Ando Kanae 飯島香奈絵 (安藤香奈絵)

… Alternative Names

安藤香奈絵

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Researcher Number	40632500
Other IDs
Affiliation (Current)	2025: 東京都立大学, 理学研究科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京都立大学, 理学研究科, 准教授 2018 – 2019: 首都大学東京, 理学研究科, 准教授 2015 – 2017: 首都大学東京, 理工学研究科, 准教授
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Studies on the Super-Aging Society / Neurophysiology / General neuroscience Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 46030:Function of nervous system-related
Keywords	Principal Investigator 神経変性疾患 / ショウジョウバエ / 老化 / タウ / ショウジョウバエモデル / タウタンパク質 / 脳神経疾患 / ショウジョウバエ疾患モデル / アルツハイマー病 / 微小管結合タンパク質タウ … More / 神経細胞 / 神経細胞死 / グルコース / 代謝 / 学習・記憶 / memory / dietary restriction / Drosophila / glycolysis / mitochondria / glucose / brain / aging / 脳高次機能 / カロリー制限 / グルコーストランスポーター / 脳 / 糖代謝 / 疾患モデルショウジョウバエ / タンパク質分解 / タンパク質凝集 / 神経科学 / リン酸化 / 認知症 / 遺伝子発現 / 軸索 / ATP / 細胞内局在 / CaMKII / エネルギー代謝 / 軸索輸送 / 加齢 / ミトコンドリア … More Except Principal Investigator 健康寿命 / プロテアソーム / 老化 / LMTK / 神経変性疾患 / 神経回路 / Cdk5 / 高次脳機能 / リン酸化 / スパイン / APP / BACE1 / アルツハイマー病 / 記憶形成 / LMTK1 / エンドソーム / 小胞輸送 / 神経細胞 Less

Neuronal glucose metabolism and agingPrincipal Investigator
- Principal Investigator
  
  飯島香奈絵 (安藤香奈絵)
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan University
プロテアソームによる異常タンパク質分解を活性化して健康寿命を伸ばす
- Principal Investigator
  
  甲斐田大輔
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Toyama
Molecular function and a pathological role of LMTK1, a novel factor regulating spine formation
- Principal Investigator
  
  Hisanaga Shin-ichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Tokyo Metropolitan University
Age-related memory impairment and glucose metabolism in the brainPrincipal Investigator
- Principal Investigator
  
  Ando Kanae
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Tokyo Metropolitan University
Tau aggregation and toxicity in a Drosophila modelPrincipal Investigator
- Principal Investigator
  
  飯島香奈絵 (安藤香奈絵)
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan University
Mechanisms underlying neuronal dysfunction and degeneration caused by loss of presynaptic mitochondriaPrincipal Investigator
- Principal Investigator
  
  Ando Kanae
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Tokyo Metropolitan University
タウ蛋白質の異常代謝開始点から見るタウ蓄積と神経毒性獲得に関わる因子の同定Principal Investigator
- Principal Investigator
  
  飯島香奈絵 (安藤香奈絵)
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan University

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Neuromethods, Chapter: Electron microscopy of the brains of Drosophila Models of Alzheimer’s disease. DOI 10.1007/7657_2015_75,2016
- Author(s)
  Ando, K.*, Hearn, A., Suzuki, E., Maruko-Otake, A., Sekiya, M., and Iijima, K.M.
- Total Pages
  19
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K06712
[Book] Neuromethods, Chapter "Electron microscopy of the brains of Drosophila Models of Alzheimer’s disease."2016
- Author(s)
  Ando, K.*, Hearn, A., Suzuki, E., Maruko-Otake, A., Sekiya, M., and Iijima, K.M. , DOI 10.1007/7657_2015_75, Springer
- Total Pages
  19
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Journal Article] Valproic acid-induced anxiety and depression behaviors are ameliorated in p39 Cdk5 activator-deficient mice.2022
- Author(s)
  Takahashi, M., Takasugi, T., Kawakami, A., Wei, R., Ando, K., Ohshima, T., Hisanaga, S.
- Journal Title
  
  Neurochem Res.
  
