Nishimura Yuya 西村勇哉

Researcher Number	40728218
Other IDs	https://orcid.org/0009-0004-6347-5211
Affiliation (based on the past Project Information) *help	2020 – 2024: 神戸大学, 科学技術イノベーション研究科, 客員准教授 2016 – 2019: 神戸大学, 科学技術イノベーション研究科, 特命助教 2017: 神戸大学, 科学技術イノベーション研究科, 部局研究員 2015: 神戸大学, 学内共同利用施設等, 助教
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Basic Section 90150:Medical assistive technology-related / Medium-sized Section 90:Biomedical engineering and related fields / Medium-sized Section 52:General internal medicine and related fields / Medical systems / Radiation science
Keywords	Principal Investigator ナノ粒子 / X線 / 人工癌幹細胞 / 放射線増感 / すい臓がん / 人工がん幹細胞 / 幹細胞 / 無機ナノ粒子 / in vivo / Affibody … More / 放射線治療 / 放射線増感剤 / 抗癌剤ドキソルビシン / バイオナノカプセル / ドラッグデリバリーシステム … More Except Principal Investigator ナノ粒子 / 過酸化水素 / 放射線照射 / 過酸化チタン / 物理療法 / がん細胞 / マクロファージ / 骨格筋エクソソーム / 酸化チタニウム / 頭頚部がん / ルチン修飾 / 植物成分 / 酸化チタン / ポリフェノール修飾 / 二酸化チタンナノ粒子 / 表面修飾技術 / 無機ナノ粒子 / 金属ナノ粒子 / 表面修飾 / 過酸化チタンナノ粒子 / がん幹細胞 / 放射線応答 / 膵臓がん / cell-targeting / 放射線増感 / DDS / 放射線治療 / 二酸化チタン / バイオナノカプセル / ドラッグデリバリーシステム / ナノテクノロジー / 低侵襲治療システム / 活性酸素種 / 放射線増感剤 / 動注療法 / 動注 Less

Development of treatment system for periodontal disease and oral cancer using bio-compatible titanium dioxide
- Principal Investigator
  
  OGINO CHIAKI
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kobe University
生体免疫を是正・補完する骨格筋複合物理刺激装置の開発
- Principal Investigator
  
  前重伯壮
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90150:Medical assistive technology-related
- Research Institution
  Kobe University
Novel radiosensitizer with inorganic nanoparticles and antibodies assembly
- Principal Investigator
  
  Sasaki Ryohei
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kobe University
Induction of cancer stem cells in pancreatic cancer cells and their treatment with radiosensitized nanoparticlesPrincipal Investigator
- Principal Investigator
  
  Nishimura Yuya
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kobe University
Transarterial infusion of metallic nanoparticles for radiation therapy enhancement
- Principal Investigator
  
  Okada Takuya
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kobe University
Investigation of titanium peroxide nanoparticles for cancer therapy application
- Principal Investigator
  
  Ogino Chiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Kobe University
in vivo applications of next-generation DDS carrier for achieving less-invasive radiation therapyPrincipal Investigator
- Principal Investigator
  
  Nishimura Yuya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kobe University

All 2023 2022 2021 2020 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] A cancer treatment strategy that combines the use of inorganic/biocomplex nanoparticles with conventional radiation therapy2018
- Author(s)
  Morita, K., Nishimura, Y., Suzuki, T., Ogino, C., Kondo, A.
- Total Pages
  527
- Publisher
  Nanoparticle Technology Handbook
- ISBN
  9780444641113
- Data Source
  KAKENHI-PROJECT-16H03194
[Book] 粉砕2017
- Author(s)
  西村勇哉，森田健太，鈴木貴弘，荻野千秋，近藤昭彦
- Total Pages
  5
- Publisher
  無機とバイオの融合ナノ粒子によるがん治療戦略
- Data Source
  KAKENHI-PROJECT-16H03194
[Journal Article] Skeletal myotube-derived extracellular vesicles enhance itaconate production and attenuate inflammatory responses of macrophages2023
- Author(s)
  Yamaguchi A, Maeshige N, Yan J, Ma X, Uemura M, Matsuda M, Nishimura Y, Hasunuma T, Kondo H, Fujino H, Yuan ZM.
- Journal Title
  
