FUKUSHIMA ARATA 福島新

Researcher Number	40706553
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 北海道大学, 大学病院, 医員 2019 – 2020: 北海道大学, 医学研究院, 客員研究員 2017 – 2018: 北海道大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator ミトコンドリア機能 / エネルギー代謝 / 心肥大 / 解糖系代謝 / 心筋脂肪酸代謝 / アセチル化修飾 / 脂肪酸代謝 / アセチル化 / 心不全 / 翻訳後修飾 / 心筋代謝 / 先天性心疾患 … More Except Principal Investigator … More ミトコンドリア / 骨格筋 / マイオカイン / 脳由来神経栄養因子 / 小腸パネート細胞 / 腸内フローラ / 心不全 / 小腸 / 腸内細菌 / αディフェンシン Less

Role of alpha-defensins derived from the small intestine and gut microbiota in heart failure
- Principal Investigator
  
  Yokota Takashi
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hokkaido University
Study on the mechanism of regulation of mitochondrial function by brain-derived neurotrophic factor
- Principal Investigator
  
  Kinugawa Shintaro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyushu University
  Hokkaido University
The role of protein lysine-acetlation in congenital heart diseasePrincipal Investigator
- Principal Investigator
  
  FUKUSHIMA ARATA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Hokkaido University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Brain-derived neurotrophic factor improves impaired fatty acid oxidation via the activation of AMPKα-PGC1α signaling in skeletal muscle of mice with heart failure2021
- Author(s)
  125.Matsumoto J, Takada S, Furihata T, Nambu H, Kakutani N, Maekawa S, Mizushima W, Nakano I, Fukushima A, Yokota T, Tanaka S, Handa H, Sabe H, Kinugawa S
- Journal Title
  
  Circ Heart Fail
  
  Volume: １４
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03187
[Journal Article] Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance2021
- Author(s)
  124.Nambu H, Takada S, Maekawa S, Matsumoto J, Kakutani N, Furihata T, Shirakawa R, Katayama T, Nakajima T, Yamanashi K, Obata Y, Nakano I, Tsuda M, Saito A, Fukushima A, Yokota T, Nio-Kobayashi J, Yasui H, Higashikawa K, Kuge Y, Anzai T, Sabe H, Kinugawa S
- Journal Title
  
  Cardiovasc Res
  
  Volume: 117 Pages: 805-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03187
[Journal Article] Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure2021
- Author(s)
  126.Furihata T, Takada S, Kakutani N, Maekawa S, Tsuda M, Matsumoto J, Mizushima W, Fukushima A, Yokota T, Enzan N, Matsushima S, Handa H, Fumoto Y, Nio-Kobayashi J, Iwanaga T, Tanaka S, Tsutsui H, Sabe H, Kinugawa S
- Journal Title
  
  Commun Biol
  
  Volume: 4 Pages: 138-138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03187
[Journal Article] Branched-chain amino acid supplementation ameliorates angiotensin II-induced skeletal muscle atrophy.2020
- Author(s)
  Yamanashi K, Kinugawa S, Fukushima A, Kakutani N, Takada S, Obata Y, Nakano I, Yokota T, Kitaura Y, Shimomura Y, Anzai T.
- Journal Title
  
  Life Sciences
  
  Volume: 250 Pages: 117593-117595
- DOI
  10.1016/j.lfs.2020.117593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10137, KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-17H04758
[Journal Article] Angiotensin-converting-enzym inhibitor prevents skeletal uscle fibrosis in myocardial infarction mice2020
- Author(s)
  121.Yamanashi K, Kinugawa S, Fukushima A, Kakutani N, Takada S, Obata Y, Nakano I, Yokota T, Kitaura Y, Shimomura Y, Anzai T
- Journal Title
  
  Life Sciences
  
  Volume: 250 Pages: 117593-117593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03187
[Journal Article] Angiotensin-converting-enzym inhibitor prevents skeletal uscle fibrosis in myocardial infarction mice2020
- Author(s)
  122.Kakutani N, Takada S, Nambu H, Matsumoto J, Furihata T, Yokota T, Fukushima A, Kinugawa S
- Journal Title
  
