Takatani Naoki 高谷直己

Researcher Number	40801501
Other IDs
Affiliation (Current)	2025: 北海道大学, 水産科学研究院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 北海道大学, 水産科学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 40040:Aquatic life science-related / 0603:Forestry and forest products science, applied aquatic science, and related fields Except Principal Investigator Basic Section 40040:Aquatic life science-related
Keywords	Principal Investigator フコキサンチン / 海洋性カロテノイド / 認知機能 / 神経変性疾患 / ミトコンドリア / ミクログリア / 腸内細菌 / 腸腎連関 / 慢性炎症 / マクロファージ … More / 抗炎症作用 / CKD / 線維化 / 炎症 / カロテノイド生体内代謝物 / 慢性腎臓病 / フコキサンチノール … More Except Principal Investigator 免疫応答因子 / オルガネラ / フコキサンチン脂肪酸エステル / 樹状細胞 / 免疫老化 / アマロウシアキサンチンA / フコキサンチノール / 炎症抑制 / 免疫細胞 / 褐藻 / 抗炎症作用 / 加齢肥満予防 / T細胞 / マクロファージ / イムノカロテノイド / フコキサンチン Less

Elucidation of preventive mechanisms for neurodegenerative diseases through regulation of microglial function by marine carotenoidsPrincipal Investigator
- Principal Investigator
  
  高谷直己
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Hokkaido University
Prevention of chronic kidney disease through regulation of gut-kidney axis by marine carotenoidsPrincipal Investigator
- Principal Investigator
  
  Takatani Naoki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0603:Forestry and forest products science, applied aquatic science, and related fields
- Research Institution
  Hokkaido University
Functional regulation of immune cells in the metabolic disease prevention mechanism by brown seaweed fucoxanthin
- Principal Investigator
  
  Hosokawa Masashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] 「カロテノイドの科学―基礎，研究の新展開，生理活性～―」2024
- Author(s)
  高市真一、眞岡孝至、新藤一敏、藤井律子、出羽毅久、近藤政晴、川﨑信治、豊島拓樹、作道隆、川田紘次郎、伊藤晋作、吉澤晋、蓮沼誠久、石原大地、長島綾、梅野太輔、竹村美保、古林真衣子、本田真己、井上拓郎、加藤雅也、馬剛、張嵐翠、尾花明、細川雅史、高谷直己、真鍋祐樹、菅原達也、前多隼人、内藤裕二、西田康宏、桑原大知、平澤和明
- Total Pages
  275
- Publisher
  シーエムシー出版
- ISBN
  9784781317984
- Data Source
  KAKENHI-PROJECT-21H02276
[Journal Article] Identification of a novel monocyclic carotenoid and prediction of its biosynthetic genes in Algoriphagus sp. oki452024
- Author(s)
  Takatani Naoki、Maoka Takashi、Sawabe Tomoo、Beppu Fumiaki、Hosokawa Masashi
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 108 Issue: 1 Pages: 1-10
- DOI
  10.1007/s00253-023-12995-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14018
[Journal Article] Reduction of serum lipid levels in diabetic obese KK-Ay mice using monoalkyldiacylglycerol-rich oil derived from Berryteuthis magister2023
- Author(s)
  Masaki Kakimoto, Naoki Takatani, Masashi Hosokawa and Fumiaki Beppu
- Journal Title
  
  Fisheries Science
  
  Volume: 89 Issue: 2 Pages: 243-251
- DOI
  10.1007/s12562-022-01655-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06221, KAKENHI-PROJECT-21K20589
[Journal Article] Identification and Tissue Distribution of Fucoxanthinol and Amarouciaxanthin A Fatty Acid Esters in Fucoxanthin-fed Mice2023
- Author(s)
  Takatani Naoki、Sakimura Kana、Nagata Kodai、Beppu Fumiaki、Yamano Yumiko、Maoka Takashi、Hosokawa Masashi
- Journal Title
  
  Food Chemistry
  
  Volume: 410 Pages: 135318-135318
- DOI
  10.1016/j.foodchem.2022.135318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02276, KAKENHI-PROJECT-21K20589
[Journal Article] Effect of heat processing conditions on the anti-obesity activity of kombu in diet-induced obese mice2023
- Author(s)
  Tojo Yuka、Kamitani Toshiaki、Takatani Naoki、Toda Toshiya、Suzuki Toshio、Aoe Seiichiro
- Journal Title
  
