Taguchi Akihiro 田口晃弘

… Alternative Names

TAGUCHI Akihiro 田口晃弘

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Researcher Number	40707311
Other IDs
Affiliation (Current)	2022: 東京薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2022: 東京薬科大学, 薬学部, 講師 2016 – 2019: 東京薬科大学, 薬学部, 助教 2013 – 2014: 東京薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator 創薬化学 / ジスルフィド結合 / ペプチド合成 / 固相合成 / 有機化学 / 3-ニトロ-2-ピリジンスルフェニル / リードスルー / ネガマイシン / デュシェンヌ型筋ジストロフィー / 抗生物質 … More / 固相担持試薬 / 3-ニトロ-2-ピリジンスルフェニル基 / ペプチド合成化学 / ジスルフィド / 環状ペプチド / 3-ニトロ-2-ピリジンスルフェン酸エステル / ペプチド / トリプトファン / ペプチド修飾 / タンパク質修飾 … More Except Principal Investigator 固相ジスルフィドライゲーション / 中分子ペプチド / ペプチドー薬物架橋体 / 創薬 / ケミカルバイオロジー / 固相ジスルフィドライゲーション / ペプチド－薬物架橋体 Less

Npys化学を基盤としたトリプトファン残基選択的修飾法の開発と生体分子への応用Principal Investigator
- Principal Investigator
  
  田口晃弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of disulfide-driven cyclic peptide synthesis based on Npys derivativesPrincipal Investigator
- Principal Investigator
  
  Taguchi Akihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Synthesis and Medicinal Chemical Development of Mid-Sized Peptide Conjugate Based on the Chemistry of Solid-Phase Disulfide Ligation
- Principal Investigator
  
  林良雄
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of thiol-selective disulfide forming reagent for the application to peptide chemistryPrincipal Investigator
- Principal Investigator
  
  Taguchi Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Study of medicinal chemistry of nonsense mutation disease therapeutics focused on negamycin with readthrough activityPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Akihiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2022 2021 2020 2019 2018 2017 2016 2014 2013 Other

All Journal Article Presentation Book Patent

[Book] ファルマシア2014
- Author(s)
  田口晃弘、濵田圭佑、林　良雄
- Total Pages
  5
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-25893258
[Journal Article] Development of Myostatin Inhibitory D-Peptides to Enhance the Potency Increasing Skeletal Muscle Mass in Mice2022
- Author(s)
  Takayama Kentaro、Hitachi Keisuke、Okamoto Hideyuki、Saitoh Mariko、Odagiri Miki、Ohfusa Rina、Shimada Takahiro、Taguchi Akihiro、Taniguchi Atsuhiko、Tsuchida Kunihiro、Hayashi Yoshio
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 13 Pages: 492-498
- DOI
  10.1021/acsmedchemlett.1c00705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-20K07315
[Journal Article] Structural revision of natural cyclic depsipeptide MA026 established by total synthesis and biosynthetic gene cluster analysis2021
- Author(s)
  Uchiyama Chihiro、Fukuda Akane、Mukaiyama Minagi、Nakazawa Yoshiki、Kuramochi Yuka、Muguruma Kyohei、Arimoto Mitsue、Ninomiya Akihiro、Kako Koichiro、Katsuyama Yohei、Konno Sho、Taguchi Akihiro、Takayama Kentaro、Taniguchi Atsuhiko、Nagumo Yoko、Usui Takeo、Hayashi Yoshio
- Journal Title
  
  Angewandte Chemie (International ed. in English)
  
  Volume: 60 Pages: 8792-8797
- DOI
  10.1002/anie.202015193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H02893, KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-17K01942
[Journal Article] Development of a high‐affinity antibody‐binding peptide for site‐specific modification.2021
- Author(s)
  Muguruma, K., Osawa, R., Fukuda, A., Ishikawa, N., Fujita, K., Taguchi, A., Takayama, K., Taniguchi, A., Ito, Y., Hayashi, Y.
- Journal Title
  
