Nakamura Masahiro 中村正裕

Researcher Number	40634449
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2023: 東京大学, 大学院工学系研究科(工学部), 特任助教 2018: 東京大学, 大学院工学系研究科(工学部), 特任研究員 2016 – 2017: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related / Genome biology Except Principal Investigator Basic Section 56060:Ophthalmology-related / Basic Section 49020:Human pathology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Mathematical Sciences in Search of New Cooperation
Keywords	Principal Investigator シングルセル / クロマチン / 褐色脂肪細胞 / 遺伝子発現 / 再生医学 / エピゲノム / 心筋細胞 / クロマチン構造 / 心筋 Except Principal Investigator ドライアイ … More / マルチオミクス / 機械学習 / 不均一性 / 可塑性 / 眼免疫 / 制御性T細胞 / 多重蛍光染色 / 分子病理疫学 / ヒト / 疫学コホート / 腫瘍免疫 / 膵癌 / GWAS / バイオバンク / モバイルヘルス / ゲノミクス / 免疫 / 多様性 / 炎症 / マルチオミクス機械学習 / RNAseq / 角膜移植 / 免疫寛容 / マルチオミクス解析 / 角膜 / 角膜上皮細胞 / 細胞老化 / 角化 / 擬似時間軸 / 力学系 / 多能性幹細胞 / 心筋分化 / ヘテロジェネイティ / 1細胞遺伝子発現解析 / 遺伝子発現のゆらぎ / 1細胞 Less

モバイルヘルスとゲノミクスの融合によるドライアイの多様性理解と層別化医療の実現
- Principal Investigator
  
  猪俣武範
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Juntendo University
ヒト膵癌の免疫微小環境の超多重染色と大規模コホート解析による新規治療戦略の確立
- Principal Investigator
  
  濱田毅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  The University of Tokyo
角化と非角化を制御する分子メカニズム機構の解明
- Principal Investigator
  
  北澤耕司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
マルチオミクス機械学習による制御性T細胞の可塑性と不均一性の解明
- Principal Investigator
  
  猪俣武範
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Juntendo University
Multi-Omics Profiling of the Dry Eye Microenvironment to explore the Plasticity and Heterogeneity of Immune Cells
- Principal Investigator
  
  猪俣武範
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Juntendo University
Identification of Transcription factors in brown adipose cell differentiation by single-nucleus chromatin analysisPrincipal Investigator
- Principal Investigator
  
  NAKAMURA MASAHIRO
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  The University of Tokyo
Identification of chromatin regulatory mechanism in heart development.Principal Investigator
- Principal Investigator
  
  Nakamura Masahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  The University of Tokyo
  Kyoto University
Analysis of cell-to-cell variability in pluripotent stem cells by single-cell gene expression analysis and mathematical modeling
- Principal Investigator
  
