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ONO Yusuke  小野 裕介

ORCIDConnect your ORCID iD *help
Researcher Number 40742648
Other IDs
Affiliation (Current) 2019: 医療法人徳洲会札幌東徳洲会病院医学研究所, 臨床生体情報解析部, 部門長
Affiliation (based on the past Project Information) *help 2017: 医療法人徳洲会札幌東徳洲会病院医学研究所, 臨床生体情報解析部, 部門長
2016: 医療法人徳洲会札幌東徳洲会病院付属臨床研究センター, 臨床生体情報解析部, 部門長
2015: 医療法人徳洲会札幌東徳洲会病院付属臨床研究センター, その他部局等, 研究員
2015: 医療法人徳洲会札幌東徳洲会病院付属臨床研究センター, 臨床生体情報解析部, 研究員
Review Section/Research Field
Principal Investigator
Applied biochemistry
Except Principal Investigator
Gastroenterology / Respiratory organ internal medicine
Keywords
Principal Investigator
膵腸相関 / 膵がん / 自然免疫 / 腸内細菌叢 / 医食同源 / 膵癌 / 腸内細菌 / 悪性化 / 腸内環境
Except Principal Investigator
膵癌 … More / 液体生検 / デジタルPCR / 肺癌 / EGFR T790M / EGFR C797S / ALK G1202R / EGFR / ALK / KRAS / T790M / 体細胞変異解析 / 次世代シーケンサー / コピー数多型 / メチル化解析 / 癌 / 遺伝子 / 細胞・組織 / 臨床 / IPMN / GNAS / 細胞 Less
  • Research Projects

    (4 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (9 People)
  •  若年発症膵癌の分子構造Ongoing

    • Principal Investigator
      笹島 順平
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Asahikawa Medical College
  •  ヒト生細胞リソースによる膵癌悪性化機構の多様性解明Ongoing

    • Principal Investigator
      水上 裕輔
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Asahikawa Medical College
  •  Monitoring of Emerging Resistance of Lung Cancer using Liquid Biopsy

    • Principal Investigator
      TANNO Sachie
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Asahikawa Medical College
  •  Pancreatic-Intestinal Crosstalk: a novel approach to elucidate the tumorigenic process of PDACPrincipal Investigator

    • Principal Investigator
      ONO Yusuke
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied biochemistry
    • Research Institution
      Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital

All 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving ‘subsampling’ issues2017

    • Author(s)
      Ono Yusuke、Sugitani Ayumu、Karasaki Hidenori、Ogata Munehiko、Nozaki Reo、Sasajima Junpei、Yokochi Tomoki、Asahara Shingo、Koizumi Kazuya、Ando Kiyohiro、Hironaka Katsunori、Daito Tsutomu、Mizukami Yusuke
    • Journal Title

      Molecular Oncology

      Volume: 11 Pages: 1448-1458

    • DOI
      10.1002/1878-0261.12110
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-15K14716
  • [Journal Article] Tracking the clonal evolution of adenosquamous carcinoma, a rare variant of intraductal papillary mucinous neoplasm of the pancreas.2016

    • Author(s)
      Matsuzaka S, Karasaki H, Ono Y, Ogata M, Oikawa K, Tamakawa S, Chiba S, Muraki M, Yokochi T, Funakoshi H, Kono T, Nagashima K, Mizukami Y.
    • Journal Title

      Pancreas

      Volume: XX

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Journal Article] The protein expression level of Gli2 is a feasible marker of ligand-dependent hedgehog activation in pancreatic neoplasms.2016

    • Author(s)
      Sugiyama Y, Sasajima J, Mizukami Y, Koizumi K, Kawamoto T, Karasaki H, Yusuke Ono, Tanabe H, Fujiya M, Kohgo Y.
    • Journal Title

      Pol J Pathol

      Volume: XX

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Presentation] Plasma DNA genotyping using digital PCR for surveillance of pancreatic cancer in high-risk individuals2017

    • Author(s)
      Mizukami Y、Ono Y、Karasaki H、Koizumi K、Okada T、Sasajima J、Yamada M、Asahara S、Kawakubo K、Maguchi H
    • Organizer
      25th UEG Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09472
  • [Presentation] An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving “subsampling” issues.2017

