Ishikawa Kaori 石川香

… Alternative Names

ISHIKAWA Kaori 石川香

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Researcher Number	40734827
Other IDs
Affiliation (Current)	2025: 筑波大学, 生命環境系, 准教授
Affiliation (based on the past Project Information) *help	2024: 筑波大学, 生命環境系, 准教授 2015 – 2023: 筑波大学, 生命環境系, 助教 2014 – 2015: 筑波大学, 生命環境科学研究科(系), 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Biological Sciences / Basic Section 44010:Cell biology-related / Cell biology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator ミトコンドリア / モデルマウス / 配偶子形成 / 生殖系列 / 卵胞 / 変異型mtDNA / mtDNA / ミトコンドリア・ダイナミクス / ミトコンドリアDNA / 淘汰 … More / 消失 / 突然変異 / 卵成熟 / 卵形成 / 突然変異型mtDNA / 配偶子インテグリティ / Mfn2 / 神経変性疾患モデル / 運動障害 / 認知機能 / 行動異常 / ミトコンドリアダイナミクス / Tet-off / 誘導発現 / 神経変性 / 病態モデル / 神経変性疾患 / MFN2 / Mitophagy / ΔmtDNA / 血球分化 / 貧血 / 呼吸機能 / 病態発症機構 / ミトコンドリア病 / ミトコンドリア分裂 / Drp1 … More Except Principal Investigator 分裂 / 輸送 / 微生物 / 内部共生 / 寄生 / 嫌気 / ミトコンドリア / オルガネラ / 共生 / 進化 Less

Inheritance of mitochondrial genome for the next generationPrincipal Investigator
- Principal Investigator
  
  石川香
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  University of Tsukuba
Studies on mechanisms of age-dependent disappearance of mutant mitochondrial DNA from germ line cellsPrincipal Investigator
- Principal Investigator
  
  石川香
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Elucidation of mechanisms of neurodegeneration by reversible regulation of mitochondrial dynamicsPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Kaori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  University of Tsukuba
An approach from crosstalks of nuclei-mitochondria to disease mechanisms of mitochondrial diseasesPrincipal Investigator
- Principal Investigator
  
  Ishikawa Kaori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  University of Tsukuba
Multidirectional evolution of mitochondria
- Principal Investigator
  
  Nozaki Tomoyoshi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012

All Journal Article Presentation

[Journal Article] Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment2024
- Author(s)
  Hideo Hagihara、Takao Keizo、他129名
- Journal Title
  
  eLife
  
  Volume: 12 Pages: 89376-89376
- DOI
  10.7554/elife.89376
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17422, KAKENHI-PROJECT-21K19314, KAKENHI-PROJECT-23K18168, KAKENHI-PROJECT-22K06493, KAKENHI-PROJECT-23K05612, KAKENHI-PROJECT-23K05860, KAKENHI-PROJECT-23K06119, KAKENHI-PROJECT-23K06338, KAKENHI-PROJECT-23K06399, KAKENHI-PROJECT-22K19281, KAKENHI-PROJECT-18K15457, KAKENHI-PROJECT-18H04016, KAKENHI-PROJECT-20H00491, KAKENHI-PROJECT-20H00492, KAKENHI-PLANNED-20H05895, KAKENHI-PUBLICLY-22H05614, KAKENHI-PUBLICLY-23H04227, KAKENHI-PLANNED-23H04951, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-23K21457, KAKENHI-PROJECT-23K23801, KAKENHI-PROJECT-23K23816, KAKENHI-PROJECT-23K27324
[Journal Article] Pearson syndrome-like anemia induced by accumulation of mutant mtDNA and anemia with imbalanced white blood cell lineages induced by Drp1 deletion in a murine model2022
- Author(s)
  Ishikawa Kaori、Honma Yo、Yoshimi Ayami、Katada Shun、Ishihara Takaya、Ishihara Naotada、Nakada Kazuto
- Journal Title
  
