HAYASHI Yushi 林裕史

Researcher Number	40715166
Affiliation (Current)	2019: 独立行政法人国立病院機構(東京医療センター臨床研究センター), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2015 – 2017: 独立行政法人国立病院機構(東京医療センター臨床研究センター), その他部局等, 研究員 2016: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 政策医療企画研究部, 研究員 2014: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 政策医療企画研究部, 医師 2013: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 政策医療企画研究部, 研究員
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator 蝸牛 / 有毛細胞 / 感音難聴 / ウイルス感染 / 自然免疫 / 支持細胞 / I型IFN / RIG-I family / Ｉ型IFN / マクロファージ … More Except Principal Investigator メニエール病 / 片頭痛 / 馴化 / 聴性誘発電位 / 前庭誘発筋電位 / 前庭眼反射 / めまい / 鑑別診断 / 内リンパ水腫 / 耳石器 / 半規管 Less

聴平衡覚刺激に対する馴化を指標とした前庭性片頭痛の客観的診断法の確立Ongoing
- Principal Investigator
  
  室伏利久
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Teikyo University
Research on the functional analysis of tissue-specific macrophages in the cochlea and the etiology of sensorineural hearing lossPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yushi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Prevention and treatment for sensorineural hearing loss by controlling the system of innate immunityPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yushi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Otorhinolaryngology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)

All 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Microtia and Atretia. Temporal bone computed tomography of patients with poor postoperative hearing improvement after surgery for atresia of the external auditory canal.2014
- Author(s)
  Hayashi Y, Kaga K.
- Total Pages
  4
- Publisher
  Karger
- Data Source
  KAKENHI-PROJECT-25893299
[Journal Article] Activation of IGF1 Signaling in the Cochlea Induces the Transcription of Its Mediators During the Protection of Cochlear Hair Cells Against Aminoglycoside2017
- Author(s)
  Hayashi Y, Yamamoto N, Nakagawa T, Omori K, Ito J.
- Journal Title
  
  Otol Neurotol
  
  Volume: 38 Pages: 278282-278282
- DOI
  10.1097/mao.0000000000001276
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462638, KAKENHI-PROJECT-26462557, KAKENHI-PROJECT-15K20240, KAKENHI-PROJECT-15K10749
[Journal Article] Is otolithic vrtigoaccompanied by hearing loss caused by sacculocochlear endolymphatic hydrops?2016
- Author(s)
  Murofushi T, Komiyama S, Hayashi Y, Yoshimura E.
- Journal Title
  
  Acta Otolaryngologica
  
  Volume: 136(1) Pages: 38-42
- DOI
  10.3109/00016489.2015.1081277
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20240, KAKENHI-PROJECT-15K10764
[Journal Article] VEMP所見異常と治療による回復を認めた中枢神経系脱髄疾患の一症例2016
- Author(s)
  室伏利久、林裕史、松崎真樹、室伏利久
- Journal Title
  
  Equilibrium Research
  
  Volume: 75 Pages: 16-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10764
[Journal Article] VEMP所見異常と治療による回復を認めた中枢神経系脱髄疾患の一症例．2016
- Author(s)
  小宮山櫻子林裕史　松崎真樹　室伏利久
- Journal Title
  
  Ｅｑｕｉｌｉｂｒｉｕｍ　Ｒｅｓｅａｒｃｈ
  
  Volume: 75 Pages: 16-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10764
[Journal Article] Frequency preference in cervical vestibular evoked myogenic potential of idiopathic otolithic vertigo patients. Does it reflect otolithic endolymphatic hydrops?2015
- Author(s)
  Murofushi T, Komiyama S, Hayashi Y, Yoshimura E
- Journal Title
  
  Acta Otolaryngol.
  
