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Noritake Kanako  則竹 香菜子

ORCIDConnect your ORCID iD *help
Researcher Number 40758067
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院医学系研究科(医学部), 学術専門職員
Affiliation (based on the past Project Information) *help 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 特任助教
2020 – 2022: 東京大学, 大学院医学系研究科(医学部), 特任研究員
2016 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 特任助教
2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 特任助教
Review Section/Research Field
Principal Investigator
Legal medicine / Basic Section 58040:Forensics medicine-related
Except Principal Investigator
Basic Section 58040:Forensics medicine-related / Legal medicine
Keywords
Principal Investigator
エタノール / 心筋細胞 / 心筋障害 / Hippo-YAP経路 / 毒性機序 / Δ9-テトラヒドロカンナビノール / 小胞体ストレス / AMPK / マクロピノサイトーシス / ERストレス … More / Δ9-THC / microRNA / YAP / 心筋細胞障害 / アルコール / 細胞間接着分子 / 細胞間接着 / 心筋細胞傷害 … More
Except Principal Investigator
法医学 / 代謝物 / 解糖系 / 細胞死 / 代謝産物 / 免疫細胞 / 炎症 / グルコース / 炎症性細胞死 / アセトアミノフェン / ガスダーミン / ヒ素 / 代謝 / マクロファージ / パイロトーシス / 法医病理 / プロテオーム / ヘム / タンパク質凝集体 / ミトコンドリア / プロテオミクス / メタボロミクス / 硫化水素 / p62 / フィブロネクチン / CORM-3 / 一酸化炭素 Less
  • Research Projects

    (5 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (3 People)
  •  Regulation mechanism of pyroptosis by metabolites

    • Principal Investigator
      Aki Toshihiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Tokyo Medical and Dental University
  •  The molecular mechanism of direct cardiotoxicity of cannabinoid, and the effect of ethanolPrincipal Investigator

    • Principal Investigator
      Noritake Kanako
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      The University of Tokyo
      Tokyo Medical and Dental University
  •  Involvement of YAP inactivation and microRNA in ethanol-induced cardiotoxicityPrincipal Investigator

    • Principal Investigator
      Noritake Kanako
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of carbon monoxide toxicity using water-soluble CORMs

    • Principal Investigator
      Aki Toshihiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  The role of Hippo-YAP pathway in alcohol-induced cardiac dysfunctionPrincipal Investigator

    • Principal Investigator
      Noritake Kanako
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University

All 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation Book

  • [Book] Autophagy in health and disease2018

    • Author(s)
      Toshihiko Aki, Kanako Noritake, Kana Unuma, Koichi Uemura
    • Total Pages
      18
    • Publisher
      Humana press
    • ISBN
      9783319981451
    • Data Source
      KAKENHI-PROJECT-17H04147
  • [Book] Comprehensive Toxicology 3rd ed Volume 1 (General subjects).2018

    • Author(s)
      Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.
    • Total Pages
      25
    • Publisher
      Elsevier
    • ISBN
      9780081006016
    • Data Source
      KAKENHI-PROJECT-17H04147
  • [Book] Autophagy in health and disease2018

    • Author(s)
      Toshihiko Aki, Kanako Noritake, Kana Unuma, and Koichi Uemura.
    • Total Pages
      192
    • Publisher
      Humana Press
    • ISBN
      9783319981451
    • Data Source
      KAKENHI-PROJECT-17K15879
  • [Book] Comprehensive Toxicology, 3rd Edition2017

    • Author(s)
      Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.
    • Total Pages
      8624
    • Publisher
      Elsevier
    • ISBN
      9780081006016
    • Data Source
      KAKENHI-PROJECT-17K15879
  • [Journal Article] Possible roles of AMPK and macropinocytosis in the defense responses against Δ9-THC toxicity on HL-1 cardiomyocytes2021

    • Author(s)
      Murata Tatsuhiko、Noritake Kanako、Aki Toshihiko、Uemura Koichi
    • Journal Title

      Toxicology Reports

      Volume: 8 Pages: 980-987

    • DOI

      10.1016/j.toxrep.2021.04.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19670, KAKENHI-PROJECT-19K19483
  • [Journal Article] Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells2020

    • Author(s)
      Aki Toshihiko、Funakoshi Takeshi、Noritake Kanako、Unuma Kana、Uemura Koichi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 10581-10581

    • DOI

      10.1038/s41598-020-67396-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03955, KAKENHI-PROJECT-18K19670
  • [Journal Article] Pyroptotic cell death by exposure to 1-butanol in H9c2 cardiomyoblastoma cells2020

    • Author(s)
      Kanako Noritake , Toshihiko Aki , Shintaro Isa , Koichi Uemura
    • Journal Title

      Heliyon

      Volume: 6 Issue: 11 Pages: e05503-e05503

    • DOI

      10.1016/j.heliyon.2020.e05503

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K19483, KAKENHI-PROJECT-18K19670
  • [Journal Article] Formation of high molecular weight p62 by CORM-32019

