EDAHIRO YOKO 枝廣陽子

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Edahiro Yoko 枝廣陽子

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Researcher Number	40732863
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2020 – 2021: 順天堂大学, 医学部, 准教授 2019: 順天堂大学, 医学部, 助教 2015 – 2017: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator JAK2V617F変異 / JAK2V617F / 骨髄増殖性腫瘍 / インターフェロン / iPS細胞

Identification of the mechanism of anti-tumor effect of IFN-alpha against malignant stem cells using iPS cellsPrincipal Investigator
- Principal Investigator
  
  Edahiro Yoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Identification of a new transcriptional cascade activated by oncogenic JAK2 tyrosine kinase mutantPrincipal Investigator
- Principal Investigator
  
  EDAHIRO YOKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University

All 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 未来型血液治療学2019
- Author(s)
  小松則夫(編)　枝廣陽子他
- Total Pages
  285
- Publisher
  中外医学社
- ISBN
  9784498225183
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] Validation and reliability of current guidelines for the treatment of essential thrombocythemia under real-world clinical settings in Japan2022
- Author(s)
  Baba Terumi、Hashimoto Yoshinori、Yasuda Hajime、Araki Marito、Edahiro Yoko、Morishita Soji、Ochiai Tomonori、Shirane Shuichi、Ando Jun、Komatsu Norio
- Journal Title
  
  Hematology
  
  Volume: 27 Issue: 1 Pages: 157-166
- DOI
  10.1080/16078454.2021.2022848
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] Systemic chemotherapy combined with thrombopoietin receptor agonist for the treatment of diffuse large B-cell lymphoma complicated with aplastic anemia2022
- Author(s)
  福田泰隆、枝廣陽子、高久智生、古屋智帆、白根脩一、浜埜康晴、小池道明、小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 63 Issue: 1 Pages: 20-25
- DOI
  10.11406/rinketsu.63.20
- NAID
  130008158337
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] MPL overexpression induces a high level of mutant-CALR/MPL complex: a novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with CALR mutations2021
- Author(s)
  Yasuda Shunichiro、Aoyama Satoru、Yoshimoto Ryoto、Li Huixin、Watanabe Daisuke、Akiyama Hiroki、Yamamoto Kouhei、Fujiwara Takeo、Najima Yuho、Doki Noriko、Sakaida Emiko、Edahiro Yoko、Imai Misa、Araki Marito、Komatsu Norio、Miura Osamu、Kawamata Norihiko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 114 Issue: 4 Pages: 424-440
- DOI
  10.1007/s12185-021-03180-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871
[Journal Article] Intravascular large B-cell lymphoma as a recurrence of primary central nervous system lymphoma after chemotherapy: A case report2021
- Author(s)
  Edahiro Yoko、Takaku Tomoiku、Suzuki Mario、Fukuda Yasutaka、Harada Sakiko、Kinoshita Shintaro、Inano Tadaaki、Shirane Shuichi、Hamano Yasuharu、Kondo Akihide、Komatsu Norio
- Journal Title
  