  Pharmacological Research
  
  Volume: 185 Pages: 106467-106467
- DOI
  10.1016/j.phrs.2022.106467
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06066, KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-23K23801
[Journal Article] Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation2022
- Author(s)
  Tani Haruna、Ishikawa Kaori、Tamashiro Hiroaki、Ogasawara Emi、Yasukawa Takehiro、Matsuda Shigeru、Shimizu Akinori、Kang Dongchon、Hayashi Jun-Ichi、Wei Fan-Yan、Nakada Kazuto
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 16 Pages: 9382-9396
- DOI
  10.1093/nar/gkac699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07127, KAKENHI-PLANNED-21H05265, KAKENHI-PROJECT-22KJ0156, KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-23K21370, KAKENHI-PROJECT-23K23801
[Journal Article] Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease2021
- Author(s)
  Ishikawa Kaori、Nakada Kazuto
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1865 Issue: 3 Pages: 129835-129835
- DOI
  10.1016/j.bbagen.2020.129835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06203
[Journal Article] A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome2021
- Author(s)
  Kishita Yoshihito、Ishikawa Kaori、Nakada Kazuto、Hayashi Jun-Ichi、Fushimi Takuya、Shimura Masaru、Kohda Masakazu、Ohtake Akira、Murayama Kei、Okazaki Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11123-11123
- DOI
  10.1038/s41598-021-90196-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-19H03141, KAKENHI-PROJECT-19H03624
[Journal Article] Neuronal degeneration and cognitive impairment can be prevented via the normalization of mitochondrial dynamics2021
- Author(s)
  Ishikawa Kaori、Yamamoto Satoshi、Hattori Satoko、Nishimura Naoya、Matsumoto Hirokazu、Miyakawa Tsuyoshi、Nakada Kazuto
- Journal Title
  
  Pharmacological Research
  
  Volume: 163 Pages: 105246-105246
- DOI
  10.1016/j.phrs.2020.105246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H06276
[Journal Article] Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells2021
- Author(s)
  Horibe Sayo、Ishikawa Kaori、Nakada Kazuto、Wake Masaki、Takeda Norihiko、Tanaka Toru、Kawauchi Shoji、Sasaki Naoto、Rikitake Yoshiyuki
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 2 Pages: 32-32
- DOI
  10.3892/or.2021.8243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-20K07169
[Journal Article] Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK‐448, for its anti‐tumor efficacy in a rat xenograft model2020
- Author(s)
  Kogame Akifumi、Ishikawa Kaori、DeJongh Joost、Tagawa Yoshihiko、Matsui Hisanori、Moriya Yuu、Kondo Takahiro、Asahi Satoru
- Journal Title
  
  Biopharmaceutics & Drug Disposition
  
  Volume: 41 Issue: 7 Pages: 283-294
- DOI
  10.1002/bdd.2245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06203
[Journal Article] Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells.2019
- Author(s)
  Ishikawa K, Kobayashi K, Yamada A, Umehara M, Oka T, Nakada K.
- Journal Title
  
  PLoS ONE
  
  Volume: 14 Issue: 3 Pages: 0213283-0213283
- DOI
  10.1371/journal.pone.0213283
- NAID
  120007133505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-17H03676, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-18K06203
[Journal Article] Acquired expression of mutant Mitofusin 2 causes progressive neurodegeneration and abnormal behavior2019
- Author(s)
  Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, Matsumoto H, Miyakawa T, Nakada K
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 39 Issue: 9 Pages: 1588-1604
- DOI
  10.1523/jneurosci.2139-18.2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18J20289, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06203
[Journal Article] Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders2019
- Author(s)
  Tani Haruna、Mito Takayuki、Velagapudi Vidya、Ishikawa Kaori、Umehara Moe、Nakada Kazuto、Suomalainen Anu、Hayashi Jun-Ichi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 16054-16054
- DOI
  10.1038/s41598-019-52372-6
- NAID
  120007132907
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-19H03141, KAKENHI-PROJECT-18J20289
[Journal Article] Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal.2018
- Author(s)
  Tani H, Ohnishi S, Shitara H, Mito T, Yamaguchi M, Yonekawa H, Hashizume O, Ishikawa K, Nakada K, Hayashi JI.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 425-425
- DOI
  10.1038/s41598-017-18828-3
- NAID
  120007134501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16K19034, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-16H04688, KAKENHI-PROJECT-18J20289
[Journal Article] Mito-mice∆ and mitochondrial DNA mutator mice as models of human osteoporosis caused not by aging but by hyperparathyroidism2018
- Author(s)
  Mito Takayuki、Tani Haruna、Suzuki Michiko、Ishikawa Kaori、Nakada Kazuto、Hayashi Jun-Ichi
- Journal Title
  
  Exp. Anim.
  
