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Uchino Haruto  内野 晴登

ORCIDConnect your ORCID iD *help
Researcher Number 40775144
Other IDs
Affiliation (Current) 2025: 北海道大学, 大学病院, 特任助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 北海道大学, 大学病院, 特任助教
2021: 北海道大学, 医学研究院, 客員研究員
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related
Except Principal Investigator
Basic Section 56010:Neurosurgery-related
Keywords
Principal Investigator
DNAメチル化 / もやもや病
Except Principal Investigator
Moyamoya disease / microRNA / Epigenome / Pial synangiosis / 創始者変異 / RNF213 / エピゲノム / 血漿microRNA … More / 病態修飾因子 / 発症素因 / もやもや病 / pial synangiosis / angiogenesis / epigenome / blood biomarker / circulating microRNA Less
  • Research Projects

    (3 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (10 People)
  •  Epigenetic regulation analysis in angiogenesis/pial synangiosis on the meninges in Moyamoya disease

    • Principal Investigator
      伊東 雅基
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  もやもや病の末梢血細胞DNAメチル化解析による発病機序の解明Principal Investigator

    • Principal Investigator
      内野 晴登
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University
  •  Comprehensive validation of circulating microRNA signatures for Moyamoya disease early detection as an epigenome blood biomarker

    • Principal Investigator
      Ito Masaki
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Hokkaido University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Book

  • [Book] Epigenetics Methods, Chapter 23: Detection and Quantification of MicroRNAs (miRNAs) and High Throughput miRNAs Profiling2020

    • Author(s)
      Ito M, Uchino H
    • Total Pages
      736
    • Publisher
      Elsevier
    • ISBN
      9780128194140
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Impact of intraoperative cortical indocyanine green extravasation on local vasogenic edema immediately after direct revascularization in an adult with moyamoya disease: illustrative case2024

    • Author(s)
      YAMASAKI Maeho、ITO Masaki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
    • Journal Title

      Journal of Neurosurgery: Case Lessons

      Volume: 7 Issue: 13

    • DOI

      10.3171/case2465

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Efficacy of Mobile Telemedicine System for Digital Subtraction Angiography of Moyamoya Disease Compared with Picture Archiving and Communication System2024

    • Author(s)
      OSANAI Toshiya, UCHINO Haruto, ITO Masaki, FUJIMURA Miki
    • Journal Title

      JMA Journal

      Volume: 7 Issue: 2 Pages: 282-285

    • DOI

      10.31662/jmaj.2023-0129

    • ISSN
      2433-328X, 2433-3298
    • Year and Date
      2024-04-15
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Long-term Outcomes of Combined Revascularization Surgery for Moyamoya Disease in the Elderly: A Single Institute Experience2024

    • Author(s)
      KURISU Kota、ITO Masaki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
    • Journal Title

      Neurol. Med. Chir.(Tokyo)

      Volume: 64 Issue: 3 Pages: 108-115

    • DOI

      10.2176/jns-nmc.2023-0219

    • ISSN
      0470-8105, 1349-8029
    • Year and Date
      2024-03-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Predictive value of the hemispheric magnetic resonance angiography score on the development of indirect pial synangiosis after combined revascularization surgery for adult moyamoya disease2024

    • Author(s)
      UCHINO Haruto, ITO Masaki, FUJIMA Noriyuki, TOKAIRIN Kikutaro, TATEZAWA Ryota, SUGIYAMA Taku, FUJIMURA Miki
    • Journal Title

      Acta Neurochir (Wien)

      Volume: 166(1) Pages: 181-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Moyamoya Syndrome Associated with Late-onset Idiopathic Aqueduct Stenosis Successfully Treated with Endoscopic Third Ventriculostomy2024

    • Author(s)
      HONDA Taishi、ITO Masaki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
    • Journal Title

      NMC Case Report Journal

      Volume: 11 Issue: 0 Pages: 13-18

    • DOI

      10.2176/jns-nmc.2023-0195

    • ISSN
      2188-4226
    • Year and Date
      2024-12-31
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Effective Smartphone Application Use for Postoperative Management of Moyamoya Disease2024

    • Author(s)
      UCHINO Haruto, OSANAI Toshiya, ITO Masaki, KURISU Kota, SUGIYAMA Taku, FUJIMURA Miki
    • Journal Title

      Neurol Med Chir (Tokyo)

      Volume: 64(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability2023

    • Author(s)
      UCHINO Haruto、ITO Masaki、TOKAIRIN Kikutaro、TATEZAWA Ryota、SUGIYAMA Taku、KAZUMATA Ken、FUJIMURA Miki
    • Journal Title

      Neurosurgical Review

      Volume: 46 Issue: 1 Pages: 119-119

    • DOI

      10.1007/s10143-023-02030-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Chronological Volume Changes of the Temporal Muscle Pedicle Used for Encephalo-myo-synangiosis in Combined Revascularization for Moyamoya Disease: A Prospective Observational Study2023

    • Author(s)
      MIZUSHIMA Makoto、ITO Masaki、FUJIMA Noriyuki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
    • Journal Title

      Neurol. Med. Chir.(Tokyo)

      Volume: 63 Issue: 7 Pages: 304-312

    • DOI

      10.2176/jns-nmc.2023-0008

    • ISSN
      0470-8105, 1349-8029
    • Year and Date
      2023-07-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Impact of RNF213 founder polymorphism (p.R4810K) on the postoperative development of indirect pial synangiosis after direct/indirect combined revascularization surgery for adult Moyamoya disease2022

