Hitora Natsuko 人羅菜津子

… Alternative Names

HITORA Natsuko 人羅菜津子

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Researcher Number	40762191
Other IDs	https://orcid.org/0009-0009-3227-3904
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(薬), 講師
Affiliation (based on the past Project Information) *help	2025: 熊本大学, 大学院生命科学研究部(薬), 講師 2023: 熊本大学, 大学院生命科学研究部(薬), 講師 2023: 熊本大学, 大学院生命科学研究部, 講師 2021 – 2022: 熊本大学, 大学院生命科学研究部附属グローバル天然物科学研究センター, 特任助教 2016 – 2020: 北海道大学, 薬学研究院, 助教 2015: 北海道大学, 大学院薬学研究院, 助教 2015: 北海道大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 51020:Cognitive and brain science-related / Complex systems / Transformative Research Areas, Section (IV) / Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience / Pharmacology in pharmacy Except Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Pain science
Keywords	Principal Investigator 神経科学 / 光遺伝学 / 記憶学習 / 不安障害 / 記憶・学習 / ファイバーフォトメトリー法 / 情動 / カルシウムイメージング / うつ / 意思決定 … More / 葛藤行動 / 精神疾患 / ドパミン / 再発 / 行動薬理学 / 脳・神経 / 神経回路 … More Except Principal Investigator スクリーニング / タンパク質分解 / α-synuclein / 活性化 / 真菌 / 活性化物質 / プロテアソーム / 天然物 / LPS / 多価不飽和脂肪酸 / 炎症 / mTOR / 抗うつ / 慢性疼痛 / ω-3 系脂肪酸 / ω-3系脂肪酸 / 不快情動 / 不安 / 抑うつ / 痛み / レゾルビン Less

可塑性を利用したうつ病予防法の開発に向けた、原因神経回路の解明Principal Investigator
- Principal Investigator
  
  人羅菜津子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kumamoto University
葛藤下での行動選択のマルチセルラメカニズム解明Principal Investigator
- Principal Investigator
  
  人羅菜津子
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Kumamoto University
α-synucleinの分解促進・凝集阻害作用を示す天然物の探索
- Principal Investigator
  
  人羅勇気
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kumamoto University
異なる神経経路が行動を両方向に制御するメカニズムの解明Principal Investigator
- Principal Investigator
  
  人羅菜津子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kumamoto University
Elucidating neural mechanisms to overcome fearPrincipal Investigator
- Principal Investigator
  
  Hitora Natsuko
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kumamoto University
  Hokkaido University
意志力を司る細胞集団メカニズムの解明Principal Investigator
- Principal Investigator
  
  人羅菜津子
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Elucidating neural activity to improve treatment of anxiety disorders.Principal Investigator
- Principal Investigator
  
  Hitora-Imamura Natsuko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Hokkaido University
正と負の意志の動的平衡を担う神経活動の解明Principal Investigator
- Principal Investigator
  
  人羅菜津子
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Effects of resolvins and their mechanism of action on the sensory and emotional components of pain
- Principal Investigator
  
  Satoh Masamichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Kyoto University
Role of VTA-PFC circuit in an animal model of anxiety disordersPrincipal Investigator
- Principal Investigator
  
  HITORA Natsuko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Evaluation of behavioural selection processes in conflict scenarios using a newly developed mouse behavioural paradigm2023
- Author(s)
  Miyagami Yurika、Honshuku Yuki、Nomura Hiroshi、Minami Masabumi、Hitora-Imamura Natsuko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 20006-20006
- DOI
  10.1038/s41598-023-46743-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16248
[Journal Article] Syrosingopine Enhances 20S Proteasome Activity and Degradation of α-Synuclein2023
- Author(s)
  Sadahiro Yusaku、Nishimura Soichiro、Hitora Yuki、Tsukamoto Sachiko
- Journal Title
  
  Journal of Natural Products
  
  Volume: 87 Issue: 3 Pages: 554-559
- DOI
  10.1021/acs.jnatprod.3c00661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06679, KAKENHI-PROJECT-21K19341
[Journal Article] M. Minami, Resolvin E1 and E2 ameliorate lipopolysaccharide-induced depression-like behaviors via ChemR232017
- Author(s)
  K. Deyama, Y. Shimoda, K. Ishikawa, H. Ishimura, H. Fukuda, S. Ide, M. Satoh, S. Shuto
- Journal Title
  