  ChemMedChem
  
  Volume: 16 Pages: 1-9
- DOI
  10.1002/cmdc.202000977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03356
[Journal Article] Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation2021
- Author(s)
  Okamoto Hideyuki、Taniguchi Atsuhiko、Usami Shoya、Katsuyama Masahiro、Konno Sho、Taguchi Akihiro、Takayama Kentaro、Hayashi Yoshio
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 19 Pages: 199-207
- DOI
  10.1039/d0ob02042g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356
[Journal Article] Proposal for the Binding Mode of the 23-Mer Inhibitory Peptide to Myostatin2021
- Author(s)
  Asari Tomo、Ikeyama Hiroaki、Taguchi Akihiro、Taniguchi Atsuhiko、Hayashi Yoshio、Takayama Kentaro
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 40 Pages: 116181-116181
- DOI
  10.1016/j.bmc.2021.116181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19H03356
[Journal Article] “On-Resin” disulfide peptide synthesis with methyl 3-nitro-2-pyridinesulfenate2021
- Author(s)
  Kobayashi Kiyotaka、Taguchi Akihiro、Cui Yan、Shida Hayate、Muguruma Kyohei、Takayama Kentaro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 2021 Pages: 956-963
- DOI
  10.1002/ejoc.202001517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K16324, KAKENHI-PROJECT-19H03356
[Journal Article] Use of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate in the construction of disulfide- linked hybrid molecules2020
- Author(s)
  Cui Yan、Taguchi Akihiro、Kobayashi Kiyotaka、Shida Hayate、Takayama Kentaro、Taniguchi Atsuhiko、Hayashi Yoshio
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 18 Pages: 7094-7097
- DOI
  10.1039/d0ob01370f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K16324, KAKENHI-PROJECT-19H03356
[Journal Article] Disulfide-Driven Cyclic Peptide Synthesis of Human Endothelin-2 with a Solid-Supported Npys-Cl2020
- Author(s)
  Akihiro Taguchi, Kiyotaka Kobayashi, Yan Cui, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 85 Pages: 1495-1503
- DOI
  10.1021/acs.joc.9b02362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-19K07001
[Journal Article] New negamycin-based potent readthrough derivative effective against TGA-type nonsense mutations2019
- Author(s)
  Keisuke Hamada, Noriko Omura, Akihiro Taguchi, Alireza Baradaran-Heravi, Masaya Kotake, Misaki Arai, Kentaro Takayama, Atsuhiko Taniguchi, Michel Roberge, Yoshio Hayashi
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 10 Pages: 1450-1456
- DOI
  10.1021/acsmedchemlett.9b00273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03356
[Journal Article] Synthesis and structure-activity relationship studies of IgG-binding peptides focused on the C-terminal histidine residue2019
- Author(s)
  Kyohei Muguruma, Mayu Ito, Akane Fukuda, Satoshi Kishimoto, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yuji Ito and Yoshio Hayashi
- Journal Title
  
  Med. Chem. Commun.
  
  Volume: 10 Pages: 1789-1795
- DOI
  10.1039/c9md00294d
- Data Source
  KAKENHI-PROJECT-19H03356
[Journal Article] Kinetics-Based Structural Requirements of Human Immunoglobulin G Binding Peptides2019
- Author(s)
  Kyohei Muguruma, Konomi Fujita, Akane Fukuda, Satoshi Kishimoto, Soichiro Sakamoto, Risako Arima, Mayu Ito, Mayu Kawasaki, Shogo Nakano, Sohei Ito, Kanade Shimizu, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yuji Ito, Yoshio Hayashi
- Journal Title
  
  ACS Omega
  
  Volume: 4 Pages: 14390-14397
- DOI
  10.1021/acsomega.9b01104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03356, KAKENHI-PROJECT-18K14391
[Journal Article] 4-Fluorophenyl 3-nitro-2-pyridinesulfenate as a practical protecting agent for amino acids2018
- Author(s)
  Yan Cui, Cedric Rentier, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 24
- DOI
  10.1002/psc.3070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18914, KAKENHI-PROJECT-17K13260
[Journal Article] 3-Nitro-2-pyridinesulfenates as Efficient Solution- and Solid-Phase Disulfide Bond Forming Agents2017
- Author(s)
  Akihiro Taguchi, Kiyotaka Kobayashi, Akira Kotani, Kyohei Muguruma, Misaki Kobayashi, Kentarou Fukumoto, Kentaro Takayama, Hideki Hakamata, Yoshio Hayashi
- Journal Title
  
  Chemistry-A European Journal
  
  Volume: 23 Pages: 8262-8267
- DOI
  10.1002/chem.201700952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18914
[Journal Article] Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3-epi-Deoxynegamycin and Its Leucine Adduct2014
- Author(s)
  Akihiro Taguchi, Keisuke Hamada, Masaya Kotake, Masataka Shiozuka, Hidemasa Nakaminami, Thanigaimalai Pillaiyar, Kentaro Takayama, Fumika Yakushiji, Norihisa Noguchi, Takeo Usui, Ryoichi Matsuda, Yoshio Hayashi
- Journal Title
  
