Sakimoto Yuya 崎本裕也

… Alternative Names

SAKIMOTO Yuya 崎本裕也

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Researcher Number	40634390
Other IDs
Affiliation (Current)	2025: 愛知県医療療育総合センター発達障害研究所, 遺伝子医療研究部, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2023: 山口大学, 大学院医学系研究科, 講師 2017 – 2018: 山口大学, 大学院医学系研究科, 助教 2014 – 2016: 山口大学, 医学(系)研究科(研究院), 助教 2015: 山口大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Experimental psychology Except Principal Investigator Environmental physiology(including physical medicine and nutritional physiology) / Basic Section 48020:Physiology-related
Keywords	Principal Investigator 海馬CA1 / GABAA受容体 / hippocampus / 海馬 / patch clamp / エピソード記憶 / learning / シナプス / GABAA受容体β3 / ラット … More / リン酸化 / 抑制性シナプス / 文脈学習 / 脳・神経 / 行動学 / mIPSC / mEPSC / GABAの脱抑制 / 回避学習課題 / GABA / miniature E(I)PSC / 回避学習 / シナプス可塑性 / ニューロン … More Except Principal Investigator シナプス可塑性 / GABAA受容体 / AMPA受容体 / 学習・記憶 / super burst / entropy / contextual learning / self-entropy / AMPA receptor / GABAA receptor / エピソード記憶 / アセチルコリン / GABA / グルタミン酸 / AI機械学習 / AI・深層学習 / 自己エントロピー / 海馬CA1ニューロン / 多ニューロン発火活動 / episodic experience / neural code / decoding / 抑制性シナプス / 興奮性シナプス / リップル波 / リップル発火 / 海馬CA1 / memory encoding / synaptic diversity / ripple firings / エピソード学習 / stress / CA1 / リップル / 海馬学習 / 学習、記憶 / diversity / information theory / synaptic plasticity / glutamate / learning and memory / 学習 / エントロピー / 回避学習 / パッチクランプ法 / ストレス Less

光受容タンパクLOV2-Jαを用いたGABAA受容体β3Ser408-409リン酸化と学習の光制御Principal Investigator
- Principal Investigator
  
  崎本裕也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Contextual learning requires phosphorylation at Ser408-409 of GABAA receptor beta3 subunitPrincipal Investigator
- Principal Investigator
  
  Sakimoto Yuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Learning-promoted synaptic diversity and a possible encording rule of CA1 pyramidal neurons
- Principal Investigator
  
  Mitsushima Dai
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Diversity of CA1 synapses and the self-entropy analysis after contexual learning
- Principal Investigator
  
  MITSUSHIMA Dai
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Yamaguchi University
Encoding of episodic memory triggers rapid synaptic plasticity in the hippocampal CA1Principal Investigator
- Principal Investigator
  
  SAKIMOTO Yuya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental psychology
- Research Institution
  Yamaguchi University
Dynamic change of hippocampal theta activity and synaptic plasticity with the memory encoding for negative episodePrincipal Investigator
- Principal Investigator
  
  SAKIMOTO Yuya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental psychology
- Research Institution
  Yamaguchi University
Cholinergic trigger drives synaptic plasticity for stress avoidance task
- Principal Investigator
  
  MITSUSHIMA Dai
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Yamaguchi University

All 2024 2023 2022 2021 2020 2019 2017 2016 2014 Other

All Journal Article Presentation

[Journal Article] Motor training promotes both synaptic and intrinsic plasticity of layer V pyramidal neurons in the primary motor cortex.2023
- Author(s)
  Kida H, Kawakami R, Sakai K, Otaku H, Imamura K, Han-Thiri-Zin, Sakimoto Y, Mitsushima D.
- Journal Title
  