  Skelet Muscle
  
  Volume: 10 Pages: 11-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03187
[Journal Article] Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients2019
- Author(s)
  Shirakawa Ryosuke、Yokota Takashi、Nakajima Takayuki、Takada Shingo、Yamane Miwako、Furihata Takaaki、Maekawa Satoshi、Nambu Hideo、Katayama Takashi、Fukushima Arata、Saito Akimichi、Ishimori Naoki、Dela Flemming、Kinugawa Shintaro、Anzai Toshihisa
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 14709-14709
- DOI
  10.1038/s41598-019-51298-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-18K15834, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-17H04758
[Journal Article] Enhanced Echo Intensity of Skeletal Muscle Is Associated With Exercise Intolerance in Patients With Heart Failure2019
- Author(s)
  Nakano Ippei、Hori Hiroaki、Fukushima Arata、Yokota Takashi、Kinugawa Shintaro、Takada Shingo、Yamanashi Katsuma、Obata Yoshikuni、Kitaura Yasuyuki、Kakutani Naoya、Abe Takahiro、Anzai Toshihisa
- Journal Title
  
  Journal of Cardiac Failure
  
  Volume: - Issue: 8 Pages: 30416-30419
- DOI
  10.1016/j.cardfail.2019.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-17K10137, KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-17H04758
[Journal Article] Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis.2019
- Author(s)
  Nakajima T, Yokota T, Shingu Y, Yamada A, Iba Y, Ujihira K, Wakasa S, Ooka T, Takada S, Shirakawa R, Katayama T, Furihata T, Fukushima A, Matsuoka R, Nishihara H, Dela F, Nakanishi K, Matsui Y, Kinugawa S.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 3535-3535
- DOI
  10.1038/s41598-019-40419-7
- NAID
  120006603703
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04758, KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-18H03187
[Journal Article] A mitochondrial delivery system using liposome-based nanocarriers that target myoblast cells2019
- Author(s)
  Katayama Takashi、Kinugawa Shintaro、Takada Shingo、Furihata Takaaki、Fukushima Arata、Yokota Takashi、Anzai Toshihisa、Hibino Mitsue、Harashima Hideyoshi、Yamada Yuma
- Journal Title
  
  Mitochondrion
  
  Volume: 49 Pages: 66-72
- DOI
  10.1016/j.mito.2019.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-17H02094, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-17H04758
[Journal Article] Acetylation contributes to hypertrophy-caused maturational delay of cardiac energy metabolism.2018
- Author(s)
  Fukushima A, Zhang L, Huqi A, Lam VH, Rawat S, Altamimi T, Wagg CS, Dhaliwal KK, Hornberger LK, Kantor PF, Rebeyka IM, Lopaschuk GD.
- Journal Title
  
  JCI Insight
  
  Volume: 3(10) Issue: 10 Pages: 99239-99256
- DOI
  10.1172/jci.insight.99239
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10137
[Journal Article] Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure2018
- Author(s)
  Tsuda Masaya、Fukushima Arata、Matsumoto Junichi、Takada Shingo、Kakutani Naoya、Nambu Hideo、Yamanashi Katsuma、Furihata Takaaki、Yokota Takashi、Okita Koichi、Kinugawa Shintaro、Anzai Toshihisa
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle
  
  Volume: 9 Issue: 5 Pages: 844-859
- DOI
  10.1002/jcsm.12322
- NAID
  120006626588
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-17H04758
[Journal Article] Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure2018
- Author(s)
  Matsumoto Junichi、et al. Hatakeyama Shigetsugu、Matsumoto Masaki、Nakayama Keiichi I.、Otsuka Yutaro、Sabe Hisataka、Tsutsui Hiroyuki、Anzai Toshihisa
- Journal Title
  