  Leukemia Research Reports
  
  Volume: 15 Pages: 100249-100249
- DOI
  10.1016/j.lrr.2021.100249
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] Clinical characteristics, prognostic factors, and outcomes of patients with essential thrombocythemia in Japan: the JSH-MPN-R18 study2021
- Author(s)
  Hashimoto Y, Ito T, Gotoh A, Nakamae M, Kimura F, Koike M, Kirito K, Wada H, Usuki K, Tanaka T, Mori T, Wakita S, Saito TI, Kada A, Saito AM, Shimoda K, Sugimoto Y, Kurokawa T, Tomita A, Edahiro Y, Akashi K, Matsumura I, Takenaka K, Komatsu N
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 2 Pages: 208-221
- DOI
  10.1007/s12185-021-03253-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-20H03713, KAKENHI-PROJECT-21H02949, KAKENHI-PROJECT-21K08407
[Journal Article] Clinical impacts of the mutational spectrum in Japanese patients with primary myelofibrosis2021
- Author(s)
  Morishita Soji、Ochiai Tomonori、Misawa Kyohei、Osaga Satoshi、Inano Tadaaki、Fukuda Yasutaka、Edahiro Yoko、Ohsaka Akimichi、Araki Marito、Komatsu Norio
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 4 Pages: 500-507
- DOI
  10.1007/s12185-020-03054-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871
[Journal Article] Long-term spontaneous regression of Stage IV diffuse large B-cell lymphoma2021
- Author(s)
  Furukawa Yoshiki、Ando Jun、Ando Miki、Kinoshita Shintaro、Edahiro Yoko、Furuta Takuya、Ohshima Koichi、Komatsu Norio
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 61 Issue: 3 Pages: 168-172
- DOI
  10.3960/jslrt.21002
- NAID
  130008087357
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia2021
- Author(s)
  Inano Tadaaki、Araki Marito、Morishita Soji、Imai Misa、Kihara Yoshihiko、Okuda Maho、Yang Yinjie、Ito Masafumi、Osaga Satoshi、Mano Hiroyuki、Edahiro Yoko、Ochiai Tomonori、Misawa Kyohei、Fukuda Yasutaka、Ando Jun、Komatsu Norio
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 17702-17702
- DOI
  10.1038/s41598-021-97106-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-21K16250, KAKENHI-PROJECT-21K16275
[Journal Article] Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin2020
- Author(s)
  Edahiro Yoko、Araki Marito、Komatsu Norio
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 8 Pages: 2682-2688
- DOI
  10.1111/cas.14503
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848
[Journal Article] Interferon therapy for pregnant patients with essential thrombocythemia in Japan2020
- Author(s)
  Edahiro Yoko、Yasuda Hajime、Gotoh Akihiko、Morishita Soji、Suzuki Toshifumi、Takeda Jun、Ando Jun、Tsutsui Miyuki、Itakura Atsuo、Komatsu Norio
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 1 Pages: 106-111
- DOI
  10.1007/s12185-020-03001-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-18K08372
[Journal Article] Difficulty Diagnosing a Brain Tumor during Clinical Maintenance of a Complete Response to anti-HER2 Treatments for Metastatic Breast Cancer: A Case Report2020
- Author(s)
  Ryoko Semba, Yoshiya Horimoto, Atsushi Arakawa, Yoko Edahiro, Tomoiku Takaku, Kotaro Iijima, Mitsue Saito
- Journal Title
  
  Case Reports in Oncology
  
  Volume: Sep-Dec;13(3) Issue: 3 Pages: 1311-1316
- DOI
  10.1159/000511051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07684, KAKENHI-PROJECT-19K17871
[Journal Article] CREB3L1 overexpression as a potential diagnostic marker of Philadelphia chromosome?negative myeloproliferative neoplasms2020
- Author(s)
  Morishita Soji、Yasuda Hajime、Yamawaki Saya、Kawaji Hideya、Itoh Masayoshi、Edahiro Yoko、Imai Misa、Kogo Yasushi、Tsuneda Satoshi、Ohsaka Akimichi、Hayashizaki Yoshihide、Ito Masafumi、Araki Marito、Komatsu Norio
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 2 Pages: 884-892
- DOI
  10.1111/cas.14763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-20H03715, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848
[Journal Article] Recent advances in polycythemia vera treatment2020
- Author(s)
  枝廣陽子
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 9 Pages: 1187-1194
- DOI
  10.11406/rinketsu.61.1187
- NAID
  130007937077
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] Specific mechanisms of subarachnoid hemorrhage accompanied by ischemic stroke in essential thrombocythemia: two case reports and a literature review2019
- Author(s)
  Sugiyama Mizuho、Ueno Yuji、Kamo Hikaru、Edahiro Yoko、Miyamoto Nobukazu、Yamashiro Kazuo、Tanaka Ryota、Shimo Yasushi、Komatsu Norio、Hattori Nobutaka
- Journal Title
  
  Journal of Neurology
  
  Volume: 266 Issue: 8 Pages: 1869-1878
- DOI
  10.1007/s00415-019-09347-4
- Data Source
  KAKENHI-PROJECT-19K17871
[Journal Article] Evidence for prevention of renal dysfunction associated with primary myelofibrosis by cytoreductive therapy2019
- Author(s)
  Fukuda Yasutaka、Araki Marito、Yamamoto Kouji、Morishita Soji、Inano Tadaaki、Misawa Kyohei、Ochiai Tomonori、Edahiro Yoko、Imai Misa、Yasuda Hajime、Gotoh Akihiko、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  Haematologica
  