  Volume: 47 Issue: 9 Pages: 2773-2779
- DOI
  10.1007/s11064-022-03642-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06942
[Journal Article] Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE12021
- Author(s)
  Komaki Keisuke、Takano Tetsuya、Sato Yutaka、Asada Akiko、Ikeda Shikito、Yamada Kaoru、Wei Ran、Huo Anni、Fukuchi Aoi、Saito Taro、Ando Kanae、Murayama Shigeo、Araki Wataru、Kametani Fuyuki、Hasegawa Masato、Iwatsubo Takeshi、Tomomura Mineko、Fukuda Mitsunori、Hisanaga Shin-ichi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 6 Pages: 729-738
- DOI
  10.1093/jb/mvab094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07836, KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-22K07550, KAKENHI-PROJECT-22K11708, KAKENHI-PROJECT-19K07988, KAKENHI-PROJECT-22H04923
[Journal Article] Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity <i>in vivo</i>2021
- Author(s)
  Saito Taro、Chiku Tomoki、Oka Mikiko、Wada-Kakuda Satoko、Nobuhara Mika、Oba Toshiya、Shinno Kanako、Abe Saori、Asada Akiko、Sumioka Akio、Takashima Akihiko、Miyasaka Tomohiro、Ando Kanae
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 30 Issue: 21 Pages: 1955-1967
- DOI
  10.1093/hmg/ddab162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21593, KAKENHI-PLANNED-18H05414
[Journal Article] 5‐Aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in <i>Drosophila</i>2021
- Author(s)
  Nozawa Naoko、Noguchi Marie、Shinno Kanako、Tajima Maki、Aizawa Shingo、Saito Taro、Asada Akiko、Ishii Takuya、Ishizuka Masahiro、Iijima Koichi M.、Ando Kanae
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 1 Pages: 295-305
- DOI
  10.1002/2211-5463.13338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21593
[Journal Article] Distinct phosphorylation profiles of tau in brains of patients with different tauopathies.2021
- Author(s)
  Samimi, N., Sharma, G., Kimura, T., Matsubara, T., Huo, A., Saito, S., Murayama, M., Akatsu, H., Hashizume, Y., Hasegawa, M., Farjam, M., Shahpasand, K., Ando, K., Hisanaga, S.
- Journal Title
  
  Neurobiol. Aging
  
  Volume: 108 Pages: 72-79
- DOI
  10.1016/j.neurobiolaging.2021.08.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-19K07988, KAKENHI-PROJECT-16H06277
[Journal Article] Increasing neuronal glucose uptake attenuates brain aging and promotes life span under dietary restriction in Drosophila2021
- Author(s)
  Oka Mikiko、Suzuki Emiko、Asada Akiko、Saito Taro、Iijima Koichi M.、Ando Kanae
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 1 Pages: 101979-101979
- DOI
  10.1016/j.isci.2020.101979
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21593, KAKENHI-PROJECT-18J21936
[Journal Article] Isoform-dependent subcellular localization of LMTK1A and LMTK1B and their roles in axon outgrowth and spine formation2020
- Author(s)
  Wei Ran、Sugiyama Arika、Sato Yuta、Nozumi Motohiro、Nishino Hironori、Takahashi Miyuki、Saito Taro、Ando Kanae、Fukuda Mitsunori、Tomomura Mineko、Igarashi Michihiro、Hisanaga Shin-ichi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 1 Pages: 23-32
- DOI
  10.1093/jb/mvaa019
- NAID
  40022279141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06459, KAKENHI-PROJECT-17KK0144, KAKENHI-PUBLICLY-18H04670, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-18H04013
[Journal Article] Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle2020
- Author(s)
  Samimi Nastaran、Asada Akiko、Ando Kanae
- Journal Title
  
