matoba takuma 的場拓磨

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Matoba Takuma 的場拓磨

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Researcher Number	40790712
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 名古屋市立大学, 医薬学総合研究院(医学), 助教 2017 – 2018: 名古屋市立大学, 大学院医学研究科, 臨床研究医
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator 抗腫瘍免疫 / 頭頸部癌 / 制御性T細胞 / CTLA-4 Except Principal Investigator 補体 / 樹状細胞 / 免疫担当細胞 / 自己免疫疾患 / 病巣感染

補体と制御性T細胞による免疫チェックポイント阻害剤の新規効果予測・治療戦略の確立
- Principal Investigator
  
  今井優樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Kyoto Tachibana University
細胞表面へのCTLA-4発現に着目した制御性T細胞を標的とする頭頸部癌治療の開発Principal Investigator
- Principal Investigator
  
  的場拓磨
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nagoya City University
Unraveling regulatory T cells in head and neck cancer -The challenge to find a new target to treat-Principal Investigator
- Principal Investigator
  
  Matoba Takuma
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nagoya City University
Mechanisms of autoimmune diseases triggered by infectious foci and treatment strategies
- Principal Investigator
  
  山崎小百合
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Nagoya City University
Investigating roles of regulatory T cells in inducing anti-tumur immunity and developing immunotherapy in head and neck cancerPrincipal Investigator
- Principal Investigator
  
  Matoba Takuma
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Impact of salvage chemotherapy after immune checkpoint inhibitor for recurrent or metastatic head and neck cancer2024
- Author(s)
  Matoba Takuma、Minohara Kiyoshi、Kawakita Daisuke、Sawabe Michi、Takano Gaku、Oguri Keisuke、Murashima Akihiro、Iwaki Sho、Tsuge Hiroshi、Imaizumi Sae、Hojo Wataru、Kondo Ayano、Tsukamoto Koji、Iwasaki Shinichi
- Journal Title
  
  Head & Neck
  
  Volume: ー Issue: 8 Pages: 1855-1864
- DOI
  10.1002/hed.27643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09731
[Journal Article] Impact of tumor burden on survival in patients with recurrent or metastatic head and neck cancer treated with immune checkpoint inhibitors2022
- Author(s)
  Matoba Takuma、Minohara Kiyoshi、Kawakita Daisuke、Takano Gaku、Oguri Keisuke、Murashima Akihiro、Nakai Kazuyuki、Iwaki Sho、Tsuge Hiroshi、Tanaka Nobukazu、Imaizumi Sae、Hojo Wataru、Matsumura Ayano、Tsukamoto Koji、Esaki Shinichi、Iwasaki Shinichi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 14319-14319
- DOI
  10.1038/s41598-022-18611-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09731, KAKENHI-PROJECT-20K10508
[Journal Article] Reply to Slominski et al.: UVB irradiation induces proenkephalin+ regulatory T cells with a wound-healing function2021
- Author(s)
  Shime Hiroaki、Odanaka Mizuyu、Tsuiji Makoto、Matoba Takuma、Imai Masaki、Yasumizu Yoshiaki、Uraki Ryuta、Minohara Kiyoshi、Watanabe Maiko、Bonito Anthony John、Fukuyama Hidehiro、Ohkura Naganari、Sakaguchi Shimon、Morita Akimichi、Yamazaki Sayuri
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 3
- DOI
  10.1073/pnas.2021919118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07510, KAKENHI-PROJECT-20K09911, KAKENHI-PROJECT-19KK0202, KAKENHI-PUBLICLY-19H04812, KAKENHI-PROJECT-20H03469, KAKENHI-PROJECT-18K16158
[Journal Article] Novel Prognostic Score for recurrent or metastatic head and neck cancer patients treated with Nivolumab2021
- Author(s)
  Minohara K, Matoba T, Kawakita D, Takano G, Oguri K, Murashima A, Nakai K, Iwaki S, Hojo W, Matsumura A, Ozaki S, Ozawa T, Harata I, Tanaka N, Maseki S, Tsuge H, Imaizumi S, Mitsuya S, Moribe K, Esaki S., Iwasaki S.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16992-16992
- DOI
  10.1038/s41598-021-96538-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-19KK0202
[Journal Article] Long-term efficacy of weekly paclitaxel therapy in unresectable primary squamous cell carcinoma of the thyroid2021
- Author(s)
  Iwaki Sho、Kawakita Daisuke、Sawabe Michi、Matoba Takuma、Takano Gaku、Oguri Keisuke、Murashima Akihiro、Minohara Kiyoshi、Tanaka Nobukazu、Tsuge Hiroshi、Imaizumi Sae、Matsumura Ayano、Masaki Ayako、Murase Takayuki、Ogawa Masaki、Iwasaki Shinichi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 3 Issue: 6 Pages: 00190-5
- DOI
  10.1016/j.anl.2021.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-19KK0202
[Journal Article] Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function2020
- Author(s)
  Shime Hiroaki、Odanaka Mizuyu、Tsuiji Makoto、Matoba Takuma、Imai Masaki、Yasumizu Yoshiaki、Uraki Ryuta、Minohara Kiyoshi、Watanabe Maiko、Bonito Anthony John、Fukuyama Hidehiro、Ohkura Naganari、Sakaguchi Shimon、Morita Akimichi、Yamazaki Sayuri
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 34 Pages: 20696-20705
- DOI
  10.1073/pnas.2000372117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07510, KAKENHI-PROJECT-20K09911, KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-19KK0202, KAKENHI-PROJECT-16H06295, KAKENHI-PUBLICLY-19H04812, KAKENHI-PROJECT-20H03469, KAKENHI-PROJECT-18K16158, KAKENHI-PROJECT-20H03703, KAKENHI-PROJECT-20K16265, KAKENHI-PROJECT-19K23868
[Journal Article] The impact of clinicopathological factors on clinical outcomes in patients with salivary gland adenoid cystic carcinoma: a multi-institutional analysis in Japan2020
- Author(s)
  Kawakita D, Murase T, Ueda K, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Matoba T, Sakurai K, Nagao T, Hanai N, Kawata R, Hato N, Nibu KI, Urano M, Taguchi KI, Nakaguro M, Kusafuka K, Yamamoto H, Nagao T, Inagaki H.
- Journal Title
  
