TAKAHARA Mari 高原茉莉

Researcher Number	40804563
Other IDs
Affiliation (Current)	2025: 岡山大学, ヘルスシステム統合科学学域, 助教 2025: 北九州工業高等専門学校, 生産デザイン工学科, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 北九州工業高等専門学校, 生産デザイン工学科, 助教
Review Section/Research Field	Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / Biofunction/Bioprocess Except Principal Investigator Basic Section 90120:Biomaterials-related
Keywords	Principal Investigator 微生物由来トランスグルタミナーゼ / 脂質修飾 / 両親媒性ペプチド / リポソーム / 抗体 / イムノリポソーム / 核酸アプタマー / ナノバイオテクノロジー / 脂質化タンパク質 / 自己組織化 … More / 部位特異性 / タンパク質 / ペプチド / 酵素反応 / 部位特異生 / バイオコンジュゲーション / トランスグルタミナーゼ / 細胞接着 / 薬物送達 / 脂質 … More Except Principal Investigator 抗原ペプチド / 多糖 / ペプチド / 免疫療法 / ヒアルロン酸 / 抗原提示 / がんワクチン / 薬物送達システム Less

Development of antigeni modificaiton system to enhance effect of cancer vaccine
- Principal Investigator
  
  Mochizuki Shinichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Kitakyushu
Site-specific lipidation of antibodies for immunoliposome-like anti-cancer drugsPrincipal Investigator
- Principal Investigator
  
  高原茉莉
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kitakyushu National College of Technology
Development of site-specifically lipidated antigen and DNA for cancer vaccine liposomePrincipal Investigator
- Principal Investigator
  
  TAKAHARA Mari
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Kitakyushu National College of Technology

All 2024 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] 細胞・生体分子の固定化と機能発現2018
- Author(s)
  （監修）黒田章夫、（第５章共著）高原茉莉、神谷典穂
- Total Pages
  294
- Publisher
  シーエムシー出版
- ISBN
  9784781313269
- Data Source
  KAKENHI-PROJECT-17H07320
[Journal Article] Extending the Half-Life of a Protein in Vivo by Enzymatic Labeling with Amphiphilic Lipopeptides2021
- Author(s)
  Mari Takahara , Shinichi Mochizuki , Rie Wakabayashi , Kosuke Minamihata , Masahiro Goto , Kazuo Sakurai , Noriho Kamiya
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: accepted Issue: 4 Pages: 655-660
- DOI
  10.1021/acs.bioconjchem.1c00027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15369, KAKENHI-PROJECT-18K12082, KAKENHI-PROJECT-19H00841
[Journal Article] Synthetic Strategies for Artificial Lipidation of Functional Proteins.2020
- Author(s)
  Mari Takahara, Noirho Kamiya
- Journal Title
  
