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ISHIDA Waka  石田 わか

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Ishida Waka  石田 わか

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Researcher Number 40761705
Other IDs
Affiliation (Current) 2025: 高知大学, 医学部, 特任助教
Affiliation (based on the past Project Information) *help 2017 – 2024: 高知大学, 医学部, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 56060:Ophthalmology-related
Except Principal Investigator
Basic Section 56060:Ophthalmology-related / Ophthalmology
Keywords
Principal Investigator
アトピー性角結膜炎 / アレルギー / アレルギー性結膜炎
Except Principal Investigator
眼内炎 / DAMPs / 黄色ブドウ球菌 / 病的近視 / IL8 / IL6 / IL1 … More / CCDC102B / CCDC102A / VEGF / ARPE19 / HUVEC / バクテリオファージ / 感染症 / psm-α / ブドウ球菌 / phenol-soluble modulin α / アラーミン / IL-36 / 角膜炎 / メチシリン耐性黄色ブドウ球菌 / フェノール可溶性モジュリンα / 細胞・組織 / アレルギー・ぜんそく / 粘膜型マスト細胞 / 結合組織型マスト細胞 / P2X7受容体 / 濾過手術 / 瘢痕化 / ブレブ / matrix metalloprotainase / コラーゲンゲル / 結膜線維芽細胞 / 創傷治癒 / 結膜 / 線維芽細胞 / 組織特異性 / マスト細胞 Less
  • Research Projects

    (6 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (8 People)
  •  アトピー性角結膜炎の発症および重症化における黄色ブドウ球菌と自然免疫応答の解析Principal Investigator

    • Principal Investigator
      石田 わか
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kochi University
  •  黄色ブドウ球菌眼内炎におけるDAMPsによる炎症制御機構の解明および治療法の開発

    • Principal Investigator
      福田 憲
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kochi University
  •  Establishment of preventive methods for blindness due to pathologic myopia by targeting CCDC102B

    • Principal Investigator
      山城 健児
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kochi University
  •  Investigation of the effects of PSMalpha and phage therapy in Staphylococcus aureus keratitis

    • Principal Investigator
      Fukuda Ken
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kochi University
  •  Non-IgE-mediated allergic conjunctivitis induced by endotoxin and allergen in mice.Principal Investigator

    • Principal Investigator
      Ishida Waka
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kochi University
  •  Investigation of the differentiation mechanism of ocular tissue-specific mast cells and its involvement in wound healing

    • Principal Investigator
      FUKUDA Ken
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Kochi University

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Staphylococcus aureus-derived virulent phenol-soluble modulin α triggers alarmin release to drive IL-36-dependent corneal inflammation2024

    • Author(s)
      Nakajima Isana、Fukuda Ken、Ishida Waka、Kishimoto Tatsuma、Kuwana Aozora、Suzuki Takashi、Kaito Chikara、Yamashiro Kenji
    • Journal Title

      Microbes and Infection

      Volume: 26 Issue: 1-2 Pages: 105237-105237

    • DOI

      10.1016/j.micinf.2023.105237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09744, KAKENHI-PROJECT-22K19435, KAKENHI-PROJECT-21K16896, KAKENHI-PROJECT-23K24131
  • [Journal Article] Intracameral Bacteriophage Injection as Postoperative Prophylaxis for Enterococcus faecalis Induced Endophthalmitis After Cataract Surgery in Rabbits2022

    • Author(s)
      Kishimoto Tatsuma、Ishida Waka、Nakajima Isana、Ujihara Takako、Suzuki Takashi、Uchiyama Jumpei、Matsuzaki Shigenobu、Fukuda Ken
    • Journal Title

      Translational Vision Science & Technology

      Volume: 11 Issue: 4 Pages: 2-2

    • DOI

      10.1167/tvst.11.4.2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09744, KAKENHI-PROJECT-22K08580, KAKENHI-PROJECT-22K08593
  • [Journal Article] Aqueous-Deficient Dry Eye Exacerbates Signs and Symptoms of Allergic Conjunctivitis in Mice2022