  Front Immunol
  
  Volume: 14 Pages: 1099799-1099799
- DOI
  10.3389/fimmu.2023.1099799
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19752, KAKENHI-PROJECT-20KK0227, KAKENHI-PROJECT-18H03130, KAKENHI-PROJECT-23K24711, KAKENHI-PROJECT-23K21864
[Journal Article] <i>In vivo</i> stealthified molecularly imprinted polymer nanogels incorporated with gold nanoparticles for radiation therapy2022
- Author(s)
  Kitayama Yukiya、Yamada Takuya、Kiguchi Kentaro、Yoshida Aoi、Hayashi Shuhei、Akasaka Hiroaki、Igarashi Kazunori、Nishimura Yuya、Matsumoto Yu、Sasaki Ryohei、Takano Eri、Sunayama Hirobumi、Takeuchi Toshifumi
- Journal Title
  
  Journal of Materials Chemistry B
  
  Volume: 10 Issue: 35 Pages: 6784-6791
- DOI
  10.1039/d2tb00481j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06430, KAKENHI-PROJECT-20K08108, KAKENHI-PROJECT-21K07594, KAKENHI-PROJECT-21K07642, KAKENHI-PROJECT-22K07771, KAKENHI-PROJECT-20K21576, KAKENHI-PROJECT-22K19922, KAKENHI-PROJECT-20KK0192
[Journal Article] Pulsed-ultrasound irradiation induces the production of itaconate and attenuates inflammatory responses in macrophages2022
- Author(s)
  Yamaguchi A, Maeshige N, Ma X, Uemura M, Noguchi H, Matsuda M, Nishimura Y, Hasunuma T, Kondo H, Fujino H
- Journal Title
  
  Journal of Inflammation Research
  
  Volume: 15 Pages: 2387-2395
- DOI
  10.2147/jir.s361609
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19742, KAKENHI-PROJECT-20KK0227, KAKENHI-PROJECT-23K21864
[Journal Article] Reactive oxygen species-inducing titanium peroxide nanoparticles as promising radiosensitizers for eliminating pancreatic cancer stem cells2022
- Author(s)
  Salah Mohammed、Akasaka Hiroaki、Shimizu Yasuyuki、Morita Kenta、Nishimura Yuya、Kubota Hikaru、Kawaguchi Hiroki、Sogawa Tomomi、Mukumoto Naritoshi、Ogino Chiaki、Sasaki Ryohei
- Journal Title
  
  Journal of Experimental & Clinical Cancer Research
  
  Volume: 41 Issue: 1 Pages: 146-146
- DOI
  10.1186/s13046-022-02358-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08097, KAKENHI-PROJECT-19K08121, KAKENHI-PROJECT-19H03603, KAKENHI-PROJECT-20K06430, KAKENHI-PROJECT-20K08108, KAKENHI-PROJECT-21K07594, KAKENHI-PROJECT-21K07642, KAKENHI-PROJECT-22K07771, KAKENHI-PROJECT-20K21576, KAKENHI-PROJECT-20KK0192, KAKENHI-PROJECT-21K19910, KAKENHI-PROJECT-22K15825, KAKENHI-PROJECT-23K24287
[Journal Article] Titanium oxide nano-radiosensitizers for hydrogen peroxide delivery into cancer cells2021
- Author(s)
  Morita Kenta、Nishimura Yuya、Nakamura Satoko、Arai Yuki、Numako Chiya、Sato Kazuyoshi、Nakayama Masao、Akasaka Hiroaki、Sasaki Ryohei、Ogino Chiaki、Kondo Akihiko
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces
  
  Volume: 198 Pages: 111451-111451
- DOI
  10.1016/j.colsurfb.2020.111451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01706, KAKENHI-PROJECT-18K07752, KAKENHI-PROJECT-19K08097, KAKENHI-PROJECT-19K08121, KAKENHI-PROJECT-19H03603, KAKENHI-PROJECT-20K06430, KAKENHI-PROJECT-20K08108, KAKENHI-PROJECT-21K07594, KAKENHI-PROJECT-20K21576, KAKENHI-PROJECT-20KK0192
[Journal Article] Surgical spacer placement for proton radiotherapy in locally advanced pancreatic body and tail cancers: initial clinical results2021
- Author(s)
  Dongha Lee et al.
- Journal Title
  
