Setsu Nokitaka 薛宇孝

Researcher Number	40727020
Affiliation (Current)	2025: 独立行政法人国立病院機構(九州がんセンター臨床研究センター), その他部局等, 整形外科医長
Affiliation (based on the past Project Information) *help	2021 – 2022: 独立行政法人国立病院機構(九州がんセンター臨床研究センター), その他部局等, 整形外科医長 2019 – 2020: 九州大学, 医学研究院, 助教 2017 – 2018: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Orthopaedic surgery
Keywords	Principal Investigator 肉腫 / 骨軟部腫瘍 / エリブリン / 未分化多型肉腫 / TLR4 / 骨肉腫 / 免疫 / 化学療法 / 癌 / HIF-1α … More / 微小管 / Tubulin / 平滑筋肉腫 / 悪性末梢神経鞘腫瘍 / 薬剤耐性 / Hypoxia-inducible factor / 低酸素 Less

Investigation of Antitumor Effects through Natural Immune Activation in Malignant Bone and Soft Tissue TumorsPrincipal Investigator
- Principal Investigator
  
  Setsu Nokitaka
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
  Kyushu University
Alleviation of intratumor hypoxia by eribulin mesylate in bone and soft tissue sarcomas.Principal Investigator
- Principal Investigator
  
  Setsu Nokitaka
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University

All 2022 2021 2020 2018 2017

All Journal Article Presentation

[Journal Article] Clinical significance of signal regulatory protein alpha and T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibition motif domain expression in undifferentiated pleomorphic sarcoma2022
- Author(s)
  Ishihara Shin、Iwasaki Takeshi、Kohashi Kenichi、Kawaguchi Kengo、Toda Yu、Fujiwara Toshifumi、Setsu Nokitaka、Endo Makoto、Matsumoto Yoshihiro、Nakashima Yasuharu、Oda Yoshinao
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 1 Issue: 6 Pages: 1-1
- DOI
  10.1007/s00432-022-04078-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09325, KAKENHI-PROJECT-22K09359, KAKENHI-PROJECT-18K16626, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-19K16802, KAKENHI-PROJECT-21K20805, KAKENHI-PROJECT-23K08700, KAKENHI-PROJECT-23K27385
[Journal Article] Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?2021
- Author(s)
  Shimada Eijiro、Endo Makoto、Matsumoto Yoshihiro、Tsuchihashi Kenji、Ito Mamoru、Kusaba Hitoshi、Nabeshima Akira、Nawata Tomoya、Maekawa Akira、Matsunobu Tomoya、Setsu Nokitaka、Fujiwara Toshifumi、Iida Keiichiro、Nakagawa Makoto、Kohashi Kenichi、et al.
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 21 Pages: 4972-4972
- DOI
  10.3390/jcm10214972
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06887, KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-21K09325, KAKENHI-PROJECT-18K16626, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-19K16717, KAKENHI-PROJECT-19K16802
[Journal Article] The association between the expression of PD-L1 and CMTM6 in undifferentiated pleomorphic sarcoma2021
- Author(s)
  Ishihara Shin、Oda Yoshinao、et al.
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 147 Issue: 7 Pages: 2003-2011
- DOI
  10.1007/s00432-021-03616-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-21K06887, KAKENHI-PROJECT-18K16626, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-19K16802
[Journal Article] Activation of TLR4 Signaling Inhibits Progression of Osteosarcoma by Stimulating CD8-positive Cytotoxic Lymphocytes.2020
- Author(s)
  Yahiro K, Matsumoto Y, Yamada H, Endo M, Setsu N, Fujiwara T, Nakagawa M, Kimura M, Shimada E, Okada S, Oda Y, Nakashima Y.
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: - Issue: 5 Pages: 745-758
- DOI
  10.1007/s00262-020-02508-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-19H03771, KAKENHI-PROJECT-18K16626, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-19K16802, KAKENHI-PROJECT-18K09067
[Journal Article] Correction: Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor2018
- Author(s)
  Fukushima Suguru、Endo Makoto、Matsumoto Yoshihiro、Fukushi Jun-ichi、Matsunobu Tomoya、Kawaguchi Ken-ichi、Setsu Nokitaka、IIda Keiichiro、Yokoyama Nobuhiko、Nakagawa Makoto、Yahiro Kenichiro、Oda Yoshinao、Iwamoto Yukihide、Nakashima Yasuharu
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 3 Pages: 0194508-0194508
- DOI
  10.1371/journal.pone.0194508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17K16696
[Journal Article] Class III β-Tubulin Overexpression Induces Chemoresistance to Eribulin in a Leiomyosarcoma Cell Line.2018
- Author(s)
  Yahiro K, Matsumoto Y, Fukushi JI, Kawaguchi KI, Endo M, Setsu N, IIda K, Fukushima S, Nakagawa M, Kimura A, Oda Y, Nakashima Y
- Journal Title
  