  Galen Medical Journal
  
  Volume: 9 Pages: 1681-1681
- DOI
  10.31661/gmj.v9i0.1681
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21593
[Journal Article] Hyperactive and impulsive behaviors of LMTK1 knockout mice2020
- Author(s)
  Takahashi Miyuki、Sugiyama Arika、Wei Ran、Kobayashi Shizuka、Fukuda Kimiko、Nishino Hironori、Takahashi Roka、Tsutsumi Koji、Kita Ichiro、Ando Kanae、Manabe Toshiya、Kamiguchi Hiroyuki、Tomomura Mineko、Hisanaga Shin-ichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15461-15461
- DOI
  10.1038/s41598-020-72304-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06901, KAKENHI-PROJECT-19K06942, KAKENHI-PUBLICLY-19H04876, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-18K10852
[Journal Article] Microtubule affinity?regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration2020
- Author(s)
  Oba Toshiya、Saito Taro、Asada Akiko、Shimizu Sawako、Iijima Koichi M.、Ando Kanae
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 50 Pages: 17138-17147
- DOI
  10.1074/jbc.ra120.014420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21593
[Journal Article] Tau isoform expression and phosphorylation in marmoset brains2019
- Author(s)
  Sharma Govinda、Huo Anni、Kimura Taeko、Shiozawa Seiji、Kobayashi Reona、Sahara Naruhiko、Ishibashi Minaka、Ishigaki Shinsuke、Saito Taro、Ando Kanae、Murayama Shigeo、Hasegawa Masato、Sobue Gen、Okano Hideyuki、Hisanaga Shin-ichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 30 Pages: 11433-11444
- DOI
  10.1074/jbc.ra119.008415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07367, KAKENHI-PROJECT-19K06472, KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-19K06942, KAKENHI-PUBLICLY-19H05437, KAKENHI-WRAPUP-19H05447, KAKENHI-PROJECT-16H06277
[Journal Article] Cyclin-dependent kinase 5 promotes proteasomal degradation of the 5-HT1A receptor via phosphorylation2019
- Author(s)
  Takahashi Miyuki、Kobayashi Yuki、Ando Kanae、Saito Yumiko、Hisanaga Shin-ichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 510 Issue: 3 Pages: 370-375
- DOI
  10.1016/j.bbrc.2019.01.093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05703, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-19K06739, KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-18K14742
[Journal Article] The LMTK1-TBC1D9B-Rab11A cascade regulates dendritic spine formation via endosome trafficking.2019
- Author(s)
  Nishino, H., Saito. T., Wei, R., Takano, T., Tsutsumi, T., Taniguchi, M., Ando, K., Tomomura, M., Fukuda, M., Hisanaga, S.
- Journal Title
  
  J. Neurosci.
  
  Volume: 39 Pages: 9491-9502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06942
[Journal Article] S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy2018
- Author(s)
  Chiku Tomoki、Hayashishita Motoki、Saito Taro、Oka Mikiko、Shinno Kanako、Ohtake Yosuke、Shimizu Sawako、Asada Akiko、Hisanaga Shin-ichi、Iijima Koichi M.、Ando Kanae
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 71 Pages: 255-264
- DOI
  10.1016/j.neurobiolaging.2018.07.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05703, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16K08637
[Journal Article] Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models2018
- Author(s)
  Sekiya Michiko、Wang Minghui、Fujisaki Naoki、Sakakibara Yasufumi、Quan Xiuming、Ehrlich Michelle E.、De Jager Philip L.、Bennett David A.、Schadt Eric E.、Gandy Sam、Ando Kanae、Zhang Bin、Iijima Koichi M.
- Journal Title
  
  Genome Medicine
  
  Volume: 10 Issue: 1 Pages: 26-26
- DOI
  10.1186/s13073-018-0530-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08637, KAKENHI-PUBLICLY-17H05703, KAKENHI-PROJECT-15K06712
[Journal Article] Loss of synaptic mitochondria and dementia.2017
- Author(s)
  Oka, M., Iijima, K.M. and Ando, K.
- Journal Title
  
  実験医学
  
  Volume: 35(12) Pages: 182-185
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Journal Article] Loss of synaptic mitochondria and dementia.2017
- Author(s)
  Oka, M., Iijima, K.M. and Ando, K.
- Journal Title
  
  実験医学
  
  Volume: 35(12) Pages: 182-185
- Data Source
  KAKENHI-PROJECT-15K06712
[Journal Article] EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila2017
- Author(s)
  Sekiya Michiko、Maruko-Otake Akiko、Hearn Stephen、Sakakibara Yasufumi、Fujisaki Naoki、Suzuki Emiko、Ando Kanae、Iijima Koichi M.
- Journal Title
  