  ChemMedChem
  
  Volume: 9 Pages: 2233-2237
- DOI
  10.1002/cmdc.201402208
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25893258, KAKENHI-PUBLICLY-26102740
[Patent] ネガマイシン誘導体2021
- Inventor(s)
  林良雄、田口晃弘ら
- Industrial Property Rights Holder
  東京薬科大学など
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03356
[Patent] Selective Disulfidation Reagent Using Nitrogen-Containing Compound and Method for Producing Disulfide-Containing Compound2017
- Inventor(s)
  林　良雄、田口　晃弘、福元　謙太郎
- Industrial Property Rights Holder
  林　良雄、田口　晃弘、福元　謙太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-16K18914
[Patent] 含窒素化合物を用いた選択的ジスルフィド化試薬、およびジスルフィド含有化合物の製造方法2016
- Inventor(s)
  林　良雄、田口晃弘、福元謙太郎
- Industrial Property Rights Holder
  林　良雄、田口晃弘、福元謙太郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-101812
- Filing Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of new one-pot synthetic method for cyclic disulfide peptides based on 3-nitro-2-pyridinesulfenates2021
- Author(s)
  H. Shida, A. Taguchi, K. Kobayashi, Y. Cui, S. Konno, K. Takayama, A. Taniguchi, Y. Hayashi
- Organizer
  13th AFMC International Medicinal Chemistry Symposium (AIMECS2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] ニトロピリジンスルフェン酸エステルを用いた環状ペプチド固相合成法の開発2021
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、今野翔、髙山健太郎、谷口敦彦、林良雄
- Organizer
  創薬懇話会2021 in 京都
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of solid supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate for the efficient construction of disulfide-linked hybrid molecules2021
- Author(s)
  崔岩、田口晃弘、小林清孝、志田颯、今野翔、谷口敦彦、高山健太郎、林良雄
- Organizer
  創薬懇話会2021 in 京都
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] One-pot Disulfide-driven Cyclic Peptide Synthesis of Oxytocin Using 4-Fluorophenyl 3-Nitro-2-pyridinesulfenate (Npys-OPh(pF))2021
- Author(s)
  H. Shida, A. Taguchi, K. Kobayashi, Y. Cui, S. Konno, K. Takayama, A. Taniguchi, Y. Hayashi
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 固相Npys化反応を鍵とするジスルフィド駆動型環状ペプチド合成法の開発2021
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、今野翔、髙山健太郎、谷口敦彦、林良雄
- Organizer
  第47回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 分子空間固定型ネガマイシンの合成とそのリードスルー活性評価2021
- Author(s)
  大村紀子、田口晃弘、濵田圭佑、桑原智希、渡邉瑞貴、中久木正則、今野翔、高山健太郎、谷口敦彦、乃村俊史、周東智、林良雄
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] One-pot Disulfide-driven Cyclic Peptide Synthesis of Oxytocin Using 4-Fluorophenyl 3-Nitro-2-pyridinesulfenate (Npys-OPh(pF))2021
- Author(s)
  Hayate Shida, Akihiro Taguchi, Kiyotaka Kobayashi, Yan Cui, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] Structure-Activity Relationship Study Focusing on 3-epi-Deoxynegamycin for Readthrough Activity2021
- Author(s)
  N. Omura, A. Taguchi, K. Hamada, T. Kuwahara, M. Watanabe, M. Nakakuki, S. Konno, K. Takayama, A. Taniguchi, T. Nomura, S. Shuto, Y. Hayashi
- Organizer
  13th AFMC International Medicinal Chemistry Symposium (AIMECS2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 固相Npys化反応を鍵とするジスルフィド駆動型環状ペプチド合成法の開発2021
- Author(s)
  志田　颯、田口　晃弘、小林　清孝、崔　岩、今野　翔、髙山　健太郎、谷口　敦彦、林　良雄
- Organizer
  第47回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity (Excellent Poster Presentation Award)2021
- Author(s)
  N. Omura, A. Taguchi, K. Hamada, T. Kuwahara, M. Watanabe, M. Nakakuki, S. Konno, K. Takayama, A. Taniguchi, T. Nomura, S. Shuto, Y. Hayashi
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of new one-pot synthetic method for cyclic disulfide peptides based on 3-nitro-2-pyridinesulfenates2021
- Author(s)
  Hayate Shida, Akihiro Taguchi, Kiyotaka Kobayashi, Yan Cui, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  13th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] Development of One-pot Synthesis of Cyclic Disulfide Peptide Using Water-soluble Npys Derivative2021
- Author(s)
  M. Sakata, A. Taguchi, S. Kuraishi, S. Konno, K. Takayama, A. Taniguchi, Y. Hayashi
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 高活性リードスルー化合物の獲得を目指したネガマイシン誘導体５位アミノ基の誘導化2021
- Author(s)
  澤田直志、大村紀子、濵田圭佑、今野翔、田口晃弘、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 光酸素化能を付与した機能化ペプチドによるマイオスタチンの活性阻害2021
- Author(s)
  岡本英之、谷口敦彦、宇佐美翔哉、勝山雅大、今野翔、田口晃弘、高山健太郎、林良雄
- Organizer
  創薬懇話会2021 in 京都
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 水溶性Npys誘導体を用いたジスルフィドペプチドの効率的合成法開発2021
- Author(s)
  坂田萌、田口晃弘、倉石彩恵香、今野翔、髙山健太郎、谷口敦彦、林良雄
- Organizer
  創薬懇話会2021 in 京都
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 水溶性Npys誘導体の機能評価：アドレノメジュリンのワンポット合成2021
- Author(s)
  坂田萌、田口晃弘、倉石彩恵香、今野翔、髙山健太郎、谷口敦彦、林良雄
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Efficient Inhibition of Myostatin Activity by Functionalized Peptides with Photooxygenation Catalyst2021
- Author(s)
