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OSABE MAKOTO  長部 誠

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… Alternative Names

長部 誠  オサベ マコト

Osabe Makoto  長部 誠

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Researcher Number 40700985
Other IDs
Affiliation (Current) 2025: 日本薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 日本薬科大学, 薬学部, 講師
2018: 日本薬科大学, 薬学部, 講師
2017: 名古屋市立大学, 大学院薬学研究科, 助教
Review Section/Research Field
Principal Investigator
Medical pharmacy
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related
Keywords
Principal Investigator
免疫学 / 遺伝子 / 重症薬疹 / ゲノム / 皮膚障害 / 遺伝子多型 / タイピング / モガムリズマブ / ナノ粒子 / 限界希釈 / 遺伝子診断 / HLA … More
Except Principal Investigator
… More 薬物相互作用 / 生活習慣病 / 薬物代謝 / 非アルコール性脂肪性肝疾患 / シトクロムP450 Less
  • Research Projects

    (2 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (3 People)
  •  Changes in expression/activity of Cytochrome P450 in simple fatty liver and steatohepatitis

    • Principal Investigator
      Uramaru Naoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nihon Pharmaceutical University
  •  Development of HLA typing method to avoid the risk of severe cutaneous adverse drug reactionsPrincipal Investigator

    • Principal Investigator
      Osabe Makoto
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nihon Pharmaceutical University
      Nagoya City University

All 2024 2023 2022 2019 2018

All Journal Article Presentation

  • [Journal Article] Differential expression of Cytochrome P450 1A2 in simple fatty liver and steatohepatitis2023

    • Author(s)
      Kawashima Azusa、Uramaru Naoto、Mikuma Toshiyasu、Osabe Makoto、Higuchi Toshiyuki
    • Journal Title

      Fundamental Toxicological Sciences

      Volume: 10 Issue: 6 Pages: 265-277

    • DOI

      10.2131/fts.10.265

    • ISSN
      2189-115X
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Journal Article] Rhododendrol, a reductive metabolite of raspberry ketone, suppresses the differentiation of 3T3-L1 cells into adipocytes.2023

    • Author(s)
      Uramaru N, Kawashima A, Osabe M, Higuchi T.
    • Journal Title

      Mol Med Rep.

      Volume: 27(2) Issue: 2 Pages: 51-51

    • DOI

      10.3892/mmr.2023.12938

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Journal Article] Allopurinol suppresses expression of the regulatory T-cell migration factors TARC/CCL17 and MDC/CCL22 in HaCaT keratinocytes via restriction of nuclear factor-κB activation2018

    • Author(s)
      Osabe Makoto、Tajika Toshiyuki、Tohkin Masahiro
    • Journal Title

      Journal of Applied Toxicology

      Volume: 38 Issue: 2 Pages: 274-283

    • DOI

      10.1002/jat.3522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15517
  • [Presentation] 単純性脂肪肝および脂肪肝炎におけるシトクロムP450 1A2 発現/活性の反転変動2024

    • Author(s)
      川嶋梓、浦丸直人、三熊敏靖、長部誠、樋口敏幸
    • Organizer
      第144年会日本薬学会
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Presentation] ロドデノールは3T3-L1細胞の脂肪細胞への分化を抑制する2023

    • Author(s)
      浦丸直人、川嶋梓、長部誠、樋口敏幸
    • Organizer
      フォーラム2023衛生薬学・環境トキシコロジー
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Presentation] Rhododendrol, a reductive metabolite of raspberry ketone, suppresses the differentiation of 3T3-L1 cells into adipocytes.2023

    • Author(s)
      Uramaru N., Kawashima A., Osabe M., and Higuchi T.
    • Organizer
      The International Conference for Public Health, Environment, and Education for Sustainable Development Goals and Lifelong Learning
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Presentation] ロドデノールの3T3-L1前駆脂肪細胞における脂肪蓄積および脂肪細胞分化制御因子発現に対する抑制作用2022

    • Author(s)
      浦丸直人、川嶋梓、長部誠、樋口敏幸
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Presentation] NAFLからNASHへの進展過程におけるシトクロム P450分子種発現変動2022

    • Author(s)
      川嶋(片桐)梓、浦丸直人、長部誠、樋口敏幸
    • Organizer
      フォーラム2022:衛生薬学・環境トキシコロジー
    • Data Source
      KAKENHI-PROJECT-21K11599
  • [Presentation] HLA-B*58:01を介したオキシプリノールによる特異体質性副作用in vitro評価系の構築2019

    • Author(s)
      槇野隆太,長部誠,頭金正博
    • Organizer
      第1回医薬品毒性機序研究会,1月(名古屋)
    • Data Source
      KAKENHI-PROJECT-17K15517
  • [Presentation] LapatinibによるT細胞分化誘導機構の解析2019

    • Author(s)
      宮路康平,岡本秀人,槇野隆太,長部誠,頭金正博
    • Organizer
      第1回医薬品毒性機序研究会,1月(名古屋)
    • Data Source
      KAKENHI-PROJECT-17K15517
  • [Presentation] CLC Genomics Workbenchを用いたHLAタイピング法と他のタイピングソフトとの比較2018

    • Author(s)
      中嶋琢人,亀位涼,坂部彩,岡本秀人,長部誠,頭金正博
    • Organizer
      第4回次世代を担う若手のためのレギュラトリーサイエンスフォーラム,9月(東京)
    • Data Source
      KAKENHI-PROJECT-17K15517
  • [Presentation] The effect of lapatinib on lymphocyte activation and transcription factors in T cell differentiation2018

    • Author(s)
      Makino R., Okamoto H., Osabe M., Tohkin M.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology, July (Kyoto)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15517
  • 1.  Uramaru Naoto (90424069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  樋口 敏幸 (50264289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  村橋 毅 (70340445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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