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Higuchi Yumiko  樋口 由美子

ORCIDConnect your ORCID iD *help
Researcher Number 40757241
Other IDs
Affiliation (Current) 2025: 信州大学, 医学部, 講師(特定雇用)
Affiliation (based on the past Project Information) *help 2021 – 2023: 信州大学, 医学部, 講師(特定雇用)
2020 – 2022: 信州大学, 学術研究院保健学系, 講師(特定雇用)
Review Section/Research Field
Principal Investigator
Basic Section 52010:General internal medicine-related
Except Principal Investigator
Basic Section 52010:General internal medicine-related
Keywords
Principal Investigator
炎症 / シトルリン化フィブリノゲン / 好中球 / PAD4 / がん / 感染症 / PAD / NETs / 好中球細胞外トラップ
Except Principal Investigator
NETs … More / 形質転換能 / 遊走能 / 皮膚線維芽細胞 / 血管内皮細胞 / フィブリン / THP-1 / M1-マクロファージ / NETs形成能 / 好中球 / NETs形成能 / 内皮間葉転換能 / 細胞遊走能 / アミロイドβ1-42 / M1-Mφ分化 / 管状構造形成能 / 異常フィブリノゲン / フィブリノゲン Less
  • Research Projects

    (3 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (3 People)
  •  シトルリン化フィブリノゲンの好中球エフェクター機能に及ぼす影響Principal Investigator

    • Principal Investigator
      樋口 由美子
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Shinshu University
  •  Evaluation for extra-cellular function of dysfunctional fibrinogen and identification of its important residues

    • Principal Investigator
      Okumura Nobuo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Shinshu University
  •  Detection of neutrophil extracellular traps by measuring citrullinated fibrinogen in serumPrincipal Investigator

    • Principal Investigator
      Higuchi Yumiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Shinshu University

All 2022 2021 2020

All Journal Article Presentation

  • [Journal Article] Changes in serum citrullinated fibrinogen concentration associated with the phase of bacteremia patients.2021

    • Author(s)
      Fujimura S, Higuchi Y, Usami Y, Yamaura M, Higuchi T, Terasawa F, Okumura N.
    • Journal Title

      Clin Chim Acta .

      Volume: 512 Pages: 127-134

    • DOI

      10.1016/j.cca.2020.10.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07822, KAKENHI-PROJECT-20K07799
  • [Journal Article] Novel variant fibrinogen γ p.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment2021

    • Author(s)
      Yoda M, Kaido T, Kamijo T, Taira C, Higuchi Y, Arai S, Okumura N.
    • Journal Title

      Int J Hematology

      Volume: 114 Issue: 3 Pages: 325-333

    • DOI

      10.1007/s12185-021-03174-y

    • NAID

      120007180888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07799, KAKENHI-PROJECT-21K15945
  • [Journal Article] 28年間で解析した長野県内のフィブリノゲン異常症18家系28例2021

    • Author(s)
      上條途夢,海藤貴大, 依田将宏, 平千明, 樋口由美子,新井慎平, 竹澤由夏,奥村伸生.
    • Journal Title

      長臨技会誌

      Volume: 10 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Journal Article] Congenital fibrinogen disorder with a compound heterozygote possessing two novel FGB mutations, one qualitative and the other quantitative2020

    • Author(s)
      Yoda M, Kaido T, Taira C, Higuchi Y, Arai S, Okumura N.
    • Journal Title

      Thromb Res

      Volume: 196 Pages: 152-158

    • DOI

      10.1016/j.thromres.2020.08.031

    • NAID

      120007180892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Journal Article] A novel amino acid substitution, fibrinogen Bβp.Pro234Leu, associated with hypofibrinogenemia causing impairment of fibrinogen assembly and secretion2020

    • Author(s)
      Kaido T, Yoda M, Kamijo T, Arai S, Taira C, Higuchi Y, Okumura N.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 21 Issue: 24 Pages: 9422-9422

    • DOI

      10.3390/ijms21249422

    • NAID

      120007180887

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Presentation] Validation of a sandwich enzyme-linked immunosorbent assay to determine serum citrullinated fibrinogen concentration2022

