Osuga Takahiro 大須賀崇裕

Researcher Number	40619714
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2024: 札幌医科大学, 医学部, 助教 2014 – 2015: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics
Keywords	Principal Investigator 肝細胞癌 / 喫煙 / HIF-1α / 胃癌 Except Principal Investigator NK細胞 / CIML / ドラッグデリバリー / ドラッグデリバリーシステム / 膵癌 / TIM-3 … More / TIGIT / 肝細胞癌 / 固形癌 / CIML NK細胞 / 膵臓癌 / CAR / CAR-NK / 糖代謝特性 / 大腸癌 / 転移 / 大腸がん / 糖鎖 / バイオマーカー / liquid biopsy / digital PCR / フコース転移酵素 Less

Development of immunotherapy for hepatocellular carcinoma premedicated with a novel liposomal agent.Principal Investigator
- Principal Investigator
  
  大須賀崇裕
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
A novel treatment for hepatocellular carcinoma using CIML NK cells, TIM-3, and TIGIT inhibitors
- Principal Investigator
  
  宮西浩嗣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Novel strategies for the treatment of solid tumors with CAR and CIML NK cells
- Principal Investigator
  
  Miyanishi Koji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
Development of a Novel DDS with Tumor-Directed Anticancer Drugs for Pancreatic Cancer
- Principal Investigator
  
  Kato Junji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Developing a novel therapeutic strategy for advanced gastric cancer using the new genetic pathway of HIF-1 alpha.Principal Investigator
- Principal Investigator
  
  Osuga Takahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Development of a new treatment for colorectal cancer using the glucose metabolism characteristics.
- Principal Investigator
  
  Kato Junji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Sapporo Medical University
FUTを標的とした進行大腸癌に対する抗EMT療法の開発
- Principal Investigator
  
  瀧本理修
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Development of a novel pancreatic cancer rapid diagnostic method by the fucosyltransferases mRNA detection in peripheral blood
- Principal Investigator
  
  Kato Junji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University

All 2016 2015 2014

All Journal Article

[Journal Article] Relationship Between Increased Fucosylation and2016
- Author(s)
  Osuga T, Kato J, et al
- Journal Title
  
  J Natl Cancer Inst
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670386
[Journal Article] A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.2015
- Author(s)
  Sato Y, Ohnuma H, Hirakawa M, Takahashi M, Osuga T, Okagawa Y, Murase K, Takada K, Kawano Y, Iyama S, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Okita K, Mizuguchi T, Furuhata T, Hirata K, Kato J
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 75 Issue: 3 Pages: 587-597
- DOI
  10.1007/s00280-014-2672-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
[Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014
- Author(s)
  Tamura F, Sato Y, Hirakawa M, Yoshida M, Ono M, Osuga T, Okagawa Y, Uemura N, Arihara Y, Murase K, Kawano Y, Iyama S, Takada K, Hayashi T, Sato T, Miyanishi K, Kobune M, Takimoto R, Kato J.
- Journal Title
  
  Gastric Cancer
  
  Volume: 23 Issue: 1 Pages: 85-97
- DOI
  10.1007/s10120-014-0454-z
- NAID
  40020700032
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590921, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508

1. Kato Junji (20244345)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. Miyanishi Koji (60372819)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. 久保智洋 (00634669)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TAKIMONO Risyu (10336399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Okagawa Yutaka (50722386)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 濱口孝太 (50866613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 佐藤康史 (80343383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 早坂尚貴 (00792665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高田弘一 (90398321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 村瀬和幸 (90444918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中信悟 (60561024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 水口徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 佐藤昇志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 平田公一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 平川昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Osuga Takahiro 大須賀 崇裕

Research Projects

Research Products

Co-Researchers

Development of immunotherapy for hepatocellular carcinoma premedicated with a novel liposomal agent.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel treatment for hepatocellular carcinoma using CIML NK cells, TIM-3, and TIGIT inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel strategies for the treatment of solid tumors with CAR and CIML NK cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Novel DDS with Tumor-Directed Anticancer Drugs for Pancreatic Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing a novel therapeutic strategy for advanced gastric cancer using the new genetic pathway of HIF-1 alpha.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new treatment for colorectal cancer using the glucose metabolism characteristics.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

FUTを標的とした進行大腸癌に対する抗EMT療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel pancreatic cancer rapid diagnostic method by the fucosyltransferases mRNA detection in peripheral blood

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Relationship Between Increased Fucosylation and2016

Author(s)

Journal Title

Data Source

[Journal Article] A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014

Author(s)

Journal Title

DOI

NAID

Data Source

Osuga Takahiro 大須賀崇裕