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SAKATA Toyonori  坂田 豊典

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Sakata Toyonori  坂田 豊典

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Researcher Number 40795530
Other IDs
Affiliation (Current) 2025: 東京大学, 定量生命科学研究所, 助教
Affiliation (based on the past Project Information) *help 2025: 東京大学, 定量生命科学研究所, 助教
2022 – 2023: 東京大学, 定量生命科学研究所, 助教
2018 – 2021: 東京大学, 定量生命科学研究所, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 43050:Genome biology-related
Keywords
Principal Investigator
染色体高次構造 / コヒーシンローダー / コヒーシン / Micro-C / 転写 / エンハンサー / Hi-C / スーパーエンハンサー / SMCタンパク質 / ATPase … More / NIPBL / super-enhancer / HiChIP / メディエーター / BRD4 / CdLS Less
  • Research Projects

    (4 results)
  • Research Products

    (12 results)
  •  コヒーシンによる遺伝子の転写に伴う染色体高次構造の制御機構とその生理的機能の解明Principal Investigator

    • Principal Investigator
      坂田 豊典
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      The University of Tokyo
  •  semi-in vivo系でのコヒーシンによる染色体機能と高次構造制御機構の解明Principal Investigator

    • Principal Investigator
      坂田 豊典
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      The University of Tokyo
  •  Gene expression control mechanism via super-enhancer by cohesin loaderPrincipal Investigator

    • Principal Investigator
      Sakata Toyonori
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      The University of Tokyo
  •  Cohesin regulation in organization of 3D genome structuresPrincipal Investigator

    • Principal Investigator
      Sakata Toyonori
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2019 2018

All Journal Article Presentation

  • [Journal Article] Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors2023

    • Author(s)
      Nakato Ryuichiro、Sakata Toyonori、Wang Jiankang、Nagai Luis Augusto Eijy、Nagaoka Yuya、Oba Gina Miku、Bando Masashige、Shirahige Katsuhiko
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 5647-5647

    • DOI

      10.1038/s41467-023-41316-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06177, KAKENHI-PLANNED-20H05940, KAKENHI-PROJECT-20H05686, KAKENHI-PROJECT-23K27159
  • [Presentation] Diverse genome-wide analyses in CdLS and CHOPS syndrome reveal defects of enhancer organization mediated by cohesin2022

    • Author(s)
      Toyonori Sakata
    • Organizer
      Biochemical society scientific conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06177
  • [Presentation] コヒーシンを原因とする発生疾患の解析で明らかとなってきたコヒーシンによるエンハンサーの組織的制御2022

    • Author(s)
      坂田豊典
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06177
  • [Presentation] 遺伝情報制御ネットワークから見た病態2021

    • Author(s)
      坂田豊典、坂東優篤、白髭克彦
    • Organizer
      日本人類遺伝学会第65回大会
    • Data Source
      KAKENHI-PROJECT-20K15768
  • [Presentation] CdLS及びCHOPS症候群患者由来細胞を用いたコヒーシンによる遺伝子 発現制御メカニズムの解析2021

    • Author(s)
      坂田豊典、泉幸佑、中戸 隆一郎、鄭盛穎、坂東優 篤、白髭克彦
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K15768
  • [Presentation] Analysis of transcription and 3D genome structure in Cornelia de Lange syndrome (CdLS)2019

    • Author(s)
      Toyonori Sakata
    • Organizer
      EMBO workshop Vienna 2019 - Organization of bacterial and eukaryotic genomes by SMC complexes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14673
  • [Presentation] Genome-wide Analysis in Cohesin-related Syndromes2019

    • Author(s)
      坂田豊典
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K14673
  • [Presentation] コルネリア・デ・ランゲ症候群(CdLS)患者由来細胞における遺伝子発現制御の解析2019

    • Author(s)
      坂田豊典
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K14673
  • [Presentation] コルネリア・デ・ランゲ症候群(CdLS)患者由来細胞における遺伝子発現制御の解析2019

    • Author(s)
      坂田豊典
    • Organizer
      第37回染色体ワークショップ・ 第18回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-18K14673
  • [Presentation] Organization of 3D genome structure in Cornelia de Lange syndrome (CdLS)2018

    • Author(s)
      Toyonori Sakata
    • Organizer
      Cornelia de Lange Syndrome Foundation Scientific & Educational Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14673
  • [Presentation] コルネリア・デ・ランゲ症候群(CdLS)患者由来細胞における染色体高次構造の解析2018

    • Author(s)
      坂田豊典
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K14673
  • [Presentation] Organization of 3D genome structure in Cornelia de Lange syndrome (CdLS)2018

    • Author(s)
      Toyonori Sakata
    • Organizer
      3R3C symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14673

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