Tanioka Hiroaki 谷岡洋亮

Researcher Number	40775491
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 特任研究員
Affiliation (based on the past Project Information) *help	2023: 川崎医科大学, 医学部, 特任研究員 2019 – 2022: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 52010:General internal medicine-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 免疫療法 / メチル化 / エピゲノム / 薬物療法 / 免疫チェックポイント阻害剤 / バイオマーカー / 胃癌 Except Principal Investigator メチル化 / 脱メチル化 / 癌免疫 … More / 癌性腹膜炎 / 新規養子免疫細胞療法 / 脱メチル化剤 / 難治性癌性腹水 / サイトカイン / DNAメチル化 / せん妄 / 腫瘍検査学 / 大腸癌 / 腫瘍遺伝学 / 悪性腫瘍 / 逐次療法 / バイオマーカー / MGMT / オキサリプラチン / 逐次治療 / 化学療法 / 大腸がん Less

Construction of epigenetic biomarkers by regenerative indices of immune functionPrincipal Investigator
- Principal Investigator
  
  Tanioka Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kawasaki Medical School
Development of a new strategy to treat cancerous peritonitis
- Principal Investigator
  
  Nagasaka Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Medical School
Deep learningを用いたせん妄発症高リスク群予測モデルの構築
- Principal Investigator
  
  佐野史典
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki Medical School
Exploration of the Molecular Biological Characteristics of Advanced Colorectal Cancer Suitable for Sequential Therapy
- Principal Investigator
  
  Yamaguchi Yoshiyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kawasaki Medical School

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Genomically Stable Gastric Cancer Characterized by Hypomethylation in Wnt Signal Cascade2023
- Author(s)
  Toshima Toshiaki、Tanioka Hiroaki、Mori Yoshiko、Tanaka Takehiro、Yasui Kazuya、Kimura Keisuke、Umeda Yuzo、Fujiwara Toshiyoshi、Nyuya Akihiro、Yano Shuya、Nagasaka Takeshi
- Journal Title
  
  Oncology
  
  Volume: 101 Issue: 2 Pages: 105-116
- DOI
  10.1159/000527098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-21K16474, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-20K09110
[Journal Article] Neutrophil and lymphocyte ratio before each chemotherapy line predicts clinical outcomes in patients with unresectable gastric cancer.2023
- Author(s)
  Tanioka H, Okawaki M, Yano S, Yoshimitsu T, Tokuda K, Nyuya A, Yamaguchi Y, Nagasaka T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 25 Issue: 3 Pages: 98-98
- DOI
  10.3892/ol.2023.13684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16474, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-21K07185
[Journal Article] Phase 3 trial of sequential versus combination treatment in colorectal cancer: The C-cubed study2022
- Author(s)
  Ryo Inada, Takeshi Nagasaka, Mototsugu Shimokawa, Hitoshi Ojima, Shingo Noura, Hiroaki Tanioka, Yoshinori Munemoto, Yasuhiro Shimada, Keiichiro Ishibashi, Yoshiaki Shindo, Hideyuki Mishima, Masasumi Okajima, Yoshiyuki Yamaguchi
- Journal Title
  
  European Journal of Cancer
  
  Volume: 169 Pages: 166-178
- DOI
  10.1016/j.ejca.2022.04.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19934, KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-19K07787
[Journal Article] Phase II Study of S-1 and Irinotecan Plus Bevacizumab as Second-line Treatment for Patients With Metastatic Colorectal Cancer Resistant to the Fluoropyrimidine-oxaliplatin-cetuximab Regimen2022
- Author(s)
  TANIOKA HIROAKI、SHIMADA KEN、TSUJI AKIHITO、KOCHI MITSUGU、KIM HO MIN、TAKAHASHI TAKAO、DENDA TADAMICHI、TAKAGANE AKINORI、WATANABE TAKANORI、KOTAKA MASAHITO、NAKAMURA MASATO、SUNAKAWA YU、TAKEUCHI MASAHIRO、ICHIKAWA WATARU、FUJII MASASHI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 5 Pages: 2675-2681
- DOI
  10.21873/anticanres.15745
- Data Source
  KAKENHI-PROJECT-21K07185
[Journal Article] Impact of early tumor shrinkage on quality of life in patients treated with first-line cetuximab plus chemotherapy for unresectable metastatic colorectal cancer: results of Phase II QUACK trial2022
- Author(s)
  Ooki Akira、Morita Satoshi、Tsuji Akihito、Iwamoto Shigeyoshi、Hara Hiroki、Tanioka Hiroaki
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 711-723
- DOI
  10.1186/s12885-022-09811-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-17K10655
[Journal Article] Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations.2021
- Author(s)
  Kawai T, Nyuya A, Mori Y, Tanaka T, Tanioka H, Yasui K, Toshima T, Taniguchi F, Shigeyasu K, Umeda Y, Fujiwara T, Okawaki M, Yamaguchi Y, Goel A, Nagasaka T.
- Journal Title
  
  Clin Epigenetics.
  