  H. Okamoto, A. Taniguchi, S. Usami, M. Katsuyama, S. Konno, A. Taguchi, K. Takayama, Y. Hayashi
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Modular synthesis of HIV-1 protease analogue by disulfide ligation using 4-fluorophenyl 3-nitro-2-pyridinesulfenate (Npys-OPh(pF))2021
- Author(s)
  Y. Cui, A. Taguchi, H. Shida, K. Kobayashi, S. Konno, K. Takayama, A. Taniguchi, Y. Hayashi
- Organizer
  13th AFMC International Medicinal Chemistry Symposium (AIMECS2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Modular synthesis of disulfide cross-linked HIV-1 protease analogue using 4-fluorophenyl 3-nitro-2-pyridinesulfenate (Npys-OPh(pF))2021
- Author(s)
  Y. Cui, A. Taguchi, H. Shida, K. Kobayashi, S. Konno, K. Takayama, A. Taniguchi, Y. Hayashi
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of New Peptide Synthetic Methodology Based on 3-Nitro-2-Pyridinesulfenyl (Npys) Chemistry2021
- Author(s)
  A. Taguchi
- Organizer
  24th Korean Peptide and Protein Society Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of peptide-photooxygenation catalyst conjugates that efficiently oxygenate myostatin2021
- Author(s)
  H. Okamoto, A. Taniguchi, S. Usami, M. Katsuyama, S. Konno, A. Taguchi, K. Takayama, Y. Hayashi
- Organizer
  13th AFMC International Medicinal Chemistry Symposium (AIMECS2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] ニトロピリジンスルフェン酸エステルを用いた環状ペプチド固相合成法の開発2021
- Author(s)
  志田　颯、田口　晃弘、小林　清孝、崔　岩、今野　翔、髙山　健太郎、谷口　敦彦、林　良雄
- Organizer
  創薬懇話会2021 in 京都
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] ネガマイシン３位アミノ基誘導体の創製と各種遺伝性疾患に対するリードスルー効果の検討2021
- Author(s)
  大村紀子、濵田圭佑、田口晃弘、今野翔、高山健太郎、谷口敦彦、林良雄
- Organizer
  創薬懇話会2021 in 京都
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 標的選択的光酸素化を用いたマイオスタチンの効率的阻害2021
- Author(s)
  谷口敦彦、岡本英之、宇佐美翔哉、勝山雅大、今野翔、田口晃弘、高山健太郎、林良雄
- Organizer
  日本ケミカルバイオロジー学会第15回年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] マイオスタチンを選択的に光酸素化する短鎖化ペプチドー触媒架橋体の開発2021
- Author(s)
  村野周子アンバー、岡本英之、勝山雅大、今野翔、田口晃弘、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 部位特異的抗体修飾法に応用可能な高親和性抗体結合ペプチドの創製2021
- Author(s)
  大澤錬人、六車共平、福田茜、藤田好珠、石川直到、田口晃弘、高山健太郎、谷口敦彦、伊東祐二、林良雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 水溶性Npys誘導体を用いた環状ジスルフィドペプチドのワンポット合成2021
- Author(s)
  坂田萌、田口晃弘、倉石彩恵香、今野翔、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 固相法を基盤とした新規環状ジスルフィドペプチド合成法の開発2020
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、髙山健太郎、谷口敦彦、林良雄
- Organizer
  第64回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 固相ワンポットジスルフィド駆動型環状ペプチド合成法の開発2020
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] 固相法を基盤とした新規環状ジスルフィドペプチド合成法の開発2020
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、髙山健太郎、谷口敦彦、林良雄
- Organizer
  第64回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] Development of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate (Npys-OPh(pF)) as an efficient disulfide-forming agent2020
- Author(s)
  Y. Cui, A. Taguchi, K. Kobayashi, H. Shida, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] Development of new peptide synthetic methodology based on disulfide bond formation: revival of Npys chemistry2020
- Author(s)
  A. Taguchi
- Organizer
  第57回　ペプチド討論会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of Solid-Supported 4-Fluorophenyl 3-Nitro-2-Pyridinesulfenate (Npys-OPh(pF)) as An Efficient Disulfide-Forming Agent2020
- Author(s)
  Y. Cui, A. Taguchi, K. Kobayashi, H. Shida, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  第57回　ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of Solid Supported Npys-OPh(pF) Agent for Efficient Solid-Phase Disulfide Ligation2020
- Author(s)
  Y. Cui, A. Taguchi, K. Kobayashi, H. Shida, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  The 16th Chinese International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 固相ワンポットジスルフィド駆動型環状ペプチド合成法の開発2020
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] NPYS化学を基盤とするペプチド合成化学から創薬までの研究展開2019
- Author(s)
  林良雄、田口晃弘、六車共平、Yan Cui、小林清孝
- Organizer
  第63回　日本薬学会　関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] タイトジャンクション開口剤MA026の構造訂正及び構造活性相関研究2019
- Author(s)
  内山千尋、福田茜、向山海凪、中澤佳輝、有本光江、加香考一郎、田口晃弘、高山健太郎、谷口敦彦、南雲陽子、臼井健郎、林良雄
- Organizer
  第63回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Structure revision of cyclic depsipeptide MA026 and structure-activity relationship study based on tight junction open activity2019
- Author(s)
  内山千尋、福田茜、向山海凪、中澤佳輝、有本光江、加香考一郎、田口晃弘、高山健太郎、谷口敦彦、南雲陽子、臼井健郎、林良雄
- Organizer
  第56回　ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Structure-activity relationship study of an antibody-binding peptide for the preparation of antibody-drug conjugate2019
- Author(s)
  K. Muguruma, K. Fujita, A. Fukuda, S. Kishimoto, R. Arima, A. Taguchi, K. Takayama, A. Taniguchi, Y. Ito, and Y. Hayashi
