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URANISHI KOUSUKE  浦西 洸介

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Uranishi Kousuke  浦西 洸介

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Researcher Number 40783238
Other IDs
Affiliation (Current) 2025: 埼玉医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2023 – 2024: 埼玉医科大学, 医学部, 助教
2020 – 2021: 埼玉医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related
Except Principal Investigator
Basic Section 48040:Medical biochemistry-related
Keywords
Principal Investigator
Mga / PRC1.6 / 減数分裂 / H3K9 / Atf7ip / Setdb1 / PRC1 / 生殖細胞 / ES細胞 / T-box / bHLHZ / Stra8 / Meiosin … More
Except Principal Investigator
… More Myc / Max / 非典型的PRC1 / 減数分裂 / ES細胞 / 生殖細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (2 People)
  •  Elucidation of the molecular mechanisms by which germ cells inactivate the function of polycomb that acts against meiotic onset

    • Principal Investigator
      奥田 晶彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Saitama Medical University
  •  非生殖細胞での減数分裂関連遺伝子の異所的な発現を抑制するための分子基盤の解明Principal Investigator

    • Principal Investigator
      浦西 洸介
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Saitama Medical University
  •  Analysis of the biological significance and molecular mechanisms of meiosis-specific production of Mga variants.Principal Investigator

    • Principal Investigator
      Uranishi Kousuke
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Saitama Medical University

All 2024 2023 2021 2020

All Journal Article Presentation

  • [Journal Article] Similarity and dissimilarity in alterations of the gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane2024

    • Author(s)
      Nogi Takehiro、Uranishi Kousuke、Suzuki Ayumu、Hirasaki Masataka、Nakamura Tina、Kazama Tomiei、Nagasaka Hiroshi、Okuda Akihiko、Mieda Tsutomu
    • Journal Title

      PLOS ONE

      Volume: 19 Issue: 3 Pages: e0298264-e0298264

    • DOI

      10.1371/journal.pone.0298264

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27369
  • [Journal Article] MAX controls meiotic entry in sexually undifferentiated germ cells2024

    • Author(s)
      Suzuki A, Uranishi K, Nishimoto M, Mizuno Y, Mizuno S, Takahashi S, Eisenman RN, Okuda A.
    • Journal Title

      Scientific Reports

      Volume: 14(1) Issue: 1 Pages: 5236-5236

    • DOI

      10.1038/s41598-024-55506-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06391, KAKENHI-PROJECT-21K06843, KAKENHI-PROJECT-23K27369
  • [Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021

    • Author(s)
      Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC.
    • Journal Title

      Nature Communications

      Volume: 12(1) Issue: 1 Pages: 7020-7020

    • DOI

      10.1038/s41467-021-27345-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-17KK0185, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-21K06843
  • [Journal Article] Two DNA binding domains of MGA act in combination to suppress ectopic activation of meiosis-related genes in mouse embryonic stem cells2021

    • Author(s)
      Uranishi K, Hirasaki M, Kitamura Y, Mizuno Y, Nishimoto M, Suzuki A, Okuda A.
    • Journal Title

      Stem Cells

      Volume: 39(11) Issue: 11 Pages: 1435-1446

    • DOI

      10.1002/stem.3433

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-20J10148, KAKENHI-PROJECT-21K06825, KAKENHI-PROJECT-21K06843
  • [Journal Article] Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC12021

    • Author(s)
      Kitamura Y, Uranishi K, Hirasaki M, Nishimoto M, Suzuki A, Okuda A.
    • Journal Title

      Scientific Reports

      Volume: 11(1) Issue: 1 Pages: 9737-9737

    • DOI

      10.1038/s41598-021-89123-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-20J10148, KAKENHI-PROJECT-21K06825, KAKENHI-PROJECT-21K06843
  • [Presentation] Mga-Atf7ip-Setdb1 の相互作用は非生殖細胞における 減数分裂関連遺伝子抑制機構の構築に寄与する2024

    • Author(s)
      浦西洸介 鈴木歩 平崎正孝 西本正純 奥田晶彦
    • Organizer
      第4回有性生殖研究会
    • Data Source
      KAKENHI-PROJECT-23K06391
  • [Presentation] Mga-Atf7ip-Setsb1の相互作用は非生殖細胞における減数分裂関連遺伝子抑制機構の構築に寄与する2024

    • Author(s)
      浦西洸介、鈴木歩、平崎正孝、西本正純、奥田晶彦
    • Organizer
      第4回有性生殖研究会
    • Data Source
      KAKENHI-PROJECT-23K27369
  • [Presentation] Maxによる減数分裂遺伝子の抑制制御機構2024

    • Author(s)
      鈴木歩、浦西洸介、北村友佳、水野洋介、西本正純、望月健太郎、水野聖也、高橋智、奥田晶彦
    • Organizer
      第4回有性生殖研究会
    • Data Source
      KAKENHI-PROJECT-23K27369
  • [Presentation] Max による減数分裂遺伝子の抑制制御機構2024

    • Author(s)
      鈴木歩 浦西洸介 北村友佳 水野洋介 西本正純 望月健太郎 水野聖也 高橋智 奥田晶彦
    • Organizer
      第4回有性生殖研究会
    • Data Source
      KAKENHI-PROJECT-23K06391
  • [Presentation] 減数分裂開始のためのポテンシャル獲得とその発揮の制御機構2023

    • Author(s)
      鈴木歩 浦西洸介 北村友佳 水野洋介 西本正純 望月健太郎 水野聖也 高橋智 奥田晶彦
    • Organizer
      第46回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K06391
  • [Presentation] 減数分裂開始のためのポテンシャル獲得とその発揮の制御機構2023

    • Author(s)
      鈴木歩、浦西洸介、北村友佳、水野洋介、西本正純、望月健太郎、水野聖也、高橋智、奥田晶彦
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K27369
  • [Presentation] MgaはAtf7ipとSetdb1をリクルートすることによって減数分裂関連遺伝子にH3K9me3を導入する2023

    • Author(s)
      浦西洸介 鈴木歩 平崎正孝 西本正純 奥田晶彦
    • Organizer
      第46回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K06391
  • [Presentation] MgaはAtf7ipとSetdb1をリクルートすることによって減数分裂関連遺伝子にH3K9me3を導入する2023

    • Author(s)
      浦西洸介、鈴木歩、平崎正孝、西本正純、奥田晶彦
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K27369
  • [Presentation] MAXによるマウス生殖細胞の減数分裂開始制御機構2021

    • Author(s)
      鈴木歩 浦西洸介 北村友佳 平崎正孝 西本正純 奥田晶彦
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16147
  • [Presentation] MgaはbHLHZ領域を介してMeiosin-Stra8シグナルを制御することによっ て減数分裂移行を抑制する2021

    • Author(s)
      浦西洸介 北村友佳 鈴木歩 平崎正孝 西本正純 奥田晶彦
    • Organizer
      第44回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16147
  • [Presentation] Generation of meiotic germ cell-specific Mga splice variant for promoting meiotic onset via inactivation of non-canonical PRC12020

    • Author(s)
      Kitamura Y, Uranishi K, Hirasaki M, Nishimoto M, Suzuki A and Okuda A
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16147
  • [Presentation] Identification of meiotic germ cell-specific Mga splice variant that functions as a negative regulator of non-canonical PRC1 leading to the promotion of meiotic onset2020

    • Author(s)
      Kitamura Y, Uranishi K, Hirasaki M, Nishimoto M, Suzuki A and Okuda A
    • Organizer
      ISSCR 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16147
  • 1.  奥田 晶彦 (60201993)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  鈴木 歩 (80639708)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results

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