Kyumoto Yukari 久本由香里

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KYUMOTO YUKARI 久本由香里

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Researcher Number	40729026
Other IDs
Affiliation (Current)	2025: 九州大学, 歯学研究院, 助教
Affiliation (based on the past Project Information) *help	2016 – 2024: 九州大学, 歯学研究院, 助教 2014 – 2015: 九州大学, 歯学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Basic Section 57010:Oral biological science-related / 0907:Oral science and related fields Except Principal Investigator Basic Section 57010:Oral biological science-related / Morphological basic dentistry
Keywords	Principal Investigator 破骨細胞 / 骨破壊 / 骨吸収 / 病的骨破壊 / IL-1β / 細胞・組織 / カテプシンK / 糖代謝 / 脂肪細胞 / RBP4 … More Except Principal Investigator … More 骨芽細胞 / 破骨細胞 / センチネルリンパ節 / 口腔がん / リンパ節線維芽細胞様細網細胞 / プロテオミクス / 免疫シナプス / 破骨細胞誘導 / 骨芽細胞表面分子 / 免疫シナプス様構造 / 骨改造開始点・場の制御 / 血管内皮細胞 / モノクローナル抗体 / 質量分析 / 膜表面分子 / 骨改造 / 環境センサー / 血管 / 骨改造制御 / 石灰化 / 骨転移 / miRNA / 細胞外小胞 / 乳癌 / 癌骨転移 Less

口腔がんの転移をもたらすリンパ節線維芽細胞様細網細胞の変異メカニズムの解明
- Principal Investigator
  
  山座孝義
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
糖尿病誘発因子を標的とした新規骨破壊制御法の開発に関する研究Principal Investigator
- Principal Investigator
  
  久本由香里
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Regulation of pathological bone destruction targeting membrane molecules expressed in pathologically activated osteoclastsPrincipal Investigator
- Principal Investigator
  
  Kyumoto-Nakamura Yukari
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  Kyushu University
Osteoblast-specific cell-surface antigen regulating recruitment of osteoclasts: Bone regeneration based on the new concept concerning the regulation of bone remodeling
- Principal Investigator
  
  Kukita Toshio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
Interaction between bone and adipose tissue and control of obesity and glucose metabolism through the secretion factors derived from osteoclastsPrincipal Investigator
- Principal Investigator
  
  Kyumoto Yukari
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
Roles of bone metastatic mammary tumor cell-derived extracellular vesicles in osteoclast differentiation and function
- Principal Investigator
  
  Uehara Norihisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University
Control of bone destruction by RBP4, an inducible factor of diabetesPrincipal Investigator
- Principal Investigator
  
  KYUMOTO YUKARI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kyushu University

All 2024 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Erythropoietin receptor signal is crucial for periodontal ligament stem cell-based tissue reconstruction in periodontal disease2024
- Author(s)
  Zakaria MHD. Fouad、Sonoda Soichiro、Kato Hiroki、Ma Lan、Uehara Norihisa、Kyumoto-Nakamura Yukari、Sharifa M. Majd、Yu Liting、Dai Lisha、Yamauchi-Tomoda Erika、Aijima Reona、Yamaza Haruyoshi、Nishimura Fusanori、Yamaza Takayoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 6719-6719
- DOI
  10.1038/s41598-024-57361-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19565, KAKENHI-PROJECT-22K10249, KAKENHI-PROJECT-21K16932, KAKENHI-PROJECT-23K27762
[Journal Article] Extracellular vesicles from deciduous pulp stem cells recover bone loss by regulating telomerase activity in an osteoporosis mouse model.2020
- Author(s)
  Sonoda S, Murata S, Nishida K, Kato H, Uehara N, Kyumoto-Nakamura Y, Yamaza H, Takahashi I, Kukita T, Yamaza T.
- Journal Title
  
  Stem Cell Res Ther
  
  Volume: 11 Issue: 1
- DOI
  10.1186/s13287-020-01818-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09506, KAKENHI-PROJECT-19K18945
[Journal Article] Acetylsalicylic Acid Treatment and Suppressive Regulation of AKT Accelerate Odontogenic Differentiation of Stem Cells from the Apical Papillla.2019
- Author(s)
  Tanaka Y, Sonoda S, Yamaza H, Murata S, Nishida K, Kyumoto-Nakamura Y, Uehara N, Nonaka K, Kukita T, Yamaza T.Tanaka Y
- Journal Title
  
  J Endod. 2019 May;45(5):591-598.e6.
  