  Circulation
  
  Volume: 138 Issue: 18 Pages: 2064-2066
- DOI
  10.1161/circulationaha.118.035212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17H04758, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Presentation] Increased echo intensity of skeletal muscle is associated with exercise intolerance in patients with heart failure2019
- Author(s)
  Nakano I, Hori H, Fukushima A, Yokota T, Kinugawa S, Takada S, Yamanashi K, Obata Y, Kitaura Y, Kakutani N, Abe T, Anzai T
- Organizer
  Euro Prevent 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03187
[Presentation] Administration of brain-derived neurotrophic factor improves the lowered exercise capacity and mitochondrial function in the skeletal muscle of mice with post-infarct heart failure.2018
- Author(s)
  Takada S, Matsumoto J, Kinugawa S, Furihata T, Nambu H, Kakutani N, Maekawa S, Shirakawa R, Katayama T, Yamanashi K, Obata Y, Saito A, Fukushima A, Yokota T, Okita K, Anzai T
- Organizer
  American Heart Association Scientific Session 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03187
[Presentation] Brain-derived neurotrophic factor improves limited exercise capacity by regulating mitochondrial faty-acid oxidation in mice with heart failure2018
- Author(s)
  Matsumoto J, Takada S, Kinugawa S, Furihata T, Nambu H, Kakutani N, Fukushima A, Yokota T, Tsutsui H, Anzai T
- Organizer
  第22回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03187
[Presentation] Protein acetylation in skeletal muscle impairs mitochondrial fatty acid oxidation and limits exercise capacity in post-infarct heart failure in mice.2017
- Author(s)
  山梨克真，津田正哉，福島　新，高田真吾，降旗高明，松本純一，前川　聡，片山貴史，横田　卓，絹川真太郎
- Organizer
  第21回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10137
[Presentation] Mitochondrial Protein Hyperacetylation in Skeletal Muscle is Associated with Exercise Intolerance in Murine Model of Post-Infarct Heart Failure2017
- Author(s)
  Fukushima A, Tsuda M, Takada S, Yokota T, Saito A, Mizushima W, Furihata T, Matsumoto J, Katayama T, Nakajima T, Maekawa S, Nambu H, Shirakawa R, Kakutani N, Yoshikuni O, Yamanashi K, Okita K, and Kinugawa S
- Organizer
  22nd International Academy of Cardiology Annual Scientific Sessions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10137
[Presentation] Cardiac hypertrophy in congenital heart disease delays the maturation of cardiac fatty acid β-oxidation by modifying myocardial acetylation control2017
- Author(s)
  Fukushima A, Kingawa S, Yokota T, Takada S, Furihata T, Matsumoto J, Tsuda M, Nakajima T, Katayama T, Nanbu H, Maekawa S, Kakutani N, Shirakawa R, Okita K, Kantor PF, Rebeyka, IM, Lopaschuk GD
- Organizer
  第81回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10137
[Presentation] Acetylation of mitochondrial proteins alters fatty acid β-oxidation in skeletal muscle and limits exercise capacity in post-infarct heart failure in mice.2017
- Author(s)
  Masaya T, Fukushima A, Matsumoto J, Takada S, Yokota T, Furihata T, Katayama T, Nakajima T, Nambu H, Maekawa S, Shirakawa R, Kakutani N, Obata Y, Yamanashi K, Okita K, Kinugawa S
- Organizer
  American Heart Association Scientific Session
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10137

1. Kinugawa Shintaro (60399871)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. Yokota Takashi (90374321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. 高田真吾 (60722329)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
4. 安斉俊久 (60232089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 綾部時芳 (90301019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUKUSHIMA ARATA 福島 新

Research Projects

Research Products

Co-Researchers

Role of alpha-defensins derived from the small intestine and gut microbiota in heart failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the mechanism of regulation of mitochondrial function by brain-derived neurotrophic factor

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of protein lysine-acetlation in congenital heart diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Brain-derived neurotrophic factor improves impaired fatty acid oxidation via the activation of AMPKα-PGC1α signaling in skeletal muscle of mice with heart failure2021

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance2021

Author(s)

Journal Title

Data Source

[Journal Article] Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure2021

Author(s)

Journal Title

Data Source

[Journal Article] Branched-chain amino acid supplementation ameliorates angiotensin II-induced skeletal muscle atrophy.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Angiotensin-converting-enzym inhibitor prevents skeletal uscle fibrosis in myocardial infarction mice2020

Author(s)

Journal Title

Data Source

[Journal Article] Angiotensin-converting-enzym inhibitor prevents skeletal uscle fibrosis in myocardial infarction mice2020

Author(s)

Journal Title

Data Source

[Journal Article] Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced Echo Intensity of Skeletal Muscle Is Associated With Exercise Intolerance in Patients With Heart Failure2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A mitochondrial delivery system using liposome-based nanocarriers that target myoblast cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetylation contributes to hypertrophy-caused maturational delay of cardiac energy metabolism.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure2018

FUKUSHIMA ARATA 福島新