  The Journal of Physiology
  
  Volume: 601(2) Issue: 2 Pages: 335-353
- DOI
  10.1113/jp283755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11168, KAKENHI-PROJECT-20K07276
[Journal Article] A critical period for learning and plastic changes at hippocampal CA1 synapses2022
- Author(s)
  Sakimoto Yuya、Shintani Ako、Yoshiura Daiki、Goshima Makoto、Kida Hiroyuki、Mitsushima Dai
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 7199-7199
- DOI
  10.1038/s41598-022-10453-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03402, KAKENHI-PROJECT-20K07276
[Journal Article] Diversity of learning-induced synaptic plasticity at dorsal CA1 synapses: a possible underlying mechanism of contextual memory formation2022
- Author(s)
  Paw-Min-Thein-Oo、Sakimoto Yuya、Mitsushima Dai
- Journal Title
  
  Medical Research Archives
  
  Volume: 10 Issue: 1 Pages: 1-12
- DOI
  10.18103/mra.v10i1.2623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03402
[Journal Article] Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology2021
- Author(s)
  Sakimoto Yuya、Paw Min-Thein-Oo、Goshima Makoto、Kanehisa Itsuki、Tsukada Yutaro、Mitsushima Dai
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 22 Pages: 12456-12456
- DOI
  10.3390/ijms222212456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03402
[Journal Article] Androgen affects the inhibitory avoidance memory by primarily acting on androgen receptor in the brain in adolescent male rats2021
- Author(s)
  Md Nabiul Islam, Yuya Sakimoto, Mir Rubayet Jahan, Emi Miyasato, Abu Md Mamun Tarif, Kanako Nozaki, Koh-hei Masumoto, Akie Yanai, Dai Mitsushima, Koh Shinoda
- Journal Title
  
  Brain Sciences
  
  Volume: 1(2) Issue: 2 Pages: 239-239
- DOI
  10.3390/brainsci11020239
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16108, KAKENHI-PROJECT-19H03402, KAKENHI-PROJECT-18K06340, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-19K02318
[Journal Article] Proximodistal heterogeneity in learning-promoted pathway-specific plasticity at dorsal CA1 synapses.2020
- Author(s)
  Paw-Min-Thein-Oo, Sakimoto Y, Kida H, Mitsushima D.
- Journal Title
  
  Neuroscience
  
  Volume: 437 Pages: 184-194
- DOI
  10.1016/j.neuroscience.2020.04.040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03402
[Journal Article] Androgen Affects the Dynamics of Intrinsic Plasticity of Pyramidal Neurons in the CA1 Hippocampal Subfield in Adolescent Male Rats.2020
- Author(s)
  Islam MN, Sakimoto Y, Jahan MR, Ishida M, Mamun Tarif AM, Nozaki K, Masumoto KH, Yanai A, Mitsushima D, Shinoda K.
- Journal Title
  
  Neuroscience. 2020 May 23:S0306-4522(20)30319-5.
  
  Volume: 20 Pages: 15-29
- DOI
  10.1016/j.neuroscience.2020.05.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K02318, KAKENHI-PROJECT-18K15006, KAKENHI-PROJECT-20K16108, KAKENHI-PROJECT-19H03402, KAKENHI-PROJECT-18K06340, KAKENHI-PROJECT-19K17112
[Journal Article] Learning promotes subfield-specific synaptic diversity in hippocampal CA1 neurons.2019
- Author(s)
  Sakimoto Y, Mizuno J, Kida H, Kamiya Y, Ono Y, Mitsushima D.
- Journal Title
  
  Cerebral Cortex
  
  Volume: in press Issue: 5 Pages: 2183-2195
- DOI
  10.1093/cercor/bhz022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10710, KAKENHI-PROJECT-16H05129, KAKENHI-PROJECT-19H03985, KAKENHI-PROJECT-19H01091
[Journal Article] Temporal dynamics of learning-promoted synaptic diversity in CA1 pyramidal neurons.2019
- Author(s)
  Sakimoto Y, Kida H, Mitsushima D.
- Journal Title
  
  FASEB J.
  