  FSTR
  
  Volume: 29 Issue: 4 Pages: 331-337
- DOI
  10.3136/fstr.FSTR-D-22-00222
- ISSN
  1344-6606, 1881-3984
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14018
[Journal Article] アポカロテノイドの細胞機能調節作用2023
- Author(s)
  高谷直己
- Journal Title
  
  アグリバイオ
  
  Volume: 7 Pages: 338-341
- Data Source
  KAKENHI-PROJECT-21K20589
[Journal Article] Monocaprin Enhances Bioavailability of Fucoxanthin in Diabetic/Obese KK-Ay Mice2022
- Author(s)
  Nagata Kodai、Takatani Naoki、Beppu Fumiaki、Abe Aya、Tominaga Etsuko、Fukuhara Tomohisa、Ozeki Makoto、Hosokawa Masashi
- Journal Title
  
  Marine Drugs
  
  Volume: 20 Issue: 7 Pages: 446-446
- DOI
  10.3390/md20070446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02276, KAKENHI-PROJECT-21K20589
[Journal Article] Preparation of Apoastaxanthinals and Evaluation of Their Anti-inflammatory Action against Lipopolysaccharide-Stimulated Macrophages and Adipocytes2022
- Author(s)
  Takatani Naoki、Beppu Fumiaki、Yamano Yumiko、Maoka Takashi、Miyashita Kazuo、Hosokawa Masashi
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 26 Pages: 22341-22350
- DOI
  10.1021/acsomega.2c01164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02276, KAKENHI-PROJECT-21K20589
[Journal Article] Seco-type β-Apocarotenoid Generated by β-Carotene Oxidation Exerts Anti-inflammatory Effects against Activated Macrophages2021
- Author(s)
  Takatani Naoki、Beppu Fumiaki、Yamano Yumiko、Maoka Takashi、Hosokawa Masashi
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 70 Issue: 4 Pages: 549-558
- DOI
  10.5650/jos.ess20329
- NAID
  130008020860
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06221, KAKENHI-PROJECT-18H02274, KAKENHI-PROJECT-19J11147, KAKENHI-PROJECT-21K20589
[Journal Article] n-3 Polyunsaturated fatty acid-enriched phosphatidylglycerol suppresses inflammation in RAW264.7 cells through Nrf2 activation via alteration of fatty acids in cellular phospholipids2021
- Author(s)
  Chen Liping、Beppu Fumiaki、Takatani Naoki、Miyashita Kazuo、Hosokawa Masashi
- Journal Title
  