  Volume: 135 Pages: 995-999
- DOI
  10.3109/00016489.2015.1022834
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10764, KAKENHI-PROJECT-15K20240
[Journal Article] Insulin-like growth factor 1 induces the transcription of Gap43 and Ntn1 during hair cell protection in the neonatal murine cochlea.2014
- Author(s)
  Hayashi Y, Yamamoto N, Nakagawa T, Ito J.
- Journal Title
  
  Neurosci Lett
  
  Volume: 560 Pages: 7-11
- DOI
  10.1016/j.neulet.2013.11.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229009, KAKENHI-PROJECT-24592545, KAKENHI-PROJECT-25893299
[Journal Article] Insulin-like growth factor 1 inhibits hair cell apoptosis and promotes the cell cycle of supporting cells by activating different downstream cascades after pharmacological hair cell injury in neonatal mice.2013
- Author(s)
  Hayashi Y, Yamamoto N, Nakagawa T, Ito J.
- Journal Title
  
  Mol Cell Neurosci.
  
  Volume: 56 Pages: 29-38
- DOI
  10.1016/j.mcn.2013.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229009, KAKENHI-PROJECT-24592545, KAKENHI-PROJECT-25893299
[Journal Article] Virus-induced expression of retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 in the cochlear sensory epithelium.2013
- Author(s)
  Hayashi Y, Onomoto K, Narita R, Yoneyama M, Kato H, Nakagawa T, Ito J, Taura A, Fujita T.
- Journal Title
  
  Microbes. Infect.
  
  Volume: 15 Pages: 592-598
- DOI
  10.1016/j.micinf.2013.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229009, KAKENHI-PUBLICLY-25115503, KAKENHI-PROJECT-25893299
[Presentation] 難聴を伴う耳石器性めまい症例．2015
- Author(s)
  室伏利久、小宮山櫻子、林　裕史、松﨑真樹、津田幸子、吉村恵理子
- Organizer
  第116回日本耳鼻咽喉科学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-15K10764
[Presentation] IFN/IFNAR1 SIGNALING IS CRUCIAL IN THE CONTROL OF VIRAL INFECTION IN THE COCHLEAR SENSORY EPITHELIUM2015
- Author(s)
  Yushi Hayashi, Koji Onomoto, Mitsutoshi Yoneyama, Takashi Fujita, Nobuyuki Tanaka
- Organizer
  Inner Ear Biology Workshop 2015
- Place of Presentation
  Rome, Italy
- Year and Date
  2015-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20240
[Presentation] ウイルス感染時に支持細胞において発現するtype I interferonが蝸牛感覚上皮に与える影響2015
- Author(s)
  林裕史
- Organizer
  第25回日本耳科学会総会
- Place of Presentation
  長崎
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-15K20240
[Presentation] メニエール病およびその類縁疾患における内リンパ水腫推定検査としてのグリセロールcVEMPの判定法の検討2015
- Author(s)
  室伏利久、林　裕史
- Organizer
  第25回日本耳科学会
- Place of Presentation
  長崎
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10764
[Presentation] Type I IFN is produced in supporting cells against virus infection of the cochlear sensory epithelium via RIG-I like receptor signaling pathway.2014
- Author(s)
  Hayashi Y, Onomoto K, Narita R, Yoneyama M, Kato H, Taura A, Nakagawa T, Ito J, Fujita T, Kaga K.
- Organizer
  ARO 37th MidWinter Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-25893299
[Presentation] 全身III度の熱傷に対する加療で薬剤性に両耳聾となり、人工内耳埋め込み手術を実施するに至った成人の1例2013
- Author(s)
  林　裕史、竹腰英樹、加我君孝
- Organizer
  第23回日本耳科学会総会
- Place of Presentation
  宮崎市
- Data Source
  KAKENHI-PROJECT-25893299
[Presentation] The Pathogenesis of Sensorineural Hearing Loss During Virus Infection of the Cochlear Sensory Epithelium
- Author(s)
  Yushi Hayashi, Koji Onomoto, Mitsutoshi Yoneyama, Kimitaka Kaga, Takashi Fujita, Nobuyuki Tanaka
- Organizer
  38th Association for Research in Otolaryngology MidWinter Meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2015-02-21 – 2015-02-25
- Data Source
  KAKENHI-PROJECT-25893299
[Presentation] Type I IFN is produced in supporting cells against virus infection of the cochlear sensory epithelium via RIG-I like receptor signaling pathway
- Author(s)
  Yushi Hayashi, Koji Onomoto, Ryo Narita, Mitsutoshi Yoneyama, Hiroki Kato, Akiko Taura, Takayuki Nakagawa, Juichi Ito, Kimitaka Kaga, Takashi Fujita
- Organizer
  Inner Ear Biology 2014 in Kyoto
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-11-01 – 2014-11-04
- Data Source
  KAKENHI-PROJECT-25893299
[Presentation] Type I IFN is produced in supporting cells against virus infection of the cochlear sensory epithelium via RIG-I like receptor signaling pathway
- Author(s)
  Yushi Hayashi, Koji Onomoto, Ryo Narita, Mitsutoshi Yoneyama, Hiroki Kato, Akiko Taura, Takayuki Nakagawa, Juichi Ito, Kimitaka Kaga, Takashi Fujita
- Organizer
  51st Inner Ear Biology Workshop
- Place of Presentation
  Sheffield, UK
- Year and Date
  2014-08-30 – 2014-09-02
- Data Source
  KAKENHI-PROJECT-25893299