  Volume: 印刷中 Issue: 11 Pages: e506-e509
- DOI
  10.3324/haematol.2018.208876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-17K16195
[Journal Article] Mutant calreticulin interacts with MPL in the secretion pathway for activation on the cell surface2019
- Author(s)
  Masubuchi Nami、Araki Marito、Yang Yinjie、Hayashi Erina、Imai Misa、Edahiro Yoko、Hironaka Yumi、Mizukami Yoshihisa、Kihara Yoshihiko、Takei Hiraku、Nudejima Mai、Koike Masato、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  Leukemia
  
  Volume: 34 Issue: 2 Pages: 499-509
- DOI
  10.1038/s41375-019-0564-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-18K16098, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-18K16126
[Journal Article] Efficacy and safety of ruxolitinib in patients with myelofibrosis: a single-center retrospective analysis2019
- Author(s)
  枝廣陽子、小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 7 Pages: 755-760
- DOI
  10.11406/rinketsu.60.755
- NAID
  130007688020
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871
[Journal Article] Clinical and molecular features of patients with prefibrotic primary myelofibrosis previously diagnosed as having essential thrombocythemia in Japan2019
- Author(s)
  Edahiro Yoko、Araki Marito、Inano Tadaaki、Ito Masafumi、Morishita Soji、Misawa Kyohei、Fukuda Yasutaka、Imai Misa、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  European Journal of Haematology
  
  Volume: 00 Issue: 6 Pages: 1-5
- DOI
  10.1111/ejh.13236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19203, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871
[Journal Article] JAK2 exon 12 mutation in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis: Not an exclusive mutation to polycythaemia vera2019
- Author(s)
  Inano, T. Araki, M. Morishita, S. Imai, M. Yasuda, H. Nitta, H. Ito, M. Edahiro, Y. Ochiai, T. Misawa, K. Fukuda, Y. Ohsaka, A. Komatsu, N.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 187 Issue: 1
- DOI
  10.1111/bjh.16146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-17K16195
[Journal Article] The 2014 BCSH criteria and the 2016 WHO criteria for essential thrombocythemia: A comparison in a large-scale cohort.2018
- Author(s)
  Ochiai T, Yasuda H, Araki M, Misawa K, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
- Journal Title
  
  Eur J Haematol
  
  Volume: 印刷中 Issue: 6 Pages: 544-549
- DOI
  10.1111/ejh.13041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K19559, KAKENHI-PROJECT-18K06690
[Journal Article] utational subtypes of JAK2 and CALR correlate with different clinical features in Japanese patients with myeloproliferative neoplasms.2018
- Author(s)
  3.Misawa K, Yasuda H, Araki M, Ochiai T, Morishita S, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
- Journal Title
  
  International journal of hematology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19559
[Journal Article] 本態性血小板血症治療の現状と今後2017
- Author(s)
  枝廣陽子、小松則夫.
- Journal Title
  
  血液フロンティア
  
  Volume: 1 Pages: 134-140
- Data Source
  KAKENHI-PROJECT-15K19559
[Journal Article] The 2016 WHO diagnostic criteria for polycythemia vera renders an accurate diagnosis to a broader range of patients including masked polycythemia vera: Comparison with the 2008 WHO diagnostic criteria.2017
- Author(s)
  Misawa K, Yasuda H, Araki M, Ochiai T, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
- Journal Title
  
  Am J Hematol
  
  Volume: 92 Issue: 7
- DOI
  10.1002/ajh.24752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K19559
[Journal Article] Hydroxycarbamide投与中に急激な胸水貯留を来した骨髄線維化を伴う慢性骨髄単球性白血病.2016
- Author(s)
  角南義孝、後藤明彦、渡邊直紀、枝廣陽子、浜埜康晴、原田浩徳、小松則夫.
- Journal Title
  
  癌と化学療法
  
  Volume: 43 Pages: 1223-1226
- Data Source
  KAKENHI-PROJECT-15K19559
[Journal Article] Identification of AIM2 as a downstream target of JAK2V617F.2016
- Author(s)
  Liew EL, Araki M, Hironaka Y, Mori S, Tan TZ, Morishita S, Edahiro Y, Ohsaka A, Komatsu N.
- Journal Title
  
  Exp Hematol Oncol.
  
