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Hasegawa Emi  長谷川 恵美

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HASEGAWA Emi  長谷川 恵美

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Researcher Number 40765955
Other IDs
Affiliation (Current) 2025: 京都大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help 2025: 京都大学, 薬学研究科, 准教授
2022 – 2023: 京都大学, 薬学研究科, 准教授
2020 – 2022: 筑波大学, 医学医療系, 助教
2016 – 2020: 筑波大学, 国際統合睡眠医科学研究機構, 助教
Review Section/Research Field
Principal Investigator
Basic Section 48020:Physiology-related / Basic Section 46030:Function of nervous system-related / Environmental physiology(including physical medicine and nutritional physiology)
Except Principal Investigator
Basic Section 46020:Anatomy and histopathology of nervous system-related / Basic / Social brain science
Keywords
Principal Investigator
扁桃体 / ドーパミン / 睡眠 / マウス / レム睡眠 / 覚醒・睡眠 / マルチユニット記録 / 光遺伝学的手法 / ナルコレプシー / 報酬系 … More / 睡眠・覚醒 / in vivoレコーディングシステム / ファイバーフォトメトリー法 / カタプレキシー / オレキシン / 生理学 / 神経科学 / パッチクランプ法 / GABA受容体 / 電気生理学的特性 / 視交叉上核(SCN) / 中枢概日時計 … More
Except Principal Investigator
VMP / VTA / 化学遺伝学 / ドーパミン / マウス / 覚醒 / 腹側被蓋野 / GABA / 睡眠 / ヒスタミン / ノルアドレナリン / セロトニン / オレキシン / 錐体オプシン / 光遺伝学 / 睡眠・覚醒 Less
  • Research Projects

    (6 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (9 People)
  •  睡眠構造における加齢変容メカニズムの解明Principal Investigator

    • Principal Investigator
      長谷川 恵美
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Kyoto University
  •  REM睡眠開始における扁桃体基底外側核のドーパミンシグナルの役割の解明Principal Investigator

    • Principal Investigator
      長谷川 恵美
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Kyoto University
  •  The analysis of neural pathways in arousal maintenance and behavioral alteration under orexinPrincipal Investigator

    • Principal Investigator
      Hasegawa Emi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 46030:Function of nervous system-related
    • Research Institution
      University of Tsukuba
  •  Elucidation of sleep-regulatory mechanisms by the reward system

    • Principal Investigator
      Oishi Yo
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      University of Tsukuba
  •  The neurophysiological analysis of neuronal type selective in the circadian clockPrincipal Investigator

    • Principal Investigator
      HASEGAWA Emi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      University of Tsukuba
  •  Analysis of sleep-wake regulatory system by optogenetics featuring cone opsins.

    • Principal Investigator
      Maejima Takashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic / Social brain science
    • Research Institution
      Kanazawa University

All 2024 2023 2022 2019 2018 2017

All Journal Article Presentation Book

  • [Book] レム睡眠の開始機構-睡眠周期の生成に関するドーパミンと扁桃体の新たな役割2022

    • Author(s)
      長谷川恵美
    • Total Pages
      6
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Book] 睡眠/覚醒調節の謎に挑む:明らかになったレム睡眠の開始におけるドーパミンと扁桃体の役割2022

    • Author(s)
      櫻井武、長谷川恵美
    • Total Pages
      4
    • Publisher
      Neuro Logica
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Journal Article] Regulation of REM sleep in mice: The role of dopamine and serotonin function in the basolateral amygdala2024

    • Author(s)
      Hasegawa Emi、Li Yulong、Sakurai Takeshi
    • Journal Title

      Neuroscience Research

      Volume: 200 Pages: 28-33

    • DOI

      10.1016/j.neures.2023.09.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06826, KAKENHI-PLANNED-23H04941, KAKENHI-PROJECT-21H05036
  • [Journal Article] Connecting the amygdala and dopamine: exploring the mysteries of rapid-eye movement sleep2023

    • Author(s)
      Sakurai Takeshi、Hasegawa Emi
    • Journal Title

      SLEEP

      Volume: 46 Issue: 8

    • DOI

      10.1093/sleep/zsad157

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Journal Article] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2022

    • Author(s)
      Hasegawa Emi、Miyasaka Ai、Sakurai Katsuyasu、Cherasse Yoan、Li Yulong、Sakurai Takeshi
    • Journal Title

      Science

      Volume: 375 Issue: 6584 Pages: 994-1000

    • DOI

      10.1126/science.abl6618

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846, KAKENHI-PROJECT-22KJ0371, KAKENHI-PROJECT-22K06826, KAKENHI-PROJECT-21K19287, KAKENHI-PROJECT-21H05036
  • [Journal Article] Sleep and wakefulness are controlled by ventral medial midbrain/pons GABAergic neurons in mice2018

    • Author(s)
      Takata Y, Oishi Y, Zhou XZ, Hasegawa E, Takahashi K, Cherasse Y, Sakurai T, Lazarus M
    • Journal Title

      Journal of Neuroscience

      Volume: 0598-18 Issue: 47 Pages: 10080-10092

    • DOI

      10.1523/jneurosci.0598-18.2018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PROJECT-18H02534, KAKENHI-PUBLICLY-17H06047, KAKENHI-PROJECT-16K18698, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Serotonin neurons of the dorsal raphe mediate the anti-cataplectic action of orexin neurons by reducing the amygdala activity2017

