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SAKANE Chiharu  坂根 千春

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坂根 千春  サカネ チハル

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Researcher Number 40792578
Other IDs
Affiliation (Current) 2025: 長崎大学, 医歯薬学総合研究科(医歯薬学総合研究系), 助教
Affiliation (based on the past Project Information) *help 2022 – 2023: 長崎大学, 医歯薬学総合研究科(医歯薬学総合研究系), 助教
2018 – 2020: 長崎大学, 先導生命科学研究支援センター, 助教
2017: 長崎大学, 医歯薬学総合研究科(歯学系), 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Basic Section 57010:Oral biological science-related / Morphological basic dentistry
Except Principal Investigator
Basic Section 56020:Orthopedics-related
Keywords
Principal Investigator
Runx2 / 血中リン濃度制御 / エンハンサー / Fgf23 / Galnt3 / Tln2 / 骨芽細胞突起形成 / 発生・分化 / 細胞・組織 / 分化転換 / 骨芽細胞 / 軟骨細胞 … More
Except Principal Investigator
… More エンハンサー / 骨芽細胞 / I型コラーゲン Less
  • Research Projects

    (4 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (3 People)
  •  マウス生体でI型コラーゲン遺伝子発現を骨芽細胞特異的に制御するエンハンサーの同定

    • Principal Investigator
      小守 寿人
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Nagasaki University
  •  血中リン調節因子Galnt3、Fgf23遺伝子発現を制御するエンハンサーの同定Principal Investigator

    • Principal Investigator
      坂根 千春
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nagasaki University
  •  Mechanism of the regulation of osteoblast process formation by Runx2 through Tln2 regulation during osteoblast maturationPrincipal Investigator

    • Principal Investigator
      SAKANE Chiharu
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Nagasaki University
  •  Role of Runx2 in transdifferentiation from hypertrophic chondrocytes to osteoblastsPrincipal Investigator

    • Principal Investigator
      SAKANE Chiharu
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Nagasaki University

All 2024 2020 2018

All Journal Article

  • [Journal Article] Runx2 Regulates Galnt3 and Fgf23 Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf232024

    • Author(s)
      Jiang Qing、Qin Xin、Moriishi Takeshi、Fukuyama Ryo、Katsumata Shinichi、Matsuzaki Hiroshi、Komori Hisato、Matsuo Yuki、Sakane Chiharu、Ito Kosei、Hojo Hironori、Ohba Shinsuke、Komori Toshihisa
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 4 Pages: 2275-2275

    • DOI

      10.3390/ijms25042275

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K11805, KAKENHI-PROJECT-23K08591, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-23H00440
  • [Journal Article] Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice2020

    • Author(s)
      Matsuura Viviane K. S. Kawata、Yoshida Carolina Andrea、Komori Hisato、Sakane Chiharu、Yamana Kei、Jiang Qing、Komori Toshihisa
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 8 Pages: 2682-2682

    • DOI

      10.3390/ijms21082682

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09891, KAKENHI-PROJECT-20K18460, KAKENHI-PROJECT-18K17017, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-19K18946, KAKENHI-PROJECT-19K18947
  • [Journal Article] Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts.2020

    • Author(s)
      Xin Qin, Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Toshihiro Miyazaki, Hisato Komori, Kosei Ito, Klaus von der Mark, Chiharu Sakane, Hitomi Kaneko, Toshihisa Komori
    • Journal Title

      PLOS Genetics

      Volume: 16

    • NAID

      120006980742

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K18947
  • [Journal Article] Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr32018

    • Author(s)
      Kawane Tetsuya、Qin Xin、Jiang Qing、Miyazaki Toshihiro、Komori Hisato、Yoshida Carolina Andrea、Matsuura-Kawata Viviane Keiko dos Santos、Sakane Chiharu、Matsuo Yuki、Nagai Kazuhiro、Maeno Takafumi、Date Yuki、Nishimura Riko、Komori Toshihisa
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 13551-13551

    • DOI

      10.1038/s41598-018-31853-0

    • NAID

      120006987946

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19654, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-17J04196, KAKENHI-PROJECT-17K17087, KAKENHI-PROJECT-17K17094
  • 1.  小守 壽文 (00252677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  小守 寿人 (80770411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  松裏 恵子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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