TODA Yuki 戸田侑紀

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Toda Yuki 戸田侑紀

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Researcher Number	40779724
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 京都薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator Extracellular vesicle / 乳酸アシドーシス / 好中球 / 肺 / pH / 細胞外小胞 / 前転移ニッチ / ミトコンドリア分画 / ALIX / tet-on … More / exosome分泌 / 細胞内シグナル伝達 / 細胞生存 / HK2発現制御 / 分泌制御シグナル / Exosome分泌 / 分泌制御機構 / ミトコンドリア / HK2 / Exosomes / 低酸素 / 核酸医薬の送達技術 / オートクライン / 多発性骨髄腫 / MLL白血病 / 細胞内移行 / 血液がん細胞 / リポソーム / 血液がん / siRNA / エクソソーム … More Except Principal Investigator エクソソーム / ドラッグデリバリーシステム / 急性リンパ芽球性白血病 / 造血器腫瘍 / 抗体薬物複合体 / 核酸医薬 / CD63 / エクソゾーム / 多発性骨髄腫 Less

Identification of factor to induce lactic acidosis in pre-metastatic nichePrincipal Investigator
- Principal Investigator
  
  戸田侑紀
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto Pharmaceutical University
Exosomal secretion of hypoxia-adapted multiple myeloma cellsPrincipal Investigator
- Principal Investigator
  
  Toda Yuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Pharmaceutical University
Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myeloma
- Principal Investigator
  
  Ashihara Eishi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Pharmaceutical University
Development of siRNA delivery for hematological malignancy using exosomal lipidPrincipal Investigator
- Principal Investigator
  
  Toda Yuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Pharmaceutical University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy2023
- Author(s)
  Matsui Toma、Toda Yuki、Sato Haruka、Itagaki Rina、Konishi Kazuya、Moshnikova Anna、Andreev Oleg A.、Hosogi Shigekuni、Reshetnyak Yana K.、Ashihara Eishi
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 13 Pages: 1258442-1258442
- DOI
  10.3389/fonc.2023.1258442
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06620
[Journal Article] 7,8-Dihydroxy-3-(4′-hydroxyphenyl)coumarin inhibits invasion and migration of osteosarcoma cells2023
- Author(s)
  Sugiyama Yuki、Nakamura Seikou、Tokuda Yuichi、Nakano Masakazu、Hattori Yasunao、Nishiguchi Hiroki、Toda Yuki、Hosogi Shigekuni、Yamashita Masayuki、Tashiro Kei、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 638 Pages: 200-209
- DOI
  10.1016/j.bbrc.2022.11.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06840, KAKENHI-PROJECT-21H02687, KAKENHI-PROJECT-20K07343, KAKENHI-PROJECT-20K17388
[Journal Article] POLD1 Is Required for Cell Cycle Progression by Overcoming DNA Damage in Malignant Pleural Mesothelioma2023
- Author(s)
  Shimizu Daiki、Ishibashi Miku、Yamada Tadaaki、Toda Yuki、Hosogi Shigekuni、Ashihara Eishi.
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 21 Issue: 2 Pages: 158-165
- DOI
  10.21873/cgp.20437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06620
[Journal Article] Hypoxia-adapted Multiple Myeloma Stem Cells Resist γδ-T-Cell-mediated Killing by Modulating the Mevalonate Pathway2023
- Author(s)
  Yusuke Sano、Naoko Kuwabara、Saori Nakagawa、Yuki Toda、Shigekuni Hosogi、Shinji Sato、Eishi Ashihara
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 2 Pages: 547-555
- DOI
  10.21873/anticanres.16191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17388
[Journal Article] Successful Incorporation of Exosome-Capturing Antibody-siRNA Complexes into Multiple Myeloma Cells and Suppression of Targeted mRNA Transcripts2022
- Author(s)
  Soma Emi、Yamayoshi Asako、Toda Yuki、Mishima Yuji、Hosogi Shigekuni、Ashihara Eishi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 3 Pages: 566-566
- DOI
  10.3390/cancers14030566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PLANNED-20H05874, KAKENHI-PROJECT-20K17388
[Journal Article] Expression level of BTN3A1 on the surface of CD14+ monocytes is a potential predictor of γδ T cell expansion efficiency2022
- Author(s)
  Tomogane Mako、Omura Maho、Sano Yusuke、Shimizu Daiki、Toda Yuki、Hosogi Shigekuni、Kimura Shinya、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 588 Pages: 47-54
- DOI
  10.1016/j.bbrc.2021.12.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388
[Journal Article] CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia2022
- Author(s)
  Imayoshi Natsuki、Yoshioka Makoto、Tanaka Kuniaki、Yang Shyh-Ming、Akahane Koshi、Toda Yuki、Hosogi Shigekuni、Inukai Takeshi、Okada Seiji、Maloney David J.、Nakahata Tatsutoshi、Takita Junko、Kato Itaru、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 49-54
- DOI
  10.1016/j.bbrc.2021.12.078
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-21K19405, KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-23K24298
[Journal Article] The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation2022
- Author(s)
  Amari Keigo、Sasagawa Satoru、Imayoshi Natsuki、Toda Yuki、Hosogi Shigekuni、Imamura Toshihiko、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 588 Pages: 147-153
- DOI
  10.1016/j.bbrc.2021.12.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20J22374, KAKENHI-PROJECT-20K17388
[Journal Article] A novel dipeptide type inhibitor of the Wnt/b-catenin pathway suppresses proliferation of acute myelogenous leukemia cells.2021
- Author(s)
  Ryosuke Wakabayashi, Yasunao Hattori, Shigekuni Hosogi, Yuki Toda, Kazuyuki Takata, Eishi Ashihara.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 535 Pages: 73-79
- DOI
  10.1016/j.bbrc.2020.12.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388
[Journal Article] Human Vγ9Vδ2?T cells exert anti-tumor activity independently of PD-L1 expression in tumor cells2021
- Author(s)
  Tomogane Mako、Sano Yusuke、Shimizu Daiki、Shimizu Teruki、Miyashita Masatsugu、Toda Yuki、Hosogi Shigekuni、Tanaka Yoshimasa、Kimura Shinya、Ashihara Eishi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 573 Pages: 132-139
- DOI
  10.1016/j.bbrc.2021.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-20K18123
[Journal Article] Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ2020
- Author(s)
  Kuroda E, Nishimura K, Kawanishi S, Sueyoshi M, Ueno F, Toji Y, Abo N, Konishi T, Harada K, Satake S, Shima C, Toda Y, Kitamura Y, Shimohama S, Ashihara E, Takata K.
- Journal Title
  
