. . 岩崎広高

… Alternative Names

岩崎広高イワサキヒロタカ

Iwasaki Hirotaka 岩崎広高

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Researcher Number	40781589
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 客員助教
Affiliation (based on the past Project Information) *help	2022: 滋賀医科大学, 医学部, 助教 2018 – 2020: 滋賀医科大学, 医学部, 助教 2017: 滋賀医科大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Metabolomics Except Principal Investigator Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator ペプチダーゼ / 脂質ナノ粒子 / FGF21 / 熱産生 / 褐色脂肪組織 / ナルディライジン / 肝細胞 / microRNA / iPS細胞 / 骨格筋分化 … More / 2a型筋線維 / p300 / ヒトiPS細胞 / miR-494 / 運動 / miRNA / 筋分化 / 骨格筋 … More Except Principal Investigator ナルディライジン / ペプチダーゼ / 抗体産生 / エネルギー代謝 / 恒常性 Less

Investigation of the mechanisms by which Multifaceted Homeostasis is maintained by Nardilysin
- Principal Investigator
  
  Nishi Eiichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Shiga University of Medical Science
Development of novel therapeutic drug for obesity targeting liver multifunctional peptidasePrincipal Investigator
- Principal Investigator
  
  岩崎広高
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Shiga University of Medical Science
Investigation of skeletal muscle atrophy mechanism and role of microRNA using human iPS cellsPrincipal Investigator
- Principal Investigator
  
  Iwasaki Hirotaka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science

All 2022 2021 2020 2018

All Journal Article Presentation

[Journal Article] Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis2022
- Author(s)
  Saijo S, Ohno M, Iwasaki H, Matsuda S, Nishi K, Hiraoka Y, Ide N, Kimura T, Nishi E.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 3449-3449
- DOI
  10.1038/s41598-022-07379-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05958, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-21K20867, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22H04922
[Journal Article] Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine2022
- Author(s)
  Nishimura Kimihiro、Fujita Yukihiro、Ida Shogo、Yanagimachi Tsuyoshi、Ohashi Natsuko、Nishi Kiyoto、Nishida Atsushi、Iwasaki Yasumasa、Morino Katsutaro、Ugi Satoshi、Nishi Eiichiro、Andoh Akira、Maegawa Hiroshi
- Journal Title
  
  Molecular Metabolism
  
  Volume: 59 Pages: 101458-101458
- DOI
  10.1016/j.molmet.2022.101458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08998, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-18H02862, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-21K20867
[Journal Article] MicroRNA-494-3p inhibits formation of fast oxidative muscle fibres by targeting E1A-binding protein p300 in human-induced pluripotent stem cells2021
- Author(s)
  Iwasaki Hirotaka、Ichihara Yoshinori、Morino Katsutaro、Lemecha Mengistu、Sugawara Lucia、Sawano Tatsuya、Miake Junichiro、Sakurai Hidetoshi、Nishi Eiichiro、Maegawa Hiroshi、Imamura Takeshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1161-1161
- DOI
  10.1038/s41598-020-80742-y
- NAID
  120006953800
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09020, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-19K20182, KAKENHI-PROJECT-19H03378, KAKENHI-PROJECT-20H03449
[Journal Article] Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels2021
- Author(s)
  Yasuda Daisuke、Hiraoka Yoshinori、Ohno Mikiko、Nishi Kiyoto、Iwasaki Hirotaka、Kita Toru、Nishi Eiichiro、Kume Noriaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 3 Pages: 363-371
- DOI
  10.1248/bpb.b20-00722
- NAID
  130007993442
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-20K08445
[Journal Article] Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels2021
- Author(s)
  Daisuke Yasuda, Yoshinori Hiraoka, Mikiko Ohno, Kiyoto Nishi, Hirotaka Iwasaki, Toru Kita, Eiichiro Nishi, Noriaki Kume
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Pages: 363-371
- NAID
  130007993442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16130
[Journal Article] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and Nishi E
- Journal Title
  
  FASEB Journal
  
  Volume: 34 Issue: 9 Pages: 11624-11640
- DOI
  10.1096/fj.202000604r
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06280
[Presentation] Nardilysin in hepatocyte regulates diet-induced thermogenesis via the modulation of brown adipose tissue activity2022
- Author(s)
  Kiyoto Nishi、Hirotaka Iwasaki、Mikiko Ohno、Shintaro Matsuda、Eiichiro Nishi
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 多機能プロテアーゼによる心拍数制御機構2021
- Author(s)
  大野美紀子, 松浦博, 牧山武, 糀谷泰彦, 西清人, 岩崎広高, 松田真太郎, 木村剛, 西英一郎
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2021
- Author(s)
  Ohno M, Matsuura H, Makiyama T, Nishi K, Iwasaki T, Matsuda S, Kita T, Kimura T, and Nishi E
- Organizer
  第31回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する2021
- Author(s)
  西清人, 岩崎広高, 松田真太郎, 松田真太郎, 大野美紀子, 西英一郎
- Organizer
  第53回日本動脈硬化学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and Nishi E
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor2020
- Author(s)
  Ohno M, Nishi K, Hiraoka Y, Niizuma S, Matsuda S, Iwasaki H, Kimura K, and Nishi E
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2020
- Author(s)
  Ohno M, Matsuura H., Makiyama T., Nishi K., Iwasaki H., Matsuda S., Kita T., Kimura T., and Nishi E.
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] ナルディライジンはp75NTRの調節を介して心臓交感神経分布パターンを調節する2020
- Author(s)
  大野美紀子、西　清人、平岡　義範、新妻　晋一朗、岩崎　広高、松田　真太郎、木村　剛、西　英一郎
- Organizer
  第30回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20H03449
[Presentation] MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis by targeting transcriptional coactivator p300 in human induced pluripotent stem cells.2018
- Author(s)
  Hirotaka Iwasaki
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17814
[Presentation] MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis by targeting transcriptional coactivator p300 in human induced pluripotent stem cells.2018
- Author(s)
  Iwasaki H, Morino K, Ohno M, Sakurai H, Maegawa H, Nishi E, Imamura T
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17814

1. Nishi Eiichiro (30362528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. 大野美紀子 (10583198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. MORINO Katsutaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 平岡義範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 卯木智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

. . 岩崎 広高

岩崎 広高 イワサキ ヒロタカ

Iwasaki Hirotaka 岩崎 広高

Research Projects

Research Products

Co-Researchers

Investigation of the mechanisms by which Multifaceted Homeostasis is maintained by Nardilysin

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutic drug for obesity targeting liver multifunctional peptidasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of skeletal muscle atrophy mechanism and role of microRNA using human iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-494-3p inhibits formation of fast oxidative muscle fibres by targeting E1A-binding protein p300 in human-induced pluripotent stem cells2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Deficiency of Nardilysin in the Liver Reduces Serum Cholesterol Levels2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Nardilysin in hepatocyte regulates diet-induced thermogenesis via the modulation of brown adipose tissue activity2022

Author(s)

Organizer

Data Source

[Presentation] 多機能プロテアーゼによる心拍数制御機構2021

Author(s)

Organizer

Data Source

[Presentation] Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity2021

Author(s)

Organizer

Data Source

[Presentation] 肝細胞のナルディライジンは褐色脂肪組織の熱産生を制御する2021

Author(s)

Organizer

Data Source

[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor.2020

Author(s)

Organizer

Data Source

[Presentation] Nardilysin controls cardiac sympathetic innervation patterning through regulation of p75 neurotrophin receptor2020

. . 岩崎広高

岩崎広高イワサキヒロタカ

Iwasaki Hirotaka 岩崎広高