  Volume: 45 Issue: 5 Pages: 591-598
- DOI
  10.1016/j.joen.2019.01.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09506
[Journal Article] Osteoblast lineage-specific cell-surface antigen (A7) regulates osteoclast recruitment and calcification during bone remodeling2019
- Author(s)
  Badawy Tamer、Kyumoto-Nakamura Yukari、Uehara Norihisa、Zhang Jingqi、Sonoda Soichiro、Hiura Hidenobu、Yamaza Takayoshi、Kukita Akiko、Kukita Toshio
- Journal Title
  
  Laboratory Investigation
  
  Volume: 印刷中 Issue: 6 Pages: 1-19
- DOI
  10.1038/s41374-018-0179-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09034, KAKENHI-PROJECT-18K09506, KAKENHI-PROJECT-16K10908
[Journal Article] IL-1beta induce pathologically activated osteoclasts bearing extremely high level of resorption activity imaged by pH-sensitive fluorescence probes: A possible pathological subpopulation of osteoclasts, accompanied with suppressed expression of integrin regulating molecule kindling-3 and talin-1.2018
- Author(s)
  Shiratori T., Kyumoto-Nakamura Y., Kukita A., Uehara N., Zhang J., Koda K., Kamiya M., Badawy T., Tomoda E., Xu X., Yamaza T., Urano Y., Koyano K., Kukita T.
- Journal Title
  
  J. Immunology
  
  Volume: 200 Issue: 1 Pages: 218-228
- DOI
  10.4049/jimmunol.1602035
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11046, KAKENHI-PROJECT-16K20413, KAKENHI-PROJECT-18K09034, KAKENHI-PROJECT-18K09506, KAKENHI-PROJECT-16K10908
[Journal Article] Osteoblast-derived Laminin-332 is a novel negative regulator of　osteoclastogenesis in bone microenvironments.2017
- Author(s)
  Uehara N, Kukita A, Kyumoto-Nakamura Y, Yamaza T, Yasuda H, Kukita T.
- Journal Title
  
  Lab Invest.
  