  International Journal of Cinical Oncology
  
  Volume: 25(10) Issue: 10 Pages: 1774-1785
- DOI
  10.1007/s10147-020-01731-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-19KK0202, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-20K07417
[Journal Article] Evaluation of the modified Pittsburgh classification for predicting the disease‐free survival outcome of squamous cell carcinoma of the external auditory canal2020
- Author(s)
  Nabuurs C. H.、Kievit Wietske、Labbe Nilou、Leemans C. R.、Smit Conrad F. G. M.、Brekel Michiel W. M.、Pauw Robert J.、Laan Bernard F. A. M.、Jansen Jeroen C.、Lacko Martin、Braunius Weibel W.、Morita Shinya、Wierzbicka M.、Matoba Takuma、Hanai Nobuhiro、Takes Robert P.、Kunst Henricus P. M.
- Journal Title
  
  Head & Neck
  
  Volume: 42 Issue: 12 Pages: 3609-3622
- DOI
  10.1002/hed.26424
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-19KK0202
[Journal Article] Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer.2019
- Author(s)
  Matoba T, Imai M, Ohkura N, Kawakita D, Ijichi K, Toyama T, Morita A, Murakami S, Sakaguchi S, Yamazaki S.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 144(11) Issue: 11 Pages: 2811-2822
- DOI
  10.1002/ijc.32024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18006, KAKENHI-PROJECT-16H06295, KAKENHI-PUBLICLY-17H05798, KAKENHI-PROJECT-15H04744, KAKENHI-PROJECT-16H05177, KAKENHI-PROJECT-17K16937, KAKENHI-PROJECT-19KK0202, KAKENHI-PUBLICLY-19H04812, KAKENHI-PROJECT-17K11679
[Presentation] 免疫チェックポイント阻害薬使用後に救済化学療法を行った症例の臨床的検討2023
- Author(s)
  的場拓磨、川北大介、村嶋明大、蓑原潔、岩城翔、柘植博之、髙野学、岩﨑真一
- Organizer
  第47回日本頭頸部癌学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K09731
[Presentation] 免疫チェックポイント阻害薬使用後に成人T細胞白血病を発症した耳下腺癌例2022
- Author(s)
  的場拓磨
- Organizer
  第46回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-22K09731
[Presentation] 名古屋市立大学でニボルマブ療法を行った症例の画像所見と治療効果との関連2022
- Author(s)
  的場拓磨、川北大介、高野学、村嶋明大、蓑原潔、中井一之、青山尭央、松村綾乃、小崎晃裕、岩﨑真一
- Organizer
  第31回日本頭頸部外科学会
- Data Source
  KAKENHI-PROJECT-19KK0202
[Presentation] 名古屋市立大学でニボルマブ療法を行った症例の画像所見と治療効果との関連2022
- Author(s)
  的場拓磨、川北大介、高野学、村嶋明大、蓑原潔、中井一之、青山尭央、松村綾乃、小崎晃裕、岩﨑真一
- Organizer
  第31回日本頭頸部外科学会
- Data Source
  KAKENHI-PROJECT-19K18779
[Presentation] Skin regulatory T cells producing proenkephalin expand upon ultraviolet B exposure without ST2-IL33 axis and promote keratinocyte outgrowth.2021
- Author(s)
  Yamazaki S, Shime H, Odanaka M, Tsuiji M, Matoba T, Imai M, Yasumizu Y, Uraki R, Minohara K, Watanabe M, Bonito A, Fukuyama H, Ohkura N, Sakaguchi S, Morita A.
- Organizer
  第46回日本研究皮膚科学会
- Data Source
  KAKENHI-PROJECT-19KK0202
[Presentation] 化学放射線療法により腫瘍随伴症候群である皮膚筋炎の改善を認めた上咽頭癌例2021
- Author(s)
  的場拓磨、川北大介、高野学、蓑原潔、北條渉、松村綾乃、岩﨑真一
- Organizer
  第45回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19KK0202
[Presentation] 化学放射線療法により腫瘍随伴症候群である皮膚筋炎の改善を認めた上咽頭癌例2021
- Author(s)
  的場拓磨、川北大介、高野学、蓑原潔、北條渉、松村綾乃、岩﨑真一
- Organizer
  第45回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K18779
[Presentation] Skin regulatory T cells possessing a healing function are expanded by ultraviolet-B exposure.2020
- Author(s)
  Yamazaki S, Shime H, Odanaka M, Tsuiji M, Matoba T, Imai M, Yasumizu Y, Uraki R, Minohara K, Watanabe M, Bonito A, Fukuyama H, Ohkura N, Sakaguchi S, Morita A.
- Organizer
  第45回日本研究皮膚科学会
- Data Source
  KAKENHI-PROJECT-19KK0202
[Presentation] 名古屋市立大学関連施設におけるニボルマブの使用経験2020
- Author(s)
  的場拓磨、川北大介、髙野学、岩城翔、今泉冴恵、尾崎慎哉、小澤泰次郎、原田生功磨、欄真一郎、三矢昭治、森部一穂、岩﨑真一
- Organizer
  第44回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19KK0202
[Presentation] 名古屋市立大学関連施設におけるニボルマブの使用経験2020
- Author(s)
  的場拓磨, 川北大介, 髙野学, 岩城翔, 今泉冴恵, 尾崎慎哉, 小澤泰次郎, 原田生功磨, 欄真一郎, 三矢昭治, 森部一穂, 岩崎真一
- Organizer
  日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K18779
[Presentation] Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile is a new feature of human head and neck cancer2019