  Neuroscience
  
  Volume: 438 Pages: 217-228
- DOI
  10.1016/j.neuroscience.2020.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17388, KAKENHI-PROJECT-20H03569, KAKENHI-PROJECT-18K06904
[Journal Article] Peripheral blood-derived microglia-like cells decrease amyloid-β burden and ameliorate cognitive impairment in a mouse model of Alzheimer’s disease.2020
- Author(s)
  Kuroda E., Takata K., Nishimura K., Oka H., Sueyoshi M., Aitani M., Kouda A., Satake S., Shima C., Toda Y., Nakata S., Kitamura Y., and Ashihara E.
- Journal Title
  
  J. Alzheimers Dis.
  
  Volume: 73 (1) Issue: 1 Pages: 413-429
- DOI
  10.3233/jad-190974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06904, KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-19J15414
[Journal Article] Factors Associated with Dose Modification of Lenalidomide Plus Dexamethasone Therapy in Multiple Myeloma2020
- Author(s)
  Yoko Kado, Masayuki Tsujimoto, Shin-ichi Fuchida, Akira Okano, Mayumi Hatsuse, Satoshi Murakami, Hikofumi Sugii, Kumi Ueda, Yuki Toda, Tetsuya Minegaki, Kohshi Nishiguchi, Yuichi Muraki, Chihiro Shimazaki, Eishi Ashihara.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 8 Pages: 1253-1258
- DOI
  10.1248/bpb.b20-00337
- NAID
  130007883792
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20K17388
[Journal Article] 6-Hydroxythiobinupharidine Inhibits Migration of LM8 Osteosarcoma Cells by Decreasing Expression of LIM Domain Kinase 1.2019
- Author(s)
  Yoshizawa M, Nakamura S, Sugiyama Y, Tamai S, Ishida Y, Sueyoshi M, Toda Y, Hosogi S, Yano Y, Ashihara E.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Issue: 12 Pages: 6507-6513
- DOI
  10.21873/anticanres.13865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826
[Journal Article] DJ-1 Contributes to Self-renewal of Stem Cells in the U87-MG Glioblastoma Cell Line.2019
- Author(s)
  Toda Y, Yoshimura R, Itahara M, Imai Y, Yamada K, Uno T, Nakata S, Hosogi S, Takata K, Ashihara E.
- Journal Title
  
  Anticancer Res.
  