  Developmental Cell
  
  Volume: 41 Issue: 6 Pages: 652-664
- DOI
  10.1016/j.devcel.2017.05.019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08637, KAKENHI-PUBLICLY-17H05703, KAKENHI-PROJECT-15K06712
[Journal Article] Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy2017
- Author(s)
  Oka Mikiko、Fujisaki Naoki、Maruko-Otake Akiko、Ohtake Yosuke、Shimizu Sawako、Saito Taro、Hisanaga Shin-Ichi、Iijima Koichi M、Ando Kanae
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 162 Issue: 5 Pages: 335-342
- DOI
  10.1093/jb/mvx038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08637, KAKENHI-PUBLICLY-17H05703, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K06712
[Journal Article] Stabilization of microtubule-unbound tau via tau phosphorylation at Ser262/356 by Par-1/MARK contributes to augmentation of AD-related phosphorylation and Aβ42-induced tau toxicity.2016
- Author(s)
  Ando, K.*, Maruko-Otake, A., Ohtake, Y., Hayashishita, M., Sekiya, M., and Iijima, K. M.
- Journal Title
  
  PLoS Genetics
  
  Volume: 12(3) Issue: 3 Pages: e1005917-e1005917
- DOI
  10.1371/journal.pgen.1005917
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06712, KAKENHI-PUBLICLY-15H01564
[Journal Article] Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.2016
- Author(s)
  Ando K, Oka M, Ohtake M, Hayashishita M, Shimizu S, Hisanaga S, Iijima KM
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 478 (2) Issue: 2 Pages: 929-934
- DOI
  10.1016/j.bbrc.2016.08.053
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01564, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K06712, KAKENHI-PROJECT-16K08637
[Presentation] Enhancement of glucose uptake protects neurons against energetic stresses in aging and disease2022
- Author(s)
  Mikiko Oka and Kanae Ando
- Organizer
  The 99th Annual Meeting of the Physiological Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] The effect of sugar intake on neurodegeneration in a Drosophila model of tau toxicity2021
- Author(s)
  Chihiro Yamamoto and Kanae Ando
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] 神経細胞内ミトコンドリア局在異常は分解機能低下によるタンパク質の蓄積を引き起こす2021
- Author(s)
  真野叶子、鈴木えみ子、三浦ゆり、飯島浩一、安藤香奈絵
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] ‘The Effects of Sugar Intake on Neurodegeneration in a Drosophila Model of Tau Toxicity2021
- Author(s)
  Chihiro Yamamoto, Taro Saito, Akiko Asada, Kanae Ando.
- Organizer
  Cell Bio Virtual 2021-An Online ASCB|EMBO Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Increasing glucose uptake suppresses neurodegeneration in Alzheimer’s Disease model Drosophila2021
- Author(s)
  Mikiko Oka, Koichi M. Iijima and Kanae Ando
- Organizer
  The 44 th Annual Meeting of the Japan Neuroscience Society, Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Neuronal glucose metabolism in brain aging and age-related neurodegenerative diseases2021
- Author(s)
  Kanae Ando
- Organizer
  The 64th Annual Meeting of the Japanese Society for Neurochemistry
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Distinct phosphorylation profiles of tau in brains of patients with different tauopathies2021
- Author(s)
  Nastaran Samimi, Taeko Kimura, Tomoyasu Matsubara, Yuko Saito, Shigeo Murayama, Masato Hasegawa, Kanae Ando, Shin-ichi Hisanaga
- Organizer
  第６４回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K06942
[Presentation] 神経細胞でのミトコンドリア局在異常は翻訳異常とタンパク質蓄積を引き起こす2021
- Author(s)
  真野叶子、鈴木えみ子、三浦ゆり、飯島浩一、安藤香奈絵
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] “Enhancement of neuronal glucose uptake attenuates brain aging and promotes lifespan under dietary restriction.”2020
- Author(s)
  Mikiko Oka, Emiko Suzuki, Koichi M. Iijima, Kanae Ando.
- Organizer
  The 39th Annual Meeting of the Japan Society for Dementia Research, Online, Nov 27, 2020
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Hyperactive and impulsive behaviors of LMTK1 knockout mice2020
- Author(s)
  Takahashi, M., Takahashi, R., Sugiyama, A., Kobayashi, S., Fukuda, K., Nishino, H., Wei, R., Kita, I., Ando, K., Manabe, T., Kamiguchi, H., Tomomura, M., Hisanaga, S.
- Organizer
  第６３回日本神経化学会年会
- Data Source
  KAKENHI-PROJECT-19K06942
[Presentation] Disease-dependent phosphorylation of tau in tauopathies2020
- Author(s)
  Samimi, N., Sharma, G., Kimura, T., Huo, A., Chiba, K., Murayama, S., Akatsu, H., Hashizume, Y., Hasegawa, M., Farjam, M., Shahpasand, K., Ando, K., Hisanaga, S.
- Organizer
  第６３回日本神経化学会年会
- Data Source
  KAKENHI-PROJECT-19K06942