    • Author(s)
      Hasegawa, E., Maejima, T., Yoshida, T., Masseck O.A., Herlitze, S., Yoshioka, M., Sakurai, T., Mieda, M.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 114 Issue: 17

    • DOI

      10.1073/pnas.1614552114

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-16H06400, KAKENHI-PLANNED-16H06401, KAKENHI-PROJECT-15K12768, KAKENHI-PUBLICLY-16H01608, KAKENHI-PROJECT-15H03122, KAKENHI-PROJECT-16H05120, KAKENHI-PROJECT-15K01832
  • [Presentation] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2023

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Katsuyasu Sakurai, Yoan Cherasse, Yulong Li, Takeshi Sakurai
    • Organizer
      第28回日本睡眠学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Presentation] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2023

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Katsuyasu Sakurai, Yoan Cherasse, Yulong Li, Takeshi Sakurai
    • Organizer
      The 11th Annual WPI-IIIS Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Presentation] 睡眠周期の生成に関与しているドーパミンと扁桃体の新たな役割の発見2023

    • Author(s)
      長谷川恵美、宮坂藍、ヨアンシェラス、櫻井勝康、李毓、櫻井武
    • Organizer
      日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会合同大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Presentation] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2023

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Katsuyasu Sakurai, Yoan Cherasse, Yulong Li, Takeshi Sakurai
    • Organizer
      Sleep2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Presentation] レム睡眠開始における扁桃体基底外側核のドーパミンシグナルの役割2022

    • Author(s)
      長谷川恵美、宮坂藍、Yoan Cherasse、櫻井勝康、Yulong Li、櫻井武
    • Organizer
      第45回日本神経科学大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Presentation] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2022

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Katsuyasu Sakurai, Yoan Cherasse, Yulong Li, Takeshi Sakurai,
    • Organizer
      WPI-IIIS/Fudan University Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2022

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Katsuyasu Sakurai, Yoan Cherasse, Yulong Li, Takeshi Sakurai
    • Organizer
      JST-CREST “Opt Bio” / WPI-IIIS Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice2022

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Katsuyasu Sakurai, Yoan Cherasse, Yulong Li, Takeshi Sakurai
    • Organizer
      JST-CREST “Opt Bio” / WPI-IIIS Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06826
  • [Presentation] レム睡眠関連脱力発作における扁桃体へのドーパミン放出の影響2019

    • Author(s)
      長谷川恵美、前島隆司、吉田隆行、柳沢正史、三枝理博、桜井武
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Neural circuits of cataplexy2019

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Takashi Maejima, Takayuki Yoshida, Katsuyasu Sakurai, Mitsuhiro Yoshioka, Masashi Yanagisawa, Michihiro Mieda, Takeshi Sakurai
    • Organizer
      World sleep 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Dopamine release into the amygdala might be involved in REM-related muscle atonia2019

    • Author(s)
      Emi Hasegawa, Ai Miyasaka, Takashi Maejima, Takayuki Yoshida, Katsuyasu Sakurai, Mitsuhiro Yoshioka, Masashi Yanagisawa, Michihiro Mieda, Takeshi Sakurai
    • Organizer
      World sleep 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] 扁桃体へのセロトニン神経入力はオレキシンを介して情動脱力発作の抑制する2018

    • Author(s)
      長谷川恵美、前島隆司、吉田隆行、Olivia Masseck、Stefan Horlitze、吉岡充弘、柳沢正史、三枝理博、櫻井武
    • Organizer
      日本睡眠学会 第43回 定期学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Search for neural circuits of narcolepsy-cataplexy2018

    • Author(s)
      Emi Hasegawa, Takashi Maejima, Takayuki Yoshida, Mitsuhiro Yoshioka, Masashi Yanagisawa, Michihiro Mieda, Takeshi Sakurai
    • Organizer
      Society for Neuroscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] ナルコレプシーの神経経路の探索2018

    • Author(s)
      長谷川恵美、前島隆司、三枝理博、櫻井武
    • Organizer
      日本睡眠学会 第43回 定期学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Neural circuits of narcolepsy2018

    • Author(s)
      Emi Hasegawa, Takashi Maejima, Takayuki Yoshida, Olivia A. Masseck, Stefan Herlitze, Mitsuhiro Yoshioka, Masashi Yanagisawa, Michihiro Mieda, Takeshi Sakurai
    • Organizer
      The 11thFENS Forum of Neuroscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14846
  • [Presentation] Neural circuits of narcolepsy2018

    • Author(s)
      Emi Hasegawa, Takashi Maejima, Takayuki Yoshida, Olivia A. Masseck, Stefan Herlitze, Mitsuhiro Yoshioka, Masashi Yanagisawa, Michihiro Mieda, Takeshi Sakurai
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K14846
  • 1.  Maejima Takashi (70399319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  SOYA Shingo (90791442)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  SAKURAI Takeshi (60251055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  MIEDA Michihiro (20296552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Oishi Yo (70554004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  シェラス ヨアン (60544319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  高田 陽子 (60435740)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Stefan Herlitze
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  桜井 武
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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