Noritake Kanako 則竹香菜子

Researcher Number	40758067
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 学術専門職員
Affiliation (based on the past Project Information) *help	2022: 東京医科歯科大学, 大学院医歯学総合研究科, 特任助教 2020 – 2022: 東京大学, 大学院医学系研究科(医学部), 特任研究員 2016 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 特任助教 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 特任助教
Review Section/Research Field	Principal Investigator Legal medicine / Basic Section 58040:Forensics medicine-related Except Principal Investigator Basic Section 58040:Forensics medicine-related / Legal medicine
Keywords	Principal Investigator エタノール / 心筋細胞 / 心筋障害 / Hippo-YAP経路 / 毒性機序 / Δ9-テトラヒドロカンナビノール / 小胞体ストレス / AMPK / マクロピノサイトーシス / ERストレス … More / Δ9-THC / microRNA / YAP / 心筋細胞障害 / アルコール / 細胞間接着分子 / 細胞間接着 / 心筋細胞傷害 … More Except Principal Investigator 法医学 / 代謝物 / 解糖系 / 細胞死 / 代謝産物 / 免疫細胞 / 炎症 / グルコース / 炎症性細胞死 / アセトアミノフェン / ガスダーミン / ヒ素 / 代謝 / マクロファージ / パイロトーシス / 法医病理 / プロテオーム / ヘム / タンパク質凝集体 / ミトコンドリア / プロテオミクス / メタボロミクス / 硫化水素 / p62 / フィブロネクチン / CORM-3 / 一酸化炭素 Less

Regulation mechanism of pyroptosis by metabolites
- Principal Investigator
  
  Aki Toshihiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Tokyo Medical and Dental University
The molecular mechanism of direct cardiotoxicity of cannabinoid, and the effect of ethanolPrincipal Investigator
- Principal Investigator
  
  Noritake Kanako
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  The University of Tokyo
  Tokyo Medical and Dental University
Involvement of YAP inactivation and microRNA in ethanol-induced cardiotoxicityPrincipal Investigator
- Principal Investigator
  
  Noritake Kanako
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
Analysis of carbon monoxide toxicity using water-soluble CORMs
- Principal Investigator
  
  Aki Toshihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University
The role of Hippo-YAP pathway in alcohol-induced cardiac dysfunctionPrincipal Investigator
- Principal Investigator
  
  Noritake Kanako
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Legal medicine
- Research Institution
  Tokyo Medical and Dental University

All 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation Book

[Book] Autophagy in health and disease2018
- Author(s)
  Toshihiko Aki, Kanako Noritake, Kana Unuma, Koichi Uemura
- Total Pages
  18
- Publisher
  Humana press
- ISBN
  9783319981451
- Data Source
  KAKENHI-PROJECT-17H04147
[Book] Comprehensive Toxicology 3rd ed Volume 1 (General subjects).2018
- Author(s)
  Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.
- Total Pages
  25
- Publisher
  Elsevier
- ISBN
  9780081006016
- Data Source
  KAKENHI-PROJECT-17H04147
[Book] Autophagy in health and disease2018
- Author(s)
  Toshihiko Aki, Kanako Noritake, Kana Unuma, and Koichi Uemura.
- Total Pages
  192
- Publisher
  Humana Press
- ISBN
  9783319981451
- Data Source
  KAKENHI-PROJECT-17K15879
[Book] Comprehensive Toxicology, 3rd Edition2017
- Author(s)
  Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura.
- Total Pages
  8624
- Publisher
  Elsevier
- ISBN
  9780081006016
- Data Source
  KAKENHI-PROJECT-17K15879
[Journal Article] Possible roles of AMPK and macropinocytosis in the defense responses against Δ9-THC toxicity on HL-1 cardiomyocytes2021
- Author(s)
  Murata Tatsuhiko、Noritake Kanako、Aki Toshihiko、Uemura Koichi
- Journal Title
  
  Toxicology Reports
  
  Volume: 8 Pages: 980-987
- DOI
  10.1016/j.toxrep.2021.04.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19670, KAKENHI-PROJECT-19K19483
[Journal Article] Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells2020
- Author(s)
  Aki Toshihiko、Funakoshi Takeshi、Noritake Kanako、Unuma Kana、Uemura Koichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 10581-10581
- DOI
  10.1038/s41598-020-67396-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03955, KAKENHI-PROJECT-18K19670
[Journal Article] Pyroptotic cell death by exposure to 1-butanol in H9c2 cardiomyoblastoma cells2020
- Author(s)
  Kanako Noritake , Toshihiko Aki , Shintaro Isa , Koichi Uemura
- Journal Title
  
  Heliyon
  
  Volume: 6 Issue: 11 Pages: e05503-e05503
- DOI
  10.1016/j.heliyon.2020.e05503
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19483, KAKENHI-PROJECT-18K19670
[Journal Article] Formation of high molecular weight p62 by CORM-32019
- Author(s)
  Aki Toshihiko、Unuma Kana、Noritake Kanako、Hirayama Naho、Funakoshi Takeshi、Uemura Koichi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 1 Pages: e0210474-e0210474
- DOI
  10.1371/journal.pone.0210474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] Necrosis in human neuronal cells exposed to paraquat2018
- Author(s)
  Naho Hirayama, Toshihiko Aki, Takeshi Funakoshi, Kanako Noritake, Kana Unuma, Koichi Uemura.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 43 Issue: 3 Pages: 193-202
- DOI
  10.2131/jts.43.193
- NAID
  130006507321
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] Interaction of carbon monoxide-releasing ruthenium carbonyl CORM-3 with plasma fibronectin2018
- Author(s)
  Aki Toshihiko、Unuma Kana、Noritake Kanako、Kurahashi Hatsumi、Funakoshi Takeshi、Uemura Koichi
- Journal Title
  
