SHIMIZU MASARU 清水優

Researcher Number	40800131
Other IDs	https://orcid.org/0000-0001-8392-9242
Affiliation (based on the past Project Information) *help	2017 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 55060:Emergency medicine-related / Anesthesiology Except Principal Investigator Basic Section 55060:Emergency medicine-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator 多剤耐性 / リポソーム / 多剤耐性菌 / 重症肺炎 / 抗体療法 / drug delivery system / MRSA / 細菌性肺炎 / 分子標的療法 / 急性肺障害 / Ⅲ型分泌システム / 免疫療法 / 緑膿菌 … More Except Principal Investigator … More 肺炎 / 急性肺傷害 / グラム陰性菌 / 三型分泌システム / 多剤耐性菌 / 重症肺炎 / 緑膿菌 / 重症感染症 / 血清抗体価 / ガンマグロブリン療法 / 抗体療法 / 抗原 / 免疫療法 / 抗体価 / 3型分泌システム / 細菌性肺炎 / PcrV / 受動免疫 / Ⅲ型分泌システム / ガンマグロブリン / 抗菌薬 / 薬剤耐性菌 / バクテリオファージ / 敗血症 / 耐性菌 / 動物モデル / III型分泌システム / ファージ療法 / 抗菌療法 / 三型分泌毒素 / 薬剤耐性 / 緑膿菌性肺炎 / バクテリオファージ療法 Less

Preclinical trial of bacteriophage therapy against severe Pseudomonas aeruginosa pnneumoina
- Principal Investigator
  
  Sawa Teiji
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Development of Combined Antibody Therapy Using DDS for MRSA PneumoniaPrincipal Investigator
- Principal Investigator
  
  SHIMIZU MASARU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kyoto Prefectural University of Medicine
An epidemiological investigation of serum titers of anti-Pseudomonas aeruginosa virulent antigens and a trial of a specific anti-Pseuomonal gamma-globulin product
- Principal Investigator
  
  Sawa Teiji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kyoto Prefectural University of Medicine
緑膿菌性肺炎に対する分子標的抗菌薬の開発Principal Investigator
- Principal Investigator
  
  清水優
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Anesthesiology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Effect of a Novel Trivalent Vaccine Formulation against Acute Lung Injury Caused by Pseudomonas aeruginosa2023
- Author(s)
  Inoue Keita、Kinoshita Mao、Muranishi Kentaro、Ohara Junya、Sudo Kazuki、Kawaguchi Ken、Shimizu Masaru、Naito Yoshifumi、Moriyama Kiyoshi、Sawa Teiji
- Journal Title
  
  Vaccines
  
  Volume: 11 Issue: 6 Pages: 1088-1088
- DOI
  10.3390/vaccines11061088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16593, KAKENHI-PROJECT-18K19590, KAKENHI-PROJECT-23K24435
[Journal Article] Myocardial injury in a patient with severe coronavirus disease: A case report2021
- Author(s)
  Nakamura Yuki、Shimizu Masaru、Yamaki Taeka、Kushimoto Kohsuke、Yamashita Ayahiro、Hayase Kazuma、Yamazaki Masaki、Hashimoto Satoru、Ohta Bon
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 2 Pages: 364-368
- DOI
  10.1016/j.jiac.2020.09.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16545
[Journal Article] Secondary in-hospital epidemiological investigation after an outbreak of Pseudomonas aeruginosa ST3572020
- Author(s)
  Mihara T, Kimura T, Momiyama K, Kainuma A, Akiyama K, Ohara J, Inoue K, Kinoshita M, Shimizu M, Moriyama K, Fujita N, Sawa T.
- Journal Title
  
  J Infect Chemother
  
  Volume: 26 Issue: 3 Pages: 257-265
- DOI
  10.1016/j.jiac.2019.09.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19590, KAKENHI-PROJECT-18K16521, KAKENHI-PROJECT-18H02905, KAKENHI-PROJECT-18K16545
[Journal Article] 各種病原性グラム陰性菌V抗系で免疫化したマウスによる交差抗原性についての検討2020
- Author(s)
  木下真央, 小原潤也, 三原聡仁, 井上敬太, 清水優, 佐和貞治
- Journal Title
  