  Psychopharmacology
  
  Volume: 235 Issue: 1 Pages: 329-336
- DOI
  10.1007/s00213-017-4774-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-15K06765, KAKENHI-PROJECT-15K08670
[Presentation] Bioactive molecular networkingを利用した真菌由来20Sプロテアソーム活性化物質の探索2024
- Author(s)
  貞廣優作, 人羅勇気, 本田公洋, 手島徳哉, 長野由梨子, 塚本佐知子
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K06679
[Presentation] マウスの3コンパートメント葛藤課題における接近・回避行動の評価2023
- Author(s)
  人羅（今村）菜津子、本宿雄基、宮上祐里香、森翠、野村洋、南雅文
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K07329
[Presentation] 子育て世代が Win-Win を目指せる環境とは2023
- Author(s)
  人羅（今村）菜津子
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07329
[Presentation] 天然物からの 20S プロテアソーム活性化物質の探索と syrosingopine の作用に関する研究2023
- Author(s)
  貞廣優作, 西村宗一郎, 人羅勇気, 塚本佐知子
- Organizer
  第24回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06679
[Presentation] 細胞試験系を用いたプロテアソーム活性化作用を示す天然物の探索とレセルピン類の活性について2022
- Author(s)
  人羅勇気, 西村宗一郎, 塚本佐知子
- Organizer
  第9回食品薬学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06679
[Presentation] Activation of neural projection from the medial prefrontal cortex to the periaqueductal gray facilitates overcoming fear in a conflict context2022
- Author(s)
  本宿雄基、曽我卓司、齋藤瞭毅、宮上祐里佳、森翠、野村洋、南雅文、香月博志、人羅(今村)菜津子
- Organizer
  第45回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K16248
[Presentation] 脳活動計測から紐解く意志力の制御機構2021
- Author(s)
  人羅（今村）菜津子
- Organizer
  第94回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05002
[Presentation] A cortical-brainstem circuit facilitates overcoming fear.2021
- Author(s)
  本宿雄基, 齋藤瞭毅, 曽我卓司, 宮上祐里佳, 森翠, 野村洋, 南雅文, 人羅(今村)菜津子
- Organizer
  第44回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16248
[Presentation] 恐怖を乗り越える神経回路メカニズムの解明2021
- Author(s)
  本宿雄基, 齋藤瞭毅, 曽我卓司, 宮上祐里佳, 森翠, 野村洋, 南雅文, 人羅ー今村菜津子
- Organizer
  第34回北海道薬物作用談話会
- Data Source
  KAKENHI-PROJECT-19K16248
[Presentation] 葛藤環境での行動選択に関する前帯状皮質から中脳水道周囲灰白質への神経投射メカニズム2021
- Author(s)
  本宿雄基、齋藤瞭毅、曽我卓司、南雅文、人羅（今村）菜津子
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K14926
[Presentation] 葛藤環境における報酬探索行動を促進する大脳皮質-脳幹回路2021
- Author(s)
  人羅（今村）菜津子、本宿雄基、齋藤瞭毅、曽我卓司、野村洋、南雅文
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K16248
[Presentation] 葛藤環境における接近・回避行動の解析2021
- Author(s)
  宮上祐里佳、南雅文、人羅（今村）菜津子
- Organizer
  第30回神経行動薬理若手研究者の集い
- Data Source
  KAKENHI-PROJECT-19K16248
[Presentation] 葛藤行動試験系の構築と抗不安薬投与による影響2021
- Author(s)
  宮上祐里佳, 南雅文, 人羅(今村)菜津子
- Organizer
  第72回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-19K16248
[Presentation] 葛藤環境での行動選択における内側前頭前皮質ー中脳水道周囲灰白質経路の機能解明2020
- Author(s)
  本宿雄基,人羅(今村) 菜津子、齋藤瞭毅、曽我卓司、南雅文
- Organizer
  第140回日本薬学会
- Data Source
  KAKENHI-PUBLICLY-19H05002
[Presentation] カルシウム感受性蛍光タンパク質を用いた in vivo 神経活動計測2019
- Author(s)
  人羅（今村）菜津子
- Organizer
  第92年会日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K14926
[Presentation] 内側前頭前皮質－中脳水道周囲灰白質経路による葛藤環境での行動制御機構2019
- Author(s)
  人羅(今村) 菜津子、齋藤瞭毅、曽我卓司、野村洋、南雅文
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PUBLICLY-17H06043
[Presentation] 内側前頭前皮質から中脳水道周囲灰白質への神経投射は葛藤環境における報酬探索行動を促進する2019
- Author(s)
  本宿雄基、齋藤瞭毅、曽我卓司、南雅文、人羅(今村)菜津子
- Organizer
  第49回日本神経精神薬理学会
- Data Source
  KAKENHI-PUBLICLY-19H05002
[Presentation] Top-down control of mouse exploratory behaviors2018
- Author(s)
  Natsuko Hitora-Imamura , Ryoki Saito, Hikaru Igarashi, Daiki Takahashi, Yuji Ikegaya, Masabumi Minami, Hiroshi Nomura
- Organizer
  GRC, Optogenetics and Imaging: Technology Development, Novel Applications, and Closing the Loop Between Models and Experiments
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14926
[Presentation] レゾルビンE1およびレゾルビンE2の抗うつ作用機序2018
- Author(s)
  鈴木博惠、出山諭司、霜田健斗、石川由香、石村航平、福田隼、人羅（今村）菜津子、井手聡一郎、佐藤公道、金田勝幸、周東智、南雅文
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-15K08670
[Presentation] Neural projection dynamics underlying motivated behaviors in a conflicting context2018
- Author(s)
  Natsuko Hitora-Imamura, Takuji Soga, Masabumi Minami
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06043
[Presentation] Neuronal circuit activities underlying conflict decision making in fearful situations2017
- Author(s)
  Natsuko Hitora-Imamura, Yuki Miura, Chie Teshirogi, Yuji Ikegaya, Norio Matsuki, Masabumi Minami, Hiroshi Nomura
- Organizer
  第44回内藤コンファレンス
- Data Source
  KAKENHI-PUBLICLY-17H06043
[Presentation] 前帯状皮質から中脳水道周囲灰白質への神経投射の活性化はマウスの探索行動を増大させる2017
- Author(s)
  齋藤瞭毅、人羅(今村) 菜津子、五十嵐ひかる、高橋大樹、池谷裕二、南雅文、野村洋
- Organizer
  第40回日本神経科学学会
- Data Source
  KAKENHI-PUBLICLY-17H06043
[Presentation] 前帯状皮質から中脳水道周囲灰白質への神経投射の活性化はマウスの探索行動を増大させる2017
- Author(s)
  齋藤瞭毅、人羅(今村) 菜津子、五十嵐ひかる、高橋大樹、池谷裕二、南雅文、野村洋
- Organizer
  第40回日本神経科学学会
- Data Source
  KAKENHI-PROJECT-17K14926
[Presentation] Neuronal circuit activities underlying conflict decision making in fearful situations2017
- Author(s)
  Natsuko Hitora-Imamura, Yuki Miura, Chie Teshirogi, Yuji Ikegaya, Norio Matsuki, Masabumi Minami, Hiroshi Nomura
- Organizer
  第44回内藤コンファレンス
- Data Source
  KAKENHI-PROJECT-17K14926
[Presentation] レゾルビンD1、D2の抗うつ作用メカニズムの解明2016
- Author(s)
  石川由香、出山諭司、吉川琴美、霜田健斗、井手聡一郎、人羅（今村）菜津子、佐藤公道、南雅文
- Organizer
  第38回日本生物学的精神医学会、第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-15K08670
[Presentation] Prevention of fear re-appearance by blockage of dopamine signaling2016
- Author(s)
  Natsuko Hitora-Imamura, Yuki Miura, Chie Teshirogi, Yuji Ikegaya, Norio Matsuki, Hiroshi Nomura
- Organizer
  The 15th Annual Molecular and Cellular Cognition Society Meeting
- Place of Presentation
  San Diego (アメリカ)
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05995
[Presentation] Prevention of fear re-appearance by blockage of dopamine signaling2016
- Author(s)
  Natsuko Hitora-Imamura, Yuki Miura, Chie Teshirogi, Yuji Ikegaya, Norio Matsuki, Hiroshi Nomura
- Organizer
  The 46th Annual Meeting of The Society for Neuroscience
- Place of Presentation
  San Diego (アメリカ)
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05995
[Presentation] 不安障害再発モデルにおける前頭前皮質ドパミンの機能解明2016
- Author(s)
  人羅(今村)菜津子、三浦友樹、手代木知恵、池谷裕二、松木則夫、野村洋
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  ソウル (韓国)
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-15H05995
[Presentation] Prefrontal dopamine-dependent plasticity mediates relapse in an animal model of anxiety disorders2016
- Author(s)
  Natsuko Hitora-Imamura, Yuki Miura, Chie Teshirogi, Yuji Ikegaya, Norio Matsuki, Hiroshi Nomura
- Organizer
  The 30th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  ソウル (韓国)
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05995