  Volume: 5 Issue: 1 Pages: 2-2
- DOI
  10.1186/s40164-016-0032-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06861, KAKENHI-PROJECT-15K19559
[Journal Article] Co-occurrence of hyperleukocytosis and elevated fibrin-fibrinogen degradation product levels is a risk factor for early intracranial hemorrhage in patients with de novo acute leukemia.2016
- Author(s)
  Ichikawa K, Edahiro Y, Gotoh A, Iiduka K, Komatsu N, Koike M.
- Journal Title
  
  Int J Hematol.
  
  Volume: 104 Issue: 5 Pages: 612-620
- DOI
  10.1007/s12185-016-2072-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19559
[Journal Article] Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms.2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N
- Journal Title
  
  Blood
  
  Volume: 127 Issue: 10 Pages: 1307-16
- DOI
  10.1182/blood-2015-09-671172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-15K19559, KAKENHI-PROJECT-26893264
[Journal Article] Safe and effective induction therapy with CHASER for primary testicular lymphoma with central nervous system involvement.2016
- Author(s)
  Sunami Y, Ichikawa K, Edahiro Y, Komatsu N, Koike M.
- Journal Title
  
  Int J Clin Exp Med
  
  Volume: 9 Pages: 18645-18649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19559
[Journal Article] Current problems in the diagnosis of Philadelphia-negative myeloproliferative neoplasms in Japan2015
- Author(s)
  白根脩一、荒木真理人、森下総司、枝廣陽子、大阪顯通、小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 7 Pages: 877-882
- DOI
  10.11406/rinketsu.56.877
- NAID
  130005093120
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-15K19559
[Journal Article] Application of genetic data to clinical practice of MPN2015
- Author(s)
  Edahiro Y
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 8 Pages: 949-955
- DOI
  10.11406/rinketsu.56.949
- NAID
  130005096294
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Absence of JAK2 mutation excludes polycythemia vera2021
- Author(s)
  森洋輔, 荒木真理人, 森下総司, 今井美沙, 枝廣陽子, 伊藤雅文, 落合友則, 白根脩一, 橋本由徳, 安藤純, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Distributions of typical non-driver mutations in essential thrombocythemia and polycythemia vera2021
- Author(s)
  森下総司、枝廣陽子、橋本由徳、白根脩一、落合友則、三澤恭平、稲野資明、福田泰隆、森洋輔、古屋智帆、荒木真理人、安藤純、小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Quantitative measurement of mutant calreticulin in specimens of myeloproliferative neoplasm patients2021
- Author(s)
  尾形智子, 荒木真理人, 木原慶彦, 奥田真帆, 森下総司, 今井美沙, 増渕菜弥, 森洋輔, Yinjie Yang, 吉川隼平, 落合友則, 白根脩一, 枝廣陽子, 安藤純, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Diversity of thrombosis event-free survival by the treatment in essential thrombocythemia patients2021
- Author(s)
  馬場照美, 橋本由徳, 荒木真理人, 安田肇, 枝廣陽子, 森下総司, 落合友則, 白根脩一, 安藤純, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Specific expression of CREB3L1 in megakaryocyte in myeloproliferative neoplasms2021
- Author(s)
  奥田真帆, 荒木真理人, Federico Demarchi, 森下総司, 今井美沙, 森洋輔, 堀野芽生, 落合友則, 白根脩一, 枝廣陽子, 安藤純, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Clinical characteristics of Japanese patients with polycythemia vera: JSH MPN-R18 study results2021
- Author(s)
  枝廣陽子, 橋本由徳, 伊藤量基, 後藤明彦, 中前美佳, 木村文彦, 小池道明, 桐戸敬太, 和田秀穂, 臼杵憲祐, 田中孝幸, 森毅彦, 脇田知志, 齋藤俊樹, 嘉田晃子, 齋藤明子, 下田和哉, 杉本由香, 黒川敏郎, 冨田章裕, 赤司浩一, 松村到, 竹中克斗, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] A nationwide survey on Japanese patients with essential thrombocythemia: JSH-MPN-R18 study2021
- Author(s)
  橋本由徳, 枝廣陽子, 伊藤量基, 後藤明彦, 中前美佳, 木村文彦, 小池道明, 桐戸敬太, 和田秀穂, 臼杵憲祐, 田中孝幸, 森毅彦, 脇田知志, 齋藤俊樹, 嘉田晃子, 齋藤明子, 下田和哉, 杉本由香, 黒川敏郎, 冨田章裕, 赤司浩一, 松村到, 竹中克斗, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Clinical presentation of thrombocytosis: A single-center retrospective study of 1202 patients2021
- Author(s)
  枝廣陽子, 黒川安満, 森下総司, 荒木真理人, 安藤純, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] CREB3L1 overexpression as a novel diagnostic marker of myeloproliferative neoplasms2020
