Shichino Yuichi 七野悠一

Researcher Number	40748365
Other IDs	https://orcid.org/0000-0002-0093-1185
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 開拓研究所, 上級研究員 2025: 基礎生物学研究所, 細胞応答研究室, 研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人理化学研究所, 開拓研究所, 上級研究員 2022 – 2024: 国立研究開発法人理化学研究所, 開拓研究本部, 研究員 2021 – 2022: 国立研究開発法人理化学研究所, 開拓研究本部, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 43010:Molecular biology-related Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator 翻訳 / 次世代シーケンサー / RNA / 近傍標識 / リボソームプロファイリング / 複合体形成 / 局所翻訳 / リソソーム / 反応場 / 顆粒精製 … More / RNP顆粒 / eIF4A1 / グルタミン / 翻訳開始 / 代謝 … More Except Principal Investigator タンパク質 / mRNA / 蛋白質 / 反応場 / 翻訳 Less

翻訳と反応場から考える蛋白質の新しい社会像の領域推進
- Principal Investigator
  
  小林穂高
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokushima
リソソームを「反応場」とする翻訳・複合体形成・局在化の協奏Principal Investigator
- Principal Investigator
  
  七野悠一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
非典型局所翻訳を包括的に解明するAPEX-Ribo-Seq法の確立Principal Investigator
- Principal Investigator
  
  七野悠一
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
細胞内顆粒P-bodyによるmRNAの空間的制御を介した細胞周期調節機構Principal Investigator
- Principal Investigator
  
  七野悠一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Institute of Physical and Chemical Research
APEX-Ribo-Seq: 近傍標識による非典型局所翻訳の網羅解析Principal Investigator
- Principal Investigator
  
  七野悠一
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Physical and Chemical Research
Cooperative expression regulation by eukaryotic translation initiation factor eIF4A1 and glutamine metabolismPrincipal Investigator
- Principal Investigator
  
  Shichino Yuichi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Institute of Physical and Chemical Research

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] A parasitic fungus employs mutated eIF4A to survive on rocaglate-synthesizing Aglaia plants2023
- Author(s)
  Chen Mingming、Kumakura Naoyoshi、Saito Hironori、Muller Ryan、Nishimoto Madoka、Mito Mari、Gan Pamela、Ingolia Nicholas T、Shirasu Ken、Ito Takuhiro、Shichino Yuichi、Iwasaki Shintaro
- Journal Title
  
  eLife
  
  Volume: 12
- DOI
  10.7554/elife.81302
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0397, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-22H00364
[Journal Article] Thor-Ribo-Seq: ribosome profiling tailored for low input with RNA-dependent RNA amplification2023
- Author(s)
  Mito Mari、Shichino Yuichi、Iwasaki Shintaro
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.01.15.524129
- Open Access
- Data Source
  KAKENHI-PROJECT-21K15023
[Journal Article] ILF3 prion-like domain regulates gene expression and fear memory under chronic stress2023
- Author(s)
  Yamashita Akira、Shichino Yuichi、Fujii Kazuki、Koshidaka Yumie、Adachi Mayumi、Sasagawa Eri、Mito Mari、Nakagawa Shinichi、Iwasaki Shintaro、Takao Keizo、Shiina Nobuyuki
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 3 Pages: 106229-106229
- DOI
  10.1016/j.isci.2023.106229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19281, KAKENHI-PROJECT-21K15006, KAKENHI-PROJECT-18H05213, KAKENHI-PLANNED-21H05274, KAKENHI-PUBLICLY-22H05614, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-23K23816
[Journal Article] Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion?FAK axis2023
- Author(s)
  Wakigawa Taisei、Kimura Yusuke、Mito Mari、Tsubaki Toshiya、Saito Hironori、Khan Abdul Haseeb、Yamamori Tohru、Yamazaki Tomokazu、Higashibata Akira、Tsuboi Tatsuhisa、Saito Taku、Higashitani Atsushi、Shichino Yuichi、Iwasaki Shintaro
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.01.18.524628
- Open Access
- Data Source
  KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-23KJ0444
[Journal Article] Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm2023
- Author(s)
  Miyake Takahito、Inoue Yuichi、Shao Xinyan、Seta Takehito、Aoki Yuto、Nguyen Pham Khanh Tien、Shichino Yuichi、Sasaki Junko、Sasaki Takehiko、Ikawa Masahito、Yamaguchi Yoshiaki、Okamura Hitoshi、Iwasaki Shintaro、Doi Masao
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 3 Pages: 112157-112157
- DOI
  10.1016/j.celrep.2023.112157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06594, KAKENHI-PROJECT-22K18384, KAKENHI-PROJECT-22K15274, KAKENHI-ORGANIZER-20H05782, KAKENHI-PLANNED-20H05783, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04987, KAKENHI-PROJECT-21H02680, KAKENHI-PROJECT-20K21426, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-18H04015, KAKENHI-PROJECT-23K27319
[Journal Article] Multifarious translational regulation during replicative aging in yeast.2022
- Author(s)
  Zhao T, Chida A, Shichino Y, Choi D, Mizunuma M, Iwasaki S, and Ohya Y
- Journal Title
  
  J Fungi (Basal)
  
  Volume: 8(9) Issue: 9 Pages: 938-938
- DOI
  10.3390/jof8090938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-23K23483, KAKENHI-PROJECT-23K23527
[Journal Article] Compounds for selective translational inhibition.2022
- Author(s)
  Shichino Y and Iwasaki S
- Journal Title
  
  Curr Opin Chem Biol.
  