  Toxicology in Vitro
  
  Volume: 50 Pages: 201-209
- DOI
  10.1016/j.tiv.2018.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04147, KAKENHI-PROJECT-16K09203
[Journal Article] 差分解説：アルコールによる心障害2017
- Author(s)
  則竹香菜子, 上村公一
- Journal Title
  
  日本医事新報
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-15H06182
[Journal Article] Restoration of YAP activation rescues HL-1 cardiomyocytes from apoptotic death by ethanol2017
- Author(s)
  Kanako Noritake, Toshihiko Aki, Moe Kimura, Takeshi Funakoshi, Kana Unuma, Koichi Uemura.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 42 Issue: 5 Pages: 545-551
- DOI
  10.2131/jts.42.545
- NAID
  130006076729
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15879, KAKENHI-PROJECT-17H04147
[Journal Article] Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.2015
- Author(s)
  Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K.
- Journal Title
  
  PLoS One
  
  Volume: 10(8) Issue: 8 Pages: e0136952-e0136952
- DOI
  10.1371/journal.pone.0136952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06182, KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
[Journal Article] アルコールによる心筋障害とオートファジーの役割2015
- Author(s)
  則竹香菜子，秋利彦，上村公一
- Journal Title
  
  月刊「細胞」
  
  Volume: 47(14) Pages: 44-47
- Data Source
  KAKENHI-PROJECT-15H06182
[Presentation] Fatal Intoxication with a mixture of para-methoxyamphetamine, N-ethylpentylone, and ketamine2022
- Author(s)
  Kanako Noritake, Kanju Saka, Kana Unuma, Takeshi Funakoshi, Ruri Kikura-Hanajiri, Yohsuke Makino, Hirotaro Iwase, Koichi Uemura
- Organizer
  59th meeting of The International Association of Forensic Toxicologists (TIAFT)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19483
[Presentation] LPS 刺激マクロファージ様細胞におけるパイロトーシスと一酸化炭素発生剤の抑制作用2020
- Author(s)
  秋利彦，船越丈司，佐野智美，則竹香菜子，上村公一
- Organizer
  第104次日本法医学会学術全国集会、京都府、京都市
- Data Source
  KAKENHI-PROJECT-20H03955
[Presentation] 大麻成分Δ9-THCとアルコールの心筋細胞への影響2020
- Author(s)
  村田達彦, 則竹香菜子, 秋利彦, 上村公一
- Organizer
  第55回日本アルコール・アディクション医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K19483
[Presentation] エタノール以外のアルコールによる細胞毒性研究2019
- Author(s)
  則竹香菜子, 秋利彦, 上村公一
- Organizer
  第55回日本アルコール・アディクション医学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K19483
[Presentation] Involvement of microRNA in ethanol-induced cardiotoxicity.2018
- Author(s)
  Kanako Noritake, Toshihiko Aki, Koichi Uemura.
- Organizer
  ISBRA 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15879
[Presentation] エタノールによる心筋細胞死は YAP 活性化により抑制される.2017
- Author(s)
  則竹香菜子, 秋　利彦, 上村公一.
- Organizer
  第52回日本アルコール・アディクション医学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15879
[Presentation] エタノールによる心筋細胞死は YAP 活性化により抑制される2017
- Author(s)
  則竹香菜子, 秋　利彦, 上村公一
- Organizer
  第52回日本アルコール・アディクション医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04147
[Presentation] HL-1心筋細胞においてエタノールは細胞間接着・細胞骨格を破綻し、Hippo経路の機能を障害する2015
- Author(s)
  則竹香菜子，秋利彦，上村公一
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15H06182
[Presentation] アルコールの毒性と心筋細胞障害2015
- Author(s)
  則竹香菜子，秋利彦，上村公一
- Organizer
  第50回日本アルコール・薬物医学会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-10-12
- Invited
- Data Source
  KAKENHI-PROJECT-15H06182

1. Aki Toshihiko (60304474)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. 船越丈司 (40444715)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 鵜沼香奈 (30586425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Noritake Kanako 則竹 香菜子

Research Projects

Research Products

Co-Researchers

Regulation mechanism of pyroptosis by metabolites

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The molecular mechanism of direct cardiotoxicity of cannabinoid, and the effect of ethanolPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of YAP inactivation and microRNA in ethanol-induced cardiotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of carbon monoxide toxicity using water-soluble CORMs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Hippo-YAP pathway in alcohol-induced cardiac dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Autophagy in health and disease2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] Comprehensive Toxicology 3rd ed Volume 1 (General subjects).2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] Autophagy in health and disease2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] Comprehensive Toxicology, 3rd Edition2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Possible roles of AMPK and macropinocytosis in the defense responses against Δ9-THC toxicity on HL-1 cardiomyocytes2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pyroptotic cell death by exposure to 1-butanol in H9c2 cardiomyoblastoma cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Formation of high molecular weight p62 by CORM-32019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Necrosis in human neuronal cells exposed to paraquat2018

Author(s)

Noritake Kanako 則竹香菜子

[Journal Article] アルコールによる心筋障害とオートファジーの役割2015