  Anal Cell Pathol
  
  Volume: なし Pages: 8987568-8987568
- DOI
  10.1155/2018/8987568
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09067, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-17K16696, KAKENHI-PROJECT-26713046
[Journal Article] Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor2017
- Author(s)
  Fukushima Suguru、Endo Makoto、Matsumoto Yoshihiro、Fukushi Jun-ichi、Matsunobu Tomoya、Kawaguchi Ken-ichi、Setsu Nokitaka、IIda Keiichiro、Yokoyama Nobuhiko、Nakagawa Makoto、Yahiro Kenichiro、Oda Yoshinao、Iwamoto Yukihide、Nakashima Yasuharu
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: 0178064-0178064
- DOI
  10.1371/journal.pone.0178064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16696, KAKENHI-PROJECT-26713046, KAKENHI-PROJECT-15K10449
[Presentation] 骨巨細胞腫における免疫微小環境の検討　デノスマブ前後で主にPD-L1とSIRPαの発現に着目して2022
- Author(s)
  戸田雄, 孝橋賢一, 山元英崇, 石原新, 伊東良広, 薄陽祐, 川口健悟, 山田裕一, 藤原稔史, 薛宇孝, 遠藤誠, 松本嘉寛, 中島康晴, 馬渡正明, 小田義直
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K16802
[Presentation] 骨・軟部肉腫における治療前好中球/リンパ球比(NLR)の予後予測因子としての有用性と治療後変化に関する検討2022
- Author(s)
  横山信彦, 薛宇孝, 吉本昌人
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K16802
[Presentation] 進行軟部肉腫に対する新規治療薬選択における末梢血免疫関連マーカーの有用性2021
- Author(s)
  島田英二郎, 松本嘉寛, 花田麻須大, 遠藤誠, 薛宇孝, 藤原稔史, 飯田圭一郎, 松延知哉, 前川啓, 鍋島央, 中川亮, 木村敦, 廣瀬毅, 金堀将也, 中島康晴
- Organizer
  第54回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K16802
[Presentation] 骨肉腫患者において肺転移巣のCD8+T細胞浸潤と予後は相関する2020
- Author(s)
  八尋健一郎, 松本嘉寛, 山田久方, 遠藤誠, 薛宇孝, 木村敦, 島田英二郎, 廣瀬毅, 小田義直, 中島康晴
- Organizer
  第53回日本整形外科学会　骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K16802
[Presentation] 平滑筋肉腫患者におけるclass 3βチューブリンの発現は予後と相関する2018
- Author(s)
  八尋健一郎, 松本嘉寛, 遠藤誠, 薛宇孝, 木村敦, 小田義直, 中島康晴
- Organizer
  第51回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-17K16696
[Presentation] 進行又は再発悪性軟部腫瘍に対する治療2017
- Author(s)
  薛　宇孝
- Organizer
  第８１回がん化学療法研究会
- Data Source
  KAKENHI-PROJECT-17K16696

1. NAKAGAWA Hidewaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. NAKA Norifumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. KOHASHI Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小田義直

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 西田佳弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 松本嘉寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 山田裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Setsu Nokitaka 薛 宇孝

Research Projects

Research Products

Co-Researchers

Investigation of Antitumor Effects through Natural Immune Activation in Malignant Bone and Soft Tissue TumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Alleviation of intratumor hypoxia by eribulin mesylate in bone and soft tissue sarcomas.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Clinical significance of signal regulatory protein alpha and T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibition motif domain expression in undifferentiated pleomorphic sarcoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The association between the expression of PD-L1 and CMTM6 in undifferentiated pleomorphic sarcoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of TLR4 Signaling Inhibits Progression of Osteosarcoma by Stimulating CD8-positive Cytotoxic Lymphocytes.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correction: Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Class III β-Tubulin Overexpression Induces Chemoresistance to Eribulin in a Leiomyosarcoma Cell Line.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 骨巨細胞腫における免疫微小環境の検討 デノスマブ前後で主にPD-L1とSIRPαの発現に着目して2022

Author(s)

Organizer

Data Source

[Presentation] 骨・軟部肉腫における治療前好中球/リンパ球比(NLR)の予後予測因子としての有用性と治療後変化に関する検討2022

Author(s)

Organizer

Data Source

[Presentation] 進行軟部肉腫に対する新規治療薬選択における末梢血免疫関連マーカーの有用性2021

Author(s)

Organizer

Data Source

[Presentation] 骨肉腫患者において肺転移巣のCD8+T細胞浸潤と予後は相関する2020

Author(s)

Organizer

Data Source

[Presentation] 平滑筋肉腫患者におけるclass 3βチューブリンの発現は予後と相関する2018

Author(s)

Organizer

Data Source

[Presentation] 進行又は再発悪性軟部腫瘍に対する治療2017

Author(s)

Organizer

Data Source

Setsu Nokitaka 薛宇孝

[Presentation] 骨巨細胞腫における免疫微小環境の検討　デノスマブ前後で主にPD-L1とSIRPαの発現に着目して2022