  Volume: 67 Issue: 4 Pages: 509-516
- DOI
  10.1538/expanim.18-0060
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-18J20289, KAKENHI-PROJECT-16K18535
[Journal Article] Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model.2018
- Author(s)
  Ishikawa K, Tanaka A, Kogame A, Watanabe T, Tagawa Y, Matsui H.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 828 Pages: 126-134
- DOI
  10.1016/j.ejphar.2018.03.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18535
[Journal Article] Cytoplasmic transfer of heritable elements other than mtDNA from SAMP1 mice into mouse tumor cells suppresses their ability to form tumors in C57BL6 mice2017
- Author(s)
  Shimizu Akinori、Tani Haruna、Takibuchi Gaku、Ishikawa Kaori、Sakurazawa Ryota、Inoue Takafumi、Hashimoto Tetsuo、Nakada Kazuto、Takenaga Keizo、Hayashi Jun-Ichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 493 Issue: 1 Pages: 252-257
- DOI
  10.1016/j.bbrc.2017.09.035
- NAID
  120007134703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-16K18535
[Journal Article] An administration of TAK-683 at a minimally effective dose for luteinizing hormone stimulation under the absence of the ovary induces luteinizing hormone surge in ovary-intact goats2017
- Author(s)
  Kanai N, Endo N, Ohkura S, Wakabayashi Y, Matsui H, Matsumoto H, Ishikawa K, Tanaka A, Watanabe T, Okamura H, Tanaka T.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 63 Issue: 3 Pages: 305-310
- DOI
  10.1262/jrd.2016-184
- NAID
  130007314605
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18535
[Journal Article] Mutations in mitochondrial DNA regulate mitochondrial diseases and metastasis but do not regulate aging.2016
- Author(s)
  Hayashi JI, Hashizume O, Ishikawa K, Shimizu A.
- Journal Title
  
  Curr Opin Genet Dev.
  
  Volume: 未定 Pages: 63-67
- DOI
  10.1016/j.gde.2016.03.004
- NAID
  120007135211
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16K19034
[Journal Article] A novel mutation in TAZ causes mitochondrial respiratory chain disorder without cardiomyopathy2016
- Author(s)
  Borna NN, Kishita Y, Ishikawa K, Nakada K, Hayashi JI, Tokuzawa Y, Kohda M, Nyuzuki H, Yamashita-Sugahara Y, Nasu T, Takeda A, Murayama K, Ohtake A, Okazaki Y
- Journal Title
  