  Volume: 33(12) Issue: 12 Pages: 14382-14393
- DOI
  10.1096/fj.201801893rrr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10710, KAKENHI-PROJECT-19H03402
[Journal Article] Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity2017
- Author(s)
  Kida Hiroyuki、Sakimoto Yuya、Mitsushima Dai
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 129 Issue: 129 Pages: 1-11
- DOI
  10.3791/55876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05129, KAKENHI-PROJECT-15K01501, KAKENHI-PROJECT-16K17362
[Journal Article] Examination of configural association theory and conflict resolution model through hippocampal theta activity2016
- Author(s)
  Sakimoto Y, Mitsushima D
- Journal Title
  
  Neurotransmitter
  
  Volume: 3 Pages: 1-8
- DOI
  10.14800/nt.1478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05129
[Journal Article] Examination of configural association theory and conflict resolution model through hippocampal theta activity2016
- Author(s)
  Yuya Sakimoto, Dai Mitsushima
- Journal Title
  
  Neurotransmitter
  
  Volume: 3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K17362
[Journal Article] Developmental trajectory of contextual learning and 24-h acetylcholine release in the hippocampus.2014
- Author(s)
  Takase K, Sakimoto Y, Kimura F, Mitsushima D.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 3738-3738
- DOI
  10.1038/srep03738
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460314, KAKENHI-PROJECT-25460317, KAKENHI-PUBLICLY-26115518
[Presentation] Contextual learning requires phosphorylation at Ser408-409 of β3 subunit2024
- Author(s)
  Yuya Sakimoto, Hideji Murakoshi ,Mitsushima Dai
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K06347
[Presentation] 文脈学習を成立には Ser408 － 409 of GABAA receptor β 3 subunit リン酸化が必要2023
- Author(s)
  﨑本裕也
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K07276
[Presentation] Contextual training enhances synaptic plasticity at both temporoammonic and Schaffer pathways onto CA1 neurons.2017
- Author(s)
  Paw Min Thein Oo, Yuya Sakimoto, Dai Mitsushima
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] Contextual training enhances synaptic plasticity at both temporoammonic and Schaffer pathways onto CA1 neurons2017
- Author(s)
  Paw Min Thein Oo, Yuya Sakimoto, Dai Mitsushima
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター (静岡県・浜松市)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] 文脈学習は、海馬CA1内で部位特異的にシナプスの自己エントロピーを増大させる2017
- Author(s)
  水野潤造，崎本裕也，木田裕之，小野弓絵，紙谷義孝，美津島大
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター (静岡県・浜松市)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] Contextual learning increases subfield-specific self-entropy at hippocampal CA1 synapses2017
- Author(s)
  Junzo Mizuno, Yuya Sakimoto, Hiroyuki Kida, Yumie Ono, Yoshinori Kamiya, Dai Mitsushima
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] Developmental changes in the learning-induced plasticity at hippocampal CA1 synapses2017
- Author(s)
  Ako Matsumoto, Yuya Sakimoto, Hiroyuki Kida, Dai Mitsushima
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] Disinhibition from GABA and rapid strengthening of hippocampal CA1 synapses after contextual training.2017
- Author(s)
  Yuya Sakimoto, Hiroyuki Kida, Dai Mitsushima
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] 海馬CA1における、文脈学習直後のGABA分泌量低下とシナプスの多様化2017
- Author(s)
  﨑本裕也，木田裕之，美津島大
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター (静岡県・浜松市)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] 回避学習による海馬CA1のシナプス可塑性と発達変化2017
- Author(s)
  松元耶子，崎本裕也，美津島大
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター (静岡県・浜松市)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K17362
[Presentation] Rapid synaptic plasticity within 5 min: experienced episode increases diversity of excitatory and inhibitory synapses in the hippocampal CA12016
- Author(s)
  Sakimoto Y, Mitsushima D.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道札幌市札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460314
[Presentation] 学習による海馬CA1のシナプス強化は 5分以内に起きる：エピソード経験が生み出す興奮と抑制のシナプス多様性2016
- Author(s)
  﨑本裕也，美津島大
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26780419
[Presentation] Learning-dependent synaptic diversity in hippocampal CA1 neurons: encoding of context but not retrieval induces rapid plasticity at excitatory and inhibitory synapses2014
- Author(s)
  Sakimoto Y, Mitsushima D.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25460314
[Presentation] Learning-dependent synaptic plasticity at CA1 synapses: laterality and a possible location of contextual memory in the hippocampus2014
- Author(s)
  Mizuno J, Sakimoto Y, Kida H, Ono Y, Kamiya Y, Mitsushima D.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25460314
[Presentation] Learning-dependent synaptic plasticity at CA1 synapses: laterality and a possible location of contextual memory in the hippocampus.
- Author(s)
  Mizuno J, Sakimoto Y, Kida H, Ono Y, Kamiya Y, Mitsushima D.
- Organizer
  北米神経科学大会
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460314
[Presentation] Learning-dependent synaptic diversity in hippocampal CA1 neurons: encoding of context but not retrieval induces rapid plasticity at excitatory and inhibitory synapses.
- Author(s)
  Sakimoto Y, Mitsushima D.
- Organizer
  北米神経科学大会
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460314
[Presentation] Contextual memory encoding induces a quick change of post synaptic current in hippocampal CA1 neuron
- Author(s)
  﨑本裕也
- Organizer
  日本生理学会
- Place of Presentation
  神戸国際会議場 (兵庫県・神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26780419
[Presentation] Learning-dependent synaptic diversity in hippocampal CA1 neurons: Encoding of context plasticity at excitatory and inhibitory synapses.
- Author(s)
  﨑本裕也
- Organizer
  Society for Neuroscience
- Place of Presentation
  ワシントン (USA)
- Year and Date
  2014-11-14 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26780419

