JIN MEIHUA 金美花

Researcher Number	40746773
Affiliation (based on the past Project Information) *help	2016 – 2017: 国立研究開発法人国立循環器病研究センター, 研究所, 研究員 2016: 国立循環器病研究センター, 肺高血圧症先端医学研究部, 研究員 2015: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員
Review Section/Research Field	Principal Investigator General physiology Except Principal Investigator Cardiovascular medicine / General physiology
Keywords	Principal Investigator CHP3 / ベータ遮断薬 / Ca2+シグナル / ＮＨＥ１ / 心不全 / CHP3欠損マウス / 低酸素負荷 / Ca2+結合蛋白質 / 心肥大 / 肺高血圧 … More / Ca2+-binding protein / hypoxia / hypertrophy / heart failure … More Except Principal Investigator 放射光Ｘ線回折法 / 心筋拡張機能障害 / 放射光X線回折法 / 心筋収縮タンパク質 / 心臓拡張機能障害 / 糖尿病 / 循環器・高血圧 / ベータリセプター / Na+/H+交換輸送体 / カテコールアミン / 心不全 / 遺伝子改変マウス / シグナル伝達 / イオン輸送体 / ノックアウトマウス / 低酸素刺激 / 心肥大 / Ca2+結合蛋白質 / 細胞内シグナル伝達 / 心筋リモデリング Less

Synchrotron radiation investigation of cardiac contractile protein dynamics at end diastole in a type 2 prediabetes model rat
- Principal Investigator
  
  SHIRAI Mikiyasu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
Study on the drug exercise therapy that is effective for cardiac hypertrophy heart failure that develops in Ca2 + load model mousePrincipal Investigator
- Principal Investigator
  
  JIN MEIHUA
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Amplification of intracellular signaling initiated near the plasma membrane transporters
- Principal Investigator
  
  Wakabayashi Shigeo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Osaka Medical College
  National Cardiovascular Center Research Institute

All 2017 2016 2015

All Journal Article Presentation

[Journal Article] Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model.2017
- Author(s)
  Pearson JT, Yoshimoto M, Chen YC, Sultani R, Edgley AJ, Nakaoka H, Nishida M, Umetani K, Waddingham MT, Jin HL, Zhang Y, Kelly DJ, Schwenke DO, Inagaki T, Tsuchimochi H, Komuro I, Yamashita S, Shirai M.
- Journal Title
  