- Organizer
  Antibody Engineering & Therapeutics 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 生体分子におけるジスルフィド結合形成を指向した水溶性Npys誘導体の創製2019
- Author(s)
  田口晃弘、倉石彩恵香、小林清孝、崔　岩、高山健太郎、谷口敦彦、林良雄
- Organizer
  日本ケミカルバイオロジー学会　第14回年会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Structure-Activity Relationship Study of Human IgG Binding Peptide Focused on Glycine Residue at the Position 92019
- Author(s)
  A. Fukuda, K. Muguruma, R. Osawa, S. Kishimoto, A. Taguchi, K.Takayama, A. Taniguchi, Y. Ito, and Y. Hayashi
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate agent for efficient solid-phase disulfide ligation2019
- Author(s)
  崔岩、田口晃弘、小林清孝、志田颯、高山健太郎、谷口敦彦、林良雄
- Organizer
  第63回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] 水溶性Npys 誘導体を基盤としたジスルフィド形成試薬の創製とその機能性評価2019
- Author(s)
  田口晃弘，倉石彩恵香，小林清孝，崔岩，高山健太郎，谷口敦彦，林良雄
- Organizer
  第45回　反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 水溶性Npys誘導体の創製とそのジスルフィド結合能評価2019
- Author(s)
  倉石　彩恵香、田口　晃弘、小林　清孝、崔　岩、高山　健太郎、谷口　敦彦、林　良雄
- Organizer
  日本薬学会第 139 年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF AN ANTIBODY- BINDING PEPTIDE FOCUSED ON GLYCINE RESIDUE AT THE POSITION 92019
- Author(s)
  A. Fukuda, K. Muguruma, R. Osawa, S. Kishimoto, A. Taguchi, K.Takayama, A. Taniguchi, Y. Ito, and Y. Hayashi
- Organizer
  第56回　ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] development of leucyl-3-epi-deoxynegamycin derivative with a potent readthrough activity2019
- Author(s)
  大村紀子、濵田圭佑、田口晃弘、嶋野慶樹、澤田直志、高山健太郎、谷口敦彦、林良雄
- Organizer
  第56回　ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] A new scenario for disulfide peptide synthesis based on 3-nitro-2-pyridinesulfenates2019
- Author(s)
  Y. Hayashi, A. Taguchi
- Organizer
  The 7th Modern Solid Phase Peptide Synthesis & Its Applications Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] SAR study of negamycin derivative focused on the 3-amino position for potent readthrough activity2019
- Author(s)
  N. Omura, K. Hamada, A. Taguchi, M. Arai, K. Shimano, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  26th American Peptide Symposium and 11th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] ジスルフィド駆動型環状ペプチド合成法によるヒトエンドセリン-2の合成2019
- Author(s)
  志田颯、田口晃弘、小林清孝、崔岩、高山健太郎、谷口敦彦、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 抗体-薬物複合体への応用をめざした微小管重合阻害剤Plinabulinのジスルフィド型プロドラッグ創製研究2019
- Author(s)
  佐藤菜那、福田茜、六車共平、黒田綾、遠藤京弥、田口晃弘、高山健太郎、谷口敦彦、伊東祐二、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Structure revision and structure-activity relationship as TJ opener of MA0262019
- Author(s)
  C. Uchiyama, A. Fukuda, M. Mukaiyama, D. Nakazawa, M. Arimoto, K. Kako, A. Taguchi, K. Takayama, A. Taniguchi, Y. Nagumo, T. Usui, and Y. Hayashi
- Organizer
  The 7th Modern Solid Phase Peptide Synthesis & Its Applications Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of 4-Fluorophenyl 3-Nitro-2-Pyridinesulfenate, Npys-OPh(pF) Resin as An Efficient Disulfide-Forming Reagent2019
- Author(s)
  Y. Cui, A. Taguchi, K. Kobayashi, H. Shida, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19K16324
[Presentation] 生体分子へ適用可能な水溶性Npys型ジスルフィド形成試薬の創製2019
- Author(s)
  濵田佳穂、田口晃弘、倉石彩恵香、小林清孝、崔岩、高山健太郎、谷口敦彦、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Npys-OMeを用いた固相ジスルフィド架橋法による環状ペプチドの合成展開(Synthesis of cyclic peptides by on-resin disulfide bond formation via Npys-OMe)2019
- Author(s)
  小林清孝、田口晃弘、崔岩、志田颯、濵田佳穂、高山健太郎、谷口敦彦、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate agent for efficient solid-phase disulfide ligation2019
- Author(s)
  崔岩、田口晃弘、小林清孝、志田颯、高山健太郎、谷口敦彦、林良雄
- Organizer
  第63回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of 4-Fluorophenyl 3-Nitro-2-Pyridinesulfenate, Npys-OPh(pF) Resin as An Efficient Disulfide-Forming Reagent2019
- Author(s)
  崔岩、田口晃弘、小林清孝、志田颯、高山健太郎、谷口敦彦、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] "ON-RESIN" disulfide peptide synthesis using methyl 3-nitro-2-pyridinesulfenate2019
- Author(s)
  K. Kobayashi, A. Taguchi, K. Muguruma, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  26th American Peptide Symposium and 11th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Synthesis and structure-activity relationship study of an antibody-binding peptide focused on the C-terminal histidine residue2019
- Author(s)
  M. Ito, K. Muguruma, A. Fukuda, S. Kishimoto, A. Taguchi, K. Takayama, A. Taniguchi, Y. Ito, and Y. Hayashi
- Organizer
  The 27th French-Jaanese Suymposium on Medicinal and Fine Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of water-soluble Npys-OMe derivatives for the disulfide bond formation of biomolecules2019
- Author(s)
  A. Taguchi, S. Kuraishi, K. Kobayashi, Y. Cui, K. Takayama, A. Taniguchi, and Y. Hayashi