  Volume: 69 Pages: 102158-102158
- DOI
  10.1016/j.cbpa.2022.102158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21K15023
[Journal Article] Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells2022
- Author(s)
  Wu Quan、Shichino Yuichi、Abe Takaya、Suetsugu Taeko、Omori Ayaka、Kiyonari Hiroshi、Iwasaki Shintaro、Matsuzaki Fumio
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 470-470
- DOI
  10.1038/s41467-022-28097-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-18H04003, KAKENHI-PROJECT-19K22406
[Journal Article] eIF2B-capturing viral protein NSs suppresses the integrated stress response2021
- Author(s)
  Kashiwagi Kazuhiro、Shichino Yuichi、Osaki Tatsuya、Sakamoto Ayako、Nishimoto Madoka、Takahashi Mari、Mito Mari、Weber Friedemann、Ikeuchi Yoshiho、Iwasaki Shintaro、Ito Takuhiro
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 7102-7102
- DOI
  10.1038/s41467-021-27337-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20178, KAKENHI-PROJECT-19H03172, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-21H05281, KAKENHI-PROJECT-19K22406
[Journal Article] Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons2021
- Author(s)
  Ichihara Kazuya、Matsumoto Akinobu、Nishida Hiroshi、Kito Yuki、Shimizu Hideyuki、Shichino Yuichi、Iwasaki Shintaro、Imami Koshi、Ishihama Yasushi、Nakayama Keiichi I
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 13 Pages: 7298-7317
- DOI
  10.1093/nar/gkab549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04844, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-21H02404, KAKENHI-PROJECT-20J20906, KAKENHI-PROJECT-21J15131, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-21K17856, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22406
[Presentation] eIF4A1 facilitates LARP1-mediated translation repression during mTORC1 inhibition2022
- Author(s)
  Yuichi Shichino, Mari Mito, Kazuhiro Kashiwagi, Mari Takahashi, Takuhiro Ito, Nicholas T. Ingolia, Shintaro Iwasaki
- Organizer
  RNAフロンティアミーティング2021
- Data Source
  KAKENHI-PROJECT-21K15023
[Presentation] eIF4A1 facilitates LARP1-mediated translation repression during mTORC1 inhibition2022
- Author(s)
  Yuichi Shichino,Mari Mito,Kazuhiro Kashiwagi,Mari Takahashi,Takuhiro Ito,Nicholas T. Ingolia,Shintaro Iwasaki
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21K15023
[Presentation] 翻訳開始因子eIF4A1はLARP1による翻訳抑制を促進する2022
- Author(s)
  七野悠一,水戸麻理,柏木一宏,高橋真理,伊藤拓宏,Nicholas T. Ingolia,岩崎信太郎
- Organizer
  日本プロテオーム学会2022年大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15023
[Presentation] Novel repressive role of eIF4A1 during mTORC1 inhibition2022
- Author(s)
  Yuichi Shichino
- Organizer
  第60回生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15023
[Presentation] 翻訳開始因子eIF4A1とグルタミン代謝による協調的な発現制御機構2021
- Author(s)
  七野悠一、岩崎信太郎
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15023
[Presentation] A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition2021
- Author(s)
  Yuichi Shichino, Mari Mito, Nicholas T. Ingolia, Shintaro Iwasaki
- Organizer
  RNA 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15023
[Presentation] A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition2021
- Author(s)
  Yuichi Shichino, Mari Mito, Nicholas T. Ingolia, Shintaro Iwasaki
- Organizer
  EMBL Conference: Protein Synthesis and Translational Control
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15023

1. 小林穂高 (80802975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 柏木一宏 (60732980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松尾芳隆 (00725252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMAGUCHI Yoshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 熊倉直祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 椎名伸之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shichino Yuichi 七野 悠一

Research Projects

Research Products

Co-Researchers

翻訳と反応場から考える蛋白質の新しい社会像の領域推進

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リソソームを「反応場」とする翻訳・複合体形成・局在化の協奏Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非典型局所翻訳を包括的に解明するAPEX-Ribo-Seq法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞内顆粒P-bodyによるmRNAの空間的制御を介した細胞周期調節機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

APEX-Ribo-Seq: 近傍標識による非典型局所翻訳の網羅解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cooperative expression regulation by eukaryotic translation initiation factor eIF4A1 and glutamine metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A parasitic fungus employs mutated eIF4A to survive on rocaglate-synthesizing Aglaia plants2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thor-Ribo-Seq: ribosome profiling tailored for low input with RNA-dependent RNA amplification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ILF3 prion-like domain regulates gene expression and fear memory under chronic stress2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion?FAK axis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multifarious translational regulation during replicative aging in yeast.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Compounds for selective translational inhibition.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells2022

Author(s)

Journal Title

DOI

Data Source

Shichino Yuichi 七野悠一