URANISHI KOUSUKE 浦西洸介

… Alternative Names

Uranishi Kousuke 浦西洸介

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Researcher Number	40783238
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 埼玉医科大学, 医学部, 助教 2020 – 2021: 埼玉医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related Except Principal Investigator Basic Section 48040:Medical biochemistry-related
Keywords	Principal Investigator Mga / PRC1.6 / 減数分裂 / H3K9 / Atf7ip / Setdb1 / PRC1 / 生殖細胞 / ES細胞 / T-box / bHLHZ / Stra8 / Meiosin … More Except Principal Investigator … More Myc / Max / 非典型的PRC1 / 減数分裂 / ES細胞 / 生殖細胞 Less

Elucidation of the molecular mechanisms by which germ cells inactivate the function of polycomb that acts against meiotic onset
- Principal Investigator
  
  奥田晶彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Saitama Medical University
非生殖細胞での減数分裂関連遺伝子の異所的な発現を抑制するための分子基盤の解明Principal Investigator
- Principal Investigator
  
  浦西洸介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Saitama Medical University
Analysis of the biological significance and molecular mechanisms of meiosis-specific production of Mga variants.Principal Investigator
- Principal Investigator
  
  Uranishi Kousuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Saitama Medical University

All 2024 2023 2021 2020

All Journal Article Presentation

[Journal Article] Similarity and dissimilarity in alterations of the gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane2024
- Author(s)
  Nogi Takehiro、Uranishi Kousuke、Suzuki Ayumu、Hirasaki Masataka、Nakamura Tina、Kazama Tomiei、Nagasaka Hiroshi、Okuda Akihiko、Mieda Tsutomu
- Journal Title
  
  PLOS ONE
  
  Volume: 19 Issue: 3 Pages: e0298264-e0298264
- DOI
  10.1371/journal.pone.0298264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27369
[Journal Article] MAX controls meiotic entry in sexually undifferentiated germ cells2024
- Author(s)
  Suzuki A, Uranishi K, Nishimoto M, Mizuno Y, Mizuno S, Takahashi S, Eisenman RN, Okuda A.
- Journal Title
  
  Scientific Reports
  
  Volume: 14(1) Issue: 1 Pages: 5236-5236
- DOI
  10.1038/s41598-024-55506-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06391, KAKENHI-PROJECT-21K06843, KAKENHI-PROJECT-23K27369
[Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021
- Author(s)
  Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC.
- Journal Title
  
  Nature Communications
  
  Volume: 12(1) Issue: 1 Pages: 7020-7020
- DOI
  10.1038/s41467-021-27345-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-17KK0185, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-21K06843
[Journal Article] Two DNA binding domains of MGA act in combination to suppress ectopic activation of meiosis-related genes in mouse embryonic stem cells2021
- Author(s)
  Uranishi K, Hirasaki M, Kitamura Y, Mizuno Y, Nishimoto M, Suzuki A, Okuda A.
- Journal Title
  
  Stem Cells
  
  Volume: 39(11) Issue: 11 Pages: 1435-1446
- DOI
  10.1002/stem.3433
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-20J10148, KAKENHI-PROJECT-21K06825, KAKENHI-PROJECT-21K06843
[Journal Article] Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC12021
- Author(s)
  Kitamura Y, Uranishi K, Hirasaki M, Nishimoto M, Suzuki A, Okuda A.
- Journal Title
  