  緑膿菌感染症研究会講演記録 54回
  
  Volume: 54 Pages: 91-93
- Data Source
  KAKENHI-PROJECT-18K16545
[Journal Article] Epidemiological survey of serum titers from adults against various Gram-negative bacterial V-antigens.2020
- Author(s)
  Kinoshita M, Shimizu M, Akiyama K, Kato H, Moriyama K, Sawa T.
- Journal Title
  
  PLoS One
  
  Volume: 15 Issue: 3 Pages: 15-15
- DOI
  10.1371/journal.pone.0220924
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19590, KAKENHI-PROJECT-17K16747, KAKENHI-PROJECT-18K16521, KAKENHI-PROJECT-20K17903, KAKENHI-PROJECT-18K16545, KAKENHI-PROJECT-18H02905
[Journal Article] Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study2019
- Author(s)
  Shimizu Masaru、Amaya Fumimasa、Kinoshita Mao、Yamasaki Masaki、Yokota Isao、Sawa Teiji
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 10 Pages: 0223947-0223947
- DOI
  10.1371/journal.pone.0223947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19704, KAKENHI-PROJECT-17K16746, KAKENHI-PROJECT-18K16521, KAKENHI-PROJECT-18K16545, KAKENHI-PROJECT-18H02899
[Journal Article] 当院で分離された薬剤耐性緑膿菌株にけるclass 1 integron遺伝子解析2019
- Author(s)
  三原聡仁, 甲斐沼篤, 籾山恭子, 小原潤也, 井上敬太, 木下真央, 清水優, 木村武史, 佐和貞治.
- Journal Title
  
  第53回緑膿菌感染症研究会公演記録
  
  Volume: 53 Pages: 55-57
- Data Source
  KAKENHI-PROJECT-18H02905
[Journal Article] The protective effects of nasal PcrV-CpG oligonucleotide vaccination against Pseudomonas aeruginosa pneumonia.2018
- Author(s)
  Naito Y, Hamaoka S, Kinoshita M, Kainuma A, Shimizu M, Katoh H, Moriyama K, Ishii KJ, Sawa T.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 12 Issue: 12 Pages: 774-785
- DOI
  10.1111/1348-0421.12658
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16747, KAKENHI-PROJECT-18K16521, KAKENHI-PROJECT-18K16545, KAKENHI-PROJECT-18H02905
[Journal Article] An outbreak of fluoroquinolone-resistant Pseudomonas aeruginosa ST357 harboring the exoU gene.2018
- Author(s)
  Kainuma A, Momiyama K, Kimura T, Akiyama K, Inoue K, Naito Y, Kinoshita M, Shimizu M, Kato H, Shime N, Fujita N, Sawa T.
- Journal Title
  
  J Infect Chemother.
  
  Volume: in press Issue: 8 Pages: 615-622
- DOI
  10.1016/j.jiac.2018.03.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05008, KAKENHI-PROJECT-26670791, KAKENHI-PROJECT-18K19590, KAKENHI-PROJECT-18K16521, KAKENHI-PROJECT-18K16545, KAKENHI-PROJECT-18H02905
[Journal Article] The protective effects of nasal PcrV-CpG oligonucleotide vaccination against Pseudomonas aeruginosa pneumonia.2018
- Author(s)
  Naito Y, Hamaoka S, Kinoshita M, Kainuma A, Shimizu M, Katoh H, Moriyama K, Ishii KJ, Sawa T.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 62 Pages: 774-785
- NAID
  40021778113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19590
[Journal Article] Flow-dynamics assessment of mitral-valve surgery by intraoperative vector flow mapping2017
- Author(s)
  Akiyama K, Nakamura N, Itatani K, Naito Y, Kinoshita M, Shimizu M, Hamaoka S, Kato H, Yasumoto H, Nakajima Y, Mizobe T, Numata S, Yaku H, Sawa T.
- Journal Title
  
