Yoshino Seiko 芳野聖子

Researcher Number	40793617
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 名古屋大学, 医学系研究科, 助教 2023: 名古屋大学, 医学系研究科, 助教 2021 – 2022: 名古屋大学, 医学系研究科, 特任助教 2018 – 2020: 公益財団法人がん研究会, がん研究所発がん研究部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator スーパーエンハンサー / 白血病 / ChIP-seq / C/EBPα / Hoxa9 / Trib1 / 薬剤感受性 / 統合解析 / がんゲノム / CRISPRスクリーニング … More / eccDNA / Ts1Cjeモデルマウス / ダウン症関連白血病 / Ts1Cje Less

染色体外DNAを介したがん特異的転写制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  芳野聖子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nagoya University
染色体外環状DNAによるがん悪性化進展機構の解明と治療標的としての可能性Principal Investigator
- Principal Investigator
  
  芳野聖子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nagoya University
AML malignant mechanism by enhancer reprogramming of Trib1Principal Investigator
- Principal Investigator
  
  Yoshino Seiko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nagoya University
  Japanese Foundation for Cancer Research
Trib1 functions as a critical epigenetic regulator in AMLPrincipal Investigator
- Principal Investigator
  
  Yoshino Seiko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Japanese Foundation for Cancer Research

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] BIO Clinica 第38巻7号「生体分子凝集体と染色体外環状DNA」2023
- Author(s)
  芳野聖子, 鈴木洋
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-22K07210
[Book] 実験医学部冊「リアルタイム・デジタルPCR実験スタンダード」第2部5章デジタルPCRによるmiRNAの測定2022
- Author(s)
  芳野聖子, 小松真太郎, 鈴木洋
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20K16318
[Book] 血液内科第82巻4号「Pseudokinase TRIB1による骨髄系腫瘍の発症と進展機構」2021
- Author(s)
  芳野聖子、中村卓郎
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20K16318
[Book] 血液内科第83巻1号「Trib1によるHoxa9転写制御の修飾とAML発症」2021
- Author(s)
  中村卓郎、芳野聖子
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20K16318
[Book] 臨床血液 61巻11号 Introduce My Article2020
- Author(s)
  芳野聖子、中村卓郎
- Total Pages
  1
- Publisher
  一般社団法人日本血液学会
- Data Source
  KAKENHI-PROJECT-20K16318
[Journal Article] Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma2023
- Author(s)
  Enokido Takayoshi、Horie Masafumi、Yoshino Seiko、Suzuki Hiroshi I.、Matsuki Rei、Brunnstrom Hans、Micke Patrick、Nagase Takahide、Saito Akira、Miyashita Naoya
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 22 Issue: 1 Pages: 29-40
- DOI
  10.1158/1541-7786.mcr-23-0229
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07210, KAKENHI-PROJECT-22K08277
[Journal Article] Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis2022
- Author(s)
  Kitai Hiroki、Kato Noritoshi、Ogami Koichi、Komatsu Shintaro、Watanabe Yu、Yoshino Seiko、Koshi Eri、Tsubota Shoma、Funahashi Yoshio、Maeda Takahiro、Furuhashi Kazuhiro、Ishimoto Takuji、Kosugi Tomoki、Maruyama Shoichi、Kadomatsu Kenji、Suzuki Hiroshi I.
- Journal Title
  
  BMC Biology
  
  Volume: 20 Issue: 1 Pages: 248-248
- DOI
  10.1186/s12915-022-01447-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06925, KAKENHI-PROJECT-22K07210, KAKENHI-PROJECT-21K18251
[Journal Article] The molecular understanding of super-enhancer dysregulation in cancer2022
- Author(s)
  Yoshino Seiko、Suzuki Hiroshi I.
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 84 Issue: 2 Pages: 216-229
- DOI
  10.18999/nagjms.84.2.216
- ISSN
  0027-7622
- URL
  https://nagoya.repo.nii.ac.jp/records/2002874
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07210
[Journal Article] BCL11A promotes myeloid leukemogenesis by repressing PU.1 target genes2022
- Author(s)
  Sunami Yoshitaka、Yokoyama Takashi、Yoshino Seiko、Takahara Tomoko、Yamazaki Yukari、Harada Hironori、Nakamura Takuro
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 6 Pages: 1827-1843
- DOI
  10.1182/bloodadvances.2021004558
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08824, KAKENHI-PROJECT-20K16318, KAKENHI-PROJECT-20K17389, KAKENHI-PROJECT-19H01035, KAKENHI-PROJECT-19H04355
[Journal Article] Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa92021
- Author(s)
  Yoshino Seiko、Yokoyama Takashi、Sunami Yoshitaka、Takahara Tomoko、Nakamura Aya、Yamazaki Yukari、Tsutsumi Shuichi、Aburatani Hiroyuki、Nakamura Takuro
- Journal Title
  
  Blood
  
  Volume: 137 Issue: 1 Pages: 75-88
- DOI
  10.1182/blood.2019004586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16318, KAKENHI-PROJECT-20K17389, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-19H01035
[Journal Article] Trib1 promotes the development of acute myeloid leukemia in a Ts1Cje mouse model of Down syndrome2021
- Author(s)
  Yoshino Seiko、Tanaka Miwa、Sunami Yoshitaka、Takahara Tomoko、Yamazaki Yukari、Homme Mizuki、Niibori-Nambu Akiko、Osato Motomi、Minami Takashi、Ishihara Keiichi、Nakamura Takuro
- Journal Title
  