- Organizer
  The 27th French-Jaanese Suymposium on Medicinal and Fine Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] MA026の構造訂正及びタイトジャンクション開口能に基づいた構造活性相関研究2019
- Author(s)
  内山千尋、福田茜、向山海凪、中澤佳輝、有本光江、加香考一郎、田口晃弘、高山健太郎、谷口敦彦、南雲陽子、臼井健郎、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] 高リードスルー活性を有するネガマイシン誘導体TCP-1109の創製とその活性評価2019
- Author(s)
  嶋野慶樹、濵田圭佑、大村紀子、田口晃弘、澤田直志、高山健太郎、谷口敦彦、林良雄
- Organizer
  第37回　メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Structure-antibody binding affinity relationship study of cyclic disulfide peptides2019
- Author(s)
  K. Muguruma, K. Fujita, A. Fukuda, S. Kishimoto, R. Arima, A. Taguchi, K. Takayama, A. Taniguchi, Y. Ito, and Y. Hayashi
- Organizer
  26th American Peptide Symposium and 11th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03356
[Presentation] Development of New Npys-based Chemical Methodology for Efficient Synthesis of Cyclic Disulfide Peptides2018
- Author(s)
  Akihiro Taguchi, Kiyotaka Kobayashi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  54th International Conference on Medicinal Chemistry (RICT2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] A New Aspect of Npys-based Solid Phase Disulfide Peptide Synthesis2018
- Author(s)
  Akihiro Taguchi, Kyohei Muguruma, Kiyotaka Kobayashi, Yan Cui, Cedric Rentier, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  35th European Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of On-resin Synthesis of Cyclic Disulfide Peptides Using Methyl 3-Nitro-2-pyridinesulfenate2018
- Author(s)
  Kiyotaka Kobayashi, Akihiro Taguchi, Kyohei Muguruma, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  10th International Peptide Symposium / 55th Japanese Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 固相上ジスルフィド形成反応を利用した環状ペプチドの効率的合成法の開発2018
- Author(s)
  田口　晃弘，小林　清孝，崔岩，高山　健太郎，谷口　敦彦，林　良雄
- Organizer
  第44回反応と合成の進歩シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of 4-fluorophenyl 3-nitro-2-pyridinesulfenate as an appropriate surrogate for conventional sulfenylation agent Npys-Cl2018
- Author(s)
  Yan Cui, Cedric Rentier, Akihiro Taguchi, Kiyotaka Kobayashi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  22nd KPPS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of 4-fluorophenyl 3-nitro-2-pyridinesulfenate as an appropriate surrogate for sulfenylation agent Npys-Cl2018
- Author(s)
  Yan Cui, Cedric Rentier, Akihiro Taguchi, Kiyotaka Kobayashi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  15th Chinese International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Water-soluble Npys-OMe Derivatives for Organic Solvent Free Disulfide-Bond Formation2018
- Author(s)
  Akihiro Taguchi, Saeka Kuraishi, Kiyotaka Kobayashi, Yan Cui, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  10th International Peptide Symposium / 55th Japanese Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 新規3-ニトロ-2-ピリジンスルフェン酸エステル誘導体の創製とその機能性評価2018
- Author(s)
  崔　岩、レンティール　セドリック、田口　晃弘、小林　清孝、高山　健太郎、谷口　敦彦、林　良雄
- Organizer
  日本ケミカルバイオロジー学会第１３回年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 固相Npys試薬を利用したジスルフィド先導型環状ペプチド合成によるヒトエンドセリン－２の合成2018
- Author(s)
  小林　清孝、田口　晃弘、崔　岩、福元　早穂子、倉石　彩恵香、高山　健太郎、谷口　敦彦、林　良雄
- Organizer
  日本ケミカルバイオロジー学会第１３回年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of a novel disulfide-forming agent and its application to on-resin synthesis of cyclic disulfide peptides2018
- Author(s)
  Kiyotaka Kobayashi, Akihiro Taguchi, Akira Kotani, Kyohei Muguruma, Yan Cui, Kentarou Fukumoto, Kentaro Takayama, Atsuhiko Taniguchi, Hideki Hakamata, Yoshio Hayashi
- Organizer
  XXII International Conference on Organic Synthesis-22-ICOS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Solid-phase Synthesis of Cyclic Peptides Using a New Disulfide-forming Agent Npys-OMe2018
- Author(s)
  Kiyotaka Kobayashi, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  22nd KPPS Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Npys-Based Solid Phase Disulfide-Peptide Synthesis And Its Application To Peptide-Drug Conjugates2018
- Author(s)
  Akihiro Taguchi, Kyohei Muguruma, Yoshio Hayashi
- Organizer
  10th International Peptide Symposium / 55th Japanese Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 3-ニトロ-2-ピリジンスルフェニル(Npys)構造を基盤とした新規ジスルフィド架橋試薬の創製研究2017
- Author(s)
  小林　清孝、田口　晃弘、小谷　明、六車　共平、小林　美咲、崔　岩、福元　謙太郎、高山　健太郎、谷口　敦彦、袴田　秀樹、林　良雄
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 環状ジスルフィドペプチドの効率的合成を指向した新規ジスルフィド架橋試薬の創製2017
- Author(s)
  小林　清孝、田口　晃弘、小谷　明、六車　共平、小林　美咲、崔　岩、福元　謙太郎、高山　健太郎、谷口　敦彦、袴田　秀樹、林　良雄
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of a new method on Npys-based disulfide bond formation for the preparation of bioactive cyclic disulfide peptides2017