  Volume: 39 Issue: 11 Pages: 5983-5990
- DOI
  10.21873/anticanres.13803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826
[Journal Article] Multiple myeloma cells adapted to long-exposure of hypoxia exhibit stem cell characters with TGF-β/Smad pathway activation2018
- Author(s)
  Nakagawa Yoko、Ashihara Eishi、Yao Hisayuki、Yokota Asumi、Toda Yuki、Miura Yasuo、Nakata Susumu、Hirai Hideyo、Maekawa Taira
- Journal Title
  
  BBRC
  
  Volume: 496 Issue: 2 Pages: 490-496
- DOI
  10.1016/j.bbrc.2018.01.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07171, KAKENHI-PROJECT-16K08722, KAKENHI-PROJECT-17K16197
[Presentation] 転移予定臓器におけるpH環境の変化-転移リスクマネジメントの発展を目指して-2024
- Author(s)
  戸田侑紀松井透磨, 細木誠之, 芦原英司
- Organizer
  2024 年がん関連三学会 Rising Star ネットワーキング
- Data Source
  KAKENHI-PROJECT-23K06620
[Presentation] 転移予定臓器における組織酸性化の転移巣形成への寄与2023
- Author(s)
  小西和也, 松井透磨, 戸田侑紀, 細木誠之, 芦原英司
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] 4T1.2より分泌される細胞外小胞は糖代謝リプログラミングにより肺組織酸性化を誘導する2023
- Author(s)
  佐藤晴夏, 松井透磨, 戸田侑紀, Anna Mosnikova, Oleg A. Andreev, 細木誠之, Yana K. Reshetnyak, 芦原英司
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06620
[Presentation] pH-low insertion peptideを用いた転移予定臓器における組織酸性化の検出2022
- Author(s)
  松井透磨, 戸田侑紀, 中井亮太, 横川碧, 板垣里奈, 細木誠之, 芦原英司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] pH-low insertion peptide detects lactic acidosis contributing metastatic niche formation in lungs2022
- Author(s)
  Toma Matsui, Yuki Toda, Anna Mosnikova, Oleg A. Andreev, Shigekuni Hosogi, Yana K. Reshetnyak, Eishi Ashihara
- Organizer
  American Association for Cancer Research Special Conference: CANCER METASTASIS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] pH-low insertion peptide accumulated in lung metastatic niche with lactic acidosis2022
- Author(s)
  Toma Matsui, Yuki Toda, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] pH-low insertion peptideで捉える転移予定臓器における組織pHの変化2022
- Author(s)
  戸田侑紀, 松井透磨, 細木誠之, 芦原英司
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] pH-low insertion peptideを用いた転移予定臓器における組織酸性化の検出2022
- Author(s)
  松井透磨、戸田侑紀、中井亮太、横川碧、板垣里奈、細木誠之、芦原英司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] Detection of acidic environment in metastatic niche by pH-low insertion peptide2022
- Author(s)
  Toma Matsui、Yuki Toda、Eiko Sawada、Aoi Yokogawa、Ryota Nakai、Rina Itagaki、Anna Mosnikova、Oleg A. Andreev、Shigekuni Hosogi、Yana K. Reshetnyak、Eishi Ashihara
- Organizer
  The 5th International Cancer Research Symposium - a Training for Oncology Professionals
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] A novel coumarin-based compound inhibits invasion and migration of osteosarcoma cells2021
- Author(s)
  Yuki Sugiyama, Seikou Nakamura, Kimika Yamaguchi, Yasunao Hattori, Yuki Toda, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] UCHL5 overexpression confers resistance to BETi in MLL-r leukemia cells by suppressing degradation of BRD4 protein2021
- Author(s)
  Keigo Amari、Yuki Toda、Shigekuni Hosogi、Toshihiko Imamura、Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] Butyrophilin3A1のγδT細胞の増幅効率の予測マーカーとしての有用性.2021
- Author(s)
  大村真穂, 友金眞光, 戸田侑紀, 細木誠之, 芦原英司,
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] UCHL5 overexpression confers resistance to BETi in MLL-r leukemia cells by suppressing degradation of BRD4 protein.2021
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura and Eishi Ashihara.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] A novel dipeptide type Wnt/β-catenin pathway inhibitor suppresses proliferation of acute myelogenous leukemia cells2021
- Author(s)
  Yuki Hadate, Ryosuke Wakabayashi, Yasunao Hattori, ShigekuniHosogi, Yuki Toda, Kazuyuki Takata, Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] A novel coumarin-based compound inhibits invasion and migration of osteosarcoma cells2021
- Author(s)
  Yuki Sugiyama、Seikou Nakamura、Kimika Yamaguchi、Yasunao Hattori、Yuki Toda、Shigekuni Hosogi、Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] A novel dipeptide type Wnt/β-catenin pathway inhibitor suppresses proliferation of acute myelogenous leukemia cells2021
- Author(s)