- Author(s)
  Soji Morishita，Hajime Yasuda，Saya Yamawaki，Hideya Kawaji， Masayoshi Itoh，Yoko Edahiro，Misa Imai，Yasushi Kogo，Satoshi Tsuneda，Akimichi Ohsaka，Yoshihide Hayashizaki，Marito Araki，Norio Komatsu
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] MPL overexpression induces a high level of mutant-Calr/MPL complex: A novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with Calr mutations.2020
- Author(s)
  Shunichiro Yasuda, Satoru Aoyama, Ryoto Yoshimoto, Daisuke Watanabe, Hiroki Akiyama, Kouhei Yamamoto, Takeo Fujiwara, Emiko Sakaida, Yoko Edahiro, Misa Imai, Marito Araki, Norio Komatsu, Norihiko Kawamata.
- Organizer
  62nd ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Two cases of R-CHOP therapy combined with eltrombopag for treatment DLBCL complicated with AA2020
- Author(s)
  Yasutaka Fukuda, Tomoiku Takaku, Chiho Furuya, Shuichi Shiran, Yoko Edahiro, Yasuharu Hamano, Norio Komatsu
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Overexpression of MPL causes ruxolitinib-resistance in MPN with CALR frame-shift mutations2020
- Author(s)
  Shunichiro Yasuda，Satoru Aoyama，Ryoto Yoshimoto，Daisuke Watanabe，Kouhei Yamamoto，Takeo Fujiwara，Yoko Edahiro， Misa Imai，Marito Araki，Norio Komatsu，Osamu Miura，Norihiko Kawamata
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] 第82回日本血液学会学術集会2020
- Author(s)
  Yoko Edahiro, Tomoiku Takaku, Yasutaka Fukuda, Sakiko Harada, Shintaro Kinoshita, Tadaaki Inano, Shuichi Shirane, Yasuharu Hamano, Norio Komatsu
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] PV治療の最前線2020
- Author(s)
  枝廣陽子
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] 変異型CALRはMPLと分泌経路で相互作用し細胞表面で活性化を引き起こす2019
- Author(s)
  増渕菜弥, 荒木真理人, 楊印杰, 林英里奈, 今井美沙, 枝廣陽子, 弘中由美, 水上喜久, 木原慶彦, 小池正人, 大坂顯通, 小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] 真性トリプルネガティブ本態性血小板血症における臨床的・分子生物学的特異性2019
- Author(s)
  稲野資明、荒木真理人、森下総司、落合友則、三澤恭平、福田泰隆、緑川直子、橳島麻衣、伊藤雅文、大佐賀智、枝廣陽子、今井美沙、田口鉄平、奥田真帆、大坂顯通、小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Characteristics of juvenile essential thrombocythemia2019
- Author(s)
  枝廣陽子、森下総司、稲野資明、福田泰隆、黒川安満、森洋輔、大坂顯通、荒木真理人、小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] MPL高発現がCALR変異陽性骨髄増殖性疾患におけるロキソリチニブ耐性のメカニズムである。2019
- Author(s)
  安田峻一郎、青山慧、吉本龍人、渡邉大介、山本浩平、枝廣陽子、荒木真理人、小松則夫、三浦修、川俣紀彦
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Polycythemia vera complicated with paraneoplastic vasculitis2019
- Author(s)
  福田泰隆、枝廣陽子、森下総司、筒井深雪、新田英昭、安藤純、荒木真理人、小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] The frequency of JAK2 V617F mutation in patients with myocardial or cerebral infarction2019
- Author(s)
  筒井深雪、森下総司、西野隆、枝廣陽子、常田聡、荒木真理人、大坂顯通、小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] The impact of allelic burden of JAK2V617F on human hematopoietic cell differentiation.2019
- Author(s)
  枝廣陽子, 竹井拓, Liu Chang, 橳島麻衣, 森下総司, 大坂顯通, 荒木真理人, 小松則夫
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] Correction of JAK2 V617F mutation in PV-derived iPSCs2019
- Author(s)
  枝廣陽子、劉暢、荒木真理人、橳島麻衣、森下総司、今井美沙、増渕菜弥、水上喜久、眞野修一、竹井拓、大坂顯通、小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] 分泌経路における変異型分子シャペロンとサイトカイン受容体の会合による細胞の腫瘍化2019
- Author(s)
  増渕菜弥, 荒木真理人, 木原慶彦, 楊印杰, 今井美沙, 水上喜久, 林英里奈, 弘中由美, 竹井拓, 枝廣陽子, 大坂顯通, 小松則夫
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17871
[Presentation] 変異型CALR タンパク質の発現を制御するメカニズム.2017
- Author(s)
  木原慶彦、荒木真理人、楊印杰、今井美沙、増渕菜弥、水上喜久、弘中由美、竹井拓、枝廣陽子、大坂顯通、小松則夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] 変異型CALR による巨核球分化偏向性はGATA2の発現亢進と相関している.2017
- Author(s)
  竹井拓、眞野修一、増渕菜弥、水上喜久、今井美沙、森下総司、枝廣陽子、弘中由美、橳島麻衣、遠藤大、中村壮、江藤浩之、大坂顯通、荒木真理人、小松則夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] ESTABLISHMENT OF AN IN VITRO MODEL FOR THE SKEWED MEGAKARYOPOIESIS BY CALRETICULIN MUTATION IN HUMAN CELLS2017
- Author(s)
