Ishida Yusuke 石田裕介

Researcher Number	40805884
Affiliation (Current)	2025: 昭和大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 東京医科大学, 医学部, 講師 2017 – 2019: 東京医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology
Keywords	Principal Investigator Sirtuin3 / 敗血症関連脳障害 / シクロフィリン / ＤＮＡチップ解析 / メタボローム / サイトカイン / 敗血症性関連脳障害 / ミトコンドリア / 敗血症性関連脳傷害 / シクロフィリンD / 敗血症 … More Except Principal Investigator … More 敗血症性脳症 / ミトコンドリア機能不全 / オートファジー / アポトーシス / 敗血症関連脳症 / シクロフィリンD / Oxygraph-2k / mPTP / propofol / anesthetics / mitochondria / 電顕 / MPT pore / ケモカイン / サイトカイン / Protein array / microRNA / NRF2 / Cyclophilin D KOマウス / 酸化ストレス / CyclophilinD KO マウス / マイトファゴソーム / シクロフィリンD KOマウス / ミトファジー / 敗血症 / マイトファジー / ミトコンドリア / シクロフィリンＤ / 細胞死・アポトーシス実行経路 / ミトコンドリア・Cyclophilin D / ERAD / メタボローム / CypD KOマウス / CypDKOマウス / CLPモデル / mitophagy / Casapse / CyclophilinD / SAE / MPT / メタボローム解析 / CLPモデル / CypD Less

麻酔薬による脳保護あるいは脳障害作用のメカニズム解明
- Principal Investigator
  
  柴田勝一郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokyo Medical University
New approach for the mechanisms of septic encephalopathy based on cyclophilin D signal transduction and mitochondrial permeabilty transition pore structure
- Principal Investigator
  
  Hiroyuki Uchino
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokyo Medical University
Linkage analysis of Cyclophilin D / Surtuin 3 signaling system in sepsis-associated brain dysfunctionPrincipal Investigator
- Principal Investigator
  
  Ishida Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokyo Medical University
Investigation for the role of mitochondrial dysfunction and ER stress on SAE
- Principal Investigator
  
  Uchino Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Tokyo Medical University

All 2022 2021 2019 2018

All Journal Article Presentation

[Journal Article] Disease Outcome and Brain Metabolomics of Cyclophilin-D Knockout Mice in Sepsis2022
- Author(s)
  Takayuki Kobayashi , Hiroyuki Uchino , Eskil Elmr , Yukihiko Ogihara , Hidetoshi Fujita , Shusuke Sekine , Yusuke Ishida , Iwao Saiki , Shoichiro Shibata , Aya Kawachi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 2 Pages: 961-961
- DOI
  10.3390/ijms23020961
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18307, KAKENHI-PROJECT-20K09255, KAKENHI-PROJECT-20K17822
[Journal Article] 敗血症性脳症2021
- Author(s)
  石田裕介、小林賢礼、内野博之
- Journal Title
  
  救急・集中治療
  
  Volume: 33 Pages: 268-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18307
[Journal Article] The NRF2-PGC-1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, synoviolin, in a cecal ligation/perforation-;induced septic mouse model.2018
- Author(s)
  Ishida Y, Fujita H, Aratani S, Chijiiwa M, Taniguchi N, Yokota M, Ogihara Y, Uoshima N, Nagashima F, Uchino H, Nakajima T.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 18 Pages: 2467-2475
- DOI
  10.3892/mmr.2018.9175
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11062, KAKENHI-PROJECT-18K09036
[Presentation] 敗血症性脳症発症における分子機序2022
- Author(s)
  石田裕介
- Organizer
  集中治療医学会
- Data Source
  KAKENHI-PROJECT-19K18307
[Presentation] 敗血症関連脳症発症におけるCyclophilinD遺伝子欠損マウスを用いた脳内サイトカイン発現の検証2021
- Author(s)
  小林賢礼、河内文、魚島直美、柴田勝一郎、石田裕介、藤田英俊、中島利博、内野博之
- Organizer
  第４７回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09255
[Presentation] Cyclophilin D遺伝子欠損マウスを用いたCLP誘発敗血症関連脳症の発症機序に対するメタボローム解析2019
- Author(s)
  小林賢礼, 内野博之, 中島利博, 藤田英俊, 石田裕介, 魚島直美, 千々岩みゆき
- Organizer
  第２３回日本神経麻酔集中治療学会
- Data Source
  KAKENHI-PROJECT-17K11062

1. Uchino Hiroyuki (60266476)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 小林賢礼 (80837724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 柴田勝一郎 (70869429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 魚島直美 (20792211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 西山遼太 (60795607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 千々岩みゆき (80407080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 河内文 (60897932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 杉本昌弘 (30458963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ishida Yusuke 石田 裕介

Research Projects

Research Products

Co-Researchers

麻酔薬による脳保護あるいは脳障害作用のメカニズム解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New approach for the mechanisms of septic encephalopathy based on cyclophilin D signal transduction and mitochondrial permeabilty transition pore structure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Linkage analysis of Cyclophilin D / Surtuin 3 signaling system in sepsis-associated brain dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation for the role of mitochondrial dysfunction and ER stress on SAE

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Disease Outcome and Brain Metabolomics of Cyclophilin-D Knockout Mice in Sepsis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 敗血症性脳症2021

Author(s)

Journal Title

Data Source

[Journal Article] The NRF2-PGC-1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, synoviolin, in a cecal ligation/perforation-;induced septic mouse model.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 敗血症性脳症発症における分子機序2022

Author(s)

Organizer

Data Source

[Presentation] 敗血症関連脳症発症におけるCyclophilinD遺伝子欠損マウスを用いた脳内サイトカイン発現の検証2021

Author(s)

Organizer

Data Source

[Presentation] Cyclophilin D遺伝子欠損マウスを用いたCLP誘発敗血症関連脳症の発症機序に対するメタボローム解析2019

Author(s)

Organizer

Data Source

Ishida Yusuke 石田裕介