  Yuki Hadate、Ryosuke Wakabayashi、Yasunao Hattori、Shigekuni Hosogi、Yuki Toda、Kazuyuki Takata、Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] Acidic microenvironment increased the anti-tumor effect of γδT cell on A549 lung cancer cells2021
- Author(s)
  Shura Yarimizu、Shigekuni Hosogi、Mina Suzuki、Nobuhisa Tohdo、Daiki Shimizu、Yusuke Sano、Natsuki Imayoshi、Keigo Amari、Makou Tomogane、Yuki Toda、Eishi Ashihara
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] Application of BET/CBP/p300 multi-bromodomain inhibitors as a novel therapeutic strategy for MLL-rearranged acute lymphoblastic leukemia.2020
- Author(s)
  Natsuki Imayoshi, Makoto Yoshioka, Shyh-Ming Yang, Koshi Akahane, Yuki Toda, Shigekuni Hosogi, Takeshi Inukai, Seiji Okada, David J. Maloney, Jeffrey W. Strovel, Eishi Ashihara.
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2020
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] ovel BET/CBP/p300 multi-bromodomain inhibitors as a strategy for MLL-rearranged ALL.2020
- Author(s)
  Natsuki Imayoshi, Makoto Yoshioka, Kuniaki Tanaka, Shyh-Ming Yang, Koshi Akahane, Yuki Toda, Shigekuni Hosogi, Takeshi Inukai, Seiji Okada, David J. Maloney, Itaru Kato, Eishi Ashihara.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 低酸素環境に適応した多発性骨髄腫に対するγδT細胞の抗腫瘍効果.2020
- Author(s)
  佐野友亮、友金眞光、清水大器、宮下雅亜、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Cdk4/6i Abemaciclib overcomes resistance to BETi in leukemic cells with MLL-AF5q31 fusion gene2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] γδT細胞の体外増幅培養における予測可能なバイオマーカーの探索.2020
- Author(s)
  金眞光、宮下雅亜、佐野友亮、清水大器、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 低酸素環境に適応した多発性骨髄腫に対するγδT細胞の抗腫瘍効果2020
- Author(s)
  佐野友亮, 友金眞光, 清水大器, 宮下雅亜, 戸田侑紀, 細木誠之, 芦原英司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] 急性骨髄性白血病に対する新規ペプチド型Wnt/β-catenin阻害剤の効果2020
- Author(s)
  若林亮介, 服部恭尚, 戸田侑紀, 細木誠之, 芦原英司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] Anti-tumor effects of a novel Wnt/β-catenin pathway inhibitor against acute myelogenous leukemia.2020
- Author(s)
  Ryosuke Wakabayashi, Yasunao Hattori, Yusuke Sano, Yuki Sugiyama, Natsuki Imayoshi, Makou Tomogane, Keigo Amari, Yuki Toda,　Kazuya Kobayashi, Shigekuni Hosogi, Kenichi Akaji, Eishi Ashihara.
- Organizer
  The 3rd International Cancer Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Leukemic cells with MLL-AF5q31 fusion acquire BET inhibitor resistance by upregulation Bcl-2 expression.2020
- Author(s)
  Keigo Amari, Natsuki Imayoshi, Yusuke Sano, Yuki Sugiyama, Makou Tomogane, Ryosuke Wakabayashi, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura Eishi Ashihara.
- Organizer
  The 3rd International Cancer Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Cdk4/6 inhibitor Abemaciclib overcomes resistance to BET inhibitor in leukemic cells with MLL-AF5q31 fusion gene.2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara.
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2020
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Cdk4/6 inhibitor Abemaciclib overcomes resistance to BET inhibitor in leukemic cells with MLL-AF5q31 fusion gene2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara.
- Organizer
  American Association for Cancer Research Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] γδT細胞の体外増幅培養における予測可能なバイオマーカーの探索2020
- Author(s)
  友金眞光, 宮下雅亜, 佐野友亮, 清水大器, 戸田侑紀, 細木誠之, 芦原英司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] 骨髄系細胞が動員された前転移ニッチにおける乳酸アシドーシス2020
- Author(s)
  松井透磨, 戸田侑紀, 細木誠之, 芦原英司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] 骨髄系細胞が動員された前転移ニッチにおける乳酸アシドーシス.2020
- Author(s)
  松井透磨、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 急性骨髄性白血病に対する新規ペプチド型Wnt/β-catenin阻害剤の効果.2020
- Author(s)
  若林亮介、服部恭尚、戸田侑紀、細木誠之、芦原英司.
- Organizer
  第79回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Cdk4/6i Abemaciclib overcomes resistance to BETi in leukemic cells with MLL-AF5q31 fusion gene2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara..
- Organizer
  第82回日本血液学会学術集会.
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Application of BET/CBP/p300 multi-bromodomain inhibitors as a novel therapeutic strategy for MLL-rearranged acute lymphoblastic leukemia2020
- Author(s)
  Natsuki Imayoshi, Makoto Yoshioka, Shyh-Ming Yang, Koshi Akahane, Yuki Toda, Shigekuni Hosogi, Takeshi Inukai, Seiji Okada, David J. Maloney, Jeffrey W. Strovel, Eishi Ashihara.
