
Environmental physiology(including physical medicine and nutritional physiology) / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 44020:Developmental biology-related / Complex Systems Disease Theory / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords
Principal Investigator
体内時計 / がん / 概日時計 / 細胞分化 / 概日リズム / 個体発生 / 体節時計 / 免疫学 / 発現制御 / 脳神経疾患 … More / 生理学 / 炎症 / 遺伝子 / 癌 / 発生・分化 / ES細胞 / ES 細胞 Less
  • Research Projects

    (6 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (4 People)
  •  Maternal-fetal entrainment mechanism of mammalian circadian rhythmsPrincipal Investigator

    • Principal Investigator
      梅村 康浩
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigation of the inhibitory mechanisms for circadian clock ossillation during early development of mammalsPrincipal Investigator

    • Principal Investigator
      Umemura Yasuhiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigation of the relationship between circadian clock disorders and inflammationPrincipal Investigator

    • Principal Investigator
      Yasuhiro Umemura
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Complex Systems Disease Theory
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigation of the gene network regulating the development of circadian clock in human cancer cell linesPrincipal Investigator

    • Principal Investigator
      Umemura Yasuhiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Circadian rhythm disruption in human cancersPrincipal Investigator

    • Principal Investigator
      Yasuhiro Umemura
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Disruption of circadian rhythm in malignant cancer cellsPrincipal Investigator

    • Principal Investigator
      UMEMURA Yasuhiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2021 2020 2019 2017 2015 2014 2013 2012 Other

All Journal Article Presentation Book

  • [Book] 細胞工学 2015年3月号2015

    • Author(s)
      梅村康浩, 八木田和弘
    • Total Pages
      2
    • Publisher
      株式会社 学研メディカル秀潤社
    • Data Source
      KAKENHI-PROJECT-25860179
  • [Journal Article] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021

    • Author(s)
      Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Watanabe Hitomi、Kondoh Gen、Kageyama Ryoichiro、Yagita Kazuhiro
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 1

    • DOI

      10.1073/pnas.2114083119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06679, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-21H02664, KAKENHI-PROJECT-19K06770, KAKENHI-ORGANIZER-21H05129
  • [Journal Article] Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice2020

    • Author(s)
      Inokawa Hitoshi, Umemura Yasuhiro, Shimba Akihiro, Kawakami Eiryo, Koike Nobuya, Tsuchiya Yoshiki, Ohashi Munehiro, Minami Yoichi, Cui Guangwei, Asahi Takuma, Ono Ryutaro, Sasawaki Yuh, Konishi Eiichi, Yoo Seung-Hee, Chen Zheng, Teramukai Satoshi, Ikuta Koichi, Yagita Kazuhiro
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 2569-2569

    • DOI

      10.1038/s41598-020-59541-y

    • NAID

      120006799241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-17K11021, KAKENHI-PROJECT-17KT0129, KAKENHI-PROJECT-18K15184
  • [Journal Article] Development of the Circadian Core Machinery in Mammals2020

    • Author(s)
      Umemura Yasuhiro, Yagita Kazuhiro
    • Journal Title

      Journal of Molecular Biology

      Volume: - Issue: 12 Pages: 3611-3617

    • DOI

      10.1016/j.jmb.2019.11.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-19K06679
  • [Journal Article] Circadian clock and cancer: From a viewpoint of cellular differentiation2020

    • Author(s)
      Tsuchiya Yoshiki, Umemura Yasuhiro, Yagita Kazuhiro
    • Journal Title

      International Journal of Urology

      Volume: - Issue: 6 Pages: 518-524

    • DOI

      10.1111/iju.14231

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-19K06679, KAKENHI-PROJECT-18K06338
  • [Journal Article] Human Circadian Molecular Oscillation Development Using Induced Pluripotent Stem Cells.2019

    • Author(s)
      Umemura Y, Maki I, Tsuchiya Y, Koike N, Yagita K
    • Journal Title

      J Biol Rhythms

      Volume: 34 Issue: 5 Pages: 525-532

    • DOI

      10.1177/0748730419865436

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06679, KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600
  • [Journal Article] REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output2019