  Chemistry-A European Journal
  
  Volume: 26 Issue: 21 Pages: 4645-4655
- DOI
  10.1002/chem.201904568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15369, KAKENHI-PROJECT-19H00841
[Journal Article] Enzymatic cell-surface decoration with proteins using amphiphilic lipid-fused peptide substrates2019
- Author(s)
  Takahara Mari、Wakabayashi Rie、Fujimoto Naoki、Minamihata Kosuke、Goto Masahiro、Kamiya Noriho
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: － Issue: 30 Pages: 7315-7321
- DOI
  10.1002/chem.201900370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04581, KAKENHI-PROJECT-17H07320
[Journal Article] Design of Lipid?Protein Conjugates Using Amphiphilic Peptide Substrates of Microbial Transglutaminase2018
- Author(s)
  Takahara Mari、Wakabayashi Rie、Minamihata Kosuke、Goto Masahiro、Kamiya Noriho
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 1 Issue: 6 Pages: 1823-1829
- DOI
  10.1021/acsabm.8b00271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04581, KAKENHI-PROJECT-17H07320
[Journal Article] Primary Amine-Clustered DNA Aptamer for DNA?Protein Conjugation Catalyzed by Microbial Transglutaminase2017
- Author(s)
  Takahara Mari、Wakabayashi Rie、Minamihata Kosuke、Goto Masahiro、Kamiya Noriho
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 28 Issue: 12 Pages: 2954-2961
- DOI
  10.1021/acs.bioconjchem.7b00594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04581, KAKENHI-PROJECT-17H07320
[Presentation] トランスグルタミナーゼよる抗体脂質修飾法の検討2024
- Author(s)
  高原茉莉, 神谷典穂
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] Enzymatic labeling of a protein with lipopeptides for albumin interaction2020
- Author(s)
  Mari Takahara, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya
- Organizer
  ACS Fall 2020 National Meeting
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 化学工学会第51回秋季大会 (化学工学会第85年会の再公演) 2020年9月26日招待有り酵素反応による水溶性脂質化タンパク質の合成2020
- Author(s)
  高原茉莉, 若林里衣, 後藤雅宏, 神谷典穂
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 翻訳後修飾酵素を用いたタンパク質の人工脂質修飾プロセス2020
- Author(s)
  高原茉莉, 若林里衣, 後藤雅宏, 神谷典穂
- Organizer
  MRM Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 酵素反応による部位特異的なタンパク質ジアシル化法の開発2020
- Author(s)
  高原茉莉, 若林里衣, 南畑孝介, 後藤雅宏, 神谷典穂
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 両親媒性リポペプチドを用いた酵素反応による脂質化タンパク質合成2020
- Author(s)
  高原茉莉, 若林里衣, 後藤雅宏, 神谷典穂
- Organizer
  第30回日本MRS年次大会
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 細胞表面へのin situタンパク質ラベルを志向した両親媒性ペプチドの開発2019
- Author(s)
  高原茉莉, 若林里衣, 南畑孝介, 後藤雅宏, 神谷典穂
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] Transglutaminase-mediated lipid bilayer decoration with proteins using lipid-fused peptide amphiphile substrates2019
- Author(s)
  Mari Takahara, Rie Wakabayashi, Kosuke Minamihata, Masahiro Goto and Noriho Kamiya
- Organizer
  American Chemica Society (ACS) Fall 2019 National Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] Enzymatic cell-surface decoration with a functional protein using amphiphilic lipid-fused peptide substrates2019
- Author(s)
  高原茉莉、藤本直樹、若林里衣、南畑孝介、後藤雅宏、神谷典穂
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-17H07320
[Presentation] In situ cell-surface decoration with a protein using amphiphilic enzyme substrates2019
- Author(s)
  Mari Takahara, Rie Wakabayashi, Kosuke Minamihata, Masahiro Goto and Noriho Kamiya
- Organizer
  he 18th Asian Pacific Confederation of Chemical Engineering Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 細胞表面で機能するタンパク質とその人工合成2019
- Author(s)
  高原茉莉
- Organizer
  高分子学会九州支部フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17H07320
[Presentation] Peptide Amphiphiles for Site-Specific Protein-Drug Conjugates2019
- Author(s)
  Tenki Miura, Noriho Kamiya and Mari Takahara
- Organizer
  The Twelfth Japan-Korea Joint Symposium on Bio-microsensing Technology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 酵素反応で合成した脂質化タンパク質による細胞表面修飾2019
- Author(s)
  高原茉莉, 若林里衣, 南畑孝介, 後藤雅宏, 神谷典穂
- Organizer
  第29回日本MRS年次大会
- Data Source
  KAKENHI-PROJECT-19K15369
[Presentation] 抗体定常領域との部位特異的複合化によるDNAアプタマーの高機能化2018
- Author(s)
  高原茉莉、南畑孝介、若林里衣、後藤雅宏、日下部宜宏、李在萬、神谷典穂
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-17H07320
[Presentation] 抗体定常領域との複合化を介した高機能化核酸アプタマーの設計2018
- Author(s)
  高原茉莉、南畑孝介、若林里衣、後藤雅宏、日下部宜宏、李在萬、神谷典穂
- Organizer
  日本化学会第98春季年会2018
- Data Source
  KAKENHI-PROJECT-17H07320
[Presentation] Design of Amphiphilic Lipid-fused Peptide Substrates for Enzymatic Protein Lipidation2018
- Author(s)
  高原茉莉、若林里衣、南畑孝介、後藤雅宏、神谷典穂
- Organizer
  第28回日本MRS年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07320
[Presentation] 一級アミン集積化によるトランスグルタミナーゼ高反応性基質の探索2017
- Author(s)
  高原茉莉、若林里衣、南畑孝介、後藤雅宏、神谷典穂
- Organizer
  第24回日本生物工学会九州支部沖縄大会 (2017)
- Data Source
  KAKENHI-PROJECT-17H07320
[Presentation] Transglutaminase-mediated conjugation of DNA-(protein)n polymer using primary amine clustered substrates.2017
- Author(s)
  高原茉莉、若林里衣、南畑孝介、後藤雅宏、神谷典穂
- Organizer
  2017 九州・西部-釜山・慶南高分子(第18回)繊維(第16回)合同シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07320

1. Mochizuki Shinichi (10520702)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KAMIYA Noriho

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. GOTO Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. SAKURAI Kazuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 若林里衣

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

TAKAHARA Mari 高原 茉莉

Research Projects

Research Products

Co-Researchers

Development of antigeni modificaiton system to enhance effect of cancer vaccine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Site-specific lipidation of antibodies for immunoliposome-like anti-cancer drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of site-specifically lipidated antigen and DNA for cancer vaccine liposomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞・生体分子の固定化と機能発現2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Extending the Half-Life of a Protein in Vivo by Enzymatic Labeling with Amphiphilic Lipopeptides2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthetic Strategies for Artificial Lipidation of Functional Proteins.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enzymatic cell-surface decoration with proteins using amphiphilic lipid-fused peptide substrates2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Design of Lipid?Protein Conjugates Using Amphiphilic Peptide Substrates of Microbial Transglutaminase2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Primary Amine-Clustered DNA Aptamer for DNA?Protein Conjugation Catalyzed by Microbial Transglutaminase2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] トランスグルタミナーゼよる抗体脂質修飾法の検討2024

Author(s)

Organizer

Data Source

[Presentation] Enzymatic labeling of a protein with lipopeptides for albumin interaction2020

Author(s)

Organizer

Data Source

[Presentation] 化学工学会第51回秋季大会 (化学工学会 第85年会の再公演) 2020年9月26日 招待有り 酵素反応による水溶性脂質化タンパク質の合成2020

Author(s)

Organizer

Data Source

[Presentation] 翻訳後修飾酵素を用いたタンパク質の人工脂質修飾プロセス2020

Author(s)

Organizer

Data Source

[Presentation] 酵素反応による部位特異的なタンパク質ジアシル化法の開発2020

Author(s)

Organizer

Data Source

[Presentation] 両親媒性リポペプチドを用いた酵素反応による脂質化タンパク質合成2020

Author(s)

Organizer

Data Source

[Presentation] 細胞表面へのin situタンパク質ラベルを志向した両親媒性ペプチドの開発2019

Author(s)

Organizer

TAKAHARA Mari 高原茉莉

[Presentation] 化学工学会第51回秋季大会 (化学工学会第85年会の再公演) 2020年9月26日招待有り酵素反応による水溶性脂質化タンパク質の合成2020