1. Satoh Masamichi (80025709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 井手聡一郎 (30389118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 人羅勇気 (00755308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 福田隼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 周東智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hitora Natsuko 人羅 菜津子

HITORA Natsuko 人羅 菜津子

Research Projects

Research Products

Co-Researchers

可塑性を利用したうつ病予防法の開発に向けた、原因神経回路の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

葛藤下での行動選択のマルチセルラメカニズム解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

α-synucleinの分解促進・凝集阻害作用を示す天然物の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

異なる神経経路が行動を両方向に制御するメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating neural mechanisms to overcome fearPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

意志力を司る細胞集団メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating neural activity to improve treatment of anxiety disorders.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

正と負の意志の動的平衡を担う神経活動の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of resolvins and their mechanism of action on the sensory and emotional components of pain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of VTA-PFC circuit in an animal model of anxiety disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Evaluation of behavioural selection processes in conflict scenarios using a newly developed mouse behavioural paradigm2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Syrosingopine Enhances 20S Proteasome Activity and Degradation of α-Synuclein2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] M. Minami, Resolvin E1 and E2 ameliorate lipopolysaccharide-induced depression-like behaviors via ChemR232017

Author(s)

Journal Title

DOI

Data Source

Hitora Natsuko 人羅菜津子

HITORA Natsuko 人羅菜津子

[Presentation] 天然物からの 20S プロテアソーム活性化物質の探索と syrosingopine の作用に関する研究2023