    • Author(s)
      Tomoki Ichikawa, Tsubasa Sue, Satoshi Fujimura, Yoko Usami, Tsukasa Higuchi, Nobuo Okumura, Yumiko Higuchi
    • Organizer
      The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine (ASCPaLM)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07822
  • [Presentation] 好中球細胞外トラップ検出のためのMyeloperoxidase-DNA複合体測定法の基礎的検討2022

    • Author(s)
      市川 友喜、須江 翼、藤村 哲士、宇佐美 陽子、樋口 由美子
    • Organizer
      第40回日本臨床化学甲信越支部総会
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Presentation] Citrullinated fibrinogen for detection of neutrophil extracellular traps2022

    • Author(s)
      Tsubasa Sue, Tomoki Ichikawa, Satoshi Fujimura, Tsukasa Higuchi, Nobuo Okumura, Yumiko Higuchi
    • Organizer
      The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Presentation] がん細胞株におけるフィブリノゲンのシトルリン化とPAD発現2022

    • Author(s)
      服部 周生, 須江 翼, 市川 友喜, 大谷 ひかる, 藤村 哲士, 樋口 由美子
    • Organizer
      第 46 回長野県臨床検査学会
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Presentation] 新型コロナウイルス感染症における血中シトルリン化フィブリノゲン濃度の検討2022

    • Author(s)
      大谷ひかる、市川友喜 、藤村哲士、須江翼、服部周生、樋口由美子
    • Organizer
      第 46 回長野県臨床検査学会
    • Data Source
      KAKENHI-PROJECT-20K07822
  • [Presentation] 好中球細胞外トラップ検出のためのMyeloperoxidase-DNA複合体測定法の基礎的検討2022

    • Author(s)
      市川 友喜、須江 翼、藤村 哲士、宇佐美 陽子、樋口 由美子
    • Organizer
      第40回日本臨床化学甲信越支部総会
    • Data Source
      KAKENHI-PROJECT-20K07822
  • [Presentation] Validation of a sandwich enzyme-linked immunosorbent assay to determine serum citrullinated fibrinogen concentration2022

    • Author(s)
      omoki Ichikawa, Tsubasa Sue, Satoshi Fujimura, Yoko Usami, Tsukasa Higuchi, Nobuo Okumura, Yumiko Higuchi
    • Organizer
      The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Presentation] Citrullinated fibrinogen for detection of neutrophil extracellular traps2022

    • Author(s)
      Tsubasa Sue, Tomoki Ichikawa, Satoshi Fujimura, Tsukasa Higuchi, Nobuo Okumura, Yumiko Higuchi
    • Organizer
      The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine (ASCPaLM)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07822
  • [Presentation] 新型コロナウイルス感染症における血中シトルリン化フィブリノゲン濃度の検討2022

    • Author(s)
      大谷ひかる、市川友喜 、藤村哲士、須江翼、服部周生、樋口由美子
    • Organizer
      第 46 回長野県臨床検査学会
    • Data Source
      KAKENHI-PROJECT-20K07799
  • [Presentation] がん細胞株におけるフィブリノゲンのシトルリン化とPAD発現2022

    • Author(s)
      服部 周生, 須江 翼, 市川 友喜, 大谷 ひかる, 藤村 哲士, 樋口 由美子
    • Organizer
      第 46 回長野県臨床検査学会
    • Data Source
      KAKENHI-PROJECT-20K07822
  • [Presentation] 急性大動脈解離におけるシトルリン化フィブリノゲンの動態2021

    • Author(s)
      藤村哲士、樋口由美子、伊澤淳、宇佐美陽子、山浦洵、奥村伸生
    • Organizer
      第67回 日本臨床検査医学会 学術集会
    • Data Source
      KAKENHI-PROJECT-20K07822
  • [Presentation] 菌血症患者における血清中シトルリン化フィブリノゲンと炎症マーカーの関連2021

    • Author(s)
      藤村哲士,樋口由美子,宇佐美陽子,山浦 洵,樋口 司,寺澤文子,奥村伸生
    • Organizer
      第68回日本臨床検査医学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07799
  • 1.  Okumura Nobuo (60252110)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 2.  平 千明 (40779310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  新井 慎平 (70866053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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