  J Hum Genet
  
  Volume: 62 Issue: 5 Pages: 539-547
- DOI
  10.1038/jhg.2016.165
- NAID
  40021210340
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-16K09973, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16H02463, KAKENHI-PROJECT-15K09679
[Journal Article] Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects2015
- Author(s)
  Hashizume O, Ohnishi S, Mito T, Shimizu A, Ishikawa K, Nakada K, Soda M, Mano H, Togayachi S, Miyoshi H, Okita K, Hayashi J
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 10434-10434
- DOI
  10.1038/srep10434
- NAID
  120005819481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461155, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-15H06367, KAKENHI-PROJECT-14J00467
[Journal Article] Transmitochondrial mito-miceΔ and mtDNA mutator mice, but not aged mice, share the same spectrum of musculoskeletal disorders.2015
- Author(s)
  Mito T, Ishizaki H, Suzuki M, Morishima H, Ota A, Ishikawa K, Nakada K, Maeno A, Shiroishi T, Hayashi J-I
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 456 Issue: 4 Pages: 933-937
- DOI
  10.1016/j.bbrc.2014.12.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J00467, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011
[Journal Article] G7731A mutation in mouse mitochondrial tRNALys regulates late-onset disorders in transmitochondrial mice.2015
- Author(s)
  Shimizu A, Mito T, Hashizume O, Yonekawa H, Ishikawa K, Nakada K, Hayashi J-I
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Issue: 1 Pages: 66-70
- DOI
  10.1016/j.bbrc.2015.02.070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J00467, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-25640057, KAKENHI-PROJECT-25290038
[Journal Article] Mouse somatic mutation orthologous to MELAS A3302G mutation in the mitochondrial tRNA(Leu(UUR)) gene confers respiration defects.2015
- Author(s)
  Shimizu A, Enoki S, Ishikawa K, Mito T, Obata K, Nagashima R, Yonekawa H, Nakada K, Hayashi J.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 467 Issue: 4 Pages: 1097-102
- DOI
  10.1016/j.bbrc.2015.09.072
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-23240058, KAKENHI-PROJECT-25250011, KAKENHI-PROJECT-14J00467, KAKENHI-PROJECT-25290038
[Journal Article] Gene-content evolution in discobid mitochondria deduced from the phylogenetic position and complete mitochondrial genome of Tsukubamonas globosa.2014
- Author(s)
  Kamikawa R, Kolisko M, Nishimura Y, Yabuki A, rown MW, Sohta A. Ishikawa, Ishida K, Roger AJ, Hashimoto T, Inagaki Y
- Journal Title
  
  Genome Biology and Evolution
  
  Volume: 第6巻2号 Issue: 2 Pages: 306-315
- DOI
  10.1093/gbe/evu015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00007, KAKENHI-PROJECT-13J00789, KAKENHI-PLANNED-23117005, KAKENHI-PLANNED-23117006, KAKENHI-PROJECT-23247038, KAKENHI-PROJECT-23405013, KAKENHI-PROJECT-221S0002
[Journal Article] Draft genome sequence of Rhodococcus erythropolis JCM 6824, an aurachin RE antibiotic producer.2014
- Author(s)
  Kitagawa, W., Hata, M., Sekizuka, T., Kuroda, M., and Ishikawa, J.
- Journal Title
  
  Genome Announcement
  
  Volume: 2 Issue: 5
- DOI
  10.1128/genomea.01026-14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108010, KAKENHI-PLANNED-23117005, KAKENHI-PUBLICLY-25108728, KAKENHI-PROJECT-25650136
[Journal Article] RY-coding and non-homogeneous models ameliorate the maximum-likelihood inferences from nucleotide sequence data with parallel compositional heterogeneity.2012
- Author(s)
  Ishikawa SA, Inagaki Y, Hashimoto T.
- Journal Title
  