1. MITSUSHIMA Dai (70264603)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. KIDA Hiroyuki (70432739)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
3. ISHIKAWA Junko (30570808)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 西井淳 (00242040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村井礼 (30279111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 呉本尭 (40294657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Md・Nabiul Islam

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 柳井章江

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 篠田晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakimoto Yuya 崎本 裕也

SAKIMOTO Yuya 崎本 裕也

Research Projects

Research Products

Co-Researchers

光受容タンパクLOV2-Jαを用いたGABAA受容体β3Ser408-409リン酸化と学習の光制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Contextual learning requires phosphorylation at Ser408-409 of GABAA receptor beta3 subunitPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Learning-promoted synaptic diversity and a possible encording rule of CA1 pyramidal neurons

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diversity of CA1 synapses and the self-entropy analysis after contexual learning

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Encoding of episodic memory triggers rapid synaptic plasticity in the hippocampal CA1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamic change of hippocampal theta activity and synaptic plasticity with the memory encoding for negative episodePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cholinergic trigger drives synaptic plasticity for stress avoidance task

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Motor training promotes both synaptic and intrinsic plasticity of layer V pyramidal neurons in the primary motor cortex.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A critical period for learning and plastic changes at hippocampal CA1 synapses2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diversity of learning-induced synaptic plasticity at dorsal CA1 synapses: a possible underlying mechanism of contextual memory formation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Androgen affects the inhibitory avoidance memory by primarily acting on androgen receptor in the brain in adolescent male rats2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proximodistal heterogeneity in learning-promoted pathway-specific plasticity at dorsal CA1 synapses.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Androgen Affects the Dynamics of Intrinsic Plasticity of Pyramidal Neurons in the CA1 Hippocampal Subfield in Adolescent Male Rats.2020

Author(s)

Journal Title

Sakimoto Yuya 崎本裕也

SAKIMOTO Yuya 崎本裕也