    • Author(s)
      Kishimoto Tatsuma、Ishida Waka、Nakajima Isana、Fukuda Ken、Yamashiro Kenji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 9 Pages: 4918-4918

    • DOI

      10.3390/ijms23094918

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09744, KAKENHI-PROJECT-21K16896, KAKENHI-PROJECT-20K18346
  • [Journal Article] Promotion of conjunctival fibroblast-mediated collagen gel contraction by mast cells through up-regulation of matrix metalloproteinase release and activation2022

    • Author(s)
      Kishimoto Tatsuma、Ishida Waka、Nakajima Isana、Taguchi Osamu、Sugioka Koji、Kusaka Shunji、Fukuda Ken
    • Journal Title

      Experimental Eye Research

      Volume: 218 Pages: 108980-108980

    • DOI

      10.1016/j.exer.2022.108980

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09744, KAKENHI-PROJECT-21K16896, KAKENHI-PROJECT-20K18346
  • [Journal Article] Role of Damage-Associated Molecular Patterns (DAMPs/Alarmins) in Severe Ocular Allergic Diseases2022

    • Author(s)
      Fukuda Ken、Ishida Waka、Kishimoto Tatsuma、Nakajima Isana、Miura Yusaku、Sumi Tamaki、Yamashiro Kenji
    • Journal Title

      Cells

      Volume: 11 Issue: 6 Pages: 1051-1051

    • DOI

      10.3390/cells11061051

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09744, KAKENHI-PROJECT-21K16896, KAKENHI-PROJECT-20K18346
  • [Journal Article] Pivotal Role of Corneal Fibroblasts in Progression to Corneal Ulcer in Bacterial Keratitis2021

    • Author(s)
      Nishida Teruo、Sugioka Koji、Fukuda Ken、Murakami Junko
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 16 Pages: 8979-8979

    • DOI

      10.3390/ijms22168979

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09744
  • [Journal Article] Prophylactic and Therapeutic Effects of Oral Immunotherapy on Birch Pollen-Induced Allergic Conjunctivitis in Mice with a Rice-Based Edible Vaccine Expressing a Hypoallergenic Birch Pollen Allergen2021

    • Author(s)
      Ishida Waka、Kishimoto Tatsuma、Takaiwa Fumio、Fukuda Ken
    • Journal Title

      Cells

      Volume: 10 Issue: 12 Pages: 3361-3361

    • DOI

      10.3390/cells10123361

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09744, KAKENHI-PROJECT-21K16896
  • [Journal Article] Therapeutic Effects of Intravitreously Administered Bacteriophage in a Mouse Model of Endophthalmitis Caused by Vancomycin-Sensitive or -Resistant Enterococcus faecalis2019

    • Author(s)
      Kishimoto Tatsuma、Ishida Waka、Fukuda Ken、Nakajima Isana、Suzuki Takashi、Uchiyama Jumpei、Matsuzaki Shigenobu、Todokoro Daisuke、Daibata Masanori、Fukushima Atsuki
    • Journal Title

      Antimicrobial Agents and Chemotherapy

      Volume: 63 Issue: 11

    • DOI

      10.1128/aac.01088-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07127, KAKENHI-PROJECT-19K08953, KAKENHI-PROJECT-17K11453
  • [Journal Article] Development of conjunctivitis with a conjunctival proliferative lesion in a patient treated with dupilumab for atopic dermatitis2019

    • Author(s)
      Fukuda K, Ishida W, Kishimoto T, Fukushima A.
    • Journal Title

      Allergol. Int.

