MATSUO Yuki 松尾友紀

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Matsuo Yuki 松尾友紀

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Researcher Number	40792601
Other IDs
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(歯学系), 技術職員
Affiliation (based on the past Project Information) *help	2021 – 2024: 長崎大学, 医歯薬学総合研究科(歯学系), 技術職員 2018 – 2019: 長崎大学, 医歯薬学総合研究科(歯学系), 技術職員 2017: 長崎大学, 医歯薬学総合研究科(歯学系), 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 57010:Oral biological science-related / Morphological basic dentistry Except Principal Investigator Broad Section I / Basic Section 57010:Oral biological science-related / Basic Section 57060:Surgical dentistry-related / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator Runx2 / 骨芽細胞分化 / 骨形成 / 機能重複 / エンハンサー / 骨芽細胞 / P2プロモーター / P1プロモーター / 軟骨細胞 / Type II Runx2 … More / 軟骨形成 / アイソフォーム / type II Runx2 / Type I Runx2 / 基礎歯学 / 細胞・組織 / 転写活性 / 発生・分化 / 間葉系細胞 / 間葉系幹細胞 / 胎生致死 / 造血 / Supt3 … More Except Principal Investigator Runx2 / エンハンサー / Hck / Antxr1 / オステオカルシン / ヘッジホッグ / Wnt / FGF / 骨芽細胞 / アポトーシス / 血管進入 / 分化転換 / 歯学 / 発生・分化 / 細胞・組織 / 発現制御 / 軟骨細胞 / 変形性関節症 / 遺伝子発現解析 / 表面マーカー / DMP1 / 骨芽細胞分化 / コンディショナルKOマウス / Sp7 / 未分化間葉系細胞 / dentin matrix protein 1 / インディアンヘッジホッグ / 骨格系 / ヘリオキサンチン類縁体 / 多能性幹細胞 / 骨 / へリオキサンチン類縁体 Less

生体内でRunx2の骨芽細胞・軟骨細胞における機能に必須なエンハンサー領域の同定Principal Investigator
- Principal Investigator
  
  松尾友紀
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagasaki University
骨芽細胞に分化する新規DMP1陽性未分化間葉系細胞の表面マーカーと遺伝子発現解析
- Principal Investigator
  
  森石武史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Elucidation of the function of Type I Runx2 by generating knockout mice and reporter micePrincipal Investigator
- Principal Investigator
  
  Matsuo Yuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nagasaki University
Investigation of the mechanism of actions of the helioxanthin-derivative and its application as a multi-kinase inhibitor
- Principal Investigator
  
  Ohba Shinsuke
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
  Nagasaki University
Comprehensive understanding of the enhancer cluster that regulates the expression of Indian hedgehog in the skeletal system
- Principal Investigator
  
  大庭伸介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
  Nagasaki University
Elucidation of the mechanism in the regulation of chondrocyte-specific Runx2 enhancer and development of the drug for osteoarthritis
- Principal Investigator
  
  Komori Toshihisa
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Nagasaki University
Elucidation of the function of Supt3 in skeletal formation and its interaction with Runx2 promoter.Principal Investigator
- Principal Investigator
  
  MATSUO Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University

All 2024 2023 2022 2021 2018

All Journal Article Presentation

[Journal Article] Runx2 Regulates Galnt3 and Fgf23 Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf232024
- Author(s)
  Jiang Qing、Qin Xin、Moriishi Takeshi、Fukuyama Ryo、Katsumata Shinichi、Matsuzaki Hiroshi、Komori Hisato、Matsuo Yuki、Sakane Chiharu、Ito Kosei、Hojo Hironori、Ohba Shinsuke、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 4 Pages: 2275-2275
- DOI
  10.3390/ijms25042275
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11805, KAKENHI-PROJECT-23K08591, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-23H00440
[Journal Article] Modeling of intramembranous ossification using human pluripotent stem cell-derived paraxial mesoderm derivatives.2023
- Author(s)
  Ikeda Y., Tani S., Moriishi T., Kuroda A., Matsuo Y., Saeki N., Inui-Yamamoto C., Abe M., Maeda T., Rowe DW., Chung UI., Hojo H., Matsushita Y., Sawase T., Ohba S.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 24 Pages: 536-546
- DOI
  10.1016/j.reth.2023.09.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06295, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K21494
[Journal Article] Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis2023
- Author(s)
  Moriishi Takeshi、Kawai Yosuke、Fukuyama Ryo、Matsuo Yuki、He You-Wen、Akiyama Haruhiko、Asahina Izumi、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 24 Pages: 17319-17319
- DOI
  10.3390/ijms242417319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-23H00440
[Journal Article] Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs2022
- Author(s)
  Jiang Qing、Qin Xin、Nagano Kenichi、Komori Hisato、Matsuo Yuki、Taniuchi Ichiro、Ito Kosei、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 21 Pages: 13299-13299
- DOI
  10.3390/ijms232113299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-18H05283
[Journal Article] Orally administrable peptides derived from egg yolk promote skeletal repair and ameliorate degenerative skeletal disorders in mouse models2022
- Author(s)
  Kitaura Yoshiaki、Nakamura Utano、Awada Chihiro、Yamaguchi Motonori、Kim Mujo、Ikeda Yuki、Matsuo Yuki、Moriishi Takeshi、Sawase Takashi、Chung Ung-il、Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Regenerative Therapy
  
