Umemura Yasuhiro 梅村康浩

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UMEMURA Yasuhiro 梅村康浩

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Researcher Number	40612734
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Affiliation (based on the past Project Information) *help	2024: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2020 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2012 – 2019: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2011 – 2012: 京都府立医科大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Environmental physiology(including physical medicine and nutritional physiology) / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 44020:Developmental biology-related / Complex Systems Disease Theory / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator 体内時計 / がん / 概日時計 / 細胞分化 / 概日リズム / 個体発生 / 体節時計 / 免疫学 / 発現制御 / 脳神経疾患 … More / 生理学 / 炎症 / 遺伝子 / 癌 / 発生・分化 / ES細胞 / ES 細胞 Less

Maternal-fetal entrainment mechanism of mammalian circadian rhythmsPrincipal Investigator
- Principal Investigator
  
  梅村康浩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of the inhibitory mechanisms for circadian clock ossillation during early development of mammalsPrincipal Investigator
- Principal Investigator
  
  Umemura Yasuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of the relationship between circadian clock disorders and inflammationPrincipal Investigator
- Principal Investigator
  
  Yasuhiro Umemura
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of the gene network regulating the development of circadian clock in human cancer cell linesPrincipal Investigator
- Principal Investigator
  
  Umemura Yasuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Kyoto Prefectural University of Medicine
Circadian rhythm disruption in human cancersPrincipal Investigator
- Principal Investigator
  
  Yasuhiro Umemura
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Kyoto Prefectural University of Medicine
Disruption of circadian rhythm in malignant cancer cellsPrincipal Investigator
- Principal Investigator
  
  UMEMURA Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto Prefectural University of Medicine

All 2021 2020 2019 2017 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 細胞工学 2015年３月号2015
- Author(s)
  梅村康浩, 八木田和弘
- Total Pages
  2
- Publisher
  株式会社　学研メディカル秀潤社
- Data Source
  KAKENHI-PROJECT-25860179
[Journal Article] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021
- Author(s)
  Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Watanabe Hitomi、Kondoh Gen、Kageyama Ryoichiro、Yagita Kazuhiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 1
- DOI
  10.1073/pnas.2114083119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06679, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-21H02664, KAKENHI-PROJECT-19K06770, KAKENHI-ORGANIZER-21H05129
[Journal Article] Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice2020
- Author(s)
  Inokawa Hitoshi, Umemura Yasuhiro, Shimba Akihiro, Kawakami Eiryo, Koike Nobuya, Tsuchiya Yoshiki, Ohashi Munehiro, Minami Yoichi, Cui Guangwei, Asahi Takuma, Ono Ryutaro, Sasawaki Yuh, Konishi Eiichi, Yoo Seung-Hee, Chen Zheng, Teramukai Satoshi, Ikuta Koichi, Yagita Kazuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 2569-2569
- DOI
  10.1038/s41598-020-59541-y
- NAID
  120006799241
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-17K11021, KAKENHI-PROJECT-17KT0129, KAKENHI-PROJECT-18K15184
[Journal Article] Development of the Circadian Core Machinery in Mammals2020
- Author(s)
  Umemura Yasuhiro, Yagita Kazuhiro
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: － Issue: 12 Pages: 3611-3617
- DOI
  10.1016/j.jmb.2019.11.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-19K06679
[Journal Article] Circadian clock and cancer: From a viewpoint of cellular differentiation2020
- Author(s)
  Tsuchiya Yoshiki, Umemura Yasuhiro, Yagita Kazuhiro
- Journal Title
  
  International Journal of Urology
  
  Volume: － Issue: 6 Pages: 518-524
- DOI
  10.1111/iju.14231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600, KAKENHI-PROJECT-19K06679, KAKENHI-PROJECT-18K06338
[Journal Article] Human Circadian Molecular Oscillation Development Using Induced Pluripotent Stem Cells.2019
- Author(s)
  Umemura Y, Maki I, Tsuchiya Y, Koike N, Yagita K
- Journal Title
  