    • Author(s)
      Ito Masaki、Kawabori Masahito、Sugiyama Taku、Tokairin Kikutaro、Tatezawa Ryota、Uchino Haruto、Kazumata Ken、Houkin Kiyohiro、Fujimura Miki
    • Journal Title

      Neurosurgical Review

      Volume: online ahead of print Issue: 3 Pages: 2305-2313

    • DOI

      10.1007/s10143-022-01749-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765, KAKENHI-PROJECT-20K09362
  • [Journal Article] Crossed cerebellar diaschisis as an indicator of severe cerebral hyperperfusion after direct bypass for moyamoya disease2020

    • Author(s)
      Uchino Haruto、Kazumata Ken、Ito Masaki、Nakayama Naoki、Kuroda Satoshi、Houkin Kiyohiro
    • Journal Title

      Neurosurgical Review

      Volume: 44 Issue: 1 Pages: 599-605

    • DOI

      10.1007/s10143-020-01265-8

    • NAID

      120006958359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Optogenetic Stimulation Reduces Neuronal Nitric Oxide Synthase Expression After Stroke2020

    • Author(s)
      Pendharkar Arjun V.、Smerin Daniel、Gonzalez Lorenzo、Wang Eric H.、Levy Sabrina、Wang Stephanie、Ishizaka Shunsuke、Ito Masaki、Uchino Haruto、Chiang Terrance、Cheng Michelle Y.、Steinberg Gary K.
    • Journal Title

      Translational Stroke Research

      Volume: 12 Issue: 2 Pages: 347-356

    • DOI

      10.1007/s12975-020-00831-y

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Association of cognitive function with cerebral blood flow in children with moyamoya disease2020

    • Author(s)
      Kazumata Ken、Tokairin Kikutaro、Sugiyama Taku、Ito Masaki、Uchino Haruto、Osanai Toshiya、Kawabori Masahito、Nakayama Naoki、Houkin Kiyohiro
    • Journal Title

      Journal of Neurosurgery: Pediatrics

      Volume: 25 Issue: 1 Pages: 62-68

    • DOI

      10.3171/2019.7.peds19312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Journal Article] Brain Structure, Connectivity, and Cognitive Changes Following Revascularization Surgery in Adult Moyamoya Disease2019

    • Author(s)
      Kazumata Ken、Tha Khin Khin、Tokairin Kikutaro、Ito Masaki、Uchino Haruto、Kawabori Masahito、Sugiyama Taku
    • Journal Title

      Neurosurgery

      Volume: 85 Issue: 5 Pages: E943-E952

    • DOI

      10.1093/neuros/nyz176

    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] もやもや病のエピゲノム病態修飾因子<血漿microRNA>探索2024

    • Author(s)
      伊東雅基、内野晴登、東海林菊太郎、杉山拓、川堀真人、岩田育子、矢部一郎、寳金清博、藤村幹
    • Organizer
      第53回 日本脳卒中の外科学会学術集会 シンポジウム 02 (卒外SY02)
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] Incidence and characteristics of extremely advanced Moyamoya disease with Suzuki's angiographic stage 6: Single institute experience2023

    • Author(s)
      ITO Masaki, UCHINO Haruto, FUJIMURA Miki
    • Organizer
      International Symposium of Cerebral Blood Flow & Metabolism
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] Incidence and characteristics of extremely advanced Moyamoya disease with Suzuki's angiographic stage 6: Single institute experience2023

    • Author(s)
      ITO Masaki, UCHINO Haruto, FUJIMURA Miki
    • Organizer
      The 16th Korea-Japan Joint Conference on Surgery for Cerebral Stroke
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] もやもや病複合血行再建術後の側頭筋腫脹をもたらす患者要因の探索2023

    • Author(s)
      水嶋慎、伊東雅基、内野晴登、栗栖宏多、杉山拓、藤村幹
    • Organizer
      第53回 日本脳卒中の外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021

    • Author(s)
      伊東 雅基, 川堀 真人, 杉山 拓, 東海林 菊太郎, 舘澤 諒大, 内野 晴登, 数又 研, 寳金 清博, 藤村 幹
    • Organizer
      第80回日本脳神経外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] 成人もやもや病複合血行再建術後バイパス路発達度におけるRNF213創始者変異の意義2021

    • Author(s)
      伊東 雅基、川堀 真人、杉山 拓、東海林 菊太郎、舘澤 諒大、内野 晴登、数又 研、寳金 清博、藤村 幹
    • Organizer
      第39回 The Mt. Fuji workshop on CVD
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021

    • Author(s)
      伊東 雅基, 川堀 真人, 杉山 拓, 東海林 菊太郎, 舘澤 諒大, 内野 晴登, 数又 研, 寳金 清博, 藤村 幹
    • Organizer
      第64回 日本脳循環代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03765
  • [Presentation] 成人もやもや病に対する間接バイパス術に残された課題ーRNF213創始者変異術前検討の意義2021

    • Author(s)
      伊東 雅基, 川堀 真人, 杉山 拓, 東海林 菊太郎, 舘澤 諒大, 内野 晴登, 数又 研, 寳金 清博, 藤村 幹
    • Organizer
      第51回 日本脳卒中の外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03765
  • 1.  Ito Masaki (10399850)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 2.  藤村 幹 (00361098)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 3.  東海林 菊太郎 (70883164)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 4.  佐藤 典宏 (50360912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  矢部 一郎 (60372273)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  杉山 拓 (70748863)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 7.  寳金 清博 (90229146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 8.  中山 若樹 (40421961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  数又 研 (60634144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 10.  浜内 祝嗣 (70794387)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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