  Volume: 21 Pages: 584-595
- DOI
  10.1016/j.reth.2022.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19611, KAKENHI-PROJECT-21K19883
[Journal Article] Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading2022
- Author(s)
  Moriishi Takeshi、Ito Takuro、Fukuyama Ryo、Qin Xin、Komori Hisato、Kaneko Hitomi、Matsuo Yuki、Yoshida Noriaki、Komori Toshihisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 6 Pages: 3173-3173
- DOI
  10.3390/ijms23063173
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20K10209, KAKENHI-PROJECT-20F20407
[Journal Article] Runt‐related transcription factor‐2 (Runx2) is required for bone matrix protein gene expression in committed osteoblasts in mice2021
- Author(s)
  Qin Xin、Jiang Qing、Komori Hisato、Sakane Chiharu、Fukuyama Ryo、Matsuo Yuki、Ito Kosei、Miyazaki Toshihiro、Komori Toshihisa
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 36 Issue: 10 Pages: 2081-2095
- DOI
  10.1002/jbmr.4386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18460, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20F20407
[Journal Article] Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr32018
- Author(s)
  Kawane Tetsuya、Qin Xin、Jiang Qing、Miyazaki Toshihiro、Komori Hisato、Yoshida Carolina Andrea、Matsuura-Kawata Viviane Keiko dos Santos、Sakane Chiharu、Matsuo Yuki、Nagai Kazuhiro、Maeno Takafumi、Date Yuki、Nishimura Riko、Komori Toshihisa
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 13551-13551
- DOI
  10.1038/s41598-018-31853-0
- NAID
  120006987946
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19654, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-17J04196, KAKENHI-PROJECT-17K17087, KAKENHI-PROJECT-17K17094
[Presentation] Human pluripotent stem cell-based systems recapitulating intramembranous ossification.2023
- Author(s)
  Ikeda Y, Tani S, Moriishi T, Kuroda A, Matsuo Y, Inui C, Abe N, Maeda T, Chung UI, Hojo H, Matsushita Y, Sawase T, Ohba S
- Organizer
  International Society for Stem Cell Research 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21494

1. 森石武史 (20380983)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. Komori Toshihisa (00252677)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
3. Ohba Shinsuke (20466733)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 宮崎敏博 (10174161)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 北條宏徳 (80788422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 姜晴 (00790007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 川根徹也 (00265208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ABE Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 坂根千春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. QIN XIN

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

MATSUO Yuki 松尾 友紀

Matsuo Yuki 松尾 友紀

Research Projects

Research Products

Co-Researchers

生体内でRunx2の骨芽細胞・軟骨細胞における機能に必須なエンハンサー領域の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨芽細胞に分化する新規DMP1陽性未分化間葉系細胞の表面マーカーと遺伝子発現解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of Type I Runx2 by generating knockout mice and reporter micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the mechanism of actions of the helioxanthin-derivative and its application as a multi-kinase inhibitor

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive understanding of the enhancer cluster that regulates the expression of Indian hedgehog in the skeletal system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism in the regulation of chondrocyte-specific Runx2 enhancer and development of the drug for osteoarthritis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of Supt3 in skeletal formation and its interaction with Runx2 promoter.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Runx2 Regulates Galnt3 and Fgf23 Expressions and Galnt3 Decelerates Osteoid Mineralization by Stabilizing Fgf232024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modeling of intramembranous ossification using human pluripotent stem cell-derived paraxial mesoderm derivatives.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bcl2l1 Deficiency in Osteoblasts Reduces the Trabecular Bone Due to Enhanced Osteoclastogenesis Likely through Osteoblast Apoptosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Orally administrable peptides derived from egg yolk promote skeletal repair and ameliorate degenerative skeletal disorders in mouse models2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Runt‐related transcription factor‐2 (Runx2) is required for bone matrix protein gene expression in committed osteoblasts in mice2021

Author(s)

Journal Title

MATSUO Yuki 松尾友紀

Matsuo Yuki 松尾友紀