- Author(s)
  Akihiro Taguchi, Kiyotaka Kobayashi, Akira Kotani, Kyohei Muguruma, Misaki Kobayashi, Kentarou Fukumoto, Kentaro Takayama, Atsuhiko Taniguchi, Hideki Hakamata, Yoshio Hayashi
- Organizer
  12th Annual Peptide Therapeutics Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of a disulfide bond-forming agent toward efficient multi-disulfide peptide synthesis2017
- Author(s)
  Kiyotaka Kobayashi, Akihiro Taguchi, Akira Kotani, Kyohei Muguruma, Misaki Kobayashi, Yan Cui, Kentarou Fukumoto, Kentaro Takayama, Hideki Hakamata, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  3rd Annual Peptides and Proteins Symposium Singapore
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Application of 3-Nitro-2-Pyridinesulfenyl (Npys) Derivatives to Chemical Biology, Peptide Chemistry and Medicinal Chemistry2017
- Author(s)
  Akihiro Taguchi, Kentarou Fukumoto, Kyohei Muguruma, Kiyotaka Kobayashi, Kentaro Takayama, Yoshio Hayashi
- Organizer
  The 12th Australian Peptide Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Synthesis and stability evaluation of new 3-nitro-2-pyridinesulfenate derivatives2017
- Author(s)
  Yan Cui, Cedric Rentier, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
- Organizer
  第54回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of New Npys-based Reagents for the Synthesis of Disulfide-containing Peptides2016
- Author(s)
  Kiyotaka Kobayashi, Akihiro Taguchi, Misaki Kobayashi, Kyohei Muguruma, Kentarou Fukumoto, Kentaro Takayama, Yoshio Hayashi
- Organizer
  20th Korean Peptide Protein Symposium
- Place of Presentation
  韓国
- Year and Date
  2016-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 3-ニトロ-2-ピリジンスルフェニル（Npys）を基盤とした新規ジスルフィド形成試薬の開発2016
- Author(s)
  小林清孝、田口晃弘、小林美咲、六車共平、福元謙太郎、高山健太郎、林　良雄
- Organizer
  創薬懇話会2016 in 蓼科
- Place of Presentation
  長野
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] Development of New Npys-based Disulfide Formation Reagents for the Synthesis of Cyclic Disulfide Peptides2016
- Author(s)
  Akihiro Taguchi, Kiyotaka Kobayashi, Kentarou Fukumoto, Misaki Kobayashi, Kyohei Muguruma, Kentaro Takayama, Yoshio Hayashi
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] 3-ニトロ-2-ピリジンスルフェニル基を基盤とした新規ジスルフィド形成手法の創製とその応用2016
- Author(s)
  田口晃弘、小林清孝、福元謙太郎、小林美咲、六車共平、濵田圭佑、高山健太郎、林　良雄
- Organizer
  第42回反応と合成の進歩シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2016-11-07
- Data Source
  KAKENHI-PROJECT-16K18914
[Presentation] エステル型ネガマイシン誘導体の合成とそのリードスルー活性評価2014
- Author(s)
  会田　俊、濵田圭佑、小竹優也、生澤俊太郎、塩塚政孝、野々村禎昭、田口晃弘、高山健太郎、薬師寺文華、臼井健郎、松田良一、林　良雄
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25893258
[Presentation] Structure Activity Relationship Study of (+)-Negamycin for Potent Readthrough-Promoting Activity at Nonsense Mutations2013
- Author(s)
  Akihiro Taguchi, Keisuke Hamada, Masaya Kotake, Masataka Shiozuka, Kentaro Takayama, Fumika Yakushiji, Yoshiaki Nonomura, Ryoichi Matsuda, Yoshio Hayashi
- Organizer
  4th Asia-Pacific International Peptide Symposium/50th Japanese Peptide Sympodsium
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25893258
[Presentation] 創薬合成研究からのリードスルー活性を有する天然物の発見2013
- Author(s)
  田口晃弘、濵田圭佑、小竹優也、塩塚政孝、高山健太郎、薬師寺文華、野々村禎昭、松田良一、林良雄
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-25893258
[Presentation] Structure activity relationship study of (+)- negamycin derivatives at the C-terminal part as a readthrough drug
- Author(s)
  Keisuke Hamada, Akihiro Taguchi, Masaya Kotake, Suguru Aita, Shuntaro Ikezawa, Masataka Shiozuka, Yoshiaki Nonomura, Kentaro Takayama, Fumika Yakushiji, Takeo Usui, Ryoichi Matsuda, Yoshio Hayashi
- Organizer
  18th Korean Peptide Protein Symposium
- Place of Presentation
  Busan, South Korea
- Year and Date
  2014-07-07 – 2014-07-08
- Data Source
  KAKENHI-PROJECT-25893258
[Presentation] リードスルー作用を有するネガマイシン誘導体のC末端部位における構造活性相関研究
- Author(s)
  田口晃弘、濵田圭佑、小竹優也、塩塚政孝、会田　俊、生澤俊太郎、村上沙織、鈴木奈々、高山健太郎、薬師寺文華、野々村禎昭、臼井健郎、松田良一、林　良雄
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25893258
[Presentation] Structure Activity Relationship Study of (+)-Negamycin for Readthrough Activity at Duchenne Muscular Dystrophy
- Author(s)
  Akihiro Taguchi, Keisuke Hamada, Masaya Kotake, Masataka Shiozuka, Kentaro Takayama, Fumika Yakushiji, Takeo Usui, Ryoichi Matsuda, Yoshio Hayashi
- Organizer
  33rd European Peptide Symposium
- Place of Presentation
  Sofia, Bulgaria
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25893258
[Presentation] ネガマイシン誘導体におけるC末端部修飾とリードスルー活性への効果
- Author(s)
  濵田圭佑、田口晃弘、小竹優也、生澤俊太郎、会田　俊、塩塚政孝、野々村禎昭、高山健太郎、薬師寺文華、臼井健郎、松田良一、林　良雄
- Organizer
  創薬懇話会2014
- Place of Presentation
  岐阜
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25893258