  Fisheries Science
  
  Volume: 87 Issue: 5 Pages: 727-737
- DOI
  10.1007/s12562-021-01542-5
- NAID
  40022692351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 北太平洋に分布する動物プランクトン群集の脂質特性分析2024
- Author(s)
  笹川拓真・山口篤・高谷直己・細川雅史・別府史章
- Organizer
  令和6年度日本水産学会大会春季大会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] 海洋細菌が産生する希少カロテノイドの同定と抗炎症活性評価2024
- Author(s)
  高谷直己・別府史章・細川雅史.
- Organizer
  令和6年度日本水産学会大会春季大会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] Identification and tissue distribution of fucoxanthin-derived novel metabolites2023
- Author(s)
  Naoki Takatani, Kana Sakimura, Fumiaki Beppu, Yumiko Yamano, Takashi Maoka, Masashi Hosokawa
- Organizer
  The 19th International Symposium on Carotenoids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] C2C12筋芽細胞におけるアルキルグリセロールの筋管サイズ増大効果とリン脂質代謝調節作用2023
- Author(s)
  佐々木健朗・亀山美宇・高谷直己・細川雅史・別府史章
- Organizer
  日本油化学会第61回年会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] フコキサンチンの非アルコール性脂肪性肝炎モデルマウスに対する予防機構2023
- Author(s)
  池田詩歩・高谷直己・別府史章・細川雅史
- Organizer
  日本油化学会第61回年会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] α-リノレン酸の細胞内変換を促進する食品成分の探索と制御機構の解明2023
- Author(s)
  小関万葉・高谷直己・別府史章・細川雅史
- Organizer
  日本油化学会第61回年会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] 海洋性カロテノイドastaxanthinの生体内代謝物の同定と組織分布2023
- Author(s)
  高谷直己、向村　奏、別府史章、細川雅史
- Organizer
  令和5年度日本水産学会大会春季大会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] 海洋性カロテノイドastaxanthinの生体内代謝物の同定と組織分布2023
- Author(s)
  高谷直己・向村奏・別府史章・細川雅史
- Organizer
  令和５年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] フコキサンチンの非アルコール性脂肪肝炎モデルマウスに対する予防機構2023
- Author(s)
  池田詩歩・高谷直己・別府史章・細川雅史
- Organizer
  第9回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] Fucoxanthinおよびその代謝物による樹状細胞の炎症制御作用2023
- Author(s)
  七戸優斗・高谷直己・別府史章・細川雅史
- Organizer
  日本油化学会第61回年会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] アスタキサンチン由来アポカロテノイドの調製と生理活性評価2023
- Author(s)
  高谷直己・別府史章・山野由美子・眞岡孝至・細川雅史.
- Organizer
  第35回カロテノイド研究談話会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] Identification of novel monocyclic carotenoids in marine bacteria and their bioactivity2023
- Author(s)
  Masashi Hosokawa, Naoki Takatani, Fumiaki Beppu
- Organizer
  2023 AOCS Annual Meeting & Expo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] Identification and tissue distribution of fucoxanthin-derived novel metabolites2023
- Author(s)
  Naoki Takatani, Kana Sakimura, Fumiaki Beppu, Yumiko Yamano, Takashi Maoka, Masashi Hosokawa
- Organizer
  The 19th International Symposium on Carotenoids
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] アスタキサンチン由来アポカロテノイドの調製と生理活性評価2023
- Author(s)
  高谷直己、別府史章、山野由美子、眞岡孝至、細川雅史
- Organizer
  第35回カロテノイド研究談話会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] フコキサンチンの非アルコール性脂肪性肝炎モデルマウスに対する予防機構2023
- Author(s)
  池田詩歩、高谷直己、別府史章、細川雅史
- Organizer
  第61回日本油化学会年会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] Identification of novel and rare carotenoids from marine bacteria and their biosynthesis2023
- Author(s)
  Naoki Takatani
- Organizer
  Taiwan-Japan International Symposium on Marine Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] フコキサンチン由来生体内開裂物の同定と活性化マクロファージおよび脂肪細胞に対する抗炎症作用2023
- Author(s)
  高谷直己・別府史章・細川雅史
- Organizer
  第9回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] 海洋細菌が産生するn-3系多価不飽和脂肪酸含有脂質の生体内蓄積と糖・脂質代謝改善作用2023
- Author(s)
  佐藤花奈・別府史章・高谷直己・吉川典孝・相馬邦彦・池口主弥・細川雅史
- Organizer
  日本油化学会第61回年会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] 海洋性カロテノイドastaxanthinの生体内代謝物の同定と組織分布2023
- Author(s)
  高谷直己、向村奏、別府史章、細川雅史
- Organizer
  令和5年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] Fucoxanthinおよびその代謝物による樹状細胞の炎症制御作用2023
- Author(s)
  七戸優斗、高谷直己、別府史章、細川雅史
- Organizer
  第61回日本油化学会年会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] n-3PUFA 結合ホスファチジルグリセロールの細胞内脂肪酸調節機構の解明2023
- Author(s)
  富樫咲、別府史章、高谷直己、細川雅史
- Organizer
  令和5年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 海洋細菌Algoriphagus sp. oki45株が産生する新規カロテノイドの同定と生合成遺伝子の推定2023
- Author(s)
  高谷直己・土橋祐汰・澤辺智雄・眞岡孝至・別府史章・細川雅史
- Organizer
  日本油化学会第61回年会
- Data Source
  KAKENHI-PROJECT-23K14018
[Presentation] Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in macrophages treated with apocarotenoids2022
- Author(s)
  Hiroki Miyafusa、Naoki Takatani、Fumiaki Beppu、Yumiko Yamano、Masashi Hosokawa
- Organizer
  The 2nd World Congress on Oleo Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] イトマキヒトデ脂質成分によるC2C12細胞の筋管形成促進効果2022
- Author(s)
  別府史章, 福島葵, 高谷直己, 細川雅史
- Organizer
  令和4年度公益社団法人日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 水産物由来アルキルグリセロールによるC2C12筋管サイズ増大効果2022
- Author(s)
  佐々木健朗、亀山美宇、高谷直己、細川雅史、別府史章
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] Activation of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in Macrophages Treated with Apocarotenoids2022
- Author(s)
  Miyafusa Hiroki, Takatani Naoki, Beppu Fumiaki, Yamano Yumiko, Hosokawa Masashi
- Organizer
  The 2nd World Congress on Oleo Science, WCOS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] Identification of novel carotenoids from marine bacteria and their bioactivity2022
- Author(s)
  Takatani Naoki、Hosokawa Masashi
- Organizer
  The 2nd World Congress on Oleo Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 高度不飽和ホスファチジルグリセロールの抗炎症作用に関わる細胞内n-3系脂肪酸強化2022
- Author(s)
  富樫咲、陳莉萍、別府史章、高谷直己、細川雅史
- Organizer
  2022年度第4回脂質駆動学術産業創生研究部会講演会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 海洋性カロテノイドfucoxanthinの新規生体内代謝物の同定と組織分布解析2022
- Author(s)
  高谷直己、向村　奏、永田航大、田谷大輔、別府史章、細川雅史
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] フコキサンチン由来新規生体内代謝物の同定と組織分布解析2022
- Author(s)
  高谷直己、向村　奏、別府史章、山野由美子、眞岡孝至、細川雅史
- Organizer
  第34回カロテノイド研究談話会
- Data Source
  KAKENHI-PROJECT-21H02276
[Presentation] フコキサンチン由来新規生体内代謝物の同定と組織分布解析2022
- Author(s)
  高谷直己、向村奏、別府史章、山野由美子、眞岡孝至、細川雅史
- Organizer
  第34回カロテノイド研究談話会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 海洋性カロテノイドfucoxanthinの新規生体内代謝物の同定と組織分布解析2022
- Author(s)
  高谷直己、向村奏、永田航大、田谷大輔、別府史章、細川雅史
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] n-3 系多価不飽和脂肪酸と β-コングリシニンの併用による糖・脂質代謝改善効果2021
- Author(s)
  谷脇拓実, 和根崎智, 高谷直己, 別府史章, 細川雅史
- Organizer
  日本油化学会第60回年会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 生体内におけるフコキサンチン代謝物の構造解析2021
- Author(s)
  向村奏, 永田航大, 高谷直己, 別府史章, 細川雅史
- Organizer
  2021年度日本農芸化学会北海道支部第1回学術講演会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] n-3 系多価不飽和脂肪酸結合ホスファチジルグリセロールの細胞内脂肪酸修飾と抗炎症作用2021
- Author(s)
  富樫咲, 陳莉萍, 別府史章, 高谷直己, 細川雅史
- Organizer
  日本油化学会第60回年会
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] Identification of novel fucoxanthin cleavage metabolites and anti-inflammatory action against activated macrophages2021
- Author(s)
  Naoki Takatani, Fumiaki Beppu, Takashi Okitsu, Yumiko Yamano, and Masashi Hosokawa
- Organizer
  The 1st Virtual International Conference on Carotenoids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20589
[Presentation] 褐藻由来フコキサンチンによる非アルコール性脂肪肝炎抑制効果2021
- Author(s)
  高谷直己, 別府史章, 細川雅史
- Organizer
  第7回北海道大学部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-21K20589

