Koide Naoshi 小出直史

… Alternative Names

小出直史コイデナオシ

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Researcher Number	40714126
Other IDs
Affiliation (Current)	2025: 大阪大学, 感染症総合教育研究拠点, 特任准教授(常勤) 2025: 名古屋大学, 未来社会創造機構, 特任准教授
Affiliation (based on the past Project Information) *help	2020 – 2021: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 客員研究員 2018 – 2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2016 – 2017: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 研究員 2009 – 2011: Nagoya University, 大学院・医学系研究科, 特別研究員(DC1)
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 56060:Ophthalmology-related / Conservation of biological resources
Keywords	Principal Investigator 再生医療 / ノックダウン / shRNA / siRNA / MYCNトランスジェニックマウス / 神経幹細胞 / Tumor sphere / 自然発症モデル / Pik3r1 / Dock4 … More / Csrnp3 / tumor sphere / マイクロアレイ / MYCN / 神経芽腫 / 移植用細胞製剤 / 細胞品質 / 製剤化 / 移植手術 / 細胞選別 / 品質管理 / 移植剤型 / 網膜色素上皮 / 低温 / 細胞・組織・種子保存 / 眼発生・再生医学 / 網膜組織 / RPE / 蛍光異方性 / 不凍タンパク質 / 細胞保存 / 細胞移植 / 網膜 Less

Development of optimal cell preparation for maximizing post-transplant functionPrincipal Investigator
- Principal Investigator
  
  小出直史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Institute of Physical and Chemical Research
Development of a cooling preservation method that secures the function of retinal tissue for regenerative medicinePrincipal Investigator
- Principal Investigator
  
  Koide Naoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservation of biological resources
- Research Institution
  Institute of Physical and Chemical Research
神経芽腫モデルマウスを用いた新規制御因子の探索と機能解析Principal Investigator
- Principal Investigator
  