  Int Cardiovasc Thorac Surg
  
  Volume: in press Issue: 6 Pages: 869-875
- DOI
  10.1093/icvts/ivx033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861232, KAKENHI-PROJECT-16K10970, KAKENHI-PROJECT-17K11097, KAKENHI-PROJECT-17H07015, KAKENHI-PROJECT-26462761
[Journal Article] Efficacy comparison of adjuvants in PcrV vaccine against Pseudomonas aeruginosa pneumonia.2017
- Author(s)
  Hamaoka S, Niato Y, Katoh H, Shimizu M, Kinoshita M, Kainuma A, Akiyama K, Sawa T.
- Journal Title
  
  Microbial Immunol
  
  Volume: 61 Issue: 2 Pages: 64-74
- DOI
  10.1111/1348-0421.12467
- NAID
  40021166122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05008, KAKENHI-PROJECT-17H07015, KAKENHI-PROJECT-26670791
[Journal Article] 各種グラム陰性細菌V抗原抗体価の疫学調査2017
- Author(s)
  木下真央, 甲斐沼篤, 内藤慶史, 秋山浩一, 濱岡早枝子, 清水優, 加藤秀哉, 佐和貞治
- Journal Title
  
  緑膿菌感染症研究会講演記録
  
  Volume: 51 Pages: 96-97
- Data Source
  KAKENHI-PROJECT-17H07015
[Journal Article] Vector flow mapping and impaired left ventricular flow by Alfieri stitch.2017
- Author(s)
  Akiyama K, Itatani K, Naito Y, Kinoshita M, Shimizu M, Hamaoka S, Yasumoto H, Kato H, Nakajima Y, Numata S, Yaku H, Sawa T.
- Journal Title
  
  J Cardiothorac Vasc Anesth
  
  Volume: in press Issue: 1 Pages: 211-214
- DOI
  10.1053/j.jvca.2016.07.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861232, KAKENHI-PROJECT-16K10970, KAKENHI-PROJECT-17H07015
[Presentation] 当院におけるMRSA（メチシリン耐性黄色ブドウ球菌）における血液培養陽性患者の解析2020
- Author(s)
  清水　優
- Organizer
  第47回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16545
[Presentation] Effects of phage therapy and antibiotics against acute pneumonia caused by MRSA in leukopenic mice2020
- Author(s)
  Masaru Shimizu, Mao Kinoshita, Hideya Kato, Junya Ohara, Keita Inoue, Toshihito Mihara, Jumpei Fujiki, Hidetomo Iwano, Teiji Sawa
- Organizer
  International Anesthesia Research Society (IARS) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16545
[Presentation] 緑膿菌感染症の抗体価推移からみる呼吸器感染病態2020
- Author(s)
  木下真央, 清水優,他
- Organizer
  日本麻酔科学会第67回学術集会
- Data Source
  KAKENHI-PROJECT-18K16545
[Presentation] 抗菌薬に頼らない新治療法ファージセラピー : 免疫抑制マウスを用いたMRSA肺炎での検討2020
- Author(s)
  清水優, 木下真央, 藤木純平, 佐和貞治
- Organizer
  日本麻酔科学会第67回学術集会
- Data Source
  KAKENHI-PROJECT-18K16545
[Presentation] MRSAの血液培養陽性患者の解析：単施設後方的観察研究2020
- Author(s)
  清水優, 木下真央, 三原聡仁, 橋本悟, 佐和貞治
- Organizer
  第47回日本集中治療医学会学術集会,名古屋(web開催)
- Data Source
  KAKENHI-PROJECT-18K16545
[Presentation] Energetic performance index improvement after Glenn and Damus-Kaye-Stansel procedure using vector flow mapping analysis.2018
- Author(s)
  Kainuma A, Hayase K, Akiyama K, Naito Y, Shimizu M, Itatani K, Sawa T.
- Organizer
  IARS 2018. Annual Meeting and International Science Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02905
[Presentation] 膝関節鏡下手術を施行した患者のPONVの発生頻度とリスク因子の検討2017
- Author(s)
  清水優, 木下真央, 飯田淳, 鳥居ゆき, 佐竹早紀子, 竹下秀祐, 加藤秀哉, 柴禄郎
- Organizer
  日本臨床麻酔学会第37回大会
- Data Source
  KAKENHI-PROJECT-17H07015
[Presentation] 大動脈弁置換術後の急性肝障害を契機に発見された下大静脈狭窄に対して外科的修復術を行った1例2017
- Author(s)
  串本洸輔, 木下真央, 井上敬太, 青山典子, 荻野壮輔, 荒井美香, 清水優, 阪口雅洋
- Organizer
  日本臨床麻酔学会第37回大会
- Data Source
  KAKENHI-PROJECT-17H07015
[Presentation] 各種グラム陰性細菌V抗原抗体価の疫学調査2017
- Author(s)
  木下真央, 甲斐沼篤, 内藤慶史, 秋山浩一, 濱岡早枝子, 清水優, 加藤秀哉, 佐和貞治
- Organizer
  緑膿菌感染症研究会第51回
- Data Source
  KAKENHI-PROJECT-17H07015
[Presentation] 特殊疾患　尿素サイクル異常症(高アルギニン血症)患者の麻酔経験2017
- Author(s)
  川口顕, 清水優, 木下真央, 加藤秀哉, 中山力恒, 加藤裕紀子, 須藤和樹, 中山綾子, 佐和貞治
- Organizer
  日本小児麻酔学会第23回大会
- Data Source
  KAKENHI-PROJECT-17H07015
[Presentation] 挿管困難の既往があるBeckwith-Wiedemann症候群の乳児における気道管理2017
- Author(s)
  印藤孝介, 清水優, 板東瑞樹, 村上敬之, 加藤秀哉, 佐和貞治
- Organizer
  日本麻酔科学会第63回関西支部学術集会
- Data Source
  KAKENHI-PROJECT-17H07015