1. Hosokawa Masashi (10241374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 岡松優子 (90527178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 別府史章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takatani Naoki 高谷 直己

Research Projects

Research Products

Co-Researchers

Elucidation of preventive mechanisms for neurodegenerative diseases through regulation of microglial function by marine carotenoidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prevention of chronic kidney disease through regulation of gut-kidney axis by marine carotenoidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional regulation of immune cells in the metabolic disease prevention mechanism by brown seaweed fucoxanthin

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 「カロテノイドの科学―基礎，研究の新展開，生理活性～―」2024

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Identification of a novel monocyclic carotenoid and prediction of its biosynthetic genes in Algoriphagus sp. oki452024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduction of serum lipid levels in diabetic obese KK-Ay mice using monoalkyldiacylglycerol-rich oil derived from Berryteuthis magister2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and Tissue Distribution of Fucoxanthinol and Amarouciaxanthin A Fatty Acid Esters in Fucoxanthin-fed Mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of heat processing conditions on the anti-obesity activity of kombu in diet-induced obese mice2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] アポカロテノイドの細胞機能調節作用2023

Author(s)

Journal Title

Data Source

[Journal Article] Monocaprin Enhances Bioavailability of Fucoxanthin in Diabetic/Obese KK-Ay Mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preparation of Apoastaxanthinals and Evaluation of Their Anti-inflammatory Action against Lipopolysaccharide-Stimulated Macrophages and Adipocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Seco-type β-Apocarotenoid Generated by β-Carotene Oxidation Exerts Anti-inflammatory Effects against Activated Macrophages2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] n-3 Polyunsaturated fatty acid-enriched phosphatidylglycerol suppresses inflammation in RAW264.7 cells through Nrf2 activation via alteration of fatty acids in cellular phospholipids2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 北太平洋に分布する動物プランクトン群集の脂質特性分析2024

Author(s)

Takatani Naoki 高谷直己