      Volume: 68 Issue: 3 Pages: 383-384

    • DOI

      10.1016/j.alit.2018.12.012

    • NAID

      130007678526

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Journal Article] 低アレルゲン性スギ花粉アレルゲンを含む米によるアレルギー性結膜炎モデルマウスの経口免疫療法2019

    • Author(s)
      福田 憲、石田わか
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 71 Pages: 1-5

    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Journal Article] Evaluation of offset of conjunctival hyperemia induced by a Rho-kinase inhibitor; 0.4% Ripasudil ophthalmic solution clinical trial.2019

    • Author(s)
      Sakamoto E, Ishida W , Sumi T, Kishimoto T, Tada K, Fukuda K, Yoneda T, Kuroiwa H, Terao E, Fujisawa Y, Nakakura S, Jian K, Okumichi H, Kiuchi Y, Fukushima A.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 3755-3755

    • DOI

      10.1038/s41598-019-40255-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11453, KAKENHI-PROJECT-17K11482
  • [Journal Article] Periostin deletion suppresses late-phase response in mouse experimental allergic conjunctivitis2019

    • Author(s)
      Asada Y, Okano M, Ishida W, Iwamoto S, Fukuda K, Hirakata T, Tada N, Fukushima A, Ebihara N, Kudo A, Matsuda A.
    • Journal Title

      Allergol. Int.

      Volume: 68 Issue: 2 Pages: 233-239

    • DOI

      10.1016/j.alit.2018.09.007

    • NAID

      130007633580

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11453, KAKENHI-PROJECT-16K11303, KAKENHI-PROJECT-26430207, KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-19K09980, KAKENHI-PROJECT-19K18891, KAKENHI-PROJECT-19K23851
  • [Journal Article] Efficacy of oral immunotherapy with a rice-based edible vaccine containing hypoallergenic Japanese cedar pollen allergens for treatment of established allergic conjunctivitis in mice2018

    • Author(s)
      Fukuda Ken、Ishida Waka、Harada Yosuke、Wakasa Yuhya、Takagi Hidenori、Takaiwa Fumio、Fukushima Atsuki
    • Journal Title

      Allergol. Int.

      Volume: 67 Issue: 1 Pages: 119-123

    • DOI

      10.1016/j.alit.2017.06.006

    • NAID

      130006322022

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11453, KAKENHI-PROJECT-16K11324
  • [Journal Article] Oral Immunotherapy for Allergic Conjunctivitis Using Transgenic Rice Expressing Hypoallergenic Antigens.2018

    • Author(s)
      Fukuda K, Ishida W, Wakasa Y, Takagi H, Takaiwa F, Fukushima A.
    • Journal Title

      Cornea. 2018 Nov;37 Suppl 1:S67-S73.

      Volume: 37 Issue: 1 Pages: S67-S73

    • DOI

      10.1097/ico.0000000000001758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Journal Article] Cytokine expression and barrier disruption in human corneal epithelial cells induced by alarmin released from necrotic cells.2017

    • Author(s)
      Fukuda K, Ishida W, Miura Y, Kishimoto T, Fukushima A.
    • Journal Title

      Jpn J Ophthalmol

      Volume: 61 Issue: 5 Pages: 415-422

    • DOI

      10.1007/s10384-017-0528-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11324, KAKENHI-PROJECT-17K11453
  • [Journal Article] Corneal Fibroblasts as Sentinel Cells and Local Immune Modulators in InfectiousKeratitis.2017

    • Author(s)
      Fukuda K, Ishida W, Fukushima A, Nishida T.
    • Journal Title

      Int J Mol Sci

      Volume: 18(9) Issue: 9 Pages: 1831-1831

    • DOI

      10.3390/ijms18091831

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11324, KAKENHI-PROJECT-17K11453
  • [Journal Article] Contributions of Intreleukin-33 and TSLP in a papain-soaked contact lens-induced mouse conjunctival Inflammation model.2017

    • Author(s)
      Sugita J, Asada Y , Ishida W, Iwamoto S, Sudo K, Suto H, Matsunaga T, Fukuda K, Fukushima A, Yokoi N, Ohno T, Azuma M, Ebihara N, Saito H, Kubo M, Nakae S, Matsuda A.
    • Journal Title

      Immunity, Inflammation and Disease.