  Hiraku Takei, Shuichi Mano, Nami Masubuchi, Yoshihisa Mizukami, Soji Morishita, Misa Imai, Yoko Edahiro, Yumi Hironaka, Mai Nudejima, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu.
- Organizer
  22nd Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] 骨髄増殖性腫瘍に見出される変異型CALR 蛋白質の細胞内局在.2017
- Author(s)
  林英里奈、荒木真理人、増渕菜弥、水上喜久、楊印杰、今井美沙、弘中由美、竹井拓、木原慶彦枝廣陽子大坂顯通、小松則夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Engagement of mutant calreticulin and MPL in acellular compartment is required for MPL activation.2017
- Author(s)
  増渕菜弥、荒木真理人、林英里奈、楊印杰、今井美沙、水上喜久、弘中由美、竹井拓、森下総司、木原慶彦、枝廣陽子、大坂顯通、小松則夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Localization of Mutant Calreticulin in the Golgi Apparatus Is Required for Its Oncogenic Capacity. 59th Annual Meeting of the American Society of Hematology.2017
- Author(s)
  Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai, Yoshihiko Kihara, Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu.
- Organizer
  59th Annual Meeting of the American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Clinical characteristics of BCSH criteria defined PV and ET patients in Japan.2016
- Author(s)
  落合友則、荒木真理人、三澤恭平、森下総司、橳島麻衣、弘中由美、白根脩一、枝廣陽子、角南義孝、後藤明彦、大坂顯通、小松則夫.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  横浜、神奈川県、日本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms.2016
- Author(s)
  Marito Araki, Yinjie Yang, Nami Masubuchi, Yumi Hironaka, Hiraku Takei, Soji Morishita, Yoshihisa Mizukami, Shin Kan, Shuichi Shirane, Yoko Edahiro, Yoshitaka Sunami, Akimichi Ohsaka, Norio Komatsu.
- Organizer
  21st Congress of European Hematology Association
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Modeling MPN phenotypes in vitro by using iPSC harboring CALR ins5 mutation.2016
- Author(s)
  竹井拓、増渕菜弥、眞野修一、荒木真理人、森下総司、水上喜久、カンシン、枝廣陽子、角南義孝、弘中由美、遠藤大、中村壮、江藤浩之、大坂顯通、小松則夫.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  横浜、神奈川県、日本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Differential clinical features by subtypes of Calreticulin mutation in myeloproliferative neoplasms.2016
- Author(s)
  三澤恭平、荒木真理人、落合友則、森下総司、橳島麻衣、弘中由美、白根脩一、枝廣陽子、角南義孝、後藤明彦、大坂顯通、小松則夫.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  横浜、神奈川県、日本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Mutant calreticulin activates the thrombopoietin receptor in myeloproliferative neoplasms2016
- Author(s)
  荒木真理人、楊印杰、増渕菜弥、弘中由美、竹井拓、森下総司、水上喜久、カンシン、白根脩一、枝廣陽子、角南義孝、大坂顯通、小松則夫.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  横浜、神奈川県、日本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Activation of AP-1 by JAK2V617F through induction and stabilization of c-Fos2015
- Author(s)
  Edahiro Y, Araki M, Hironaka Y, Yang Y, Morishita Y, Sunami Y, Ohsaka A, Komatsu N
- Organizer
  57th Annual Meeting of the American Society of Hematology
- Place of Presentation
  Orlando FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Establishment of iPS cells from myeloproliferative neoplasms patients with CALR mutation.2015
- Author(s)
  Takei H, Morishita S, Araki M, Mizukami Y, Edahiro Y, Sunami Y, Hironaka Y, Tsumura M, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Komatsu N.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢、石川県、日本
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] Early disease onset of patients with triple-negative myeloproliferative neoplasms2015
- Author(s)
  Shirane S, Araki M, Morishita S, Edahiro Y, Takei H, Tsumura M, Hironaka Y, Ochiai T, Misawa K, Ohsaka A, Komatsu N
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢、石川県、日本
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K19559
[Presentation] A highly specific method for detecting a single copy JAK2V617F mutation2015
- Author(s)
  Morishita S, Araki M, Hironaka Y, Sunami Y, Edahiro Y, Tsutsui M, Ohsaka A, Komatsu N
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢、石川県、日本
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K19559