1. 林良雄 (10322562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 63 results
2. TAKAYAMA Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. HITACHI Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 谷口敦彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
5. 臼井健朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 加香孝一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中野祥吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 土田邦博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taguchi Akihiro 田口 晃弘

TAGUCHI Akihiro 田口 晃弘

Research Projects

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Co-Researchers

Npys化学を基盤としたトリプトファン残基選択的修飾法の開発と生体分子への応用Principal Investigator

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Development of disulfide-driven cyclic peptide synthesis based on Npys derivativesPrincipal Investigator

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Synthesis and Medicinal Chemical Development of Mid-Sized Peptide Conjugate Based on the Chemistry of Solid-Phase Disulfide Ligation

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Development of thiol-selective disulfide forming reagent for the application to peptide chemistryPrincipal Investigator

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Study of medicinal chemistry of nonsense mutation disease therapeutics focused on negamycin with readthrough activityPrincipal Investigator

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[Book] ファルマシア2014

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[Journal Article] Development of Myostatin Inhibitory D-Peptides to Enhance the Potency Increasing Skeletal Muscle Mass in Mice2022

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[Journal Article] Structural revision of natural cyclic depsipeptide MA026 established by total synthesis and biosynthetic gene cluster analysis2021

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[Journal Article] Development of a high‐affinity antibody‐binding peptide for site‐specific modification.2021

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[Journal Article] Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation2021

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[Journal Article] Proposal for the Binding Mode of the 23-Mer Inhibitory Peptide to Myostatin2021

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[Journal Article] “On-Resin” disulfide peptide synthesis with methyl 3-nitro-2-pyridinesulfenate2021

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[Journal Article] Use of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate in the construction of disulfide- linked hybrid molecules2020

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[Journal Article] Disulfide-Driven Cyclic Peptide Synthesis of Human Endothelin-2 with a Solid-Supported Npys-Cl2020

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Taguchi Akihiro 田口晃弘

TAGUCHI Akihiro 田口晃弘