  Sci Rep
  
  Volume: Dec 22;7(1) Issue: 1 Pages: 18108-18108
- DOI
  10.1038/s41598-017-18485-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16033, KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PROJECT-16H05126, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-16K15452
[Journal Article] Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.2016
- Author(s)
  Jin H，Fujita T，Jin M，Kurotani R，Hidaka Y，Cai W，Suita K，Prajapati R，Liang C，Ohnuki Y，Mototani Y，Umemura M，Yokoyama U，Sato M，Okumura S，Ishikawa Y.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 印刷中 Issue: 1 Pages: 77-87
- DOI
  10.1007/s12576-016-0509-5
- NAID
  40021443658
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-15K18975, KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K09208, KAKENHI-PROJECT-18K08138, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-15H05761
[Journal Article] Heterozygous deletion of sarcolipin maintains normal cardiac function.2015
- Author(s)
  Shimura D, Kusakari Y, Sasano T, Nakashima Y, Nakai G, Jiao Q, Jin M, Yokota T, Ishikawa Y, Nakano A, Goda N, Minamisawa S.
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 310(1) Issue: 1 Pages: 92-103
- DOI
  10.1152/ajpheart.00411.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08190, KAKENHI-PROJECT-15K18975, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26893124, KAKENHI-PROJECT-25461045, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-16K15184
[Journal Article] Effect of inflammatory factor-induced cyclo-oxygenase expression on the development of reperfusion-related no-reflow phenomenon in acute myocardial infarction2015
- Author(s)
  Qibin Jiao, Qiang Ke, Weiwei Li, MeiHua Jin, YanLuo, Linan Zhang, DongYang and Xingwei Zhang
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 42 Issue: 2 Pages: 162-170
- DOI
  10.1111/1440-1681.12339
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18975
[Presentation] 低酸素により誘発される心肥大におけるカルシニュリンB用蛋白質3（CHP3)の新しい役割2017
- Author(s)
  金美花、若林繁夫、古林創史、土持裕胤、白井幹康、ピアソン　ジェームズ、大郷剛
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Data Source
  KAKENHI-PROJECT-16K15452
[Presentation] A Novel Role of Calcineurin B Homologous Protein 3 in Hypoxia-induced Cardiac Hypertrophy and Heart Failure2017
- Author(s)
  MeiHua Jin, Shigeo Wakabayashi, Soushi Kobayashi, Hirotsugu Tsuchimochi, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo.
- Organizer
  The 94th Annual Meeting of the Phisiological Society
- Place of Presentation
  Hamamatu
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K18975
[Presentation] カルシニュリンB様蛋白質3（CHP3）ノックアウトマウスを用いた慢性低酸素負荷による心肥大2017
- Author(s)
  金　美花、若林　繁夫、古林創史、土持　裕胤、白井　幹康、ピアソン　ジェームズ、
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松アクトシティコングレスセンター
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Production of calcineurin B homologous protein 3 knockout mice and analysis of cardiac function2016
- Author(s)
  Shigeo Wakabayashi,MeiHua Jin, Soushi Kobayashi, Hirotsugu Tsuchimochi, Mikiyasu Shirai
- Organizer
  The 93th Annual Meeting of the Phisiological Society
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K18975
[Presentation] カルシニュリンB様蛋白質3（CHP3）ノックアウトマウスの作成と心機能解析2016
- Author(s)
  金美花、若林繁夫、古林創史、土持裕胤、白井幹康
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] マウス大動脈狭窄心不全モデルにおける果実に含有するポリフェノール類の病態改善効果の検討2016
- Author(s)
  若林繁夫、スクマラン・ビジェヤクマ、金美花、稲垣薫克、土持裕胤、白井幹康
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460312
[Presentation] Effects of Epac-specific inhibitor, ESI-09 on heart failure model mice2015
- Author(s)
  Jin , M., Wakabayashi, S., Tsuchimochi, H., Shirai, M.
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-26460312

1. Wakabayashi Shigeo (70158583)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. Shirai Mikiyasu (70162758)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. TO Seikon (90590646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SEN Toun (30616941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. INAGAKI Tadakatsu (20638366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 土持裕胤 (60379948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Pearson James (30261390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. YAGI Naoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 南沢享

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 草刈洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 奥村敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 石川義弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 梅村将就

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

JIN MEIHUA 金 美花

Research Projects

Research Products

Co-Researchers

Synchrotron radiation investigation of cardiac contractile protein dynamics at end diastole in a type 2 prediabetes model rat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the drug exercise therapy that is effective for cardiac hypertrophy heart failure that develops in Ca2 + load model mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Amplification of intracellular signaling initiated near the plasma membrane transporters

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Heterozygous deletion of sarcolipin maintains normal cardiac function.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of inflammatory factor-induced cyclo-oxygenase expression on the development of reperfusion-related no-reflow phenomenon in acute myocardial infarction2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 低酸素により誘発される心肥大におけるカルシニュリンB用蛋白質3（CHP3)の新しい役割2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] A Novel Role of Calcineurin B Homologous Protein 3 in Hypoxia-induced Cardiac Hypertrophy and Heart Failure2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] カルシニュリンB様蛋白質3（CHP3）ノックアウトマウスを用いた慢性低酸素負荷による心肥大2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Production of calcineurin B homologous protein 3 knockout mice and analysis of cardiac function2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] カルシニュリンB様蛋白質3（CHP3）ノックアウトマウスの作成と心機能解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウス大動脈狭窄心不全モデルにおける果実に含有するポリフェノール類の病態改善効果の検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Effects of Epac-specific inhibitor, ESI-09 on heart failure model mice2015

Author(s)

JIN MEIHUA 金美花