1. TANAKA Nobuyuki (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. FUJITA Takashi (10156870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. YONEYAMA Mitsutoshi (40260335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 室伏利久 (30242176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 小宮山櫻子 (20645923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 坪田雅仁 (90436791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMAMOTO Norio

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. TAURA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 伊藤壽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 中川隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

HAYASHI Yushi 林 裕史

Research Projects

Research Products

Co-Researchers

聴平衡覚刺激に対する馴化を指標とした前庭性片頭痛の客観的診断法の確立Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the functional analysis of tissue-specific macrophages in the cochlea and the etiology of sensorineural hearing lossPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prevention and treatment for sensorineural hearing loss by controlling the system of innate immunityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Microtia and Atretia. Temporal bone computed tomography of patients with poor postoperative hearing improvement after surgery for atresia of the external auditory canal.2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Activation of IGF1 Signaling in the Cochlea Induces the Transcription of Its Mediators During the Protection of Cochlear Hair Cells Against Aminoglycoside2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Is otolithic vrtigoaccompanied by hearing loss caused by sacculocochlear endolymphatic hydrops?2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] VEMP所見異常と治療による回復を認めた中枢神経系脱髄疾患の一症例2016

Author(s)

Journal Title

Data Source

[Journal Article] VEMP所見異常と治療による回復を認めた中枢神経系脱髄疾患の一症例．2016

Author(s)

Journal Title

Data Source

[Journal Article] Frequency preference in cervical vestibular evoked myogenic potential of idiopathic otolithic vertigo patients. Does it reflect otolithic endolymphatic hydrops?2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insulin-like growth factor 1 induces the transcription of Gap43 and Ntn1 during hair cell protection in the neonatal murine cochlea.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insulin-like growth factor 1 inhibits hair cell apoptosis and promotes the cell cycle of supporting cells by activating different downstream cascades after pharmacological hair cell injury in neonatal mice.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Virus-induced expression of retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 in the cochlear sensory epithelium.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 難聴を伴う耳石器性めまい症例．2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IFN/IFNAR1 SIGNALING IS CRUCIAL IN THE CONTROL OF VIRAL INFECTION IN THE COCHLEAR SENSORY EPITHELIUM2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ウイルス感染時に支持細胞において発現するtype I interferonが蝸牛感覚上皮に与える影響2015

Author(s)

Organizer

HAYASHI Yushi 林裕史