1. ARAKI Marito

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
2. 小松則夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
3. 後藤明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
4. 森誠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 森下総司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

EDAHIRO YOKO 枝廣 陽子

Edahiro Yoko 枝廣 陽子

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Co-Researchers

Identification of the mechanism of anti-tumor effect of IFN-alpha against malignant stem cells using iPS cellsPrincipal Investigator

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Identification of a new transcriptional cascade activated by oncogenic JAK2 tyrosine kinase mutantPrincipal Investigator

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[Book] 未来型血液治療学2019

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[Journal Article] Validation and reliability of current guidelines for the treatment of essential thrombocythemia under real-world clinical settings in Japan2022

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[Journal Article] Systemic chemotherapy combined with thrombopoietin receptor agonist for the treatment of diffuse large B-cell lymphoma complicated with aplastic anemia2022

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[Journal Article] MPL overexpression induces a high level of mutant-CALR/MPL complex: a novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with CALR mutations2021

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[Journal Article] Intravascular large B-cell lymphoma as a recurrence of primary central nervous system lymphoma after chemotherapy: A case report2021

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[Journal Article] Clinical characteristics, prognostic factors, and outcomes of patients with essential thrombocythemia in Japan: the JSH-MPN-R18 study2021

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[Journal Article] Clinical impacts of the mutational spectrum in Japanese patients with primary myelofibrosis2021

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[Journal Article] Long-term spontaneous regression of Stage IV diffuse large B-cell lymphoma2021

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[Journal Article] Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia2021

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[Journal Article] Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin2020

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[Journal Article] Interferon therapy for pregnant patients with essential thrombocythemia in Japan2020

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[Journal Article] Difficulty Diagnosing a Brain Tumor during Clinical Maintenance of a Complete Response to anti-HER2 Treatments for Metastatic Breast Cancer: A Case Report2020

EDAHIRO YOKO 枝廣陽子

Edahiro Yoko 枝廣陽子