    • Author(s)
      Aki Toshihiko、Unuma Kana、Noritake Kanako、Hirayama Naho、Funakoshi Takeshi、Uemura Koichi
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 1 Pages: e0210474-e0210474

    • DOI

      10.1371/journal.pone.0210474

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
  • [Journal Article] Necrosis in human neuronal cells exposed to paraquat2018

    • Author(s)
      Naho Hirayama, Toshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura.
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 43 Issue: 3 Pages: 193-202

    • DOI

      10.2131/jts.43.193

    • NAID

      130006507321

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
  • [Journal Article] Interaction of carbon monoxide-releasing ruthenium carbonyl CORM-3 with plasma fibronectin2018

    • Author(s)
      Aki Toshihiko、Unuma Kana、Noritake Kanako、Kurahashi Hatsumi、Funakoshi Takeshi、Uemura Koichi
    • Journal Title

      Toxicology in Vitro

      Volume: 50 Pages: 201-209

    • DOI

      10.1016/j.tiv.2018.03.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
  • [Journal Article] 差分解説:アルコールによる心障害2017

    • Author(s)
      則竹香菜子, 上村公一
    • Journal Title

      日本医事新報

      Volume: 印刷中

    • Data Source
      KAKENHI-PROJECT-15H06182
  • [Journal Article] Restoration of YAP activation rescues HL-1 cardiomyocytes from apoptotic death by ethanol2017

    • Author(s)
      Kanako Noritake, Toshihiko Aki, Moe Kimura, Takeshi Funakoshi, Kana Unuma, Koichi Uemura.
    • Journal Title

      The Journal of Toxicological Sciences

      Volume: 42 Issue: 5 Pages: 545-551

    • DOI

      10.2131/jts.42.545

    • NAID

      130006076729

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15879, KAKENHI-PROJECT-17H04147
  • [Journal Article] Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.2015

    • Author(s)
      Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K.
    • Journal Title

      PLoS One

      Volume: 10(8) Issue: 8 Pages: e0136952-e0136952

    • DOI

      10.1371/journal.pone.0136952

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06182, KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
  • [Journal Article] アルコールによる心筋障害と オートファジーの役割2015

    • Author(s)
      則竹香菜子,秋利彦, 上村公一
    • Journal Title

      月刊「細胞」

      Volume: 47(14) Pages: 44-47

    • Data Source
      KAKENHI-PROJECT-15H06182
  • [Presentation] Fatal Intoxication with a mixture of para-methoxyamphetamine, N-ethylpentylone, and ketamine2022

    • Author(s)
      Kanako Noritake, Kanju Saka, Kana Unuma, Takeshi Funakoshi, Ruri Kikura-Hanajiri, Yohsuke Makino, Hirotaro Iwase, Koichi Uemura
    • Organizer
      59th meeting of The International Association of Forensic Toxicologists (TIAFT)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K19483
  • [Presentation] LPS 刺激マクロファージ様細胞におけるパイロトーシスと一酸化炭素発生剤の抑制作用2020

    • Author(s)
      秋 利彦,船越丈司,佐野智美,則竹香菜子,上村公一
    • Organizer
      第104次日本法医学会学術全国集会、京都府、京都市
    • Data Source
      KAKENHI-PROJECT-20H03955
  • [Presentation] 大麻成分Δ9-THCとアルコールの心筋細胞への影響2020

    • Author(s)
      村田達彦, 則竹香菜子, 秋利彦, 上村公一
    • Organizer
      第55回日本アルコール・アディクション医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K19483
  • [Presentation] エタノール以外のアルコールによる細胞毒性研究2019

    • Author(s)
      則竹香菜子, 秋利彦, 上村公一
    • Organizer
      第55回日本アルコール・アディクション医学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K19483
  • [Presentation] Involvement of microRNA in ethanol-induced cardiotoxicity.2018

    • Author(s)
      Kanako Noritake, Toshihiko Aki, Koichi Uemura.
    • Organizer
      ISBRA 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15879
  • [Presentation] エタノールによる心筋細胞死は YAP 活性化により抑制される.2017

    • Author(s)
      則竹香菜子, 秋 利彦, 上村公一.
    • Organizer
      第52回 日本アルコール・アディクション医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K15879
  • [Presentation] エタノールによる心筋細胞死は YAP 活性化により抑制される2017

    • Author(s)
      則竹香菜子, 秋 利彦, 上村公一
    • Organizer
      第52回 日本アルコール・アディクション医学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04147
  • [Presentation] HL-1心筋細胞においてエタノールは細胞間接着・細胞骨格を破綻し、Hippo経路の機能を障害する2015

    • Author(s)
      則竹香菜子,秋 利彦,上村公一
    • Organizer
      第88回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-15H06182
  • [Presentation] アルコールの毒性と心筋細胞障害2015

    • Author(s)
      則竹香菜子,秋 利彦,上村公一
    • Organizer
      第50回日本アルコール・薬物医学会
    • Place of Presentation
      神戸国際会議場(兵庫県・神戸市)
    • Year and Date
      2015-10-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06182
  • 1.  Aki Toshihiko (60304474)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 2.  船越 丈司 (40444715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  鵜沼 香奈 (30586425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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