  Leukemia
  
  Volume: 36 Issue: 2 Pages: 558-561
- DOI
  10.1038/s41375-021-01384-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-19K07702, KAKENHI-PROJECT-20K16318, KAKENHI-PROJECT-20K17389, KAKENHI-PUBLICLY-20H05521, KAKENHI-PROJECT-19H01035, KAKENHI-PROJECT-21H02917, KAKENHI-PROJECT-17K07199, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18KK0440
[Presentation] がんと相分離・スーパーエンハンサー2023
- Author(s)
  芳野聖子
- Organizer
  第83回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07210
[Presentation] Trib1によるHoxa9転写制御の修飾とAML発症機構2023
- Author(s)
  芳野聖子
- Organizer
  第83回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07210
[Presentation] Trib1はHoxa9の転写プログラムを調節することにより急性骨髄性白血病の進行を促進する2022
- Author(s)
  芳野聖子
- Organizer
  2022年度文部科学省新学術領域研究先端モデル動物支援プラットフォーム若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-22K07210
[Presentation] Trib1による骨髄系腫瘍の発症および進展機構2022
- Author(s)
  芳野聖子
- Organizer
  第4回学際的がん研究夏の学校
- Invited
- Data Source
  KAKENHI-PROJECT-22K07210
[Presentation] Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa92021
- Author(s)
  芳野聖子、横山隆志、角南義孝、高原智子、中村彩、山崎ゆかり、堤修一、油谷浩幸、中村卓郎
- Organizer
  第16回血液学若手研究者勉強会(麒麟塾)
- Invited
- Data Source
  KAKENHI-PROJECT-20K16318
[Presentation] Trib1 promotes the development of acute myeloid leukemia in the Ts1Cje Down syndrome model mouse2021
- Author(s)
  Seiko Yoshino, Miwa Tanaka, Yoshitaka Sunami, Tomoko Takahara, Yukari Yamazaki, Motomi Osato, Takashi Minami, Keiichi Ishihara and Takuro Nakamura
- Organizer
  The 39th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16318
[Presentation] Trib1による骨髄系腫瘍の発症および進展機構2021
- Author(s)
  芳野聖子、角南義孝、中村卓郎
- Organizer
  第25回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-20K16318
[Presentation] Trib1はHoxa9の転写プログラムを調節することにより急性骨髄性白血病の進行を促進する2020
- Author(s)
  芳野聖子、横山隆志, 中村卓郎
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16318
[Presentation] Trib1によるエンハンサーリプログラミングと、PROTACを用いた Trib1に対する治療法開発2020
- Author(s)
  芳野聖子、角南義孝、横山隆志、中村卓郎
- Organizer
  第24回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-18K15227
[Presentation] Trib1はAML発症においてエピゲノム修飾因子として機能する2019
- Author(s)
  芳野聖子、横山隆志, 中村卓郎
- Organizer
  平成30年度【先端モデル動物支援プラットフォーム】成果発表会
- Data Source
  KAKENHI-PROJECT-18K15227
[Presentation] エンハンサーリプログラミングを標的とするAMLの治療法開発2019
- Author(s)
  芳野聖子、横山隆志, 中村卓郎
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15227
[Presentation] Trib1 functions as a critical epigenetic regulator in AML2018
- Author(s)
  Seiko Yoshino, Takashi Yokoyama, Takuro Nakamura
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15227
[Presentation] Trib1 functions as a critical epigenetic regulator in AML2018
- Author(s)
  Seiko Yoshino, Takashi Yokoyama, Takuro Nakamura
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15227
[Presentation] Trib1 Modulates Transcriptional Functions of Hoxa9 in AML2018
- Author(s)
  Seiko Yoshino, Takashi Yokoyama, Takuro Nakamura
- Organizer
  The 9th JSH International Symposium 2018 in Kyoto
- Data Source
  KAKENHI-PROJECT-18K15227

1. HARADA Yuka

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# of Collaborated Products: 1 results
2. 尾上耕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 大里元美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 南敬

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# of Collaborated Products: 1 results
5. 原田浩徳

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# of Collaborated Products: 1 results

Yoshino Seiko 芳野 聖子

Research Projects

Research Products

Co-Researchers

染色体外DNAを介したがん特異的転写制御メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

染色体外環状DNAによるがん悪性化進展機構の解明と治療標的としての可能性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

AML malignant mechanism by enhancer reprogramming of Trib1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Trib1 functions as a critical epigenetic regulator in AMLPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] BIO Clinica 第38巻7号 「生体分子凝集体と染色体外環状DNA」2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 実験医学部冊「リアルタイム・デジタルPCR実験スタンダード」第2部5章 デジタルPCRによるmiRNAの測定2022

Author(s)

Total Pages

Publisher

Data Source

[Book] 血液内科 第82巻4号「Pseudokinase TRIB1による骨髄系腫瘍の発症と進展機構」2021

Author(s)

Total Pages

Publisher

Data Source

[Book] 血液内科 第83巻1号「Trib1によるHoxa9転写制御の修飾とAML発症」2021

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床血液 61巻11号 Introduce My Article2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The molecular understanding of super-enhancer dysregulation in cancer2022

Author(s)

Journal Title

DOI

ISSN

URL

Language

Data Source

[Journal Article] BCL11A promotes myeloid leukemogenesis by repressing PU.1 target genes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa92021

Author(s)

Journal Title

DOI

Yoshino Seiko 芳野聖子

[Book] BIO Clinica 第38巻7号「生体分子凝集体と染色体外環状DNA」2023

[Book] 実験医学部冊「リアルタイム・デジタルPCR実験スタンダード」第2部5章デジタルPCRによるmiRNAの測定2022

[Book] 血液内科第82巻4号「Pseudokinase TRIB1による骨髄系腫瘍の発症と進展機構」2021

[Book] 血液内科第83巻1号「Trib1によるHoxa9転写制御の修飾とAML発症」2021