Keleku-Lukwete Nadine Keleku Nadine

Researcher Number	40781761
Affiliation (based on the past Project Information) *help	2017: 東北大学, 医学系研究科, 助教 2016: 東北大学, 医学系研究科, 産学官連携研究員
Review Section/Research Field	Principal Investigator Pathological medical chemistry
Keywords	Principal Investigator oxidative stress / Specific activation / Oxidative stress / Nrf2 activation / Sickle cell disease / endothelial cells / Myeloid cells / Keap1 knockout / Nrf2 / sickle cell disease

Development of a novel therapy for sickle cell disease by Nrf2 activationPrincipal Investigator
- Principal Investigator
  
  Keleku-Lukwete Nadine
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University

All 2018 2017 2016

All Journal Article Presentation

[Journal Article] An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment2018
- Author(s)
  Keleku-Lukwete Nadine、Suzuki Mikiko、Yamamoto Masayuki
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: - Issue: 17 Pages: 1746-1755
- DOI
  10.1089/ars.2017.7358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H06639
[Journal Article] Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.2017
- Author(s)
  Tsuchida K, Tsujita T, Hayashi M, Ojima A, Keleku-Lukwete N, Katsuoka F, Otsuki A, Kikuchi H, Oshima Y, Suzuki M, Yamamoto M.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 103 Pages: 236-247
- DOI
  10.1016/j.freeradbiomed.2016.12.041
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-16H06639, KAKENHI-PROJECT-16H07149, KAKENHI-PROJECT-26461395
[Journal Article] Overview of redox regulation by Keap1-Nrf2 system in toxicology and cancer.2016
- Author(s)
  Suzuki M, Otsuki A, Keleku-Lukwete N, Yamamoto M.
- Journal Title
  
  Curr Opin in Toxicol
  
  Volume: 1 Pages: 29-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06639
[Presentation] Nrf2 induction by oral administration of glucoraphanin relieves tissue damage in sickle cell disease.2017
- Author(s)
  Harit Panda、Nadine Keleku-Lukwete、Mikiko Suzuki、Masayuki Yamamoto.
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H06639
[Presentation] Sulforaphane relives inflammation and organ damage in sickle cell disease by inducing Nrf2.2017
- Author(s)
  Harit Panda, Nadine Keleku-Lukwete, Mikiko Suzuki, Masayuki Yamamoto.
- Organizer
  日本生化学会東北支部第83回例会
- Data Source
  KAKENHI-PROJECT-16H06639
[Presentation] Insight mechanism underlying the importance of Nrf2 in sickle cell disease.2016
- Author(s)
  Nadine Keleku-Lukwete、Harit Panda、長沼絵里子、鈴木未来子、山本雅之.
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター, 仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H06639

1. SUZUKI Norio

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Keleku-Lukwete Nadine Keleku Nadine

Research Projects

Research Products

Co-Researchers

Development of a novel therapy for sickle cell disease by Nrf2 activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overview of redox regulation by Keap1-Nrf2 system in toxicology and cancer.2016

Author(s)

Journal Title

Data Source

[Presentation] Nrf2 induction by oral administration of glucoraphanin relieves tissue damage in sickle cell disease.2017

Author(s)

Organizer

Data Source

[Presentation] Sulforaphane relives inflammation and organ damage in sickle cell disease by inducing Nrf2.2017

Author(s)

Organizer

Data Source

[Presentation] Insight mechanism underlying the importance of Nrf2 in sickle cell disease.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source