[Presentation] 脳老化とアルツハイマー病の予防・緩和を目指して：加齢による神経細胞のエネルギー欠乏の分子メカニズム（英）Fighting against brain aging and Alzheimer disease: Understanding and counteracting bioenergetic challenges in neurons」2020
- Author(s)
  Kanae Ando
- Organizer
  日本分子生物学会年会 (MBSJ2020 Online) 3PW-02ワークショップ「Facilitating the use of Drosophila in clinical and translational biomedical research
- Invited
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] 脳神経細胞の軸索ミトコンドリアの減少はタンパク質分解機能の低下とユビキチン化タンパク質の蓄積を引き起こす2020
- Author(s)
  真野叶子、鈴木えみ子、飯島浩一、安藤香奈絵
- Organizer
  第63回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Enhancement of neuronal glucose uptake protects against tau-induced neurodegeneration in a Drosophila model of Alzheimer’s disease2020
- Author(s)
  Mikiko Oka, Koichi M. Iijima, Kanae Ando.
- Organizer
  The 44th Annual Meeting of the Molecular Biology Society of Japan, Online, Dec 4, 2020
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] ‘Enhancement of glucose uptake to maintain ATP levels in the brain neurons and reducing circulating glucose levels synergistically antagonize the aging in Drosophila.’ NEURO2019:2019
- Author(s)
  Mikiko Oka, Emiko Suzuki, Koichi M. Iijima, Kanae Ando.
- Organizer
  the 42nd Annual Meeting of the Japan Neuroscience Society and the 62nd Annual Meeting of the Japanese Society for Neurochemistry, Niigata, Japan, July 26, 2019 (Oral presentation)
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Tau phosphorylation at AT8 pathological site during brain development.2019
- Author(s)
  T. Dilina, K. Furusawa, T. Takasugi, S. Ishigaki, K. Ando, G. Sobue, S. Hisanaga.
- Organizer
  ISN/ASN2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06942
[Presentation] ‘Enhancement of glucose uptake and calorie restriction antagonize age-dependent reductions in brain ATP levels and synergistically extend lifespan in Drosophila’2019
- Author(s)
  Mikiko Oka, Emiko Suzuki, Koichi M. Iijima, Kanae Ando.
- Organizer
  Society for Neuroscience the 49th annual meeting, Chicago, USA, October 19, 2019 (Poster presentation)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21593
[Presentation] Tau in marmoset brains, its isoform expression and phosphorylation.2019
- Author(s)
  Sharma, G., Huo, A., Kimura, T., Shiozawa, S., Kobayashi, R., Sahara, N., Ishibashi, M., Ishigaki, S., Saito, T., Ando, K., Murayama, S., Hasegawa, H., Sobue, G., Okano, H., Hisanaga, S.
- Organizer
  AD/PD 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06942
[Presentation] Tau phosphorylation at AT8 pathological site during brain development.2019
- Author(s)
  T. Dilina, K. Furusawa, T. Takasugi, S. Ishigaki, K. Ando, G. Sobue, S. Hisanaga.
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PROJECT-19K06942
[Presentation] 26)Saito T., Oba, T, Shimizu, S., Iijima KM and Ando K. Cdk5 regulates MARK4 activity and synergistically augments pathological tau phosphorylation2018
- Author(s)
  Saito T., Oba, T, Shimizu, S., Iijima KM and Ando K
- Organizer
  the 2018 ASCB|EMBO Meeting (San Diego, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] タウの蓄積におけるエンドソーム選別輸送（ESCRT）複合体構成因子CHMP2Bの役割2018
- Author(s)
  淺田明子、伊藤圭哉、斎藤太郎、久永眞市、飯島浩一、安藤香奈絵
- Organizer
  第41回日本分子生物学会大会　(12月、横浜)
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Roles of cysteine residues in microtubule-associated protein tau in its proteostasis and toxicity in neurons.2018
- Author(s)
  Chiku T., Saito T., Oka M, Asada A, Iijima KM, Takashima A and Ando, K.
- Organizer
  the 2018 ASCB|EMBO Meeting (San Diego, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Increasing glucose uptake in Drosophila brain neurons suppresses the reduction in ATP levels and rescues the decline in neuronal function during aging2018
- Author(s)
  M. Oka , E. Suzuki , S. Hisanaga , KM. Iijima , K Ando
- Organizer
  59th Annual Drosophila Research Conference, April 2018, Philadelphia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] Roles of CaMKII in neurodegeneration caused by depletion of presynaptic mitochondria2018
- Author(s)
  K. Shinno , M. Oka , S. Hisanaga , E. Suzuki , K.M. Iijima , K. Ando
- Organizer
  59th Annual Drosophila Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Increasing glucose uptake in Drosophila brain neurons suppresses the reduction in ATP levels and rescues the decline in neuronal function during aging2018
- Author(s)
  M. Oka , E. Suzuki , S. Hisanaga , KM. Iijima , K Ando
- Organizer
  59 Annual Drosophila Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] アルツハイマー病関連たんぱく質タウの微小管結合領域に存在するCysteine残基がモノマーの蓄積と毒性に果たす役割2018