  小出直史
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University

All 2020 2019 2018 2017 2016 2012 2011 2010 2009

All Journal Article Presentation Book Patent

[Book] 難治性腹圧性尿失禁症例,脂肪組織由来幹細胞注入療法の経直腸造影超音波イメージング2010
- Author(s)
  山本徳則, 青木重之, 小出直史, 舟橋康人, 佐々直人, 吉野能, 河津政範, 土屋拓真, 青木久佳, 服部良平, 後藤百万
- Publisher
  日本超音波医学会
- Data Source
  KAKENHI-PROJECT-09J00808
[Book] Vector flow mappingを用いた大動脈-腎動脈血管分岐部血流構造の解析の試み2010
- Author(s)
  山本徳則, 青木重之, 小出直史, 舟橋康人, 佐々直人, 吉野能, 河津政範, 土屋拓真, 青木久佳, 服部良平, 後藤百万
- Publisher
  日本超音波医学会
- Data Source
  KAKENHI-PROJECT-09J00808
[Book] 腎腫瘍に対する造影剤ソナゾイドを用いた微小血流解析からの鑑別診断2010
- Author(s)
  山本徳則, 青木重之, 舟橋康人, 佐々直人, 小出直史, 青木久佳, 土屋拓真, 吉野能, 服部良平, 後藤百万.
- Publisher
  日本腎泌尿器科疾患予防医学研究会誌(In press)
- Data Source
  KAKENHI-PROJECT-09J00808
[Journal Article] Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium2020
- Author(s)
  Matsuzaki Mitsuhiro、Mandai Michiko、Yamanari Masahiro、Totani Kota、Nishida Mitsuhiro、Sugita Sunao、Maeda Tadao、Koide Naoshi、Takagi Seiji、Hirami Yasuhiko、Miyamoto Noriko、Sugiyama Satoshi、Takahashi Masayo、Kurimoto Yasuo
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 7656-7656
- DOI
  10.1038/s41598-020-64601-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18864, KAKENHI-PROJECT-18H02959
[Journal Article] Melanin concentration and depolarization metrics measurement by polarization-sensitive optical coherence tomography2020
- Author(s)
  Yamanari Masahiro、Mase Mutsuki、Obata Ryo、Matsuzaki Mitsuhiro、Minami Takahiro、Takagi Seiji、Yamamoto Motoshi、Miyamoto Noriko、Ueda Koji、Koide Naoshi、Maeda Tadao、Totani Kota、Aoki Nobuyori、Hirami Yasuhiko、Sugiyama Satoshi、Mandai Michiko、Aihara Makoto、Takahashi Masayo、Kato Satoshi、Kurimoto Yasuo
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 19513-19513
- DOI
  10.1038/s41598-020-76397-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18864
[Journal Article] HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration2020
- Author(s)
  Sugita Sunaoら他32名
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 7 Pages: 2217-2217
- DOI
  10.3390/jcm9072217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09772, KAKENHI-PROJECT-19K18864, KAKENHI-PROJECT-18H02959, KAKENHI-PROJECT-19H01063
[Journal Article] A simple and static preservation system for shipping retinal pigment epithelium cell sheets2019
- Author(s)
  Hori Kanji、Kuwabara Junichi、Tanaka Yuji、Nishida Mitsuhiro、Koide Naoshi、Takahashi Masayo
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 13 Issue: 3 Pages: 459-468
- DOI
  10.1002/term.2805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21633, KAKENHI-PROJECT-19K18864
[Journal Article] Fabricating retinal pigment epithelial cell sheets derived from human induced pluripotent stem cells in an automated closed culture system for regenerative medicine2019
- Author(s)
  Matsumoto Erino、Koide Naoshi、Hanzawa Hiroko、Kiyama Masaharu、Ohta Mari、Kuwabara Junichi、Takeda Shizu、Takahashi Masayo
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 3 Pages: e0212369-e0212369
- DOI
  10.1371/journal.pone.0212369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21633, KAKENHI-PROJECT-19K18864
[Journal Article] Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation2018
- Author(s)
  Iraha Satoshi、Tu Hung-Ya、Yamasaki Suguru、Kagawa Takahiro、Goto Motohito、Takahashi Riichi、Watanabe Takehito、Sugita Sunao、Yonemura Shigenobu、Sunagawa Genshiro A.、Matsuyama Take、Fujii Momo、Kuwahara Atsushi、Kishino Akiyoshi、Koide Naoshi、Eiraku Mototsugu、Tanihara Hidenobu、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Issue: 3 Pages: 1059-1074
- DOI
  10.1016/j.stemcr.2018.01.032
- NAID
  120007037461
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994, KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-17H04351, KAKENHI-PROJECT-15K10913, KAKENHI-PROJECT-18H02959, KAKENHI-PROJECT-16K21633
[Journal Article] Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1.2017
- Author(s)
  Ode KL, Ukai H, Susaki EA, Narumi R, Matsumoto K, Hara J, Koide N, Abe T, Kanemaki MT, Kiyonari H, Ueda HR.
- Journal Title
  
  Molecular Cell
  
  Volume: 65 Pages: 176-190
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21633
[Journal Article] ESTABLISHMENT AND OPTIMAL CULTURE CONDITIONS OF MICRORNA-INDUCED PLURIPOTENT STEM CELLS GENERATED FROM HEK293 CELLS VIA TRANSFECTION OF MICRORNA-302S EXPRESSION VECTOR2012
- Author(s)
  N Koide, K Yasuda, K Kadomatsu, Y Takei
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 74 Pages: 157-165
- NAID
  120003837128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J00808
[Journal Article] Establishment and characterization of a noradrenergic adrenal chromaffin cell line, tsAM5NE, immortalized with the temperature-sensitive SV40 T-antigen2011
- Author(s)
  Kohno S, Murata T, Koide N, Hikita K, Kaneda N
- Journal Title
  
  Cell Biol Int.
  
  Volume: 35 Pages: 325-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J00808
[Journal Article] The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma2011
- Author(s)
  Huang P, Kishida S, Cao D, Murakami-Tonami Y, Mu P, Nakaguro M, Koide N, Takeuchi I, Onishi A, Kadomatsu K
- Journal Title
  
  Cancer Res.
  