  J Biol Rhythms
  
  Volume: 34 Issue: 5 Pages: 525-532
- DOI
  10.1177/0748730419865436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06679, KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600
[Journal Article] REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output2019
- Author(s)
  Ikeda Ryosuke、Tsuchiya Yoshiki、Koike Nobuya、Umemura Yasuhiro、Inokawa Hitoshi、Ono Ryutaro、Inoue Maho、Sasawaki Yuh、Grieten Tess、Okubo Naoki、Ikoma Kazuya、Fujiwara Hiroyoshi、Kubo Toshikazu、Yagita Kazuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10171-10171
- DOI
  10.1038/s41598-019-46656-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06338, KAKENHI-PROJECT-18K09040, KAKENHI-PROJECT-19K06679, KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18K16629, KAKENHI-PROJECT-18H02600
[Journal Article] Involvement of posttranscriptional regulation ofClockin the emergence of circadian clock oscillation during mouse development2017
- Author(s)
  Umemura Yasuhiro、Koike Nobuya、Ohashi Munehiro、Tsuchiya Yoshiki、Meng Qing Jun、Minami Yoichi、Hara Masayuki、Hisatomi Moe、Yagita Kazuhiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 36
- DOI
  10.1073/pnas.1703170114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-15H04683
[Journal Article] Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors2017
- Author(s)
  Ohashi Munehiro、Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Inada Yutaka、Watanabe Hitomi、Tanaka Tomoko、Minami Yoichi、Ukimura Osamu、Miki Tsuneharu、Tajiri Tatsuro、Kondoh Gen、Yamada Yasuhiro、Yagita Kazuhiro
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 2 Pages: 60-69
- DOI
  10.1111/gtc.12552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
[Journal Article] Parathyroid hormone resets the cartilage circadian clock of the organ-cultured murine femur.2015
- Author(s)
  Okubo N, Fujiwara H, Minami Y, Kunimoto T, Hosokawa T, Umemura Y, Inokawa H, Asada M, Oda R, Kubo T, Yagita K.
- Journal Title
  
  Acta Orthopedica
  
  Volume: 13 Issue: 5 Pages: 1-5
- DOI
  10.3109/17453674.2015.1029393
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-25670655, KAKENHI-PROJECT-25860179, KAKENHI-PROJECT-25861335, KAKENHI-PROJECT-26350697
[Journal Article] Cell and Tissue-autonomous development of the circadian clock in mouse embryos.2014
- Author(s)
  Inada Y, Uchida H, Umemura Y, Nakamura W, Sakai T, Koike N, Yagita K.
- Journal Title
  