1. Sawa Teiji (10206013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. 木下真央 (20816384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 藤木純平 (30805114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 岩野英知 (60382488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 森山潔 (10296717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 天谷文昌 (60347466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. ITATANI Keiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 加藤秀哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMIZU MASARU 清水 優

Research Projects

Research Products

Co-Researchers

Preclinical trial of bacteriophage therapy against severe Pseudomonas aeruginosa pnneumoina

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Combined Antibody Therapy Using DDS for MRSA PneumoniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An epidemiological investigation of serum titers of anti-Pseudomonas aeruginosa virulent antigens and a trial of a specific anti-Pseuomonal gamma-globulin product

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

緑膿菌性肺炎に対する分子標的抗菌薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of a Novel Trivalent Vaccine Formulation against Acute Lung Injury Caused by Pseudomonas aeruginosa2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myocardial injury in a patient with severe coronavirus disease: A case report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Secondary in-hospital epidemiological investigation after an outbreak of Pseudomonas aeruginosa ST3572020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 各種病原性グラム陰性菌V抗系で免疫化したマウスによる交差抗原性についての検討2020

Author(s)

Journal Title

Data Source

[Journal Article] Epidemiological survey of serum titers from adults against various Gram-negative bacterial V-antigens.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 当院で分離された薬剤耐性緑膿菌株にけるclass 1 integron遺伝子解析2019

Author(s)

Journal Title

Data Source

[Journal Article] The protective effects of nasal PcrV-CpG oligonucleotide vaccination against Pseudomonas aeruginosa pneumonia.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An outbreak of fluoroquinolone-resistant Pseudomonas aeruginosa ST357 harboring the exoU gene.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The protective effects of nasal PcrV-CpG oligonucleotide vaccination against Pseudomonas aeruginosa pneumonia.2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Flow-dynamics assessment of mitral-valve surgery by intraoperative vector flow mapping2017

Author(s)

Journal Title

DOI

SHIMIZU MASARU 清水優

[Presentation] 特殊疾患　尿素サイクル異常症(高アルギニン血症)患者の麻酔経験2017