  Nakamura Naotoshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Mathematical Sciences in Search of New Cooperation
- Research Institution
  Osaka University
  Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Dyslipidemia Exacerbates Meibomian Gland Dysfunction: A Systematic Review and Meta-Analysis2023
- Author(s)
  Tomioka Yasufumi、Kitazawa Koji、Yamashita Yohei、Numa Kohsaku、Inomata Takenori、Hughes Jun-Wei B.、Soda Rina、Nakamura Masahiro、Suzuki Tomo、Yokoi Norihiko、Sotozono Chie
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 6 Pages: 2131-2131
- DOI
  10.3390/jcm12062131
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09748
[Journal Article] Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model2022
- Author(s)
  Zhu J, Inomata T, Nakamura M, Fujimoto K, Akasaki Y, Fujio K, Yanagawa A, Uchida K, Sung J, Negishi N, Nagino K, Okumura Y, Miura M, Shokirova H, Kuwahara M, Hirosawa K, Midorikawa-Inomata A, Eguchi A, Huang T, Yagita H, Habu S, Okumura K, Murakami A.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 4853-4853
- DOI
  10.1038/s41598-022-08949-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09810, KAKENHI-PROJECT-19K18041
[Journal Article] Prevalence of Comorbidity between Dry Eye and Allergic Conjunctivitis: A Systematic Review and Meta-Analysis2022
- Author(s)
  Akasaki Yasutsugu、Inomata Takenori、Sung Jaemyoung、Nakamura Masahiro、Kitazawa Koji、Shih Kendrick Co、Adachi Takeya、Okumura Yuichi、Fujio Kenta、Nagino Ken、Midorikawa-Inomata Akie、Kuwahara Mizu、Hirosawa Kunihiko、Huang Tianxiang、Morooka Yuki、Shokirova Hurramhon、Eguchi Atsuko、Murakami Akira
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 13 Pages: 3643-3643
- DOI
  10.3390/jcm11133643
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09748
[Journal Article] Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application2021
- Author(s)
  Eguchi Atsuko、Inomata Takenori、Nakamura Masahiro、Nagino Ken、Iwagami Masao、Sung Jaemyoung、Midorikawa-Inomata Akie、Okumura Yuichi、Fujio Kenta、Fujimoto Keiichi、Miura Maria、Akasaki Yasutsugu、Shokirova Hurramhon、Hirosawa Kunihiko、Kuwahara Mizu、Zhu Jun、Dana Reza、Murakami Akira、Kobayashi Hiroyuki
- Journal Title
  
  Japanese Journal of Ophthalmology
  
  Volume: 65 Issue: 2 Pages: 271-281
- DOI
  10.1007/s10384-020-00798-1
- Data Source
  KAKENHI-PROJECT-20K23168, KAKENHI-PROJECT-20KK0207
[Journal Article] Using Medical Big Data to Develop Personalized Medicine for Dry Eye Disease2020
- Author(s)
  Inomata Takenori、Sung Jaemyoung、Nakamura Masahiro、Iwagami Masao、Okumura Yuichi、Iwata Nanami、Midorikawa-Inomata Akie、Fujimoto Keiichi、Eguchi Atsuko、Nagino Ken、Fujio Kenta、Miura Maria、Shokirova Hurramhon、Murakami Akira
- Journal Title
  
  Cornea
  
  Volume: 39 Issue: 1 Pages: S39-S46
- DOI
  10.1097/ico.0000000000002500
- Data Source
  KAKENHI-PROJECT-20KK0207
[Journal Article] LAVENDER: latent axes discovery from multiple cytometry samples with non-parametric divergence estimation and multidimensional scaling reconstruction2019
- Author(s)
  Nakamura Naotoshi、Okada Daigo、Setoh Kazuya、Kawaguchi Takahisa、Higasa Koichiro、Tabara Yasuharu、Matsuda Fumihiko、Yamada Ryo
- Journal Title
  
  bioRxiv
  
  Volume: 1 Pages: 673434-673434
- DOI
  10.1101/673434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16KT0139
[Journal Article] Precision Health (プレシジョン・ヘルス, 精密保健)の実現に向けて2018
- Author(s)
  中村正裕
- Journal Title
  
  IoMT学会誌（メディカルレビュー社）
  
  Volume: 1
- Data Source
  KAKENHI-PROJECT-16KT0139
[Journal Article] 心筋分化過程を描写するシングルセル遺伝子発現解析2017
- Author(s)
  中村正裕、吉田善紀、渡辺亮
- Journal Title
  