- Organizer
  American Association for Cancer Research Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] Novel BET/CBP/p300 multi-bromodomain inhibitors as a strategy for MLL-rearranged ALL2020
- Author(s)
  Natsuki Imayoshi, Makoto Yoshioka, Kuniaki Tanaka, Shyh-Ming Yang, Koshi Akahane, Yuki Toda, Shigekuni Hosogi, Takeshi Inukai, Seiji Okada, David J. Maloney, Itaru Kato, Eishi Ashihara.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] MLL-AF5q31 cells acquire BET inhibitor resistance by Brd4-regulated molecules upregulation2020
- Author(s)
  Keigo Amari, Yuki Toda, Shigekuni Hosogi, Toshihiko Imamura, Eishi Ashihara.
- Organizer
  Global Academic Programs 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17388
[Presentation] 急性骨髄性白血病に対するWnt/β-catenin経路阻害効果を有する新規抗がん剤の抗腫瘍効果.2020
- Author(s)
  若林亮介、服部恭尚、羽立祐貴、戸田侑紀、細木誠之、赤路健一、芦原英司.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] 骨髄系細胞が動員された前転移ニッチにおける乳酸アシドーシス.2020
- Author(s)
  松井透磨、戸田侑紀、沢田瑛子、浅山菜々子、板原多勇、中井亮太、横川碧、細木誠之、芦原英司.
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Development of exosome-capturing antibody-conjugated nucleic acid medicines targeting multiple myeloma cells.2019
- Author(s)
  Emi Soma, Yuki Toda, Shigekuni Hosogi, Asako Yamayoshi, Eishi Ashihara
- Organizer
  The 61st Annual Meeting of the American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Coumarin-based compounds inhibit migration and invasion of murine osteosarcoma LM-8 cells.2019
- Author(s)
  杉山雄輝、山下正行、中村誠宏、長谷川功紀、西口大生、笠原愛実、吉澤正人、戸田侑紀、細木誠之、芦原英司
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Exosomal lipids applicable to cancer targeting.2019
- Author(s)
  Yuki Toda, Saeka Ukai, Akari Kobayashi, Shin-ya Morita, Eishi Ashihara
- Organizer
  The 8th Congress of the International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Increased exosome secretion is essential for myeloma stem cells to survive in hypoxic condition.2019
- Author(s)
  Sayaka Nakayama, Yuki Toda, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  The 8th Congress of the International Society for Extracellular Vesicles
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] Increased exosome secretion is a way of hypoxic adaptation in multiple myeloma cells.2019
- Author(s)
  Yuki Toda, Sayaka Nakayama, Shigekuni Hosogi, Eishi Ashihara
- Organizer
  The 44th Annual Meeting of the Japanese Society of Myeloma
- Data Source
  KAKENHI-PROJECT-19K08826
[Presentation] The role of DJ-1 in cancer stem cells2018
- Author(s)
  Yuki Toda
- Organizer
  京都 Cancer Biology セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] 神経膠芽種幹細胞におけるDJ-1の機能2018
- Author(s)
  戸田侑紀、吉村亮介、板原多勇、宇野智子、中田晋、山田佳菜枝、今井悠莉、高田和幸、芦原英司
- Organizer
  生体機能と創薬シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] Exosomesの指向性を利用した薬物送達技術の開発2018
- Author(s)
  戸田侑紀
- Organizer
  第23回大文字クラブ
- Invited
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] DJ-1 regulates stem cell function in glioblastoma2018
- Author(s)
  Yuki Toda, Masao Itahara, Eishi Ashihara
- Organizer
  The 77th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] DJ-1は神経膠芽種幹細胞の維持に寄与する2018
- Author(s)
  戸田侑紀、吉村亮介、板原多勇、宇野智子、中田晋、山田佳菜枝、今井悠莉、高田和幸、芦原英司
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] Cancer targeting using exosomal lipids toward detection enhancement of microlesion2018
- Author(s)
  Yuki Toda, Hikaru Kawakami, Saeka Ukai, Shin-ya Morita, Kazuyuki Takata, Eishi Ashihara
- Organizer
  3rd AACR-SNMMI Joint Conference on State-of-the-Art Molecular Imaging in Cancer Biology and Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] 生体内の情報伝達顆粒を利用した腫瘍標的化技術の開発2018
- Author(s)
  戸田侑紀
- Organizer
  KYOTO BASIC SCIENCE FORUM
- Invited
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] エクソソーム膜脂質より再構成したリポソームのがん細胞移行性評価2017
- Author(s)
  鵜飼幸永佳、戸田侑紀、川上光、高田和幸、芦原英司
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] 細胞外小胞の脂質組成から見出した新規がん標的型DDS2017
- Author(s)
  戸田侑紀、芦原英司
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16197
[Presentation] 細胞指向性を制御するエクソソームの脂質と薬物送達への応用2017
- Author(s)
  戸田侑紀、川上光、鵜飼幸永佳、森田真也、高田和幸、芦原英司
- Organizer
  第11回次世代を担う若手医療薬科学シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K16197