    • Author(s)
      Ono Y,Sugitani A,Karasaki H,Ogata M,Nozaki R,Sasajima J, Mizukami Y
    • Organizer
      25th UEG Week
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Presentation] Concomitant pancreatic cancers arising adjacent to index IPMN share identical KRAS mutations and are associated with a favorable prognosis2017

    • Author(s)
      Omori Y、Ono Y、Tanino M、Karasaki H、Shinohara T、Tanaka S、Maguchi H、Mizukami Y
    • Organizer
      25th UEG Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09472
  • [Presentation] 血漿由来遊離核酸より微量変異を検出する感度の向上を目的としたデジタルPCR法の応用2017

    • Author(s)
      小野裕介
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-15K09239
  • [Presentation] Improved digital PCR protocol to capture low-copy KRAS mutations in plasma cell-free DNA by pre-amplification 血漿由来遊離核酸より微量変異を検出する感度の向上を目的としたデジタルPCR法の応用2017

    • Author(s)
      Ono Y、Karasaki H、Sasajima J、Mizukami Y
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K09472
  • [Presentation] digital PCR protocol to capture low-copy KRAS mutations in plasma cell-free DNA by pre-amplification2017

    • Author(s)
      Ono Y, Karasaki H,Sasajima J,Mizukami Y.
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Presentation] An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving ”subsampling”issues2017

    • Author(s)
      Ono Y、Sugitani A、Karasaki H、Ogata M、Nozaki R、Sasajima J、Mizukami Y
    • Organizer
      25th UEG Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09472
  • [Presentation] Plasma DNA genotyping using digital PCR for surveillance of pancreatic cancer in high-risk individuals2017

    • Author(s)
      Mizukami Y,Ono Y,Karasaki H, Koizumi K, Okada T, Sasajima J, Yamada M, Asahara S, Kawakubo K, Maguchi H
    • Organizer
      25th UEG Week
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Presentation] Digital PCR-based liquid biopsy for early detection of pancreatic cancer.2017

    • Author(s)
      Mizukami Y,Ono Y,Karasaki H,Okada T,Sasajima J.
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Presentation] Digital PCR-based liquid biopsy for early detection of pancreatic cancer2017

    • Author(s)
      Mizukami Y、Ono Y、Karasaki H、Okada T、Sasajima J
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K09472
  • [Presentation] 血漿遊離核酸を用いた膵腫瘍悪性度診断2017

    • Author(s)
      岡田哲弘、水上裕輔、笹島順平、小野裕介、唐崎秀則、他
    • Organizer
      第25回日本消化器病関連学会週間
    • Data Source
      KAKENHI-PROJECT-17K09472
  • [Presentation] 非小細胞肺癌を対象としたデジタルPCRによるliquid biopsy2016

    • Author(s)
      小野 裕介, 佐々木 高明, 吉田 遼平, 安藤 清宏, 大崎 能伸, 水上 裕輔
    • Organizer
      日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K09239
  • [Presentation] 液体生検による肺がん診断の臨床応用2016

    • Author(s)
      佐々木高明、水上裕輔、小野祐介、丹野幸恵ら
    • Organizer
      日本臨床腫瘍学会
    • Place of Presentation
      神戸
    • Year and Date
      2016-07-30
    • Data Source
      KAKENHI-PROJECT-15K09239
  • [Presentation] Plasma DNA genotyping using digital PCR for early detection of pancreatic cancer2015

    • Author(s)
      Mizukami Y, Ono Y, Karasaki H, Asahara S, Ando K, Shinohara T, Nagashima K
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K14716
  • [Presentation] Plasma DNA genotyping using digital PCR for early detection of pancreatic neoplasm2015

    • Author(s)
      Mizukami Y, Ono Y, Karasaki H, Ogata M, Koizumi K, Ando K, Yokochi T, Yamada M, Kono T, Nagashima K
    • Organizer
      6th Annual Meeting of the American Pancreatic Association
    • Place of Presentation
      San Diego
    • Year and Date
      2015-11-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14716
  • 1.  水上 裕輔 (30400089)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 2.  笹島 順平 (80451467)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 3.  TANNO Sachie (80455724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  YOSHIDA Ryouhei (40792883)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  佐々木 高明 (70516997)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  前本 篤男 (40400113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  中村 公則 (80381276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  田中 宏樹 (70596155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  唐崎 秀則 (50374806)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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