- Author(s)
  的場拓磨、今井優樹、大倉永也、川北大介、伊地知圭、遠山竜也、森田明理、村上信五、坂口志文、山崎小百合
- Organizer
  日本頭頸部癌学会基礎研究会
- Data Source
  KAKENHI-PROJECT-19K18779
[Presentation] 頭頸部癌における制御性T細胞の新たな特徴2019
- Author(s)
  的場拓磨、今井優樹、大倉永也、川北大介、伊地知圭、遠山竜也、森田明理、村上信五、坂口志文、山崎小百合
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-17K16937
[Presentation] A new feature of regulatory T cells in human head and neck cancer2018
- Author(s)
  Takuma Matoba, Masaki Imai, Naganari Ohkura, Daisuke Kawakita, Kei Ijichi, Tatsuya Toyama, Akimichi Morita, Shingo Murakami, Shimon Sakaguchi, Sayuri Yamazaki
- Organizer
  第47回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16937

1. 今井優樹 (30440936)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. 山崎小百合 (70567255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 川北大介 (70584506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 志馬寛明 (70372133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 浦木隆太 (70843027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 岩崎真一 (10359606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. OHKURA naganari

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. IJICHI kei

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TOYAMA tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. MORITA akimichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MURAKAMI shingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. SAKAGUCHI shimon

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 築地信

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 多田雄一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 稲垣宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

matoba takuma 的場 拓磨

Matoba Takuma 的場 拓磨

Research Projects

Research Products

Co-Researchers

補体と制御性T細胞による免疫チェックポイント阻害剤の新規効果予測・治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞表面へのCTLA-4発現に着目した制御性T細胞を標的とする頭頸部癌治療の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Unraveling regulatory T cells in head and neck cancer -The challenge to find a new target to treat-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of autoimmune diseases triggered by infectious foci and treatment strategies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigating roles of regulatory T cells in inducing anti-tumur immunity and developing immunotherapy in head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of salvage chemotherapy after immune checkpoint inhibitor for recurrent or metastatic head and neck cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of tumor burden on survival in patients with recurrent or metastatic head and neck cancer treated with immune checkpoint inhibitors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply to Slominski et al.: UVB irradiation induces proenkephalin+ regulatory T cells with a wound-healing function2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Prognostic Score for recurrent or metastatic head and neck cancer patients treated with Nivolumab2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term efficacy of weekly paclitaxel therapy in unresectable primary squamous cell carcinoma of the thyroid2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The impact of clinicopathological factors on clinical outcomes in patients with salivary gland adenoid cystic carcinoma: a multi-institutional analysis in Japan2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of the modified Pittsburgh classification for predicting the disease‐free survival outcome of squamous cell carcinoma of the external auditory canal2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulatory T cells expressing abundant CTLA-4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer.2019

Author(s)

Journal Title

DOI

Data Source

matoba takuma 的場拓磨

Matoba Takuma 的場拓磨