  Volume: 13 (1) Issue: 1 Pages: 117-117
- DOI
  10.1186/s13148-021-01104-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-20K09110, KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-21K19934
[Journal Article] Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.2021
- Author(s)
  Taniguchi F, Nyuya A, Toshima T, Yasui K, Mori Y, Okawaki M, Kishimoto H, Umeda Y, Fujiwara T, Tanioka H, Yamaguchi Y, Goel A, Nagasaka T.
- Journal Title
  
  Future Sci OA.
  
  Volume: 7 (10) Issue: 10
- DOI
  10.2144/fsoa-2021-0059
- NAID
  120007170517
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-20K09110, KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-21K19934
[Journal Article] Safety and efficacy of panitumumab in combination with trifluridine/tipiracil for pre-treated patients with unresectable, metastatic colorectal cancer with wild-type RAS: The phase 1/2 APOLLON study2021
- Author(s)
  Kato Takeshi、Kagawa Yoshinori、Kuboki Yasutoshi、Gamoh Makio、Komatsu Yoshito、Yasui Hirofumi、Satake Hironaga、Oki Eiji、Tanioka Hiroaki、Kotaka Masahito、Makiyama Akitaka、Denda Tadamichi、Goto Masahiro、Yoshino Takayuki、Yamazaki Kentaro、Soeda Junpei、Shibuya Kazunori、Iwata Masaru、Oba Koji、Yamaguchi Kensei
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 7 Pages: 1238-1247
- DOI
  10.1007/s10147-021-01902-2
- Data Source
  KAKENHI-PROJECT-21K07185
[Journal Article] A phase II study of FOLFOXIRI plus bevacizumab as initial chemotherapy for patients with untreated metastatic colorectal cancer: TRICC1414 (BeTRI)2021
- Author(s)
  Shinozaki, K. Yamada, T. Nasu, J. Matsumoto, T. Yuasa, Y. Shiraishi, T. Nagano, H. Moriyama, I. Fujiwara, T. Miguchi, M. Yoshida, R. Nozaka, K. Tanioka, H. Nagasaka, T. Kurisu, Y. Kobayashi, M. Tsuchihashi, K. Inukai, M. Kikuchi, T. Nishina, T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 26 Issue: 2 Pages: 399-408
- DOI
  10.1007/s10147-020-01811-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787
[Journal Article] Hepatectomy Followed by Adjuvant Chemotherapy with 3-Month Capecitabine Plus Oxaliplatin for Colorectal Cancer Liver Metastases2021
- Author(s)
  Satake Hironaga、Hashida Hiroki、Tanioka Hiroaki、Miyake Yasuhiro、Yoshioka Shinichi、Watanabe Takanori、Matsuura Masato、Kyogoku Takahisa、Inukai Michio、Kotake Takeshi、Okita Yoshihiro、Matsumoto Toshihiko、Yasui Hisateru、Kotaka Masahito、Kato Takeshi、Kaihara Satoshi、Tsuji Akihito
- Journal Title
  
  The Oncologist
  
  Volume: 26 Issue: 7 Pages: e1125-e1132
- DOI
  10.1002/onco.13816
- Data Source
  KAKENHI-PROJECT-21K07185
[Journal Article] Adoptive immunotherapy for gastric cancer using zoledronate-activated killer cells: A prospective observational study2020
- Author(s)
  Yamaguchi, Y. Katata, Y. Sano, F. Tanioka, H. Okawaki, M. Yamamura, M. Nagasaka, T.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 13 Issue: 5 Pages: 55-55
- DOI
  10.3892/mco.2020.2125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787
[Journal Article] Upregulation of microRNA?31 is associated with poor prognosis in patients with advanced colorectal cancer2020
- Author(s)
  Kubota Nobuhito、Taniguchi Fumitaka、Nyuya Akihiro、Umeda Yuzo、Mori Yoshiko、Fujiwara Toshiyoshi、Tanioka Hiroaki、Tsuruta Atsushi、Yamaguchi Yoshiyuki、Nagasaka Takeshi
- Journal Title
  