  Volume: 97 Issue: 10 Pages: 1235-1244
- DOI
  10.1038/labinvest.2017.55
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10908, KAKENHI-PROJECT-15K11014, KAKENHI-PROJECT-15K11046
[Presentation] 破骨細胞機能制御に関連する新規破骨細胞特異的膜表面抗原2020
- Author(s)
  顧炯炎,久本由香里,寺町順平,日浦秀暢,張旌旗, 張暁旭,上原範久,山座孝義,久木田明子,久木田敏夫
- Organizer
  歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18K09506
[Presentation] 骨芽細胞特異的な骨改造制御膜表面分子の同定と機能解析2020
- Author(s)
  日浦秀暢, 久本由香里, Tamer Badawy, 上原範久, 張旌旗, 顧炯炎, 山座孝義, 久木田明子, 高橋一郎, 久木田敏夫
- Organizer
  歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18K09506
[Presentation] 骨転移癌細胞―破骨細胞間コミニュケーションツールとしてのエクソソームの役割2018
- Author(s)
  上原範久, 久本由香里, 久木田明子, 久木田敏夫
- Organizer
  日本解剖学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] Osteoblast Lineage^Specific Cell Surface Antigen Regulation Osteoclastogenesis and Calcification. A Possible New Player in Bone Remodeling2018
- Author(s)
  Badawy Tamer, 久本由香里、上原範久、張旌旗、山座孝義、久木田明子、久木田敏夫
- Organizer
  第60回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-18K09506
[Presentation] Osteoblast-specific cell surface antigen regulating osteoclastogenesis and calcification. A possible unique modulator of bone remodeling2018
- Author(s)
  Tamer Badawy, Yukari Kyumoto-Nakamura, Norihisa Uehara, Akiko Kukita, Toshio Kukita
- Organizer
  American Siciety of Bone and Mineral Research (ASBMR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09506
[Presentation] Novel Osteoblast-Lineage Specific Cell-Surface Antigen Possibly Regulating Osteoclastogenesis and Calcification 破骨細胞形成と石灰化を制御する可能性を有する新規骨芽細胞膜表面抗原2018
- Author(s)
  Tamer Badawy, 久本由香里、上原範久、久木田明子、久木田敏夫
- Organizer
  第36回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18K09506
[Presentation] 破骨細胞分化制御における Galectin-9/Tim-3 シグナルの関与2018
- Author(s)
  久本由香里、上原範久、久木田明子、久木田敏夫
- Organizer
  第36回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-18K09506
[Presentation] Extracellular vesicles from bone metastatic mammary tumor cells facilitate osteoclast formation and bone resorption in vitro2017
- Author(s)
  上原範久, 久本由香里, 久木田　明子, 久木田　敏夫
- Organizer
  日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] マウス骨転移性乳癌細胞由来エクソソームは破骨細胞分化を促進する2016
- Author(s)
  上原　範久、久本由香里、久木田明子、久木田敏夫
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] 分泌型miRNAを介した骨転移性癌細胞-破骨細胞間コミュニケーション2016
- Author(s)
  上原範久、久本由香里、久木田明子、久木田敏夫
- Organizer
  日本解剖学会
- Place of Presentation
  福島
- Year and Date
  2016-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] Bone metastatic mammary tumor cell-derived extracellular vesicles as positive regulator of osteoclastogenesis2016
- Author(s)
  上原　範久、久本由香里、久木田明子、久木田敏夫
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K11014
[Presentation] Galectin-9による破骨細胞分化制御メカニズムの解明：NFATc1の発現を抑制する転写因子MafB及びIRF-8の関与2015
- Author(s)
  久本由香里、上原範久、久木田明子、久木田敏夫
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  新宿
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26893194
[Presentation] Galectin-9による破骨細胞形成抑制機構：MafB制御系関与の可能性2015
- Author(s)
  久本由香里、上原範久、久木田明子、久木田敏夫
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26893194
[Presentation] ラミニン-332によるRANK発現調節とマクロファージ-破骨細胞分化転換の制御2015
- Author(s)
  上原範久、久木田明子、久本由香里、保田尚孝、久木田敏夫
- Organizer
  第33回日本骨代謝学会学術集会
- Place of Presentation
  新宿
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26893194

1. Kukita Toshio (70150464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. 久木田明子 (30153266)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. Uehara Norihisa (30368211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 山座孝義 (80304814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 園田聡一朗 (10831985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Kyumoto Yukari 久本 由香里

KYUMOTO YUKARI 久本 由香里

Research Projects

Research Products

Co-Researchers

口腔がんの転移をもたらすリンパ節線維芽細胞様細網細胞の変異メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖尿病誘発因子を標的とした新規骨破壊制御法の開発に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of pathological bone destruction targeting membrane molecules expressed in pathologically activated osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Osteoblast-specific cell-surface antigen regulating recruitment of osteoclasts: Bone regeneration based on the new concept concerning the regulation of bone remodeling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interaction between bone and adipose tissue and control of obesity and glucose metabolism through the secretion factors derived from osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of bone metastatic mammary tumor cell-derived extracellular vesicles in osteoclast differentiation and function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Control of bone destruction by RBP4, an inducible factor of diabetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Erythropoietin receptor signal is crucial for periodontal ligament stem cell-based tissue reconstruction in periodontal disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular vesicles from deciduous pulp stem cells recover bone loss by regulating telomerase activity in an osteoporosis mouse model.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetylsalicylic Acid Treatment and Suppressive Regulation of AKT Accelerate Odontogenic Differentiation of Stem Cells from the Apical Papillla.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteoblast lineage-specific cell-surface antigen (A7) regulates osteoclast recruitment and calcification during bone remodeling2019

Author(s)

Journal Title

DOI

Data Source

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteoblast-derived Laminin-332 is a novel negative regulator of osteoclastogenesis in bone microenvironments.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 破骨細胞機能制御に関連する新規破骨細胞特異的膜表面抗原2020

Author(s)

Organizer

Data Source

Kyumoto Yukari 久本由香里

KYUMOTO YUKARI 久本由香里

[Journal Article] Osteoblast-derived Laminin-332 is a novel negative regulator of　osteoclastogenesis in bone microenvironments.2017