  Radiation Oncology
  
  Volume: 16 Issue: 1 Pages: 1-11
- DOI
  10.1186/s13014-020-01731-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08595, KAKENHI-PROJECT-20K06430, KAKENHI-PROJECT-18K07752, KAKENHI-PROJECT-19K08097, KAKENHI-PROJECT-19H03603, KAKENHI-PROJECT-20K08108, KAKENHI-PROJECT-21K07594, KAKENHI-PROJECT-20K21576, KAKENHI-PROJECT-20KK0192
[Journal Article] A Comparative Assessment of Mechanisms and Effectiveness of Radiosensitization by Titanium Peroxide and Gold Nanoparticles2020
- Author(s)
  Hassan Mennaallah、Nakayama Masao、Salah Mohammed、Akasaka Hiroaki、Kubota Hikaru、Nakahana Makiko、Tagawa Tatsuichiro、Morita Kenta、Nakaoka Ai、Ishihara Takeaki、Miyawaki Daisuke、Yoshida Kenji、Nishimura Yuya、Ogino Chiaki、Sasaki Ryohei
- Journal Title
  
  Nanomaterials
  
  Volume: 10 Issue: 6 Pages: 1125-1125
- DOI
  10.3390/nano10061125
- NAID
  120006878579
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08121, KAKENHI-PROJECT-20K06430, KAKENHI-PROJECT-20K08108, KAKENHI-PROJECT-20K21576, KAKENHI-PROJECT-20KK0192, KAKENHI-PROJECT-19H03603, KAKENHI-PROJECT-18K07752, KAKENHI-PROJECT-19K17169
[Journal Article] In vivo tissue distribution and safety of polyacrylic acid-modified titanium peroxide nanoparticles as novel radiosensitizers2018
- Author(s)
  Morita Kenta、Suzuki Takahiro、Nishimura Yuya、Matsumoto Kazuhisa、Numako Chiya、Sato Kazuyoshi、Nakayama Masao、Sasaki Ryohei、Ogino Chiaki、Kondo Akihiko
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: - Issue: 1 Pages: 30749-30751
- DOI
  10.1016/j.jbiosc.2018.01.012
- NAID
  40021601146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15581, KAKENHI-PROJECT-16H03194, KAKENHI-PROJECT-18K07752, KAKENHI-PROJECT-16K10395, KAKENHI-PROJECT-17K16442
[Journal Article] Affibody-displaying bio-nanocapsules effective in EGFR, typical biomarker, expressed in various cancer cells2017
- Author(s)
  Yuya Nishimura, Ryosuke Ezawa, Jun Ishii, Chiaki Ogino, Akihiko Kondo
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27(2) Issue: 2 Pages: 336-341
- DOI
  10.1016/j.bmcl.2016.11.038
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21156
[Journal Article] Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo2016
- Author(s)
  Masao Nakayama, Ryohei Sasaki, Chiaki Ogino, Tsutomu Tanaka, Kenta Morita, Mitsuo Umetsu, Satoshi Ohara, Zhenquan Tan, Yuya Nishimura, Hiroaki Akasaka, Kazuyoshi Sato, Chiya Numako, Seiichi Takami, Akihiko Kondo
- Journal Title
  
  Radiat Oncol.
  
  Volume: 11(1) Issue: 1 Pages: 91-91
- DOI
  10.1186/s13014-016-0666-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05391, KAKENHI-PROJECT-15K09996, KAKENHI-PROJECT-16K10395, KAKENHI-PROJECT-16K15581, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25246013, KAKENHI-PROJECT-16H03194
[Journal Article] Characterization of titanium dioxide nanoparticles modified with polyacrylic acid and H2O2 for use as a novel Radiosensitizer,2016
- Author(s)
  Morita K, Miyazaki S, Numaki C, Ikeno S, Sasaki R, Nishimura Y, Ogino C, Kondo A,
- Journal Title
  