- Author(s)
  知久　朋樹、岡　未来子、斎藤　太郎、浅田　明子、飯島　浩一、安藤　香奈絵
- Organizer
  第61回日本神経化学会大会（9月、神戸）(口頭発表)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Roles of CaMKII in neurodegeneration caused by depletion of presynaptic mitochondria2018
- Author(s)
  K. Shinno , M. Oka , S. Hisanaga , E. Suzuki , K.M. Iijima , K. Ando
- Organizer
  59th Annual Drosophila Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] Roles of CaMKII in neurodegeneration caused by depletion of presynaptic mitochondria.2018
- Author(s)
  K. Shinno , M. Oka , S. Hisanaga , E. Suzuki , K.M. Iijima , K. Ando
- Organizer
  59th Annual Drosophila Research Conference, April 2018, Philadelphia (Selected as a nanosymposium presentor)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] S6 kinase and insulin/IGF signaling regulates accumulation and toxicity of tau through Ser262 phosphorylation in a Drosophila model of tauopathy2017
- Author(s)
  Kanae Ando, Motoki Hayashishita, Tomoki Chiku, Taro Saito, Akiko Asada, Shin-ichi Hisanaga, & Koichi M Iijima
- Organizer
  第60回日本神経化学会
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Elucidating pathological cascades in tauopathies by using Drosophila models2017
- Author(s)
  Kanae Ando
- Organizer
  International Conference of the Genetics Society of Korea (ICGSK) 2017’ Seoul, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] 軸索ミトコンドリアの欠乏によるショウジョウバエ視神経軸索変性における CaMKIIの役割2017
- Author(s)
  真野　叶子、岡　未来子、浅田　明子、斎藤　太郎、久永　眞市、鈴木　えみ子、飯島浩一, 安藤香奈絵
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] インスリン/インスリン様成長因子（IGF）シグナリングのタウのリン酸化と毒性における役割2017
- Author(s)
  林下　幹輝、斎藤　太郎、浅田　明子、久永　眞市、飯島浩一、安藤　香奈絵
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Mechanisms underlying age-dependent reduction in ATP levels in Drosophila brain neurons2017
- Author(s)
  Mikiko Oka, Emiko Suzuki, Shin-Ichi Hisanaga, Koichi Iijima, and Kanae Ando
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] タウによる神経変性におけるESCRTIII complexの役割2017
- Author(s)
  伊藤圭哉、浅田明子、斎藤　太郎、久永　眞市、飯島浩一、安藤　香奈絵
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Elucidating pathological cascades in tauopathies by using Drosophila models2017
- Author(s)
  Kanae Ando
- Organizer
  International Conference of the Genetics Society of Korea (ICGSK) 2017’ Seoul, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] CaMKII enhances tau-mediated neurodegeneration downstream of tau phosphorylation in transgenic Drosophila models of tauopathy.2017
- Author(s)
  Ando*, K., Oka, M., Maruko-Otake, A., Ohtake, Y., Sekiya, M., Hisanaga, S., Iijima, K.M.
- Organizer
  The 4th Asia-Pacific Drosophila Research Conference, Suita, Osaka, Japan, May 10, 2017.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] ‘Increasing glucose uptake suppresses age-dependent reductions in ATP levels in brain neurons and behavioral deficits in Drosophila’2017
- Author(s)
  Mikiko Oka, Emiko Suzuki, Hiromi Imamura, Shin-ichi Hisanaga, Koichi M. Iijima and Kanae Ando
- Organizer
  ASCB/EMBO 2017 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] CaMKII enhances tau-mediated neurodegeneration downstream of tau phosphorylation in transgenic Drosophila models of tauopathy.2017
- Author(s)
  Ando*, K., Oka, M., Maruko-Otake, A., Ohtake, Y., Sekiya, M., Hisanaga, S., Iijima, K.M.
- Organizer
  The 4th Asia-Pacific Drosophila Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] Mechanisms underlying age-dependent reduction in ATP levels in Drosophila brain neurons.2017
- Author(s)
  Oka, M., Suzuki, E., Hisanaga, S., Iijima, K.M., Ando, K.
- Organizer
  The 4th Asia-Pacific Drosophila Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] 微小管結合タンパク質タウシステイン残基の、タウ安定性と毒性における役割2017
- Author(s)
  Tomoki Chiku, Mikiko Oka, Taro Saito, Akio Sumioka, Akiko Asada, Shin-ichi Hisanaga, Koichi M. Iijima, Akihiko Takashima and Kanae Ando
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PUBLICLY-17H05703
[Presentation] “Reduction in ATP levels in the axon during aging and the role of mitochondrial distribution.”2016
- Author(s)
  Oka, M., Suzuki, E., Hisanaga, S.-i., Iijima, KM, and Ando., K.
- Organizer
  59th Annual Meeting of The Japanese Society for Neurochemistry
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] Sustained activation of CaMKII caused by depletion of mitochondria from the axon enhances tau toxicity. (selected for oral presentation at nano symposium)2016
- Author(s)
  Ando, K., Maruko-Otake, A., Hayashishita, M., Oka, M., Ohtake, Y., Sekiya, M., Saito, T., Hisanaga, S., and Iijima, KM.