  Scientific Reports
  
  Volume: 11(1) Issue: 1 Pages: 9737-9737
- DOI
  10.1038/s41598-021-89123-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-20J10148, KAKENHI-PROJECT-21K06825, KAKENHI-PROJECT-21K06843
[Presentation] Mga-Atf7ip-Setdb1 の相互作用は非生殖細胞における減数分裂関連遺伝子抑制機構の構築に寄与する2024
- Author(s)
  浦西洸介　鈴木歩　平崎正孝　西本正純　奥田晶彦
- Organizer
  第4回有性生殖研究会
- Data Source
  KAKENHI-PROJECT-23K06391
[Presentation] Mga-Atf7ip-Setsb1の相互作用は非生殖細胞における減数分裂関連遺伝子抑制機構の構築に寄与する2024
- Author(s)
  浦西洸介、鈴木歩、平崎正孝、西本正純、奥田晶彦
- Organizer
  第4回有性生殖研究会
- Data Source
  KAKENHI-PROJECT-23K27369
[Presentation] Maxによる減数分裂遺伝子の抑制制御機構2024
- Author(s)
  鈴木歩、浦西洸介、北村友佳、水野洋介、西本正純、望月健太郎、水野聖也、高橋智、奥田晶彦
- Organizer
  第4回有性生殖研究会
- Data Source
  KAKENHI-PROJECT-23K27369
[Presentation] Max による減数分裂遺伝子の抑制制御機構2024
- Author(s)
  鈴木歩　浦西洸介　北村友佳　水野洋介　西本正純　望月健太郎　水野聖也　高橋智　奥田晶彦
- Organizer
  第4回有性生殖研究会
- Data Source
  KAKENHI-PROJECT-23K06391
[Presentation] 減数分裂開始のためのポテンシャル獲得とその発揮の制御機構2023
- Author(s)
  鈴木歩　浦西洸介　北村友佳　水野洋介　西本正純　望月健太郎　水野聖也　高橋智　奥田晶彦
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K06391
[Presentation] 減数分裂開始のためのポテンシャル獲得とその発揮の制御機構2023
- Author(s)
  鈴木歩、浦西洸介、北村友佳、水野洋介、西本正純、望月健太郎、水野聖也、高橋智、奥田晶彦
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27369
[Presentation] MgaはAtf7ipとSetdb1をリクルートすることによって減数分裂関連遺伝子にH3K9me3を導入する2023
- Author(s)
  浦西洸介　鈴木歩　平崎正孝　西本正純　奥田晶彦
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K06391
[Presentation] MgaはAtf7ipとSetdb1をリクルートすることによって減数分裂関連遺伝子にH3K9me3を導入する2023
- Author(s)
  浦西洸介、鈴木歩、平崎正孝、西本正純、奥田晶彦
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27369
[Presentation] MAXによるマウス生殖細胞の減数分裂開始制御機構2021
- Author(s)
  鈴木歩　浦西洸介　北村友佳　平崎正孝　西本正純　奥田晶彦
- Organizer
  第44回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16147
[Presentation] MgaはbHLHZ領域を介してMeiosin-Stra8シグナルを制御することによって減数分裂移行を抑制する2021
- Author(s)
  浦西洸介　北村友佳　鈴木歩　平崎正孝　西本正純　奥田晶彦
- Organizer
  第44回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16147
[Presentation] Generation of meiotic germ cell-specific Mga splice variant for promoting meiotic onset via inactivation of non-canonical PRC12020
- Author(s)
  Kitamura Y, Uranishi K, Hirasaki M, Nishimoto M, Suzuki A and Okuda A
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16147
[Presentation] Identification of meiotic germ cell-specific Mga splice variant that functions as a negative regulator of non-canonical PRC1 leading to the promotion of meiotic onset2020
- Author(s)
  Kitamura Y, Uranishi K, Hirasaki M, Nishimoto M, Suzuki A and Okuda A
- Organizer
  ISSCR 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16147

1. 奥田晶彦 (60201993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 鈴木歩 (80639708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results

URANISHI KOUSUKE 浦西 洸介

Uranishi Kousuke 浦西 洸介

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanisms by which germ cells inactivate the function of polycomb that acts against meiotic onset

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非生殖細胞での減数分裂関連遺伝子の異所的な発現を抑制するための分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the biological significance and molecular mechanisms of meiosis-specific production of Mga variants.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Similarity and dissimilarity in alterations of the gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MAX controls meiotic entry in sexually undifferentiated germ cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two DNA binding domains of MGA act in combination to suppress ectopic activation of meiosis-related genes in mouse embryonic stem cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC12021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mga-Atf7ip-Setdb1 の相互作用は非生殖細胞における 減数分裂関連遺伝子抑制機構の構築に寄与する2024

Author(s)

Organizer

Data Source

[Presentation] Mga-Atf7ip-Setsb1の相互作用は非生殖細胞における減数分裂関連遺伝子抑制機構の構築に寄与する2024

Author(s)

Organizer

Data Source

[Presentation] Maxによる減数分裂遺伝子の抑制制御機構2024

Author(s)

Organizer

Data Source

[Presentation] Max による減数分裂遺伝子の抑制制御機構2024

Author(s)

Organizer

Data Source

[Presentation] 減数分裂開始のためのポテンシャル獲得とその発揮の制御機構2023

Author(s)

Organizer

Data Source

[Presentation] 減数分裂開始のためのポテンシャル獲得とその発揮の制御機構2023

Author(s)

Organizer

Data Source

[Presentation] MgaはAtf7ipとSetdb1をリクルートすることによって減数分裂関連遺伝子にH3K9me3を導入する2023

Author(s)

Organizer

Data Source

[Presentation] MgaはAtf7ipとSetdb1をリクルートすることによって減数分裂関連遺伝子にH3K9me3を導入する2023

Author(s)

Organizer

Data Source

URANISHI KOUSUKE 浦西洸介

Uranishi Kousuke 浦西洸介

[Presentation] Mga-Atf7ip-Setdb1 の相互作用は非生殖細胞における減数分裂関連遺伝子抑制機構の構築に寄与する2024

[Presentation] MgaはbHLHZ領域を介してMeiosin-Stra8シグナルを制御することによって減数分裂移行を抑制する2021