  Free Radical Research,
  
  Volume: 50(12) Issue: 12 Pages: 1319-1328
- DOI
  10.1080/10715762.2016.1241879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05391, KAKENHI-PROJECT-15K21156, KAKENHI-PROJECT-15K09996, KAKENHI-PROJECT-16K15581, KAKENHI-PROJECT-16H03194
[Presentation] A novel radiosensitizer of titanium peroxide nanoparticles (TiOxNPs) through continuous ROS generation2023
- Author(s)
  Ryohei Sasaki, Hiroaki Akasaka, Masao Nakayama, Yoshiko Fujita, Hikaru Kubota, Kenta Morita, Mennaallah Hassan, Mohammed Salah, Yuya Nishimura,Naritoshi Mukumoto, Takeaki Ishihara, Daisuke Miyawaki, Chiaki Ogino.
- Organizer
  American Association of Cancer Research Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0192
[Presentation] Titanium peroxides nanoparticles are promising radiosensitizers to eliminate pancreatic cancer stem cells2023
- Author(s)
  Mohammed Salah, Hiroki Kawaguchi, Hiroaki Akasaka, Yasuyuki Shimizu, Kenta Morita, Yuya Nishimura, Hikaru Kubota, Tomomi Sogawa, NaritoshiMukumoto, Chiaki Ogino, Ryohei Sasaki.
- Organizer
  American Association of Cancer Research Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0192
[Presentation] 過酸化チタンナノ粒子による免疫放射線治療増感効果の検討2020
- Author(s)
  窪田光、藤田佳子、清水康之、Mohammed Salah、岩下和真、妹尾悟史、川口弘毅、小林加奈、石原武明、宮脇大輔、吉田賢史、西村勇哉、荻野千秋、佐々木良平
- Organizer
  第33回日本放射線腫瘍学会
- Data Source
  KAKENHI-PROJECT-20KK0192
[Presentation] Less-invasive anticancer efficacy by a combination of bio-nanocapsule/liposome complex and radiation therapy2016
- Author(s)
  Yuya Nishimura, Takahiro Suzuki, Kenta Morita, Masao Nakayama, Sachiko Inubushi,　Chiya Numako, Chiaki Ogino, Ryohei Sasaki, Akihiko Kondo
- Organizer
  International Biotechnology Symposium 2016
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21156
[Presentation] Affibody提示バイオナノカプセル/リポソーム融合粒子を用いたin vivoでの抗腫瘍効果2016
- Author(s)
  西村勇哉、鈴木貴弘、森田健太、荻野千秋、近藤昭彦
- Organizer
  化学工学会　第81年会（2016）
- Place of Presentation
  関西大学　千里山キャンパス
- Year and Date
  2016-03-13
- Data Source
  KAKENHI-PROJECT-15K21156
[Presentation] HER2受容体発現細胞を標的としたDDSキャリアの抗腫瘍効果の評価2016
- Author(s)
  西村勇哉、鈴木貴弘、森田健太、荻野千秋、近藤昭彦
- Organizer
  生物工学若手研究者の集い　夏のセミナー2016
- Place of Presentation
  ホテルコンチネンタル府中（東京都府中市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-15K21156
[Presentation] Specific drug delivery for target cancer tumor using affibody-displaying bio-nanocapsule/liposome complex2015
- Author(s)
  Yuya Nishimura, Jun Ishii, Chiaki Ogino, Akihiko Kondo
- Organizer
  PACIFICHEM 2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21156

1. Ogino Chiaki (00313693)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. Sasaki Ryohei (30346267)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. 中山雅央 (60582004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. Okada Takuya (80514786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山口雅人 (10457096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 上嶋英介 (40645561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 杉本幸司 (90314476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 沼子千弥 (80284280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 赤坂浩亮 (20707161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 明石昌也 (40597168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 筧康正 (70772896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 前重伯壮 (90617838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 金沢星慶 (60744993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 重村克巳 (00457102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 北川孝一 (00822884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SATO Kazuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. NISHIMURA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 藤野英己

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 近藤浩代

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 窪田光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimura Yuya 西村 勇哉

Research Projects

Research Products

Co-Researchers

Development of treatment system for periodontal disease and oral cancer using bio-compatible titanium dioxide

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体免疫を是正・補完する骨格筋複合物理刺激装置の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel radiosensitizer with inorganic nanoparticles and antibodies assembly

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Induction of cancer stem cells in pancreatic cancer cells and their treatment with radiosensitized nanoparticlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transarterial infusion of metallic nanoparticles for radiation therapy enhancement

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of titanium peroxide nanoparticles for cancer therapy application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

in vivo applications of next-generation DDS carrier for achieving less-invasive radiation therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] A cancer treatment strategy that combines the use of inorganic/biocomplex nanoparticles with conventional radiation therapy2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 粉砕2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Skeletal myotube-derived extracellular vesicles enhance itaconate production and attenuate inflammatory responses of macrophages2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>In vivo</i> stealthified molecularly imprinted polymer nanogels incorporated with gold nanoparticles for radiation therapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pulsed-ultrasound irradiation induces the production of itaconate and attenuates inflammatory responses in macrophages2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reactive oxygen species-inducing titanium peroxide nanoparticles as promising radiosensitizers for eliminating pancreatic cancer stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Titanium oxide nano-radiosensitizers for hydrogen peroxide delivery into cancer cells2021

Author(s)

Journal Title

Nishimura Yuya 西村勇哉