      Volume: 5(4) Issue: 4 Pages: 515-525

    • DOI

      10.1002/iid3.189

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11324, KAKENHI-PROJECT-17K11453, KAKENHI-PROJECT-16H07189, KAKENHI-PROJECT-16K20333
  • [Presentation] 黄色ブドウ球菌由来毒素PSMαによるマウス角膜炎におけるIL-36の関与2023

    • Author(s)
      中島勇魚, 石田わか, 岸本達真, 鈴木崇, 福田 憲, 山城健児
    • Organizer
      角膜カンファランス2023
    • Data Source
      KAKENHI-PROJECT-21K09744
  • [Presentation] 黄色ブドウ球菌由来毒素psmαによるマウス角膜炎の解析2022

    • Author(s)
      中島勇魚, 石田わか, 岸本達真, 鈴木崇, 福田 憲, 山城健児
    • Organizer
      第55回日本眼炎症学会
    • Data Source
      KAKENHI-PROJECT-21K09744
  • [Presentation] 黄色ブドウ球菌由来PSMαによる角膜細胞におけるアラーミン放出2021

    • Author(s)
      中島勇魚, 石田わか, 岸本達真, 鈴木 崇, 福田 憲
    • Organizer
      第57回日本眼感染症学会
    • Data Source
      KAKENHI-PROJECT-21K09744
  • [Presentation] Staphylococcus aureus virulent PSMα induces alarmin release in corneal cells.2021

    • Author(s)
      Nakajima I, Ishida W, Kishimoto T, Suzuki T, Fukuda K
    • Organizer
      The 7th Asia Cornea Society Biennial Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09744
  • [Presentation] 重症アレルギー性結膜疾患の病態と治療2019

    • Author(s)
      福田 憲、石田わか、岸本達真、中島勇魚、角 環、福島敦樹
    • Organizer
      第68回日本アレルギー学会学術大会 シンポジウム22
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Presentation] Therapeutic effects of intravitreous bacteriophage on Enterococcus faecalis endophthalmitis in mice.2019

    • Author(s)
      Fukuda K, Kishimoto T, Ishida W, Suzuki T, Uchiyama J, Matsuzaki S, Daibata M, Fukushima A.
    • Organizer
      ARVO 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Presentation] Therapeutic effects of intravitreous bacteriophage on Enterococcus faecalis endophthalmitis in mice2019

    • Author(s)
      Fukuda K, Kishimoto T, Ishida W, Suzuki T, Uchiyama J, Matsuzaki S, Daibata M, Fukushima A
    • Organizer
      ARVO 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Presentation] Therapeutic effects of bacteriophage φef24c-p2 on Enterococcus faecalis endophthalmitis in mice.2018

    • Author(s)
      Fukuda K, Kishimoto T, Ishida W, Suzuki T, Uchiyama J, Matsuzaki S, Daibata M, Fukushima A.
    • Organizer
      5th World Congress on Targeting Infectious Diseases, Targeting Phage & Antibiotic Resistance
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Presentation] The involvement of Interleukin-10 on the early-phase reaction in the experimental allergic conjunctivitis in a murine model2017

    • Author(s)
      Waka Ishida, Ken Fukuda, Yosuke Harada, Osamu Taguchi, Atsuki Fukushima.
    • Organizer
      The European Academy of Allergy and Clinical Immunology Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11453
  • [Presentation] Mast cells promote collagen lattice contraction mediated by conjunctival fibroblasts by up-regulating matrix metalloproteinase production2017

    • Author(s)
      Tatsuma Kishimoto, Ken Fukuda, Waka Ishida, Atsuki Fukushima
    • Organizer
      The European Academy of Allergy and Clinical Immunology Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11453
  • 1.  FUKUDA Ken (70335751)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 20 results
  • 2.  岸本 達真 (60783751)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 3.  山城 健児 (80399617)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  松崎 茂展 (00190439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  鈴木 崇 (70398048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  海老原 伸行 (20255699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  内山 淳平 (20574619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  福島 敦樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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