TARUI Megumi 垂井愛

Researcher Number	40727749
Affiliation (based on the past Project Information) *help	2020 – 2021: 東京大学, 医学部附属病院, 客員研究員 2017 – 2019: 東京大学, 保健・健康推進本部, 助教 2016: 国立国際医療研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator General medical chemistry
Keywords	Principal Investigator 炎症性呼吸器疾患 / ブレオマイシン肺 / mTOR / EMT / 細胞接着 / モデルマウス / 肺線維症 / 間質性肺炎 / ｍTOR / 炎症性メディエーター / 気管支喘息 … More Except Principal Investigator … More 脂質メディエーター / リゾリン脂質アシル転移酵素 / 生体膜 / リン脂質 / 生化学 Less

A role of mTOR in inflammatory lung diseasesPrincipal Investigator
- Principal Investigator
  
  Tarui Megumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
The role of LPCAT2 in ashmaPrincipal Investigator
- Principal Investigator
  
  TARUI MEGUMI
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Analysis of biological function regulated by membrane phospholipid diversity
- Principal Investigator
  
  SHINDOU Hideo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  National Center for Global Health and Medicine

All 2020 2014 Other

All Journal Article Presentation

[Journal Article] Active mTOR in Lung Epithelium Promotes Epithelial-Mesenchymal Transition and Enhances Lung Fibrosis2020
- Author(s)
  Saito M, Mitani A, Ishimori T, Miyashita N, Isago H, Mikami Y, Noguchi S, Tarui M, Nagase T.
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: - Issue: 6 Pages: 699-708
- DOI
  10.1165/rcmb.2019-0255oc
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17629, KAKENHI-PROJECT-17K15009, KAKENHI-PROJECT-16H02653
[Journal Article] elective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 22014
- Author(s)
  Tarui,　M., Shindou, H., Kumagai, K., Morimoto, R., Harayama, T., Hashidate, T., Kojima, H., Okabe, T., Nagano, T., Nagase, T., and Shimizu, T.
- Journal Title
  
  J. Lipid Res.
  
  Volume: 55 Issue: 7 Pages: 1386-1396
- DOI
  10.1194/jlr.m049205
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460380, KAKENHI-PROJECT-24229003
[Journal Article] Rapid Production of Platelet-activating Factor Is Induced by Protein Kinase Cα-mediated Phosphorylation of Lysophosphatidylcholine Acyltransferase 2.2014
- Author(s)
  Morimoto, R., Shindou, H., Tarui, M., and Shimizu, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: in press Issue: 22 Pages: 15566-15576
- DOI
  10.1074/jbc.m114.558874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229003, KAKENHI-PROJECT-26460380
[Presentation] High-throughput screeningによるPAF生合成酵素（LPCAT2）阻害剤の同定2014
- Author(s)
  垂井愛、進藤英雄、森本亮、原山武士、橋立智美、熊谷和夫、長野哲雄、長瀬隆英、清水孝雄
- Organizer
  第56回　日本脂質生化学会
- Place of Presentation
  近畿大学　東大阪キャンパス
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-26460380
[Presentation] 生体膜リン脂質多様性形成メカニズム2014
- Author(s)
  進藤　英雄, 森本　亮, 垂井　愛, 衛藤　樹, 原山　武士, 清水　孝雄
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-26460380
[Presentation] PKCαを介した血小板活性化因子合成酵素LPCAT2のリン酸化2014
- Author(s)
  森本亮、進藤英雄、垂井愛、清水孝雄
- Organizer
  第56回　日本脂質生化学会
- Place of Presentation
  近畿大学　東大阪キャンパス
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-26460380
[Presentation] Phosphorylated lysophosphatidylcholine acyltransferase 2 (LPCAT2) mediates rapid platelet-activating factor (PAF) production following PAF- or ATP-stimulation in macrophages
- Author(s)
  Ryo Morimoto, Hideo Shindou, Megumi Tarui, Takao Shimizu
- Organizer
  55th International Conference on the Bioscience of Lipids: Lipids as Mediators of Health and Disease
- Place of Presentation
  University of Aberdeen Aberdeen AB24 3FX Scotland
- Year and Date
  2014-06-23 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-26460380
[Presentation] Rapid phosphorylation and activation of lysophosphatidylcholine acyltransferase 2 via protein kinase c
- Author(s)
  Hideo Shindou, Ryo Morimoto, Megumi Tarui, Takao Shimizu
- Organizer
  FASEB
- Place of Presentation
  Sheraton At The Falls 300 3rd Street Niagara Falls, NY14303
- Year and Date
  2014-06-01 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-26460380

1. SHINDOU Hideo (10401027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. HISHIKAWA Daisuke (10569966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YOSHIDA Tomomi (30610216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HARAYAMA Takeshi (50610218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. HISHIKAWA Yoshiko (60436574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YANAGIDA Keisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. VALENTINE William

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAHASHI Yoshikazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAGATA Katsuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Eto Miki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MORIMOTO Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. AMEMIYA Ami

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TODORIKI Naruha

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ITO Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 清水孝雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TARUI Megumi 垂井 愛

Research Projects

Research Products

Co-Researchers

A role of mTOR in inflammatory lung diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of LPCAT2 in ashmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of biological function regulated by membrane phospholipid diversity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Active mTOR in Lung Epithelium Promotes Epithelial-Mesenchymal Transition and Enhances Lung Fibrosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] elective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 22014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid Production of Platelet-activating Factor Is Induced by Protein Kinase Cα-mediated Phosphorylation of Lysophosphatidylcholine Acyltransferase 2.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] High-throughput screeningによるPAF生合成酵素（LPCAT2）阻害剤の同定2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 生体膜リン脂質多様性形成メカニズム2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PKCαを介した血小板活性化因子合成酵素LPCAT2のリン酸化2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Phosphorylated lysophosphatidylcholine acyltransferase 2 (LPCAT2) mediates rapid platelet-activating factor (PAF) production following PAF- or ATP-stimulation in macrophages

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Rapid phosphorylation and activation of lysophosphatidylcholine acyltransferase 2 via protein kinase c

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

TARUI Megumi 垂井愛