Hirano Kazumi 平野和己

Researcher Number	40707709
Other IDs
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2018: 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 2015 – 2016: 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 研究員
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Medical genome science Except Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator 神経幹細胞 / 大脳オルガノイド / 神経疾患 / 脳オルガノイド / DNAメチル化 / エピジェネティクス / 大脳発生 / オルガノイド / エピジェネテジクス / ペリセントロメア … More / ICF症候群 / エピゲノム / 神経発生 / マルチ電極アレイ / 創薬スクリーニング / てんかん / 海馬発生 / 海馬 / 創薬 / メチル化 / 疾患モデル細胞 / ジンクフィンガー / LSD1 / DNMT / エピゲノム編集 / 精神疾患 … More Except Principal Investigator マイクロニードル / 抗体 / CLIC1 / 大脳オルガノイド / 膠芽腫 / 分化 / オルガノイド / アクチン繊維 / アクチンペイント法 Less

膠芽腫治療に向けた深部導入型膠芽腫オルガノイドの構築と抗CLIC1抗体の高機能化
- Principal Investigator
  
  中村史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
アクチンペイント法によるオルガノイドの品質評価システムの開発
- Principal Investigator
  
  長崎晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of pericentromere-specific epigenome editing technology and application to new human cerebral development modelPrincipal Investigator
- Principal Investigator
  
  Hirano Kazumi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of Cerebral Organoids and Multi-Sample Analysis Technology for Drug Discovery of Neurological DiseasesPrincipal Investigator
- Principal Investigator
  
  hirano Kazumi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Establishment of drug screening system for mental disorder by generation of novel epigenome editing proteinsPrincipal Investigator
- Principal Investigator
  
  Hirano Kazumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical genome science
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2022 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] PRC2-dependent regulation of ganglioside expression during dedifferentiation contributes to the proliferation and migration of vascular smooth muscle cells2022
- Author(s)
  Sasaki Norihiko、Hirano Kazumi、Shichi Yuuki、Itakura Yoko、Ishiwata Toshiyuki、Toyoda Masashi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 01-01
- DOI
  10.3389/fcell.2022.1003349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11666, KAKENHI-PROJECT-18KK0443, KAKENHI-PROJECT-21K19754
[Journal Article] Comparison of functional glycans between cancer stem cells and normal stem cells.2019
- Author(s)
  Norihiko Sasaki, Yoko Itakura, Fujiya Gomi, Kazumi Hirano, Masashi Toyoda, and Toshiyuki Ishiwata
- Journal Title
  
  Histol Histopathol
  
  Volume: 34 Pages: 0000-0000
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15056
[Journal Article] New insight into LSD1 function in human cortical neurogenesis.2016
- Author(s)
  Hirano K, Namihira M.
- Journal Title
  
  Neurogenesis
  
  Volume: 3 Issue: 1 Pages: e1249195-e1249195
- DOI
  10.1080/23262133.2016.1249195
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430083, KAKENHI-PROJECT-15K21661
[Journal Article] LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling the Expression of a Novel Target Gene, HEYL.2016
- Author(s)
  Hirano K, Namihira M.
- Journal Title
  
  Stem Cells
  
  Volume: 34 Issue: 7 Pages: 1-11
- DOI
  10.1002/stem.2362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430083, KAKENHI-PROJECT-15K21661
[Presentation] Lysine-Specific Demethylase 1 (LSD1) and its downstream target gene HEYL are important for neurogenesis of human fetal neural stem cells2017
- Author(s)
  Kazumi Hirano, Masakazu Namihira
- Organizer
  KEYSTONE SYMPOSIA (J2)
- Place of Presentation
  Resort at Squaw Creek, California, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21661
[Presentation] ヒストン脱メチル化酵素LSD1はヒト神経幹細胞のニューロン分化を制御する2016
- Author(s)
  平野和己、波平昌一
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K21661
[Presentation] LSD1はヒト神経幹細胞のGABA作動性ニューロンへの分化を制御する2015
- Author(s)
  平野和己、波平昌一
- Organizer
  第9回日本エピジェネティクス研究会年会
- Place of Presentation
  東京/学術総合センター一橋講堂
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15K21661
[Presentation] Histone demethylase LSD1 controls Notch signaling and GABAergic neuronal differentiation in human neural stem cell2015
- Author(s)
  Kazumi Hirano, Masakazu Namihira
- Organizer
  Society for Neuroscience Neuroscience 2015
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21661

1. 長崎晃 (30392640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 中村史 (40357661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山岸彩奈 (00778293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 杉浦慎治 (10399496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 浅野竜太郎 (80323103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ITAKURA Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 波平昌一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirano Kazumi 平野 和己

Research Projects

Research Products

Co-Researchers

膠芽腫治療に向けた深部導入型膠芽腫オルガノイドの構築と抗CLIC1抗体の高機能化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アクチンペイント法によるオルガノイドの品質評価システムの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of pericentromere-specific epigenome editing technology and application to new human cerebral development modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Cerebral Organoids and Multi-Sample Analysis Technology for Drug Discovery of Neurological DiseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of drug screening system for mental disorder by generation of novel epigenome editing proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] PRC2-dependent regulation of ganglioside expression during dedifferentiation contributes to the proliferation and migration of vascular smooth muscle cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of functional glycans between cancer stem cells and normal stem cells.2019

Author(s)

Journal Title

Data Source

[Journal Article] New insight into LSD1 function in human cortical neurogenesis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling the Expression of a Novel Target Gene, HEYL.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Lysine-Specific Demethylase 1 (LSD1) and its downstream target gene HEYL are important for neurogenesis of human fetal neural stem cells2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ヒストン脱メチル化酵素LSD1はヒト神経幹細胞のニューロン分化を制御する2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] LSD1はヒト神経幹細胞のGABA作動性ニューロンへの分化を制御する2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Histone demethylase LSD1 controls Notch signaling and GABAergic neuronal differentiation in human neural stem cell2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Hirano Kazumi 平野和己