    • Author(s)
      Ikeda Ryosuke、Tsuchiya Yoshiki、Koike Nobuya、Umemura Yasuhiro、Inokawa Hitoshi、Ono Ryutaro、Inoue Maho、Sasawaki Yuh、Grieten Tess、Okubo Naoki、Ikoma Kazuya、Fujiwara Hiroyoshi、Kubo Toshikazu、Yagita Kazuhiro
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 10171-10171

    • DOI

      10.1038/s41598-019-46656-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06338, KAKENHI-PROJECT-18K09040, KAKENHI-PROJECT-19K06679, KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18K16629, KAKENHI-PROJECT-18H02600
  • [Journal Article] Involvement of posttranscriptional regulation ofClockin the emergence of circadian clock oscillation during mouse development2017

    • Author(s)
      Umemura Yasuhiro、Koike Nobuya、Ohashi Munehiro、Tsuchiya Yoshiki、Meng Qing Jun、Minami Yoichi、Hara Masayuki、Hisatomi Moe、Yagita Kazuhiro
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 114 Issue: 36

    • DOI

      10.1073/pnas.1703170114

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-15H04683
  • [Journal Article] Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors2017

    • Author(s)
      Ohashi Munehiro、Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Inada Yutaka、Watanabe Hitomi、Tanaka Tomoko、Minami Yoichi、Ukimura Osamu、Miki Tsuneharu、Tajiri Tatsuro、Kondoh Gen、Yamada Yasuhiro、Yagita Kazuhiro
    • Journal Title

      Genes to Cells

      Volume: 23 Issue: 2 Pages: 60-69

    • DOI

      10.1111/gtc.12552

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
  • [Journal Article] Parathyroid hormone resets the cartilage circadian clock of the organ-cultured murine femur.2015

    • Author(s)
      Okubo N, Fujiwara H, Minami Y, Kunimoto T, Hosokawa T, Umemura Y, Inokawa H, Asada M, Oda R, Kubo T, Yagita K.
    • Journal Title

      Acta Orthopedica

      Volume: 13 Issue: 5 Pages: 1-5

    • DOI

      10.3109/17453674.2015.1029393

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-25670655, KAKENHI-PROJECT-25860179, KAKENHI-PROJECT-25861335, KAKENHI-PROJECT-26350697
  • [Journal Article] Cell and Tissue-autonomous development of the circadian clock in mouse embryos.2014

    • Author(s)
      Inada Y, Uchida H, Umemura Y, Nakamura W, Sakai T, Koike N, Yagita K.
    • Journal Title

      FEBS Lett

      Volume: 588 Issue: 3 Pages: 459-465

    • DOI

      10.1016/j.febslet.2013.12.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-24659109, KAKENHI-PROJECT-25860179
  • [Journal Article] Transcriptional Program of Kpna2 /Importin-α2 Regulates Cellular Differentiation-Coupled Circadian Clock Development in Mammalian Cells.2014

    • Author(s)
      Umemura Y, Koike N, Matsumoto T, Yoo S-H, Zhen C, Yasuhara N, Takahashi JS, Yagita K.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 111 Issue: 47 Pages: 5039-48

    • DOI

      10.1073/pnas.1419272111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390051, KAKENHI-PLANNED-25116008, KAKENHI-PROJECT-25860179
  • [Journal Article] Prolonged Bioluminescence Monitoring in Mouse ex vivo Bone Culture Revealed Persistent Circadian Rhythms in Articular Cartilages and Growth Plates.2013

    • Author(s)
      Okubo N, Minami Y, Fujiwara H, Umemura Y, Tsuchiya Y, Shirai Y, Oda R, Inokawa H, Kubo T, Yagita K*.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 11 Pages: e78306-e78306

    • DOI

      10.1371/journal.pone.0078306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-25670655, KAKENHI-PROJECT-25860179
  • [Presentation] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021