  Oncology Letters
  
  Volume: 19（４） Pages: 2685-2694
- DOI
  10.3892/ol.2020.11365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-18K18464, KAKENHI-PROJECT-18H03554, KAKENHI-PROJECT-17K10634, KAKENHI-PROJECT-20K09110
[Presentation] Pre-treatment PD-1 lymphocyte ratio in blood may predict clinical outcome of gastric cancer patients under Nivolumab monotherapy2023
- Author(s)
  Hiroaki Tanioka, Takeshi Nagasaka, Shuya Yano, Makoto Okawaki, Masahiro Yamamura, Yoshiyuki Yamaguchi
- Organizer
  第20回日本臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-21K07185
[Presentation] Pre-treatment PD-1 lymphocyte ratio in blood may predict clinical outcome of gastric cancer patients under Nivolumab monotherapy2023
- Author(s)
  Hiroaki Tanioka, Takeshi Nagasaka, Shuya Yano, Makoto Okawaki, Masahiro Yamamura, Yoshiyuki Yamaguchi
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07185
[Presentation] Wnt signaling cascade における低メチル化を特徴とする Genomically stable 胃癌2022
- Author(s)
  谷岡洋亮, 安井和也, 母里淑子, 田中健大, 木村圭介, 入谷光洋, 岡脇誠, 矢野修也, 山口佳之, 永坂岳司
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] RAS/RAF/Microsatellite statusに間葉型を加えた新しいサブタイプによる大腸癌のPrecision Medicine2022
- Author(s)
  矢野修也, 重安邦俊, 谷岡洋亮, 山崎泰史, 河内麻里子, 平沢晃, 武田正, 香川俊輔, 藤原俊義, 永坂岳司
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19934
[Presentation] せん妄発症予測バイオマーカーの探索2022
- Author(s)
  岡脇誠, 永坂岳司, 谷岡洋亮, 矢野修也, 山口佳之
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] Wnt signaling cascadeにおける低メチル化を特徴とするGenomically stable 胃癌2022
- Author(s)
  谷岡洋亮, 安井和也, 母里淑子, 田中健大, 木村圭介, 入谷光洋, 岡脇誠, 矢野修也, 山口佳之, 永坂岳司
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07185
[Presentation] 胃癌ニボルマブ投与による末梢血 PD1CD8 陽性 T リンパ球変化は効果予測となりうる2021
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋佑, 岡脇誠, 山村真宏, 山口佳之
- Organizer
  第 59 回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] 胃癌ニボルマブ投与による末梢血 PD1CD8 陽性 T リンパ球変化は効果予測となりうる2021
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋佑, 岡脇誠, 山村真宏, 山口佳之
- Organizer
  第 59 回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19934
[Presentation] 胃癌薬物療法における投与前低好中球リンパ球比は良好な予後予測因子となりうる2021
- Author(s)
  谷岡洋亮、永坂岳司、堅田洋佑、佐野史典、岡脇誠、山村真弘、山口佳之
- Organizer
  第43回日本癌局所療法研究会
- Data Source
  KAKENHI-PROJECT-21K07185
[Presentation] 胃癌ニボルマブ投与による末梢血PD1CD8陽性Tリンパ球変化は効果予測となりうる2021
- Author(s)
  [演者] 谷岡洋亮:1 [共同演者] 永坂岳司:1, 堅田洋佑:1, 岡脇誠:1, 山村真宏:1, 山口佳之:1
- Organizer
  第59回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07185
[Presentation] Randomized phase III study of sequential treatment with capecitabine or 5-fluorouracil (FP) plus bevacizumab (BEV) followed by the addition with oxaliplatin (OX) versus initial combination with OX+FP+ BEV in the first-line chemotherapy for metastatic colorectal cancer: The C-cubed study2019
- Author(s)
  T. Nagasaka, R. Inada, H. Ojima, S. Noura, H. Tanioka, Y. Munemoto, Y. Shimada, K. Ishibashi, Y. Shindo, Y. Kagawa, A. Tomibayashi, K. Okamoto, A. Tsuji, Y. Tsuji, S. Yamaguchi, A. SAWAKI, H. Mishima, M. Shimokawa, M. Okajima, Y. Yamaguchi
- Organizer
  ESMO Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07787

1. Nagasaka Takeshi (30452569)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. 岡脇誠 (40509254)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. Yamaguchi Yoshiyuki (10230377)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. 堅田洋佑 (20716881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 佐野史典 (60435013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 矢野修也 (50794624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. UMEDA Yuzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 藤原俊義

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 重安邦俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanioka Hiroaki 谷岡 洋亮

Research Projects

Research Products

Co-Researchers

Construction of epigenetic biomarkers by regenerative indices of immune functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new strategy to treat cancerous peritonitis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deep learningを用いたせん妄発症高リスク群予測モデルの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of the Molecular Biological Characteristics of Advanced Colorectal Cancer Suitable for Sequential Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Genomically Stable Gastric Cancer Characterized by Hypomethylation in Wnt Signal Cascade2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neutrophil and lymphocyte ratio before each chemotherapy line predicts clinical outcomes in patients with unresectable gastric cancer.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase 3 trial of sequential versus combination treatment in colorectal cancer: The C-cubed study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase II Study of S-1 and Irinotecan Plus Bevacizumab as Second-line Treatment for Patients With Metastatic Colorectal Cancer Resistant to the Fluoropyrimidine-oxaliplatin-cetuximab Regimen2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of early tumor shrinkage on quality of life in patients treated with first-line cetuximab plus chemotherapy for unresectable metastatic colorectal cancer: results of Phase II QUACK trial2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Safety and efficacy of panitumumab in combination with trifluridine/tipiracil for pre-treated patients with unresectable, metastatic colorectal cancer with wild-type RAS: The phase 1/2 APOLLON study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A phase II study of FOLFOXIRI plus bevacizumab as initial chemotherapy for patients with untreated metastatic colorectal cancer: TRICC1414 (BeTRI)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatectomy Followed by Adjuvant Chemotherapy with 3-Month Capecitabine Plus Oxaliplatin for Colorectal Cancer Liver Metastases2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adoptive immunotherapy for gastric cancer using zoledronate-activated killer cells: A prospective observational study2020

Tanioka Hiroaki 谷岡洋亮