- Organizer
  46th annual meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] Sustained activation of CaMKII caused by depletion of mitochondria from the axon enhances tau toxicity.2016
- Author(s)
  Ando, K., Maruko-Otake, A., Hayashishita, M., Oka, M., Ohtake, Y., Sekiya, M., Saito, T., Hisanaga, S., and Iijima, KM.
- Organizer
  46th annual meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] “Reduction in ATP levels in the axon during aging and the role of mitochondrial distribution.”2016
- Author(s)
  Oka,M., Suzuki, E., Hisanaga, S., Iijima, KM, and Ando., K.
- Organizer
  46th annual meeting of Society for Neuroscience,
- Place of Presentation
  San Diego, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] Ribosomal protein S6 kinaseはアルツハイマー病関連Ser262サイトのリン酸化を介してタウタンパク質を安定化し毒性を悪化させる。2016
- Author(s)
  林下幹輝、斎藤太郎、久永眞市、飯島浩一、安藤香奈絵.
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] “Reduction in ATP levels in the axon during aging and the role of mitochondrial distribution.” (selected for oral presentation at nano symposium)2016
- Author(s)
  Oka,M., Suzuki, E., Hisanaga, S., Iijima, KM, and Ando., K.
- Organizer
  46th annual meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] “Reduction in ATP levels in the axon during aging and the role of mitochondrial distribution.”2016
- Author(s)
  Oka, M., Suzuki, E., Hisanaga, S.-i., Iijima, KM, and Ando., K.
- Organizer
  59th Annual Meeting of The Japanese Society for Neurochemistry
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] “Tau phosphorylation via microtubule affinity regulating kinase MARK/PAR1 as an initial step in the pathological cascade leading to neurodegeneration”2015
- Author(s)
  Ando, K. *, Hayashishita, M., Oka,M., Maruko-Otake, A., Ohtake, Y., Iijima, K.M.
- Organizer
  The 58th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  埼玉
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] “Sustained activation of CaMKII mediates neurodegeneration caused by depletion of axonal mitochondria”2015
- Author(s)
  Mikiko Oka*1, Akiko Maruko-Otake2, Yosuke Ohtake2, Naoya Yamaguchi1, Michiko Sekiya3, Koichi M. Iijima3, Kanae Ando1
- Organizer
  38th Annual meeting for the Molecular Biology Society in Japan
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] Sustained activation of CaMKII mediates enhancement of tau toxicity caused by depletion of mitochondria from the axon2015
- Author(s)
  Motoki Hayashishita*1, Akiko Maruko-Otake2, Yosuke Ohtake3, Michiko Sekiya4, Koichi M. Iijima4 and Kanae Ando1
- Organizer
  38th Annual meeting for the Molecular Biology Society in Japan　(Joint meeting with JBS)
- Place of Presentation
  兵庫県、神戸市、神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] “Sustained activation of CaMKII mediates enhancement of tau toxicity caused by depletion of mitochondria from the axon”2015
- Author(s)
  Motoki Hayashishita*1, Akiko Maruko-Otake2, Yosuke Ohtake3, Michiko Sekiya4, Koichi M. Iijima4 and Kanae Ando1
- Organizer
  38th Annual meeting for the Molecular Biology Society in Japan,
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06712
[Presentation] Pathological stabilization of tau through phosphorylation at Ser262/356 by Par-1/MARK contributes to abnormal metabolism and toxicity of tau caused by Aβ42”2015
- Author(s)
  Ando, K.*, Maruko-Otake, A., Ohtake, Y., Hayashishita, M., Sekiya, M. and Iijima, K. M. Nagoya, Japan
- Organizer
  Brain Protein Aging and Dementia Control 　The 1st Internatinal Symposium of “Brain Protein Aging and Dementia Control
- Place of Presentation
  愛知県、名古屋市、名古屋大学
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] Tau phosphorylation via microtubule affinity regulating kinase MARK/PAR1 as an initial step in the pathological cascade leading to neurodegeneration”2015
- Author(s)
  Ando, K. *, Hayashishita, M., Oka,M., Maruko-Otake, A., Ohtake, Y., Iijima, K.M.
- Organizer
  The 58th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  埼玉県、大宮市、大宮ソニックシティ
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PUBLICLY-15H01564
[Presentation] “Pathological stabilization of tau through phosphorylation at Ser262/356 by Par-1/MARK contributes to abnormal metabolism and toxicity of tau caused by Aβ42”2015
- Author(s)
  Ando, K.*, Maruko-Otake, A., Ohtake, Y., Hayashishita, M., Sekiya, M. and Iijima, K. M.Nagoya, Japan
- Organizer
  The 1st Internatinal Symposium of “Brain Protein Aging and Dementia Control”,
- Place of Presentation
  名古屋
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K06712