    • Author(s)
      梅村康浩, 小池宣也, 土谷佳樹, 渡邊仁美, 近藤玄, 影山龍一郎, 八木田和弘
    • Organizer
      第28回日本時間生物学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06679
  • [Presentation] 概日時計コア因子CLOCK/BMAL1による体節時計振動への干渉作用2021

    • Author(s)
      梅村康浩、小池宣也、土谷佳樹、渡邊仁美、近藤玄、影山龍一郎、八木田和弘
    • Organizer
      日本生理学会第113回近畿生理学談話会
    • Data Source
      KAKENHI-PROJECT-19K06679
  • [Presentation] ヒトiPS細胞を用いた概日時計の発生2019

    • Author(s)
      梅村康浩, 八木田和弘
    • Organizer
      第16回日本時間生物学会
    • Data Source
      KAKENHI-PROJECT-19K06679
  • [Presentation] ヒトiPS細胞を用いた概日時計の発生2019

    • Author(s)
      梅村康浩, 八木田和弘
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K06679
  • [Presentation] Involvement of post-transcriptional regulation of Clock in the emergence of circadian clock during cell differentiation.2017

    • Author(s)
      梅村康浩, 小池宣也, 土谷佳樹, 八木田和弘
    • Organizer
      第24回時間生物学会
    • Data Source
      KAKENHI-PROJECT-16K19008
  • [Presentation] Involvement of post-transcriptional regulation of Clock in the emergence of circadian clock during cell differentiation.2017

    • Author(s)
      梅村康浩, 小池宣也, 土谷佳樹, 八木田和弘
    • Organizer
      2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会・第90回日本生化学会大会)
    • Data Source
      KAKENHI-PROJECT-16K19008
  • [Presentation] 発生過程における概日時計の成立機構の解明2015

    • Author(s)
      八木田和弘, 小池宣也, 梅村康浩、大橋宗洋
    • Organizer
      新学術領域研究「ゲノム支援」
    • Place of Presentation
      京都
    • Year and Date
      2015-08-27
    • Data Source
      KAKENHI-PROJECT-25860179
  • [Presentation] 細胞分化センサーとしての生物時計2014

    • Author(s)
      梅村康浩
    • Organizer
      細胞センサーの分子機構・相互関連・ネットワーク研究会
    • Place of Presentation
      愛知、岡崎
    • Year and Date
      2014-12-04
    • Data Source
      KAKENHI-PROJECT-25860179
  • [Presentation] An in vitro ES cell-based clock recapitulation assay model identifies CK2alpha as an endogenous clock regulator.2013

    • Author(s)
      Umemura Y, Yoshida J, Wada M, Tsuchiya Y, Minami Y, Watanabe H, Kondoh G, Takeda J, Inokawa H, Horie K, Yagita K
    • Organizer
      第86回日本生化学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25860179
  • [Presentation] Effect of cellular reprogramming factors on circadian molecular oscillation in mammals.2012

    • Author(s)
      Yasuhiro Umemura
    • Organizer
      日本時間生物学会
    • Place of Presentation
      北海道大学学術交流会館 (北海道札幌市)
    • Data Source
      KAKENHI-PROJECT-23890180
  • [Presentation] Effect of cellular reprogramming factors on circadian molecular oscillation in mammals2012

    • Author(s)
      Yasuhiro Umemura
    • Organizer
      日本時間生物学会
    • Place of Presentation
      北海道大学学術交流会館 (北海道札幌市)
    • Data Source
      KAKENHI-PROJECT-23890180
  • [Presentation] Effect of cellular reprogramming factors on circadian molecular oscillation in mammals.2012

    • Author(s)
      Yasuhiro Umemura
    • Organizer
      Society of Research on Biological Rhythm
    • Place of Presentation
      Sandestin Golf and Beach Resort Destin (Florida, America)
    • Data Source
      KAKENHI-PROJECT-23890180
  • [Presentation] 細胞分化に伴う哺乳類概日時計の発生分子メカニズム

    • Author(s)
      梅村康浩, 小池宣也, 安原徳子, 八木田和弘
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-17 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25860179
  • 1.  八木田 和弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results
  • 2.  土谷 佳樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  井之川 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  渡邊 仁美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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