  Volume: 71 Pages: 2938-2948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J00808
[Journal Article] NeuroD1 Downregulates Slit2 Expression and Promotes Cell Motility and Tumor Formation of Neuroblastoma.2011
- Author(s)
  Huang P, Kishida S, Cao D, Murakami-Tonami Y, Mu P, Nakaguro M, Koide N, Takeuchi I, Onishi A, Kadomatsu K.
- Journal Title
  
  Cancer Res.
  
  Volume: (In press)(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J00808
[Journal Article] Establishment and characterization of a noradrenergic adrenal chromaffin cell line, tsAM5NE, immortalized with the temperature-sensitive SV40 T-antigen.2010
- Author(s)
  Kohno S, Murata T, Koide N, Hikita K, Kaneda N.
- Journal Title
  
  Cell Biol Int.
  
  Volume: (In press)(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J00808
[Patent] 脂肪組織由来間葉系幹細胞を含有する、勃起全又は尿意障害用の細胞製剤2009
- Inventor(s)
  山本徳則, 小出直史, 武井佳史, 松川宣久, 舟橋康人, 後藤百万.
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2009-232068
- Filing Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-09J00808
[Patent] 脂肪組織由来間葉系幹細胞を含有する、前立腺癌治療用細胞製剤2009
- Inventor(s)
  山本徳則, 小出直史, 後藤百万, 武井佳史
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2009-277439
- Filing Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-09J00808
[Presentation] The Dawn of Machine Culture2016
- Author(s)
  小出直史
- Organizer
  The 2nd RIKEN QBiC-CDB Joint Workshop
- Place of Presentation
  理研CDB（神戸市）
- Data Source
  KAKENHI-PROJECT-16K21633
[Presentation] Comprehensive analysis of array-based platforms for mirPS ceils reprogrammed from HEK293 cells by transduction of miR-302 family2011
- Author(s)
  N Koide, Y Takei
- Organizer
  日本生化学会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-09J00808
[Presentation] Isolation of tumor-initiating cells from tumors of MYCN-transgenic mice2010
- Author(s)
  小出直史
- Organizer
  日本生化学会中部支部例会
- Place of Presentation
  名古屋大学大学院医学系研究科(愛知県)
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-09J00808
[Presentation] Isolation of tumor-iitiating cells from tumors MYCN-transgenic mice.2009
- Author(s)
  小出直史
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-09J00808

1. SUNAGAWA Genshiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. TSUDA Sakae

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Tu HungYa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koide Naoshi 小出 直史

小出 直史 コイデ ナオシ

Research Projects

Research Products

Co-Researchers

Development of optimal cell preparation for maximizing post-transplant functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a cooling preservation method that secures the function of retinal tissue for regenerative medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経芽腫モデルマウスを用いた新規制御因子の探索と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 難治性腹圧性尿失禁症例,脂肪組織由来幹細胞注入療法の経直腸造影超音波イメージング2010

Author(s)

Publisher

Data Source

[Book] Vector flow mappingを用いた大動脈-腎動脈血管分岐部血流構造の解析の試み2010

Author(s)

Publisher

Data Source

[Book] 腎腫瘍に対する造影剤ソナゾイドを用いた微小血流解析からの鑑別診断2010

Author(s)

Publisher

Data Source

[Journal Article] Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Melanin concentration and depolarization metrics measurement by polarization-sensitive optical coherence tomography2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A simple and static preservation system for shipping retinal pigment epithelium cell sheets2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fabricating retinal pigment epithelial cell sheets derived from human induced pluripotent stem cells in an automated closed culture system for regenerative medicine2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1.2017

Author(s)

Journal Title

Data Source

[Journal Article] ESTABLISHMENT AND OPTIMAL CULTURE CONDITIONS OF MICRORNA-INDUCED PLURIPOTENT STEM CELLS GENERATED FROM HEK293 CELLS VIA TRANSFECTION OF MICRORNA-302S EXPRESSION VECTOR2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Establishment and characterization of a noradrenergic adrenal chromaffin cell line, tsAM5NE, immortalized with the temperature-sensitive SV40 T-antigen2011

Author(s)

Journal Title

Data Source

[Journal Article] The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma2011

Koide Naoshi 小出直史

小出直史コイデナオシ