  Evolutionary Bioinformatics
  
  Volume: 8 Pages: 357-371
- DOI
  10.4137/ebo.s9017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370031, KAKENHI-PLANNED-23117006, KAKENHI-PROJECT-23247038, KAKENHI-ORGANIZER-23117001, KAKENHI-PLANNED-23117005
[Presentation] マウス卵細胞からの変異型ミトコンドリアDNA消失機構の解明を目指して2024
- Author(s)
  石川香
- Organizer
  第4回有性生殖研究会
- Invited
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] Drp1機能不全によるミトコンドリア病病態の多様化2023
- Author(s)
  石川香、堅田俊、本間耀、石原孝也、石原直忠、中田和人
- Organizer
  第21回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] 加齢に伴うミトコンドリアDNAの遺伝様式の変化2023
- Author(s)
  石川香、安原菜々子、伊藤香菜子、佐々木悠馬、林克彦、中田和人
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] マウス逆遺伝学的手法を用いた「老化ミトコンドリア（mtDNA）原因説」の検証2023
- Author(s)
  玉城大敬、石川香、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] Nuclear-mitochondrial sequenceの分類学への応用2023
- Author(s)
  井上聡、石川香、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] Generation and Pathogenic Analyses of Mice with a Mutation in the tRNALeu(UUR) Gene2023
- Author(s)
  Kaori Ishikawa, Haruna Tani, Fan-Yan Wei, and Kazuto Nakada
- Organizer
  The Cold Spring Harbor Asia conference on Mitochondria and Metabolism in Health and Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] モデルマウスを用いた「老化ミトコンドリア（mtDNA）原因説」の再検証2023
- Author(s)
  玉城大敬、石川香、中田和人
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] ミトコンドリア病MELASのモデルマウス作出に向けた基礎研究2023
- Author(s)
  永田留理、日比保乃郁、石川香、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] ミトコンドリア機能異常によって誘発された筋委縮における持久性運動の効果2023
- Author(s)
  花田翔、白井隆長、石川香、武政徹、中田和人
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] ミトコンドリアDNAの突然変異ががんの性質に与える影響2023
- Author(s)
  齊藤さくら、中田和人、石川香
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PLANNED-23H04951
[Presentation] Diversification of mitochondrial disease pathologies through nuclear-mitochondrial crosstalk2022
- Author(s)
  Kaori Ishikawa
- Organizer
  The 45th Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] ミトコンドリアの機能と糖尿病のかかわり2022
- Author(s)
  石川香
- Organizer
  全国臨床糖尿病医会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] ミトコンドリアの分裂を起点としたミトコンドリアの品質管理と病態抑制2021
- Author(s)
  石川香、堅田俊、石原孝也、小笠原絵美、川口敦史、石原直忠、中田和人
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] mtDNAに病原性突然変異を有するモデルマウス作出の試み2021
- Author(s)
  石川香、谷春菜、中田和人
- Organizer
  第20回日本ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] mtDNA改変モデルマウス作出の試み2021
- Author(s)
  石川香、谷春菜、中田和人
- Organizer
  第6回ゲノム編集学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] Fission-triggered mitochondrial quality control is essential to suppress expression of disease phenotypes due to pathogenic mtDNA mutation2021
- Author(s)
  Kaori Ishikawa, Shun Katada, Takaya Ishihara, Emi Ogasawara, Naotada Ishihara, Kazuto Nakada
- Organizer
  The Cold Spring Harbor Asia conference on Mitochondria and Metabolism in Health and Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00225
[Presentation] 突然変異型MFN2の時期特異的発現調節による神経変性の病態比較2020
- Author(s)
  石川香、山本智、服部聡子、西村尚也、松本寛和、宮川剛、中田和人
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] 突然変異型MFN2の神経特異的な誘導性発現による病態の評価2020
- Author(s)
  石川香
- Organizer
  2019年度文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] Generation and analysis of trans-mitochondrial mice carrying mtDNA with a point mutation in tRNALeu(UUR) gene.2019
- Author(s)
  2.Haruna Tani, Kaori Ishikawa, Jun-Ichi Hayashi, Kazuto Nakada
- Organizer
  The 16th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 19th Conference of Japan Society for Mitochondrial Research and Medicine [J-mit]
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons.2019
- Author(s)
  34.Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  The Cold Spring Harbor Asia conference on Mitochondria and Metabolism in Health and Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] Human neurodegenerative disease-like phenotypes induced by acquired expression of mutant MFN2 in mice.2019
- Author(s)
  1.Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Haruna Tani, Hirokazu Matsumoto, Tsuyoshi Miyakawa, and Kazuto Nakada
- Organizer
  The 16th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 19th Conference of Japan Society for Mitochondrial Research and Medicine [J-mit]
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] The D210V mutation of Mfn2 in neurons induces different pathologies in severity depends on its expression timing2018
- Author(s)
  Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  Keystone Symposia -Mitochondrial Biology (Z1)-
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] The importance of Mfn2 in neuronal function from juvenile to adult phase2018
- Author(s)
  Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  The 1st International Mitochondria Meeting for Young Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons2018
- Author(s)
  Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  The 41st Annual Meeting of the Molecular Biology Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons2018
- Author(s)
  Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  The 41st Annual Meeting of the Molecular Biology Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] The D210V mutation of Mfn2 in neurons induces different pathologies in severity depends on its expression timing2018
- Author(s)
  Kaori Ishikawa
- Organizer
  Keystone Symposia “Mitochondrial Biology”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] The importance of Mfn2 in neuronal function from juvenile to adult phase2018
- Author(s)
  Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  International YoungMito “The 1st International Mitochondria Meeting for Young Scientists”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] The importance of Mfn2 in neuronal function from juvenile to adult phase2018
- Author(s)
  Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
- Organizer
  International YoungMito “The 1st International Mitochondria Meeting for Young Scientists”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] マウス培養細胞は組織よりも高い割合のミトコンドリアDNA突然変異を許容できる2018
- Author(s)
  石川香、小林晃平、山田亮仁、梅原萌、岡敏彦、中田和人
- Organizer
  第18回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] マウス培養細胞は組織よりも高い割合のミトコンドリアDNA突然変異を許容できる2018
- Author(s)
  石川香、小林晃平、山田亮仁、梅原萌、岡敏彦、中田和人
- Organizer
  第18回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-18K06203
[Presentation] The D210V mutation of Mfn2 in neurons induces different pathologies in severity depends on its expression timing2018
- Author(s)
  Kaori Ishikawa
- Organizer
  Keystone Symposia “Mitochondrial Biology”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] 神経におけるMfn2のD210V突然変異は発現時期によって重症度の異なる病態を引き起こす2017
- Author(s)
  石川香、山本智、服部聡子、西村尚也、三藤崇行、松本寛和、宮川剛、中田和人
- Organizer
  第17回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] The importance of mitochondrial fission in preventing disease phenotypes induced by a pathogenic mtDNA mutation.2016
- Author(s)
  Ishikawa K, Katada S, Ogasawara E, Homma Y, Ishihara T, Mito T, Mihara K, Hayashi JI, Ishihara N, Nakada K.
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 16th Conference of Japanese Siciety of Mitochondrial Research and Medicine [J-mit].
- Place of Presentation
  TKPガーデンシティ品川, Shinagawa, Tokyo, Japan.
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] ミトコンドリア病の多様な病態発症機構の理解に向けたアプローチ～核-ミトコンドリア間クロストーク～．2016
- Author(s)
  石川香、堅田俊、小笠原絵美、本間耀、石原孝也、三藤崇行、三原勝芳、林純一、石原直忠、中田和人．
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市.
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K18535
[Presentation] ミトコンドリア・ダイナミクスの破綻が突然変異型mtDNAの組織内含有率に及ぼす影響2014
- Author(s)
  石川香、堅田俊、石原孝也、櫻澤遼太、小笠原絵美、林純一、三原勝芳、石原直忠、中田和人
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  福岡
- Year and Date
  2014-12-03
- Data Source
  KAKENHI-PLANNED-23117005