  細胞
  
  Volume: 5月増刊号
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] Role of human senescent corneal,conjunctival epithelial cells2023
- Author(s)
  Yamashita Y, Kitazawa K, Numa K, Nakamura M, Tomioka Y, Hughes JWB, Desprez PV, Sotozono C, Campisi J
- Organizer
  The Association for Research in Vision and Ophthalmology (ARVO) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09748
[Presentation] Anti-CD80/86 antibodies suppress inflammatory reaction and improve grafts survival in a high-risk murine corneal transplantation model2021
- Author(s)
  Akasaki Y, Inomata T, Zhu J, Nakamura M, Fujimoto K, Fujio K, Yanagawa A, Uchida K, Sung J, Negishi N, Nagano K, Okumura Y, Miura M, Shokirova H, Kuwahara M, Hirosawa K, Midorikawa-Inomata A, Eguchi A, Huang T, Yagita H, Habu S, Okumura K, Murakami A
- Organizer
  The 14th Joint Meeting of Japan-China-Korea Ophthalmologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09810
[Presentation] Heterogeneity and its hierarchy of Prrx1-positive cells during limb development2019
- Author(s)
  Nakamura M, Hojo H, Kawabe.K, Takarada.T
- Organizer
  Cell Symposia "Single Cells: Technology to Biology"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] Heterogeneity and its hierarchy of Prrx1-positive cells during limb development2019
- Author(s)
  Masahiro Nakamura
- Organizer
  Cell Symposium: Single Cells: Technology to Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15040
[Presentation] 実空間や情報空間の『形』を観る方法の開発2019
- Author(s)
  Naotoshi Nakamura
- Organizer
  日本応用数理学会研究部会連合会発表会
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] 実空間や情報空間の「形」を観る方法の開発2019
- Author(s)
  中村直俊
- Organizer
  生理研研究会「シグナル動態の可視化と操作に基づく多階層機能解析の新展開」
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] 距離に基づく細胞間不均一性の解析2019
- Author(s)
  Naotoshi Nakamura
- Organizer
  第11回光塾
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] Heterogeneity and its hierarchy of Prrx1-positive cells during limb development2019
- Author(s)
  Masahiro Nakamura
- Organizer
  Cell Symposia (Single Cells: Technology to Biology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] 季節性インフルエンザワクチンに対する免疫応答から個人差を抽出する＋細胞の動く軌跡の空間の形2018
- Author(s)
  中村直俊
- Organizer
  第5回先進イメージング医学研究会（第15回生体イメージング研究会）
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] LAVENDER extracts individual variability in the immune response to seasonal influenza vaccination2018
- Author(s)
  Naotoshi Nakamura
- Organizer
  From Molecules and Cells to Human Health: Ideas and concepts
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0139
[Presentation] シングルセルマルチオミックス～心筋分化におけるシングルセル発現解析とオープンクロマチン解析～2016
- Author(s)
  中村正裕
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0139

1. 猪俣武範 (10645667)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. Nakamura Naotoshi (30554472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. 北澤耕司 (10760803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 藤本啓一 (10876684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 布施昇男 (10302134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 清水厚志 (30327655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 濱田毅 (90723461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 眞杉洋平 (90528598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 猪俣明恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Masahiro 中村 正裕

Research Projects

Research Products

Co-Researchers

モバイルヘルスとゲノミクスの融合によるドライアイの多様性理解と層別化医療の実現

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト膵癌の免疫微小環境の超多重染色と大規模コホート解析による新規治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

角化と非角化を制御する分子メカニズム機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マルチオミクス機械学習による制御性T細胞の可塑性と不均一性の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multi-Omics Profiling of the Dry Eye Microenvironment to explore the Plasticity and Heterogeneity of Immune Cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Transcription factors in brown adipose cell differentiation by single-nucleus chromatin analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of chromatin regulatory mechanism in heart development.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cell-to-cell variability in pluripotent stem cells by single-cell gene expression analysis and mathematical modeling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dyslipidemia Exacerbates Meibomian Gland Dysfunction: A Systematic Review and Meta-Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prevalence of Comorbidity between Dry Eye and Allergic Conjunctivitis: A Systematic Review and Meta-Analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Using Medical Big Data to Develop Personalized Medicine for Dry Eye Disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LAVENDER: latent axes discovery from multiple cytometry samples with non-parametric divergence estimation and multidimensional scaling reconstruction2019

Author(s)

Journal Title

Nakamura Masahiro 中村正裕