1. Ashihara Eishi (70275197)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
2. 河嶋秀和 (70359438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Morita Shin-ya

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. NAKANO Masakazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 北村佳久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 徳田雄市

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 田代啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 笹川覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 前川平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 平位秀世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TODA Yuki 戸田 侑紀

Toda Yuki 戸田 侑紀

Research Projects

Research Products

Co-Researchers

Identification of factor to induce lactic acidosis in pre-metastatic nichePrincipal Investigator

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Exosomal secretion of hypoxia-adapted multiple myeloma cellsPrincipal Investigator

Principal Investigator

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Research Institution

Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myeloma

Principal Investigator

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Review Section

Research Institution

Development of siRNA delivery for hematological malignancy using exosomal lipidPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy2023

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[Journal Article] 7,8-Dihydroxy-3-(4′-hydroxyphenyl)coumarin inhibits invasion and migration of osteosarcoma cells2023

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[Journal Article] POLD1 Is Required for Cell Cycle Progression by Overcoming DNA Damage in Malignant Pleural Mesothelioma2023

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[Journal Article] Hypoxia-adapted Multiple Myeloma Stem Cells Resist γδ-T-Cell-mediated Killing by Modulating the Mevalonate Pathway2023

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[Journal Article] Successful Incorporation of Exosome-Capturing Antibody-siRNA Complexes into Multiple Myeloma Cells and Suppression of Targeted mRNA Transcripts2022

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[Journal Article] Expression level of BTN3A1 on the surface of CD14+ monocytes is a potential predictor of γδ T cell expansion efficiency2022

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[Journal Article] CN470 is a BET/CBP/p300 multi-bromodomain inhibitor and has an anti-tumor activity against MLL-rearranged acute lymphoblastic leukemia2022

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[Journal Article] The CDK4/6-UCHL5-BRD4 axis confers resistance to BET inhibitors in MLL-rearranged leukemia cells by suppressing BRD4 protein degradation2022

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[Journal Article] A novel dipeptide type inhibitor of the Wnt/b-catenin pathway suppresses proliferation of acute myelogenous leukemia cells.2021

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[Journal Article] Human Vγ9Vδ2?T cells exert anti-tumor activity independently of PD-L1 expression in tumor cells2021

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[Journal Article] Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ2020

TODA Yuki 戸田侑紀

Toda Yuki 戸田侑紀