1. Hisanaga Shin-ichi (20181092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 甲斐田大輔 (60415122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 東田千尋 (10272931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 伊野部智由 (50568855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 石神健 (70292787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NOZUMI Motohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ARAKI Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 飯島浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 伊藤泰行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 石垣診祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 小林静香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ando Kanae 飯島 香奈絵 (安藤 香奈絵)

安藤香奈絵

Research Projects

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Neuronal glucose metabolism and agingPrincipal Investigator

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プロテアソームによる異常タンパク質分解を活性化して健康寿命を伸ばす

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Molecular function and a pathological role of LMTK1, a novel factor regulating spine formation

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Age-related memory impairment and glucose metabolism in the brainPrincipal Investigator

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Tau aggregation and toxicity in a Drosophila modelPrincipal Investigator

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Mechanisms underlying neuronal dysfunction and degeneration caused by loss of presynaptic mitochondriaPrincipal Investigator

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タウ蛋白質の異常代謝開始点から見るタウ蓄積と神経毒性獲得に関わる因子の同定Principal Investigator

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[Book] Neuromethods, Chapter: Electron microscopy of the brains of Drosophila Models of Alzheimer’s disease. DOI 10.1007/7657_2015_75,2016

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[Book] Neuromethods, Chapter "Electron microscopy of the brains of Drosophila Models of Alzheimer’s disease."2016

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[Journal Article] Valproic acid-induced anxiety and depression behaviors are ameliorated in p39 Cdk5 activator-deficient mice.2022

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[Journal Article] Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE12021

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[Journal Article] Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity <i>in vivo</i>2021

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[Journal Article] 5‐Aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in <i>Drosophila</i>2021

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[Journal Article] Distinct phosphorylation profiles of tau in brains of patients with different tauopathies.2021

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Ando Kanae 飯島香奈絵 (安藤香奈絵)