1. Nozaki Tomoyoshi (60198588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. HASHIMOTO Tetsuo (50208451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KURODA Makoto (80317411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKAO Keizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. INAGAKI Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 竹永啓三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 曽田学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 中田和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 石原孝也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 林純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 安川武宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 石川淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishikawa Kaori 石川 香

ISHIKAWA Kaori 石川 香

Research Projects

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Co-Researchers

Inheritance of mitochondrial genome for the next generationPrincipal Investigator

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Studies on mechanisms of age-dependent disappearance of mutant mitochondrial DNA from germ line cellsPrincipal Investigator

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Elucidation of mechanisms of neurodegeneration by reversible regulation of mitochondrial dynamicsPrincipal Investigator

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An approach from crosstalks of nuclei-mitochondria to disease mechanisms of mitochondrial diseasesPrincipal Investigator

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Multidirectional evolution of mitochondria

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[Journal Article] Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment2024

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[Journal Article] Pearson syndrome-like anemia induced by accumulation of mutant mtDNA and anemia with imbalanced white blood cell lineages induced by Drp1 deletion in a murine model2022

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[Journal Article] Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation2022

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[Journal Article] Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease2021

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[Journal Article] A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome2021

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[Journal Article] Neuronal degeneration and cognitive impairment can be prevented via the normalization of mitochondrial dynamics2021

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[Journal Article] Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells2021

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[Journal Article] Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK‐448, for its anti‐tumor efficacy in a rat xenograft model2020

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[Journal Article] Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells.2019

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NAID

Ishikawa Kaori 石川香

ISHIKAWA Kaori 石川香