  FEBS Lett
  
  Volume: 588 Issue: 3 Pages: 459-465
- DOI
  10.1016/j.febslet.2013.12.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-24659109, KAKENHI-PROJECT-25860179
[Journal Article] Transcriptional Program of Kpna2 /Importin-α2 Regulates Cellular Differentiation-Coupled Circadian Clock Development in Mammalian Cells.2014
- Author(s)
  Umemura Y, Koike N, Matsumoto T, Yoo S-H, Zhen C, Yasuhara N, Takahashi JS, Yagita K.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Issue: 47 Pages: 5039-48
- DOI
  10.1073/pnas.1419272111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390051, KAKENHI-PLANNED-25116008, KAKENHI-PROJECT-25860179
[Journal Article] Prolonged Bioluminescence Monitoring in Mouse ex vivo Bone Culture Revealed Persistent Circadian Rhythms in Articular Cartilages and Growth Plates.2013
- Author(s)
  Okubo N, Minami Y, Fujiwara H, Umemura Y, Tsuchiya Y, Shirai Y, Oda R, Inokawa H, Kubo T, Yagita K*.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e78306-e78306
- DOI
  10.1371/journal.pone.0078306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-25670655, KAKENHI-PROJECT-25860179
[Presentation] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021
- Author(s)
  梅村康浩, 小池宣也, 土谷佳樹, 渡邊仁美, 近藤玄, 影山龍一郎, 八木田和弘
- Organizer
  第28回日本時間生物学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06679
[Presentation] 概日時計コア因子CLOCK/BMAL1による体節時計振動への干渉作用2021
- Author(s)
  梅村康浩、小池宣也、土谷佳樹、渡邊仁美、近藤玄、影山龍一郎、八木田和弘
- Organizer
  日本生理学会第113回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-19K06679
[Presentation] ヒトiPS細胞を用いた概日時計の発生2019
- Author(s)
  梅村康浩, 八木田和弘
- Organizer
  第16回日本時間生物学会
- Data Source
  KAKENHI-PROJECT-19K06679
[Presentation] ヒトiPS細胞を用いた概日時計の発生2019
- Author(s)
  梅村康浩, 八木田和弘
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06679
[Presentation] Involvement of post-transcriptional regulation of Clock in the emergence of circadian clock during cell differentiation.2017
- Author(s)
  梅村康浩, 小池宣也, 土谷佳樹, 八木田和弘
- Organizer
  第２４回時間生物学会
- Data Source
  KAKENHI-PROJECT-16K19008
[Presentation] Involvement of post-transcriptional regulation of Clock in the emergence of circadian clock during cell differentiation.2017
- Author(s)
  梅村康浩, 小池宣也, 土谷佳樹, 八木田和弘
- Organizer
  2017年度生命科学系学会合同年次大会（第40回日本分子生物学会年会・第90回日本生化学会大会）
- Data Source
  KAKENHI-PROJECT-16K19008
[Presentation] 発生過程における概日時計の成立機構の解明2015
- Author(s)
  八木田和弘, 小池宣也, 梅村康浩、大橋宗洋
- Organizer
  新学術領域研究「ゲノム支援」
- Place of Presentation
  京都
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-25860179
[Presentation] 細胞分化センサーとしての生物時計2014
- Author(s)
  梅村康浩
- Organizer
  細胞センサーの分子機構・相互関連・ネットワーク研究会
- Place of Presentation
  愛知、岡崎
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-25860179
[Presentation] An in vitro ES cell-based clock recapitulation assay model identifies CK2alpha as an endogenous clock regulator.2013
- Author(s)
  Umemura Y, Yoshida J, Wada M, Tsuchiya Y, Minami Y, Watanabe H, Kondoh G, Takeda J, Inokawa H, Horie K, Yagita K
- Organizer
  第８６回日本生化学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860179
[Presentation] Effect of cellular reprogramming factors on circadian molecular oscillation in mammals.2012
- Author(s)
  Yasuhiro Umemura
- Organizer
  日本時間生物学会
- Place of Presentation
  北海道大学学術交流会館（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23890180
[Presentation] Effect of cellular reprogramming factors on circadian molecular oscillation in mammals2012
- Author(s)
  Yasuhiro Umemura
- Organizer
  日本時間生物学会
- Place of Presentation
  北海道大学学術交流会館 (北海道札幌市)
- Data Source
  KAKENHI-PROJECT-23890180
[Presentation] Effect of cellular reprogramming factors on circadian molecular oscillation in mammals.2012
- Author(s)
  Yasuhiro Umemura
- Organizer
  Society of Research on Biological Rhythm
- Place of Presentation
  Sandestin Golf and Beach Resort Destin (Florida, America)
- Data Source
  KAKENHI-PROJECT-23890180
[Presentation] 細胞分化に伴う哺乳類概日時計の発生分子メカニズム
- Author(s)
  梅村康浩, 小池宣也, 安原徳子, 八木田和弘
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-17 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25860179

1. 八木田和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
2. 土谷佳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 井之川仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 渡邊仁美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Umemura Yasuhiro 梅村 康浩

UMEMURA Yasuhiro 梅村 康浩

Research Projects

Research Products

Co-Researchers

Maternal-fetal entrainment mechanism of mammalian circadian rhythmsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the inhibitory mechanisms for circadian clock ossillation during early development of mammalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the relationship between circadian clock disorders and inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the gene network regulating the development of circadian clock in human cancer cell linesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Circadian rhythm disruption in human cancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Disruption of circadian rhythm in malignant cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞工学 2015年３月号2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Development of the Circadian Core Machinery in Mammals2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circadian clock and cancer: From a viewpoint of cellular differentiation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Circadian Molecular Oscillation Development Using Induced Pluripotent Stem Cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of posttranscriptional regulation ofClockin the emergence of circadian clock oscillation during mouse development2017

Author(s)

Journal Title

Umemura Yasuhiro 梅村康浩

UMEMURA Yasuhiro 梅村康浩